-
1
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa H, Barber GN, (2008) STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455: 674-678
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
2
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type i interferon-dependent innate immunity
-
Ishikawa H, Ma Z, Barber GN, (2009) STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461: 788-792
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
3
-
-
49449115516
-
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals
-
Jin L, Waterman PM, Jonscher KR, Short CM, Reisdorph NA, Cambier JC, (2008) MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals. Mol Cell Biol 28: 5014-5026
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5014-5026
-
-
Jin, L.1
Waterman, P.M.2
Jonscher, K.R.3
Short, C.M.4
Reisdorph, N.A.5
Cambier, J.C.6
-
4
-
-
66649109939
-
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
-
Sun W, Li Y, Chen L, Chen H, You F, Zhou X, Zhou Y, Zhai Z, Chen D, Jiang Z, (2009) ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci USA 106: 8653-8658
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8653-8658
-
-
Sun, W.1
Li, Y.2
Chen, L.3
Chen, H.4
You, F.5
Zhou, X.6
Zhou, Y.7
Zhai, Z.8
Chen, D.9
Jiang, Z.10
-
5
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, et al, (2008) The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 29: 538-550
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
Yang, Y.2
Li, S.3
Wang, Y.Y.4
Li, Y.5
Diao, F.6
Lei, C.7
He, X.8
Zhang, L.9
Tien, P.10
-
6
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu J, Sun L, Chen X, Du F, Shi H, Chen C, Chen ZJ, (2013) Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339: 826-830
-
(2013)
Science
, vol.339
, pp. 826-830
-
-
Wu, J.1
Sun, L.2
Chen, X.3
Du, F.4
Shi, H.5
Chen, C.6
Chen, Z.J.7
-
7
-
-
80054966913
-
STING is a direct innate immune sensor of cyclic di-GMP
-
Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE, (2011) STING is a direct innate immune sensor of cyclic di-GMP. Nature 478: 515-518
-
(2011)
Nature
, vol.478
, pp. 515-518
-
-
Burdette, D.L.1
Monroe, K.M.2
Sotelo-Troha, K.3
Iwig, J.S.4
Eckert, B.5
Hyodo, M.6
Hayakawa, Y.7
Vance, R.E.8
-
8
-
-
84876085954
-
STING recognition of cytoplasmic DNA instigates cellular defense
-
Abe T, Harashima A, Xia T, Konno H, Konno K, Morales A, Ahn J, Gutman D, Barber GN, (2013) STING recognition of cytoplasmic DNA instigates cellular defense. Mol Cell 50: 5-15
-
(2013)
Mol Cell
, vol.50
, pp. 5-15
-
-
Abe, T.1
Harashima, A.2
Xia, T.3
Konno, H.4
Konno, K.5
Morales, A.6
Ahn, J.7
Gutman, D.8
Barber, G.N.9
-
9
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, et al, (2010) IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol 11: 997-1004
-
(2010)
Nat Immunol
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
Sharma, S.6
Sirois, C.M.7
Jin, T.8
Latz, E.9
Xiao, T.S.10
-
10
-
-
80052969639
-
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
-
Zhang Z, Yuan B, Bao M, Lu N, Kim T, Liu YJ, (2011) The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat Immunol 12: 959-965
-
(2011)
Nat Immunol
, vol.12
, pp. 959-965
-
-
Zhang, Z.1
Yuan, B.2
Bao, M.3
Lu, N.4
Kim, T.5
Liu, Y.J.6
-
12
-
-
46249115827
-
Interferon-inducible antiviral effectors
-
Sadler AJ, Williams BR, (2008) Interferon-inducible antiviral effectors. Nat Rev Immunol 8: 559-568
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 559-568
-
-
Sadler, A.J.1
Williams, B.R.2
-
13
-
-
84870275730
-
Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
-
