Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3', 3'-cGAMP)

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 7, 2016, Pages 1790-1795

  Hallberg, Zachary F ^a   Wang, Xin C ^a   Wright, Todd A ^a   Nan, Beiyan ^b   Ad, Omer ^a   Yeo, Jongchan ^a   Hammond, Ming C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Bacterial signaling; Cyclic dinucleotides; Fluorescent biosensor; Second messengers; Surface sensing

Indexed keywords

BACTERIAL ENZYME; CYCLIC AMP; CYCLIC GMP; GGDEF ENZYME; HOMODIMER; MONOMER; UNCLASSIFIED DRUG; CYCLIC GUANOSINE MONOPHOSPHATE-ADENOSINE MONOPHOSPHATE; CYCLIC NUCLEOTIDE; DIGUANYLATE CYCLASE; ESCHERICHIA COLI PROTEIN; LYASE;

ARTICLE; BIOINFORMATICS; BIOSENSOR; CELL LYSATE; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GEOBACTER SULFURREDUCENS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MYXOCOCCUS XANTHUS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; SEQUENCE ALIGNMENT; SIZE EXCLUSION CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; THIN LAYER CHROMATOGRAPHY; BIOSYNTHESIS; CHEMISTRY; DELTAPROTEOBACTERIA; ENZYMOLOGY; METABOLISM; PROTEIN CONFORMATION;

DELTAPROTEOBACTERIA; ESCHERICHIA COLI PROTEINS; NUCLEOTIDES, CYCLIC; PHOSPHORUS-OXYGEN LYASES; PROTEIN CONFORMATION;

EID: 84959440981     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1515287113     Document Type: Article

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