S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3

Nature Immunology

Volumn 17, Issue 5, 2016, Pages 514-522

  Wang, Fuan ^a,b   Alain, Tommy ^c   Szretter, Kristy J ^d   Stephenson, Kyle ^a,b   Pol, Jonathan G ^a,b   Atherton, Matthew J ^a,b   Hoang, Huy Dung ^c   Fonseca, Bruno D ^c   Zakaria, Chadi ^e   Chen, Lan ^a,b   Rangwala, Zainab ^a,b   Hesch, Adam ^a,b   Chan, Eva Sin Yan ^a,b   Tuinman, Carly ^a,b   Suthar, Mehul S ^f   Jiang, Zhaozhao ^g   Ashkar, Ali A ^a,b   Thomas, George ^h,i,j   Kozma, Sara C ^h,i   Gale, Michael ^k   Fitzgerald, Katherine A ^g   Diamond, Michael S ^d   Mossman, Karen ^a,b   Sonenberg, Nahum ^e   Wan, Yonghong ^a,b   Lichty, Brian D ^a,b   more..

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^h UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

ⁱ BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^j UNIVERSITY OF BARCELONA   (Spain)

^k UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; INTERFERON REGULATORY FACTOR 3; PROTEIN KINASE; RETINOIC ACID INDUCIBLE PROTEIN I; S6K1 KINASE; STING PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; DNA; IRF3 PROTEIN, MOUSE; MB21D1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE; OVALBUMIN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; RPS6KA1 PROTEIN, MOUSE; S6 KINASE; TBK1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELLULAR IMMUNITY; DNA VIRUS; GENE EXPRESSION; HEK293 CELL LINE; IMMUNOBLOTTING; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; WILD TYPE; ADENOVIRIDAE; ANIMAL; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; CYTOSOL; DENDRITIC CELL; GENETICS; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; IMMUNIZATION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROCEDURES; VIROLOGY;

ADENOVIRIDAE; ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; CYTOSOL; DENDRITIC CELLS; DNA; HEK293 CELLS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNIZATION; IMMUNOBLOTTING; INTERFERON REGULATORY FACTOR-3; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEOTIDYLTRANSFERASES; OVALBUMIN; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA;

EID: 84962110317     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3433     Document Type: Article

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