메뉴 건너뛰기




Volumn 4, Issue 1, 2016, Pages

Role of endoplasmic reticulum stress in drug-induced toxicity

Author keywords

Adverse effects; Drug; Endoplasmic reticulum; ER stress; Liver; Toxicity

Indexed keywords

AMIODARONE; ARSENIC TRIOXIDE; BLEOMYCIN; BORTEZOMIB; CISPLATIN; CLOZAPINE; CYCLOSPORIN; DICLOFENAC; EFAVIRENZ; ERLOTINIB; FUROSEMIDE; INDOMETACIN; OLANZAPINE; PACLITAXEL; PARACETAMOL; PROTEINASE INHIBITOR; SERTRALINE; THAPSIGARGIN; TROGLITAZONE; TUNICAMYCIN; ZIDOVUDINE;

EID: 84979779675     PISSN: None     EISSN: 20521707     Source Type: Journal    
DOI: 10.1002/prp2.211     Document Type: Review
Times cited : (184)

References (345)
  • 1
    • 0037038669 scopus 로고    scopus 로고
    • Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
    • Amuthan G, Biswas G, Ananadatheerthavarada HK, Vijayasarathy C, Shephard HM, Avadhani NG (2002). Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 21: 7839-7849.
    • (2002) Oncogene , vol.21 , pp. 7839-7849
    • Amuthan, G.1    Biswas, G.2    Ananadatheerthavarada, H.K.3    Vijayasarathy, C.4    Shephard, H.M.5    Avadhani, N.G.6
  • 3
    • 77954878639 scopus 로고    scopus 로고
    • Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells
    • Apostolova N, Gomez-Sucerquia LJ, Moran A, Alvarez A, Blas-Garcia A, Esplugues JV (2010). Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells. Br J Pharmacol 160: 2069-2084.
    • (2010) Br J Pharmacol , vol.160 , pp. 2069-2084
    • Apostolova, N.1    Gomez-Sucerquia, L.J.2    Moran, A.3    Alvarez, A.4    Blas-Garcia, A.5    Esplugues, J.V.6
  • 7
    • 80255136273 scopus 로고    scopus 로고
    • Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals
    • Avadhani NG, Sangar MC, Bansal S, Bajpai P (2011). Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals. FEBS J 278: 4218-4229.
    • (2011) FEBS J , vol.278 , pp. 4218-4229
    • Avadhani, N.G.1    Sangar, M.C.2    Bansal, S.3    Bajpai, P.4
  • 8
    • 79952756154 scopus 로고    scopus 로고
    • Role of biotransformation in drug-induced toxicity: influence of intra- and inter-species differences in drug metabolism
    • Baillie TA, Rettie AE (2011). Role of biotransformation in drug-induced toxicity: influence of intra- and inter-species differences in drug metabolism. Drug Metab Pharmacokinet 26: 15-29.
    • (2011) Drug Metab Pharmacokinet , vol.26 , pp. 15-29
    • Baillie, T.A.1    Rettie, A.E.2
  • 9
    • 84885397513 scopus 로고    scopus 로고
    • Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators
    • Banerjee A, Abdelmegeed MA, Jang S, Song BJ (2013). Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS ONE 8: e76850.
    • (2013) PLoS ONE , vol.8
    • Banerjee, A.1    Abdelmegeed, M.A.2    Jang, S.3    Song, B.J.4
  • 10
    • 0029090947 scopus 로고
    • Diclofenac-associated hepatotoxicity: analysis of 180 cases reported to the Food and Drug Administration as adverse reactions
    • Banks AT, Zimmerman HJ, Ishak KG, Harter JG (1995). Diclofenac-associated hepatotoxicity: analysis of 180 cases reported to the Food and Drug Administration as adverse reactions. Hepatology 22: 820-827.
    • (1995) Hepatology , vol.22 , pp. 820-827
    • Banks, A.T.1    Zimmerman, H.J.2    Ishak, K.G.3    Harter, J.G.4
  • 11
    • 0025976375 scopus 로고
    • Influences of Ginkgo biloba on cyclosporin a induced lipid peroxidation in human liver microsomes in comparison to vitamin E, glutathione and N-acetylcysteine
    • Barth SA, Inselmann G, Engemann R, Heidemann HT (1991). Influences of Ginkgo biloba on cyclosporin a induced lipid peroxidation in human liver microsomes in comparison to vitamin E, glutathione and N-acetylcysteine. Biochem Pharmacol 41: 1521-1526.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1521-1526
    • Barth, S.A.1    Inselmann, G.2    Engemann, R.3    Heidemann, H.T.4
  • 12
    • 84875435582 scopus 로고    scopus 로고
    • Risk of cardiovascular disease from antiretroviral therapy for HIV: a systematic review
    • Bavinger C, Bendavid E, Niehaus K, Olshen RA, Olkin I, Sundaram V, et al. (2013). Risk of cardiovascular disease from antiretroviral therapy for HIV: a systematic review. PLoS ONE 8: e59551.
    • (2013) PLoS ONE , vol.8
    • Bavinger, C.1    Bendavid, E.2    Niehaus, K.3    Olshen, R.A.4    Olkin, I.5    Sundaram, V.6
  • 13
    • 79952702137 scopus 로고    scopus 로고
    • Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver
    • Begriche K, Massart J, Robin MA, Borgne-Sanchez A, Fromenty B (2011). Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 54: 773-794.
