Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS

Journal of Immunology

Volumn 194, Issue 4, 2015, Pages 1545-1554

  Ma, Feng ^a   Li, Bing ^a   Liu, Su Yang ^a   Iyer, Shankar S ^a   Yu, Yongxin ^b   Wu, Aiping ^a   Cheng, Genhong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Division of Oral Biology and Medicine School of Dentistry Broad Stem Cell Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP AMP SYNTHASE; INTERFERON; LIPID A; LIPOPOLYSACCHARIDE; PATTERN RECOGNITION RECEPTOR; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); POLYINOSINIC POLYCYTIDYLIC ACID; SYNTHETASE; UNCLASSIFIED DRUG; VIRUS DNA; MB21D1 PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYCLIC GMP AMP SYNTHASE GENE; CYTOKINE PRODUCTION; DDX41 GENE; DNA STRUCTURE; GENE; GENE EXPRESSION; GENE INDUCTION; GENE SILENCING; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; INTERFERON SENSITIVE RESPONSE ELEMENT; MACROPHAGE; MALE; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEEDBACK SYSTEM; IMMUNOBLOTTING; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEEDBACK, PHYSIOLOGICAL; HUMANS; IMMUNITY, INNATE; IMMUNOBLOTTING; INTERFERON TYPE I; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEOTIDYLTRANSFERASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84922551625     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402066     Document Type: Article

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