Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

Cell Host and Microbe

Volumn 17, Issue 6, 2015, Pages 820-828

  Collins, Angela C ^a   Cai, Haocheng ^b   Li, Tuo ^b   Franco, Luis H ^b   Li, Xiao Dong ^b   Nair, Vidhya R ^a   Scharn, Caitlyn R ^a   Stamm, Chelsea E ^a   Levine, Beth ^a,b   Chen, Zhijian J ^b   Shiloh, Michael U ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYCLIC GUANOSINE MONOPHOSPHATE ADENOSINE MONOPHOSPHATE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG; BACTERIAL DNA; DNA BINDING PROTEIN; ELF3 PROTEIN, HUMAN; MB21D1 PROTEIN, HUMAN; MB21D1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE INACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; LETHALITY; LUNG TUBERCULOSIS; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MORTALITY; MUTANT MOUSE STRAIN; TUBERCULOSIS;

ANIMALS; AUTOPHAGY; DNA, BACTERIAL; DNA-BINDING PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INTERFERON-BETA; MACROPHAGES; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MYCOBACTERIUM TUBERCULOSIS; NUCLEOTIDYLTRANSFERASES; PROTO-ONCOGENE PROTEINS C-ETS; TRANSCRIPTION FACTORS; TUBERCULOSIS;

EID: 84930260866     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2015.05.005     Document Type: Article

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