    • (2011) J Hepatol , vol.54 , pp. 773-794
    • Begriche, K.1    Massart, J.2    Robin, M.A.3    Borgne-Sanchez, A.4    Fromenty, B.5
  • 14
    • 23744461982 scopus 로고    scopus 로고
    • Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion
    • Benali-Furet NL, Chami M, Houel L, De Giorgi F, Vernejoul F, Lagorce D, et al. (2005). Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion. Oncogene 24: 4921-4933.
    • (2005) Oncogene , vol.24 , pp. 4921-4933
    • Benali-Furet, N.L.1    Chami, M.2    Houel, L.3    De Giorgi, F.4    Vernejoul, F.5    Lagorce, D.6
  • 15
    • 84939801421 scopus 로고    scopus 로고
    • Dysregulation of endoplasmic reticulum stress and autophagic responses by the antiretroviral drug efavirenz
    • Bertrand L, Toborek M (2015). Dysregulation of endoplasmic reticulum stress and autophagic responses by the antiretroviral drug efavirenz. Mol Pharmacol 88: 304-315.
    • (2015) Mol Pharmacol , vol.88 , pp. 304-315
    • Bertrand, L.1    Toborek, M.2
  • 16
    • 0016827217 scopus 로고
    • Tunicamycin, an inhibitor of Bacillus peptidoglycan synthesis: a new site of inhibition
    • Bettinger GE, Young FE (1975). Tunicamycin, an inhibitor of Bacillus peptidoglycan synthesis: a new site of inhibition. Biochem Biophys Res Commun 67: 16-21.
    • (1975) Biochem Biophys Res Commun , vol.67 , pp. 16-21
    • Bettinger, G.E.1    Young, F.E.2
  • 17
    • 84918771672 scopus 로고    scopus 로고
    • Synthesis, processing, and function of N-glycans in N-glycoproteins
    • Bieberich E (2014). Synthesis, processing, and function of N-glycans in N-glycoproteins. Adv Neurobiol 9: 47-70.
    • (2014) Adv Neurobiol , vol.9 , pp. 47-70
    • Bieberich, E.1
  • 18
    • 77949484675 scopus 로고    scopus 로고
    • Arsenic trioxide induces endoplasmic reticulum stress-related events in neutrophils
    • Binet F, Chiasson S, Girard D (2010). Arsenic trioxide induces endoplasmic reticulum stress-related events in neutrophils. Int Immunopharmacol 10: 508-512.
    • (2010) Int Immunopharmacol , vol.10 , pp. 508-512
    • Binet, F.1    Chiasson, S.2    Girard, D.3
  • 19
    • 4844225372 scopus 로고    scopus 로고
    • Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs
    • Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R (2004). Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs. Gastroenterol Clin Biol 28: 720-759.
    • (2004) Gastroenterol Clin Biol , vol.28 , pp. 720-759
    • Biour, M.1    Ben Salem, C.2    Chazouillères, O.3    Grangé, J.D.4    Serfaty, L.5    Poupon, R.6
  • 21
    • 0029094577 scopus 로고
    • Acute renal failure due to acetaminophen ingestion: a case report and review of the literature
    • Blakely P, McDonald BR (1995). Acute renal failure due to acetaminophen ingestion: a case report and review of the literature. J Am Soc Nephrol 6: 48-53.
    • (1995) J Am Soc Nephrol , vol.6 , pp. 48-53
    • Blakely, P.1    McDonald, B.R.2
  • 24
    • 84886455798 scopus 로고    scopus 로고
    • Metabolic effects of the HIV protease inhibitor-saquinavir in differentiating human preadipocytes
    • Bociaga-Jasik M, Polus A, Goralska J, Czech U, Gruca A, Sliwa A, et al. (2013). Metabolic effects of the HIV protease inhibitor-saquinavir in differentiating human preadipocytes. Pharmacol Rep 65: 937-950.
    • (2013) Pharmacol Rep , vol.65 , pp. 937-950
    • Bociaga-Jasik, M.1    Polus, A.2    Goralska, J.3    Czech, U.4    Gruca, A.5    Sliwa, A.6
  • 25
    • 0142219774 scopus 로고    scopus 로고
    • Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity
    • Boelsterli UA (2003). Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity. Toxicol Appl Pharmacol 192: 307-322.
    • (2003) Toxicol Appl Pharmacol , vol.192 , pp. 307-322
    • Boelsterli, U.A.1
  • 26
    • 84873854068 scopus 로고    scopus 로고
    • Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies
    • Boelsterli UA, Redinbo MR, Saitta KS (2013). Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies. Toxicol Sci 131: 654-667.
    • (2013) Toxicol Sci , vol.131 , pp. 654-667
    • Boelsterli, U.A.1    Redinbo, M.R.2    Saitta, K.S.3
  • 28
    • 84863927725 scopus 로고    scopus 로고
    • The human immunodeficiency virus-1 protease inhibitor nelfinavir impairs proteasome activity and inhibits the proliferation of multiple myeloma cells in vitro and in vivo
    • Bono C, Karlin L, Harel S, Mouly E, Labaume S, Galicier L, et al. (2012). The human immunodeficiency virus-1 protease inhibitor nelfinavir impairs proteasome activity and inhibits the proliferation of multiple myeloma cells in vitro and in vivo. Haematologica 97: 1101-1109.