Brunette RL, Young JM, Whitley DG, Brodsky IE, Malik HS, Stetson DB, (2012) Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J Exp Med 209: 1969-1983
-
(2012)
J Exp Med
, vol.209
, pp. 1969-1983
-
-
Brunette, R.L.1
Young, J.M.2
Whitley, D.G.3
Brodsky, I.E.4
Malik, H.S.5
Stetson, D.B.6
-
14
-
-
84863285086
-
Systematic identification of type i and type II interferon-induced antiviral factors
-
Liu SY, Sanchez DJ, Aliyari R, Lu S, Cheng G, (2012) Systematic identification of type I and type II interferon-induced antiviral factors. Proc Natl Acad Sci USA 109: 4239-4244
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 4239-4244
-
-
Liu, S.Y.1
Sanchez, D.J.2
Aliyari, R.3
Lu, S.4
Cheng, G.5
-
15
-
-
0032434924
-
Positive feedback regulation of type i IFN genes by the IFN-inducible transcription factor IRF-7
-
Sato M, Hata N, Asagiri M, Nakaya T, Taniguchi T, Tanaka N, (1998) Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. FEBS Lett 441: 106-110
-
(1998)
FEBS Lett
, vol.441
, pp. 106-110
-
-
Sato, M.1
Hata, N.2
Asagiri, M.3
Nakaya, T.4
Taniguchi, T.5
Tanaka, N.6
-
16
-
-
0032538891
-
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
-
Marie I, Durbin JE, Levy DE, (1998) Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J 17: 6660-6669
-
(1998)
EMBO J
, vol.17
, pp. 6660-6669
-
-
Marie, I.1
Durbin, J.E.2
Levy, D.E.3
-
17
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
-
Sato M, Suemori H, Hata N, Asagiri M, Ogasawara K, Nakao K, Nakaya T, Katsuki M, Noguchi S, Tanaka N, et al, (2000) Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13: 539-548
-
(2000)
Immunity
, vol.13
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
Asagiri, M.4
Ogasawara, K.5
Nakao, K.6
Nakaya, T.7
Katsuki, M.8
Noguchi, S.9
Tanaka, N.10
-
18
-
-
77954070545
-
C-di-AMP secreted by intracellular Listeria monocytogenes activates a host type i interferon response
-
Woodward JJ, Iavarone AT, Portnoy DA, (2010) c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328: 1703-1705
-
(2010)
Science
, vol.328
, pp. 1703-1705
-
-
Woodward, J.J.1
Iavarone, A.T.2
Portnoy, D.A.3
-
19
-
-
63049137897
-
Principles of c-di-GMP signalling in bacteria
-
Hengge R, (2009) Principles of c-di-GMP signalling in bacteria. Nat Rev Microbiol 7: 263-273
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 263-273
-
-
Hengge, R.1
-
20
-
-
63749115101
-
Bacterial nucleotide-based second messengers
-
Pesavento C, Hengge R, (2009) Bacterial nucleotide-based second messengers. Curr Opin Microbiol 12: 170-176
-
(2009)
Curr Opin Microbiol
, vol.12
, pp. 170-176
-
-
Pesavento, C.1
Hengge, R.2
-
21
-
-
84880426658
-
The cGAS-STING pathway for DNA sensing
-
Xiao TS, Fitzgerald KA, (2013) The cGAS-STING pathway for DNA sensing. Mol Cell 51: 135-139
-
(2013)
Mol Cell
, vol.51
, pp. 135-139
-
-
Xiao, T.S.1
Fitzgerald, K.A.2
-
22
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S, (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
23
-
-
34548608447
-
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
-
Jin MS, Kim SE, Heo JY, Lee ME, Kim HM, Paik SG, Lee H, Lee JO, (2007) Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 130: 1071-1082
-
(2007)
Cell
, vol.130
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
Lee, M.E.4
Kim, H.M.5
Paik, S.G.6
Lee, H.7
Lee, J.O.8
-
24
-
-
84886789626
-
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling
-
Konno H, Konno K, Barber GN, (2013) Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling. Cell 155: 688-698
-
(2013)
Cell
, vol.155
, pp. 688-698
-
-
Konno, H.1
Konno, K.2
Barber, G.N.3
-
25
-
-
78650214109
-
The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA
-
