DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway

Science

Volumn 350, Issue 6260, 2015, Pages 568-571

  Lau, Aura ^a   Gray, Elizabeth E ^a   Brunette, Rebecca L ^a   Stetson, Daniel B ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GUANOSINE MONOPHOSPHATE ADENOSINE MONOPHOSPHATE SYNTHASE; E1A PROTEIN; ONCOPROTEIN; PROTEIN E7; PROTEIN STING; SYNTHETASE; UNCLASSIFIED DRUG; VIRUS DNA; CYCLIC GUANOSINE MONOPHOSPHATE-ADENOSINE MONOPHOSPHATE; CYCLIC NUCLEOTIDE; DNA; DNA BINDING PROTEIN; E7 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 18; MEMBRANE PROTEIN; MPYS PROTEIN, HUMAN; RETINOBLASTOMA PROTEIN;

CANCER; DNA; GENE EXPRESSION; GENETIC ANALYSIS; PROTEIN; TUMOR; VIRUS;

ADENOVIRIDAE; ARTICLE; DNA TUMOR VIRUS; GENE SILENCING; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; VIRUS ONCOGENE; WART VIRUS; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PROTEIN MOTIF; TUMOR ESCAPE;

ADENOVIRIDAE; DNA VIRUSES; HUMAN PAPILLOMAVIRUS;

ADENOVIRUS E1A PROTEINS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; DNA TUMOR VIRUSES; DNA, NEOPLASM; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; HEK293 CELLS; HELA CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; MEMBRANE PROTEINS; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR SEQUENCE DATA; NUCLEOTIDES, CYCLIC; ONCOGENE PROTEINS, VIRAL; RETINOBLASTOMA PROTEIN; TUMOR ESCAPE;

EID: 84945353895     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab3291     Document Type: Article

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