    • (2012) Haematologica , vol.97 , pp. 1101-1109
    • Bono, C.1    Karlin, L.2    Harel, S.3    Mouly, E.4    Labaume, S.5    Galicier, L.6
  • 30
    • 0027604089 scopus 로고
    • Experimental tunicamycin toxicity in cattle, sheep and pigs
    • Bourke CA, Carrigan MJ (1993). Experimental tunicamycin toxicity in cattle, sheep and pigs. Aust Vet J 70: 188-189.
    • (1993) Aust Vet J , vol.70 , pp. 188-189
    • Bourke, C.A.1    Carrigan, M.J.2
  • 31
    • 84860111877 scopus 로고    scopus 로고
    • Arsenic trioxide for management of acute promyelocytic leukemia: current evidence on its role in front-line therapy and recurrent disease
    • Breccia M, Lo-Coco F (2012). Arsenic trioxide for management of acute promyelocytic leukemia: current evidence on its role in front-line therapy and recurrent disease. Expert Opin Pharmacother 13: 1031-1043.
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 1031-1043
    • Breccia, M.1    Lo-Coco, F.2
  • 32
    • 84896715449 scopus 로고    scopus 로고
    • α2-Adrenoceptors are targets for antipsychotic drugs
    • Brosda J, Jantschak F, Pertz HH (2014). α2-Adrenoceptors are targets for antipsychotic drugs. Psychopharmacology 231: 801-812.
    • (2014) Psychopharmacology , vol.231 , pp. 801-812
    • Brosda, J.1    Jantschak, F.2    Pertz, H.H.3
  • 33
    • 79951624230 scopus 로고    scopus 로고
    • Analysis of nelfinavir-induced endoplasmic reticulum stress
    • Brüning A (2011). Analysis of nelfinavir-induced endoplasmic reticulum stress. Methods Enzymol 491: 127-142.
    • (2011) Methods Enzymol , vol.491 , pp. 127-142
    • Brüning, A.1
  • 34
    • 84866849716 scopus 로고    scopus 로고
    • Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4
    • Brüning A, Matsingou C, Brem GJ, Rahmeh M, Mylonas I (2012). Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4. Toxicol Appl Pharmacol 264: 300-304.
    • (2012) Toxicol Appl Pharmacol , vol.264 , pp. 300-304
    • Brüning, A.1    Matsingou, C.2    Brem, G.J.3    Rahmeh, M.4    Mylonas, I.5
  • 35
    • 0023718622 scopus 로고
    • Effect of acetaminophen hepatotoxicity on hepatic mitochondrial and microsomal calcium contents in mice
    • Burcham PC, Harman AW (1988). Effect of acetaminophen hepatotoxicity on hepatic mitochondrial and microsomal calcium contents in mice. Toxicol Lett 44: 91-99.
    • (1988) Toxicol Lett , vol.44 , pp. 91-99
    • Burcham, P.C.1    Harman, A.W.2
  • 36
    • 77954940839 scopus 로고    scopus 로고
    • Prevention of HIV protease inhibitor-induced dysregulation of hepatic lipid metabolism by raltegravir via endoplasmic reticulum stress signaling pathways
    • Cao R, Hu Y, Wang Y, Gurley EC, Studer EJ, Wang X, et al. (2010). Prevention of HIV protease inhibitor-induced dysregulation of hepatic lipid metabolism by raltegravir via endoplasmic reticulum stress signaling pathways. J Pharmacol Exp Ther 334: 530-539.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 530-539
    • Cao, R.1    Hu, Y.2    Wang, Y.3    Gurley, E.C.4    Studer, E.J.5    Wang, X.6
  • 37
    • 84897126655 scopus 로고    scopus 로고
    • 4-Phenylbutyrate inhibits tunicamycin-induced acute kidney injury via CHOP/GADD153 repression
    • Carlisle RE, Brimble E, Werner KE, Cruz GL, Ask K, Ingram AJ, et al. (2014). 4-Phenylbutyrate inhibits tunicamycin-induced acute kidney injury via CHOP/GADD153 repression. PLoS ONE 9: e84663.
    • (2014) PLoS ONE , vol.9
    • Carlisle, R.E.1    Brimble, E.2    Werner, K.E.3    Cruz, G.L.4    Ask, K.5    Ingram, A.J.6
  • 38
    • 34548713556 scopus 로고    scopus 로고
    • Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence
    • Caron M, Auclair M, Donadille B, Béréziat V, Guerci B, Laville M, et al. (2007). Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence. Cell Death Differ 14: 1759-1767.
    • (2007) Cell Death Differ , vol.14 , pp. 1759-1767
    • Caron, M.1    Auclair, M.2    Donadille, B.3    Béréziat, V.4    Guerci, B.5    Laville, M.6
  • 39
    • 78649822338 scopus 로고    scopus 로고
    • Adipose tissue as a target of HIV-1 antiretroviral drugs. Potential consequences on metabolic regulations
    • Caron-Debarle M, Boccara F, Lagathu C, Antoine B, Cervera P, Bastard JP, et al. (2010). Adipose tissue as a target of HIV-1 antiretroviral drugs. Potential consequences on metabolic regulations. Curr Pharm Des 16: 3352-3360.