Tsuchida T, Zou J, Saitoh T, Kumar H, Abe T, Matsuura Y, Kawai T, Akira S, (2010) The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA. Immunity 33: 765-776
-
(2010)
Immunity
, vol.33
, pp. 765-776
-
-
Tsuchida, T.1
Zou, J.2
Saitoh, T.3
Kumar, H.4
Abe, T.5
Matsuura, Y.6
Kawai, T.7
Akira, S.8
-
26
-
-
84865270570
-
TRIM32 protein modulates type i interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination
-
Zhang J, Hu MM, Wang YY, Shu HB, (2012) TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination. J Biol Chem 287: 28646-28655
-
(2012)
J Biol Chem
, vol.287
, pp. 28646-28655
-
-
Zhang, J.1
Hu, M.M.2
Wang, Y.Y.3
Shu, H.B.4
-
27
-
-
62049084519
-
The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA
-
Zhong B, Zhang L, Lei C, Li Y, Mao AP, Yang Y, Wang YY, Zhang XL, Shu HB, (2009) The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity 30: 397-407
-
(2009)
Immunity
, vol.30
, pp. 397-407
-
-
Zhong, B.1
Zhang, L.2
Lei, C.3
Li, Y.4
Mao, A.P.5
Yang, Y.6
Wang, Y.Y.7
Zhang, X.L.8
Shu, H.B.9
-
28
-
-
33745752255
-
Automatic transcription factor classifier based on functional domain composition
-
Qian Z, Cai YD, Li Y, (2006) Automatic transcription factor classifier based on functional domain composition. Biochem Biophys Res Commun 347: 141-144
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 141-144
-
-
Qian, Z.1
Cai, Y.D.2
Li, Y.3
-
29
-
-
0037208166
-
TRANSFAC: Transcriptional regulation, from patterns to profiles
-
Matys V, Fricke E, Geffers R, Gossling E, Haubrock M, Hehl R, Hornischer K, Karas D, Kel AE, Kel-Margoulis OV, et al, (2003) TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res 31: 374-378
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 374-378
-
-
Matys, V.1
Fricke, E.2
Geffers, R.3
Gossling, E.4
Haubrock, M.5
Hehl, R.6
Hornischer, K.7
Karas, D.8
Kel, A.E.9
Kel-Margoulis, O.V.10
-
30
-
-
84855495283
-
IkappaB kinase epsilon (IKK(epsilon)) regulates the balance between type i and type II interferon responses
-
Ng SL, Friedman BA, Schmid S, Gertz J, Myers RM, Tenoever BR, Maniatis T, (2011) IkappaB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses. Proc Natl Acad Sci USA 108: 21170-21175
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 21170-21175
-
-
Ng, S.L.1
Friedman, B.A.2
Schmid, S.3
Gertz, J.4
Myers, R.M.5
Tenoever, B.R.6
Maniatis, T.7
-
31
-
-
84872522528
-
Latent enhancers activated by stimulation in differentiated cells
-
Ostuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, Bonifacio S, Curina A, Prosperini E, Ghisletti S, Natoli G, (2013) Latent enhancers activated by stimulation in differentiated cells. Cell 152: 157-171
-
(2013)
Cell
, vol.152
, pp. 157-171
-
-
Ostuni, R.1
Piccolo, V.2
Barozzi, I.3
Polletti, S.4
Termanini, A.5
Bonifacio, S.6
Curina, A.7
Prosperini, E.8
Ghisletti, S.9
Natoli, G.10
-
32
-
-
58049202272
-
Innate immunity to virus infection
-
Takeuchi O, Akira S, (2009) Innate immunity to virus infection. Immunol Rev 227: 75-86
-
(2009)
Immunol Rev
, vol.227
, pp. 75-86
-
-
Takeuchi, O.1
Akira, S.2
-
34
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
Platanias LC, (2005) Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 5: 375-386
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
35
-
-
84869794842
-
STING manifests self DNA-dependent inflammatory disease
-
Ahn J, Gutman D, Saijo S, Barber GN, (2012) STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci USA 109: 19386-19391
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 19386-19391
-
-
Ahn, J.1
Gutman, D.2
Saijo, S.3
Barber, G.N.4
-
36
-
-
84856301080
-
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease
-
