Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

Science

Volumn 341, Issue 6152, 2013, Pages 1390-1394

  Li, Xiao Dong ^a   Wu, Jiaxi ^a   Gao, Daxing ^a   Wang, Hua ^a   Sun, Lijun ^a   Chen, Zhijian J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BETA INTERFERON; DNA VACCINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERFERON; INTERFERON REGULATORY FACTOR 3; TOLL LIKE RECEPTOR 9; VALACICLOVIR; VIRUS PROTEIN;

ANTIBODY; CYTOPLASM; DNA; IMMUNE RESPONSE; IMMUNE SYSTEM; SIGNALING; VIRUS;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYCLIC GUANOSINE ADENOSINE MONOPHOSPHATE SYNTHASE; CYCLIC GUANOSINE ADENOSINE SYNTHASE; CYTOKINE RESPONSE; DENDRITIC CELL; DIMERIZATION; DNA TRANSFECTION; DNA VIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HERPES SIMPLEX VIRUS 1; LUNG FIBROBLAST; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENDAI VIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; VACCINIA VIRUS;

ANIMALIA; DNA VIRUSES; HUMAN HERPESVIRUS 1; MUS;

EID: 84884675857     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1244040     Document Type: Article

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