    • (2010) Curr Pharm Des , vol.16 , pp. 3352-3360
    • Caron-Debarle, M.1    Boccara, F.2    Lagathu, C.3    Antoine, B.4    Cervera, P.5    Bastard, J.P.6
  • 40
    • 84876985996 scopus 로고    scopus 로고
    • Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors
    • Cassol E, Misra V, Holman A, Kamat A, Morgello S, Gabuzda D (2013). Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors. BMC Infect Dis 13: 203.
    • (2013) BMC Infect Dis , vol.13 , pp. 203
    • Cassol, E.1    Misra, V.2    Holman, A.3    Kamat, A.4    Morgello, S.5    Gabuzda, D.6
  • 41
    • 84868621108 scopus 로고    scopus 로고
    • Safety of Non-Steroidal Anti-Inflammatory Drugs (SOS) Project. Individual NSAIDs and upper gastrointestinal complications: a systematic review and meta-analysis of observational studies (the SOS project)
    • Castellsague J, Riera-Guardia N, Calingaert B, Varas-Lorenzo C, Fourrier-Reglat A, Nicotra F, et al. (2012). Safety of Non-Steroidal Anti-Inflammatory Drugs (SOS) Project. Individual NSAIDs and upper gastrointestinal complications: a systematic review and meta-analysis of observational studies (the SOS project). Drug Saf 35: 1127-1146.
    • (2012) Drug Saf , vol.35 , pp. 1127-1146
    • Castellsague, J.1    Riera-Guardia, N.2    Calingaert, B.3    Varas-Lorenzo, C.4    Fourrier-Reglat, A.5    Nicotra, F.6
  • 42
    • 79251508006 scopus 로고    scopus 로고
    • Assays for detecting the unfolded protein response
    • Cawley K, Deegan S, Samali A, Gupta S (2011). Assays for detecting the unfolded protein response. Methods Enzymol 490: 31-51.
    • (2011) Methods Enzymol , vol.490 , pp. 31-51
    • Cawley, K.1    Deegan, S.2    Samali, A.3    Gupta, S.4
  • 43
    • 0029935762 scopus 로고    scopus 로고
    • Specific toxicity of tunicamycin in induction of programmed cell death of sympathetic neurons
    • Chang JY, Korolev VV (1996). Specific toxicity of tunicamycin in induction of programmed cell death of sympathetic neurons. Exp Neurol 137: 201-211.
    • (1996) Exp Neurol , vol.137 , pp. 201-211
    • Chang, J.Y.1    Korolev, V.V.2
  • 44
    • 13444257678 scopus 로고    scopus 로고
    • Bleomycins: towards better therapeutics
    • Chen J, Stubbe J (2005). Bleomycins: towards better therapeutics. Nat Rev Cancer 5: 102-112.
    • (2005) Nat Rev Cancer , vol.5 , pp. 102-112
    • Chen, J.1    Stubbe, J.2
  • 45
    • 84868210879 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress contributes to arsenic trioxide-induced apoptosis in drug-sensitive and -resistant leukemia cells
    • Chen J, Wei H, Xie B, Wang B, Cheng J, Cheng J (2012). Endoplasmic reticulum stress contributes to arsenic trioxide-induced apoptosis in drug-sensitive and -resistant leukemia cells. Leuk Res 36: 1526-1535.
    • (2012) Leuk Res , vol.36 , pp. 1526-1535
    • Chen, J.1    Wei, H.2    Xie, B.3    Wang, B.4    Cheng, J.5    Cheng, J.6
  • 47
    • 84945939091 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis
    • Chen B, Liu G, Zou P, Li X, Hao Q, Jiang B, et al. (2015). Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis. Exp Biol Med 240: 1513-1519.
    • (2015) Exp Biol Med , vol.240 , pp. 1513-1519
    • Chen, B.1    Liu, G.2    Zou, P.3    Li, X.4    Hao, Q.5    Jiang, B.6
  • 48
    • 84884769320 scopus 로고    scopus 로고
    • Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases
    • Cheng B, Gong H, Xiao H, Petersen RB, Zheng L, Huang K (2013). Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases. Biochim Biophys Acta 1830: 4860-4871.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 4860-4871
    • Cheng, B.1    Gong, H.2    Xiao, H.3    Petersen, R.B.4    Zheng, L.5    Huang, K.6
  • 49
    • 84873662942 scopus 로고    scopus 로고
    • C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver
    • Chikka MR, McCabe DD, Tyra HM, Rutkowski DT (2013). C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver. J Biol Chem 288: 4405-4415.
    • (2013) J Biol Chem , vol.288 , pp. 4405-4415
    • Chikka, M.R.1    McCabe, D.D.2    Tyra, H.M.3    Rutkowski, D.T.4
  • 50
    • 84919483390 scopus 로고    scopus 로고
    • Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin-proteasome system in human sarcoma cells
    • Chiu HW, Tseng YC, Hsu YH, Lin YF, Foo NP, Guo HR, et al. (2015). Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin-proteasome system in human sarcoma cells. Cancer Lett 356: 762-772.
