Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING

Nucleic Acids Research

Volumn 42, Issue 13, 2014, Pages 8243-8257

  Wu, Xiaomei ^a   Wu, Fei Hua ^a,b   Wang, Xiaoqiang ^c   Wang, Lilin ^a   Siedow, James N ^b   Zhang, Weiguo ^d   Pei, Zhen Ming ^a,b  

^a HANGZHOU NORMAL UNIVERSITY   (China)

^b DUKE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH TEXAS   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CGAS PROTEIN; CYCLIC GMP; INTERFERON; MEMBRANE PROTEIN; NUCLEOTIDYLTRANSFERASE; STING PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA BINDING; EUKARYOTE EVOLUTION; HUMAN; INNATE IMMUNITY; INVERTEBRATE; MOLECULAR EVOLUTION; MONOSIGA BREVICOLLIS; MOUSE; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VERTEBRATE;

ANIMALS; CHOANOFLAGELLATA; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; HUMANS; MEMBRANE PROTEINS; MICE; NEMATODA; NUCLEOTIDYLTRANSFERASES; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 84905581650     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku569     Document Type: Article

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