Gall A, Treuting P, Elkon KB, Loo YM, Gale M Jr, Barber GN, Stetson DB, (2012) Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36: 120-131
-
(2012)
Immunity
, vol.36
, pp. 120-131
-
-
Gall, A.1
Treuting, P.2
Elkon, K.B.3
Loo, Y.M.4
Gale, Jr.M.5
Barber, G.N.6
Stetson, D.B.7
-
37
-
-
84905825645
-
Activated STING in a vascular and pulmonary syndrome
-
Liu Y, Jesus AA, Marrero B, Yang D, Ramsey SE, Montealegre Sanchez GA, Tenbrock K, Wittkowski H, Jones OY, Kuehn HS, et al, (2014) Activated STING in a vascular and pulmonary syndrome. N Engl J Med 371: 507-518
-
(2014)
N Engl J Med
, vol.371
, pp. 507-518
-
-
Liu, Y.1
Jesus, A.A.2
Marrero, B.3
Yang, D.4
Ramsey, S.E.5
Montealegre Sanchez, G.A.6
Tenbrock, K.7
Wittkowski, H.8
Jones, O.Y.9
Kuehn, H.S.10
-
38
-
-
84893817803
-
STING-dependent type i IFN production inhibits cell-mediated immunity to Listeria monocytogenes
-
Archer KA, Durack J, Portnoy DA, (2014) STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes. PLoS Pathog 10: e1003861
-
(2014)
PLoS Pathog
, vol.10
, pp. e1003861
-
-
Archer, K.A.1
Durack, J.2
Portnoy, D.A.3
-
39
-
-
0025861573
-
Tumoricidal alveolar macrophage and tumor infiltrating macrophage cell lines
-
Palleroni AV, Varesio L, Wright RB, Brunda MJ, (1991) Tumoricidal alveolar macrophage and tumor infiltrating macrophage cell lines. Int J Cancer 49: 296-302
-
(1991)
Int J Cancer
, vol.49
, pp. 296-302
-
-
Palleroni, A.V.1
Varesio, L.2
Wright, R.B.3
Brunda, M.J.4
-
40
-
-
84922165128
-
Retinoid X receptor alpha attenuates host antiviral response by suppressing type i interferon
-
Ma F, Liu SY, Razani B, Arora N, Li B, Kagechika H, Tontonoz P, Nunez V, Ricote M, Cheng G, (2014) Retinoid X receptor alpha attenuates host antiviral response by suppressing type I interferon. Nat Commun 5: 5494
-
(2014)
Nat Commun
, vol.5
, pp. 5494
-
-
Ma, F.1
Liu, S.Y.2
Razani, B.3
Arora, N.4
Li, B.5
Kagechika, H.6
Tontonoz, P.7
Nunez, V.8
Ricote, M.9
Cheng, G.10
-
41
-
-
44949231424
-
Analyzing real-time PCR data by the comparative C(T) method
-
Schmittgen TD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3: 1101-1108
-
(2008)
Nat Protoc
, vol.3
, pp. 1101-1108
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
42
-
-
84859320008
-
PrimerBank: A PCR primer database for quantitative gene expression analysis, 2012 update
-
Wang X, Spandidos A, Wang H, Seed B, (2012) PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update. Nucleic Acids Res 40: D1144-D1149
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D1144-D1149
-
-
Wang, X.1
Spandidos, A.2
Wang, H.3
Seed, B.4
-
43
-
-
62349130698
-
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
-
Langmead B, Trapnell C, Pop M, Salzberg SL, (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25
-
(2009)
Genome Biol
, vol.10
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
44
-
-
84892599558
-
A unique epigenetic signature is associated with active DNA replication loci in human embryonic stem cells
-
Li B, Su T, Ferrari R, Li JY, Kurdistani SK, (2014) A unique epigenetic signature is associated with active DNA replication loci in human embryonic stem cells. Epigenetics 9: 257-267
-
(2014)
Epigenetics
, vol.9
, pp. 257-267
-
-
Li, B.1
Su, T.2
Ferrari, R.3
Li, J.Y.4
Kurdistani, S.K.5
-
45
-
-
80052033649
-
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma
-
Ma F, Xu S, Liu X, Zhang Q, Xu X, Liu M, Hua M, Li N, Yao H, Cao X, (2011) The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma. Nat Immunol 12: 861-869
-
(2011)
Nat Immunol
, vol.12
, pp. 861-869
-
-
Ma, F.1
Xu, S.2
Liu, X.3
Zhang, Q.4
Xu, X.5
Liu, M.6
Hua, M.7
Li, N.8
Yao, H.9
Cao, X.10
|