    • (2015) Cancer Lett , vol.356 , pp. 762-772
    • Chiu, H.W.1    Tseng, Y.C.2    Hsu, Y.H.3    Lin, Y.F.4    Foo, N.P.5    Guo, H.R.6
  • 51
    • 0028863807 scopus 로고
    • Alternative cyclosporine metabolic pathways and toxicity
    • Christians U, Sewing KF (1995). Alternative cyclosporine metabolic pathways and toxicity. Clin Biochem 28: 547-559.
    • (1995) Clin Biochem , vol.28 , pp. 547-559
    • Christians, U.1    Sewing, K.F.2
  • 52
    • 84855605795 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress, obesity and diabetes
    • Cnop M, Foufelle F, Velloso LA (2012). Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med 18: 59-68.
    • (2012) Trends Mol Med , vol.18 , pp. 59-68
    • Cnop, M.1    Foufelle, F.2    Velloso, L.A.3
  • 53
    • 77149136381 scopus 로고    scopus 로고
    • Calcium binding chaperones of the endoplasmic reticulum
    • Coe H, Michalak M (2009). Calcium binding chaperones of the endoplasmic reticulum. Gen Physiol Biophys 28: F96-F103.
    • (2009) Gen Physiol Biophys , vol.28 , pp. F96-F103
    • Coe, H.1    Michalak, M.2
  • 54
    • 34548220998 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2
    • Colgan SM, Tang D, Werstuck GH, Austin RC (2007). Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. Int J Biochem Cell Biol 39: 1843-1851.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1843-1851
    • Colgan, S.M.1    Tang, D.2    Werstuck, G.H.3    Austin, R.C.4
  • 56
    • 33749022800 scopus 로고    scopus 로고
    • Structural and functional features and significance of the physical linkage between ER and mitochondria
    • Csordas G, Renken C, Varnai P, Walter L, Weaver D, Buttle KF, et al. (2006). Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol 174: 915-921.
    • (2006) J Cell Biol , vol.174 , pp. 915-921
    • Csordas, G.1    Renken, C.2    Varnai, P.3    Walter, L.4    Weaver, D.5    Buttle, K.F.6
  • 57
    • 77954301751 scopus 로고    scopus 로고
    • Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface
    • Csordas G, Varnai P, Golenar T, Roy S, Purkins G, Schneider TG, et al. (2010). Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface. Mol Cell 39: 121-132.
    • (2010) Mol Cell , vol.39 , pp. 121-132
    • Csordas, G.1    Varnai, P.2    Golenar, T.3    Roy, S.4    Purkins, G.5    Schneider, T.G.6
  • 58
    • 29244462498 scopus 로고    scopus 로고
    • Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway
    • Cullinan SB, Diehl JA (2006). Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol 38: 317-332.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 317-332
    • Cullinan, S.B.1    Diehl, J.A.2
  • 59
    • 79955601004 scopus 로고    scopus 로고
    • Drug-induced autoimmune-like hepatitis
    • Czaja AJ (2011). Drug-induced autoimmune-like hepatitis. Dig Dis Sci 56: 958-976.
    • (2011) Dig Dis Sci , vol.56 , pp. 958-976
    • Czaja, A.J.1
  • 60
    • 79955103141 scopus 로고    scopus 로고
    • The contribution of endoplasmic reticulum stress to liver diseases
    • Dara L, Ji C, Kaplowitz N (2011). The contribution of endoplasmic reticulum stress to liver diseases. Hepatology 53: 1752-1763.
    • (2011) Hepatology , vol.53 , pp. 1752-1763
    • Dara, L.1    Ji, C.2    Kaplowitz, N.3
  • 61
    • 77949503909 scopus 로고    scopus 로고
    • Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
    • Das J, Ghosh J, Manna P, Sil PC (2010). Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation. Toxicology 269: 24-34.
    • (2010) Toxicology , vol.269 , pp. 24-34
    • Das, J.1    Ghosh, J.2    Manna, P.3    Sil, P.C.4
  • 62
    • 84906544769 scopus 로고    scopus 로고
    • Cisplatin in cancer therapy: molecular mechanisms of action
    • Dasari S, Tchounwou PB (2014). Cisplatin in cancer therapy: molecular mechanisms of action. Eur J Pharmacol 740: 364-378.
    • (2014) Eur J Pharmacol , vol.740 , pp. 364-378
    • Dasari, S.1    Tchounwou, P.B.2
  • 63
    • 84455171488 scopus 로고    scopus 로고
    • In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans
    • Dawson S, Stahl S, Paul N, Barber J, Kenna JG (2012). In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug Metab Dispos 40: 130-138.
    • (2012) Drug Metab Dispos , vol.40 , pp. 130-138
    • Dawson, S.1    Stahl, S.2    Paul, N.3    Barber, J.4    Kenna, J.G.5
  • 66
    • 84930678119 scopus 로고    scopus 로고
    • Bleomycin in the setting of lung fibrosis induction: From biological mechanisms to counteractions
    • Della Latta V, Cecchettini A, Del Ry S, Morales MA (2015). Bleomycin in the setting of lung fibrosis induction: From biological mechanisms to counteractions. Pharmacol Res 97: 122-130.
    • (2015) Pharmacol Res , vol.97 , pp. 122-130
    • Della Latta, V.1    Cecchettini, A.2    Del Ry, S.3    Morales, M.A.4
  • 67
    • 38049155818 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
    • Deniaud A, Sharaf el dein O, Maillier E, Poncet D, Kroemer G, Lemaire C, et al. (2008) Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene27:285-299.
