Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 8, 2016, Pages E1034-E1043

  Zhang, Guigen ^a   Chan, Baca ^b   Samarina, Naira ^a   Abere, Bizunesh ^a   Weidner Glunde, Magdalena ^a   Buch, Anna ^a   Pich, Andreas ^a   Brinkmann, Melanie M ^a,b   Schulz, Thomas F ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Cyclic GMP AMP synthase; Cytoplasmic LANA

Indexed keywords

BETA INTERFERON; CYCLIC GMP; CYCLIC GMP AMP SYNTHASE; ENZYME; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2C; INTERFERON REGULATORY FACTOR 3; LATENCY ASSOCIATED NUCLEAR ANTIGEN; PROTEIN; STIMULATOR OF INTERFERON GENE; SYNTHETASE; TANK BINDING KINASE 1; UNCLASSIFIED DRUG; VIRUS PROTEIN; ISOPROTEIN; LATENCY-ASSOCIATED NUCLEAR ANTIGEN; MB21D1 PROTEIN, HUMAN; NUCLEAR PROTEIN; NUCLEOTIDYLTRANSFERASE; VIRUS ANTIGEN;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENZYME BINDING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; GENE SILENCING; GENETIC TRANSFECTION; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; IMMUNOPRECIPITATION; IN VITRO STUDY; INNATE IMMUNITY; INTERFERON PRODUCTION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; VERO CELL LINE; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS REPLICATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHLOROCEBUS AETHIOPS; CYTOPLASM; GENETICS; METABOLISM; PHYSIOLOGY; VIROLOGY;

ANIMALS; ANTIGENS, VIRAL; CERCOPITHECUS AETHIOPS; CYTOPLASM; HELA CELLS; HERPESVIRUS 8, HUMAN; HUMANS; NUCLEAR PROTEINS; NUCLEOTIDYLTRANSFERASES; PROTEIN ISOFORMS; VERO CELLS; VIRUS REPLICATION;

EID: 84959235484     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516812113     Document Type: Article

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