iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING

Nature Immunology

Volumn 17, Issue 9, 2016, Pages 1057-1066

  Luo, Wei Wei ^a   Li, Shu ^a   Li, Chen ^a   Lian, Huan ^a   Yang, Qing ^a   Zhong, Bo ^a   Shu, Hong Bing ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EIF3S5 ENZYME; ENZYME; INACTIVE RHOMBOID PROTEIN 2; INTERFERON; MEMBRANE PROTEIN; POLYUBIQUITIN; PROTEIN; STING PROTEIN; TRANSLOCON; TRANSLOCON ASSOCIATED PROTEIN BETA; UNCLASSIFIED DRUG; VIRUS DNA; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ACP5 PROTEIN, MOUSE; CARRIER PROTEIN; INITIATION FACTOR 3; IRHOM2 PROTEIN, MOUSE; MPYS PROTEIN, MOUSE; PROTEIN BINDING;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1 INFECTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; MICROSOME; PERINUCLEAR MICROSOME; PRIORITY JOURNAL; PROTEIN STABILITY; ANIMAL; C57BL MOUSE; CELL CULTURE; GENETICS; HERPES SIMPLEX VIRUS 1; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MOUSE; PROTEIN TRANSPORT; UBIQUITINATION;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; EUKARYOTIC INITIATION FACTOR-3; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNITY, INNATE; INTERFERON TYPE I; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSOMES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN TRANSPORT; TARTRATE-RESISTANT ACID PHOSPHATASE; UBIQUITINATION;

EID: 84978699224     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3510     Document Type: Article

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