    • (2008) Oncogene , vol.27 , pp. 285-299
    • Deniaud, A.1    el dein Sharaf, O.2    Maillier, E.3    Poncet, D.4    Kroemer, G.5    Lemaire, C.6
  • 68
    • 24644432531 scopus 로고    scopus 로고
    • The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer
    • Denmeade SR, Isaacs JT (2005). The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer. Cancer Biol Ther 4: 14-22.
    • (2005) Cancer Biol Ther , vol.4 , pp. 14-22
    • Denmeade, S.R.1    Isaacs, J.T.2
  • 69
    • 0034527664 scopus 로고    scopus 로고
    • Amiodarone induces cytochrome c release and apoptosis through an iodine-independent mechanism
    • Di Matola T, D'Ascoli F, Fenzi G, Rossi G, Martino E, Bogazzi F, et al. (2000). Amiodarone induces cytochrome c release and apoptosis through an iodine-independent mechanism. J Clin Endocrinol Metab 85: 4323-4330.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4323-4330
    • Di Matola, T.1    D'Ascoli, F.2    Fenzi, G.3    Rossi, G.4    Martino, E.5    Bogazzi, F.6
  • 70
    • 84889889353 scopus 로고    scopus 로고
    • Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy
    • Digaleh H, Kiaei M, Khodagholi F (2013). Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy. Cell Mol Life Sci 70: 4681-4694.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 4681-4694
    • Digaleh, H.1    Kiaei, M.2    Khodagholi, F.3
  • 71
    • 0037478407 scopus 로고    scopus 로고
    • Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts
    • Ding X, Kaminsky LS (2003). Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol 43: 149-173.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 149-173
    • Ding, X.1    Kaminsky, L.S.2
  • 73
    • 84907362479 scopus 로고    scopus 로고
    • Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system
    • Dou QP, Zonder JA (2014). Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system. Curr Cancer Drug Targets 14: 517-536.
    • (2014) Curr Cancer Drug Targets , vol.14 , pp. 517-536
    • Dou, Q.P.1    Zonder, J.A.2
  • 74
    • 17144377127 scopus 로고    scopus 로고
    • Arsenic trioxide: new clinical experience with an old medication in hematologic malignancies
    • Douer D, Tallman MS (2005). Arsenic trioxide: new clinical experience with an old medication in hematologic malignancies. J Clin Oncol 23: 2396-2410.
    • (2005) J Clin Oncol , vol.23 , pp. 2396-2410
    • Douer, D.1    Tallman, M.S.2
  • 75
    • 32644449422 scopus 로고    scopus 로고
    • Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia
    • Du Y, Wang K, Fang H, Li J, Xiao D, Zheng P, et al. (2006). Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia. Blood 107: 1582-1590.
    • (2006) Blood , vol.107 , pp. 1582-1590
    • Du, Y.1    Wang, K.2    Fang, H.3    Li, J.4    Xiao, D.5    Zheng, P.6
  • 76
    • 84886095138 scopus 로고    scopus 로고
    • Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: complex regulation by intracellular calcium
    • Dubois C, Vanden Abeele F, Sehgal P, Olesen C, Junker S, Christensen SB, et al. (2013). Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: complex regulation by intracellular calcium. FEBS J 280: 5430-5440.
    • (2013) FEBS J , vol.280 , pp. 5430-5440
    • Dubois, C.1    Vanden Abeele, F.2    Sehgal, P.3    Olesen, C.4    Junker, S.5    Christensen, S.B.6
  • 78
    • 67649392372 scopus 로고    scopus 로고
    • Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function
    • Dutheil F, Dauchy S, Diry M, Sazdovitch V, Cloarec O, Mellottée L, et al. (2009). Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function. Drug Metab Dispos 37: 1528-1538.
    • (2009) Drug Metab Dispos , vol.37 , pp. 1528-1538
    • Dutheil, F.1    Dauchy, S.2    Diry, M.3    Sazdovitch, V.4    Cloarec, O.5    Mellottée, L.6
  • 80
    • 78649922972 scopus 로고    scopus 로고
    • Drug-induced valvulopathy: an update
    • Elangbam CS (2010). Drug-induced valvulopathy: an update. Toxicol Pathol 38: 837-848.
    • (2010) Toxicol Pathol , vol.38 , pp. 837-848
    • Elangbam, C.S.1
  • 81
    • 0000943174 scopus 로고
    • The tunicamycins: useful tools for studies on glycoproteins
    • Elbein AD (1981). The tunicamycins: useful tools for studies on glycoproteins. Trends Biochem Sci 6: 219-221.
    • (1981) Trends Biochem Sci , vol.6 , pp. 219-221
    • Elbein, A.D.1
  • 82
    • 77950295405 scopus 로고    scopus 로고
    • Xenobiotic-metabolizing cytochromes P450 in human white adipose tissue: expression and induction
    • Ellero S, Chakhtoura G, Barreau C, Langouët S, Benelli C, Penicaud L, et al. (2010). Xenobiotic-metabolizing cytochromes P450 in human white adipose tissue: expression and induction. Drug Metab Dispos 38: 679-686.
    • (2010) Drug Metab Dispos , vol.38 , pp. 679-686
    • Ellero, S.1    Chakhtoura, G.2    Barreau, C.3    Langouët, S.4    Benelli, C.5    Penicaud, L.6
  • 84
    • 0023370667 scopus 로고
    • Cyclosporine-induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function
    • English J, Evan A, Houghton DC, Bennett WM (1987). Cyclosporine-induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function. Transplantation 44: 135-141.
    • (1987) Transplantation , vol.44 , pp. 135-141
    • English, J.1    Evan, A.2    Houghton, D.C.3    Bennett, W.M.4
  • 85
    • 0017707408 scopus 로고
    • Tunicamycin inhibits GlcNAc-lipid formation in plants
    • Ericson MC, Gafford JT, Elbein AD (1977). Tunicamycin inhibits GlcNAc-lipid formation in plants. J Biol Chem 252: 7431-7433.
    • (1977) J Biol Chem , vol.252 , pp. 7431-7433
    • Ericson, M.C.1    Gafford, J.T.2    Elbein, A.D.3
  • 86
    • 84899819944 scopus 로고    scopus 로고
    • Erlotinib promotes endoplasmic reticulum stress-mediated injury in the intestinal epithelium
    • Fan L, Hu L, Yang B, Fang X, Gao Z, Li W, et al. (2014). Erlotinib promotes endoplasmic reticulum stress-mediated injury in the intestinal epithelium. Toxicol Appl Pharmacol 278: 45-52.
    • (2014) Toxicol Appl Pharmacol , vol.278 , pp. 45-52
    • Fan, L.1    Hu, L.2    Yang, B.3    Fang, X.4    Gao, Z.5    Li, W.6
  • 87
    • 0023930263 scopus 로고
    • Pathological and pathogenetic changes in the central nervous system of guinea pigs given tunicamycin
    • Finnie JW, O'Shea JD (1988). Pathological and pathogenetic changes in the central nervous system of guinea pigs given tunicamycin. Acta Neuropathol 75: 411-421.
    • (1988) Acta Neuropathol , vol.75 , pp. 411-421
    • Finnie, J.W.1    O'Shea, J.D.2
  • 88
    • 0024801917 scopus 로고
    • Acute hepatotoxicity with resultant pulmonary and cerebral embolism in guinea pigs given tunicamycin
    • Finnie JW, O'Shea JD (1989). Acute hepatotoxicity with resultant pulmonary and cerebral embolism in guinea pigs given tunicamycin. Pathology 21: 194-199.
    • (1989) Pathology , vol.21 , pp. 194-199
    • Finnie, J.W.1    O'Shea, J.D.2
  • 89
    • 0025300710 scopus 로고
    • Effect of tunicamycin on the blood-brain barrier and on endothelial cells in vitro
    • Finnie JW, O'Shea JD (1990a). Effect of tunicamycin on the blood-brain barrier and on endothelial cells in vitro. J Comp Pathol 102: 363-374.
    • (1990) J Comp Pathol , vol.102 , pp. 363-374
    • Finnie, J.W.1    O'Shea, J.D.2
  • 90
    • 0025126591 scopus 로고
    • Unusual concretions in the hepatocyte rough endoplasmic reticulum of sheep given tunicamycin
    • Finnie JW, O'Shea JD (1990b). Unusual concretions in the hepatocyte rough endoplasmic reticulum of sheep given tunicamycin. J Comp Pathol 103: 121-123.
    • (1990) J Comp Pathol , vol.103 , pp. 121-123
    • Finnie, J.W.1    O'Shea, J.D.2
  • 91
    • 2342617454 scopus 로고    scopus 로고
    • Apoptosis in liver damage produced by tunicamycin
    • Finnie JW, Read SH, Swift JG (2004). Apoptosis in liver damage produced by tunicamycin. Aust Vet J 82: 87-90.
    • (2004) Aust Vet J , vol.82 , pp. 87-90
    • Finnie, J.W.1    Read, S.H.2    Swift, J.G.3
  • 93
    • 79953700297 scopus 로고    scopus 로고
    • Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects
    • Florea AM, Büsselberg D (2011). Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects. Cancers 3: 1351-1371.
    • (2011) Cancers , vol.3 , pp. 1351-1371
    • Florea, A.M.1    Büsselberg, D.2
  • 94
    • 84883780939 scopus 로고    scopus 로고
    • Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells
    • Fonseca AC, Ferreiro E, Oliveira CR, Cardoso SM, Pereira CF (2013). Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells. Biochim Biophys Acta 1832: 2191-2203.
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 2191-2203
    • Fonseca, A.C.1    Ferreiro, E.2    Oliveira, C.R.3    Cardoso, S.M.4    Pereira, C.F.5
  • 95
    • 80053441126 scopus 로고    scopus 로고
    • In the Huh7 Hepatoma Cells Diclofenac and indomethacin activate differently the unfolded protein response and induce ER stress apoptosis
    • Franceschelli S, Moltedo O, Amodio G, Tajana G, Remondelli P (2011). In the Huh7 Hepatoma Cells Diclofenac and indomethacin activate differently the unfolded protein response and induce ER stress apoptosis. Open Biochem J 5: 45-51.
    • (2011) Open Biochem J , vol.5 , pp. 45-51
    • Franceschelli, S.1    Moltedo, O.2    Amodio, G.3    Tajana, G.4    Remondelli, P.5
  • 96
    • 84903837546 scopus 로고    scopus 로고
    • Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity
    • Fredriksson L, Wink S, Herpers B, Benedetti G, Hadi M, de Bont H, et al. (2014). Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity. Toxicol Sci 140: 144-159.
    • (2014) Toxicol Sci , vol.140 , pp. 144-159
    • Fredriksson, L.1    Wink, S.2    Herpers, B.3    Benedetti, G.4    Hadi, M.5    de Bont, H.6
  • 97
    • 33751189389 scopus 로고    scopus 로고
    • Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress
    • Fribley A, Wang CY (2006). Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress. Cancer Biol Ther 5: 745-748.
    • (2006) Cancer Biol Ther , vol.5 , pp. 745-748
    • Fribley, A.1    Wang, C.Y.2
  • 98
    • 7644242953 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells
    • Fribley A, Zeng Q, Wang CY (2004). Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol Cell Biol 24: 9695-9704.
    • (2004) Mol Cell Biol , vol.24 , pp. 9695-9704
    • Fribley, A.1    Zeng, Q.2    Wang, C.Y.3
  • 99
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
    • Fromenty B, Pessayre D (1995). Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity. Pharmacol Ther 67: 101-154.
    • (1995) Pharmacol Ther , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 102
    • 78650412221 scopus 로고    scopus 로고
    • Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA
    • Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP (2010). Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci 30: 16938-16948.
    • (2010) J Neurosci , vol.30 , pp. 16938-16948
    • Galehdar, Z.1    Swan, P.2    Fuerth, B.3    Callaghan, S.M.4    Park, D.S.5    Cregan, S.P.6
  • 103
    • 84893865137 scopus 로고    scopus 로고
    • Grape seed proanthocyanidin extract protects from cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis
    • Gao Z, Liu G, Hu Z, Li X, Yang X, Jiang B, et al. (2014). Grape seed proanthocyanidin extract protects from cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis. Mol Med Rep 9: 801-807.
    • (2014) Mol Med Rep , vol.9 , pp. 801-807
    • Gao, Z.1    Liu, G.2    Hu, Z.3    Li, X.4    Yang, X.5    Jiang, B.6
  • 107
    • 33845953191 scopus 로고    scopus 로고
    • The 2006 Bernard B. Brodie Award Lecture. Cyp2E1
    • Gonzalez FJ (2007). The 2006 Bernard B. Brodie Award Lecture. Cyp2E1. Drug Metab Dispos 35: 1-8.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1-8
    • Gonzalez, F.J.1
  • 108
    • 61649108800 scopus 로고    scopus 로고
    • A child presenting with acute renal failure secondary to a high dose of indomethacin: a case report
    • Gonzalez F, Lopez-Herce J, Moraleda C (2009). A child presenting with acute renal failure secondary to a high dose of indomethacin: a case report. J Med Case Rep 3: 47.
    • (2009) J Med Case Rep , vol.3 , pp. 47
    • Gonzalez, F.1    Lopez-Herce, J.2    Moraleda, C.3
  • 109
    • 84886583599 scopus 로고    scopus 로고
    • The paradox of paclitaxel neurotoxicity: Mechanisms and unanswered questions
    • Gornstein E, Schwarz TL (2014). The paradox of paclitaxel neurotoxicity: Mechanisms and unanswered questions. Neuropharmacology 76: 175-183.
    • (2014) Neuropharmacology , vol.76 , pp. 175-183
    • Gornstein, E.1    Schwarz, T.L.2
  • 110
    • 2342441342 scopus 로고    scopus 로고
    • Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations
    • Gougeon ML, Pénicaud L, Fromenty B, Leclercq P, Viard JP, Capeau J (2004). Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations. Antivir Ther 9: 161-177.
    • (2004) Antivir Ther , vol.9 , pp. 161-177
    • Gougeon, M.L.1    Pénicaud, L.2    Fromenty, B.3    Leclercq, P.4    Viard, J.P.5    Capeau, J.6
  • 111
    • 0027933909 scopus 로고
    • Cyclosporine: mechanisms of action and toxicity
    • Graham RM (1994). Cyclosporine: mechanisms of action and toxicity. Cleve Clin J Med 61: 308-313.
    • (1994) Cleve Clin J Med , vol.61 , pp. 308-313
    • Graham, R.M.1
  • 112
    • 0027412278 scopus 로고
    • The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition
    • Grieve EM, Hawksworth GM, Simpson JG, Whiting PH (1993). The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition. Biochem Pharmacol 45: 1351-1354.
    • (1993) Biochem Pharmacol , vol.45 , pp. 1351-1354
    • Grieve, E.M.1    Hawksworth, G.M.2    Simpson, J.G.3    Whiting, P.H.4
  • 113
    • 14944339649 scopus 로고    scopus 로고
    • In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa
    • Gu J, Cui H, Behr M, Zhang L, Zhang QY, Yang W, et al. (2005). In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa. Mol Pharmacol 67: 623-630.
    • (2005) Mol Pharmacol , vol.67 , pp. 623-630
    • Gu, J.1    Cui, H.2    Behr, M.3    Zhang, L.4    Zhang, Q.Y.5    Yang, W.6
  • 114
    • 34247265390 scopus 로고    scopus 로고
    • The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response
    • Gupta AK, Li B, Cerniglia GJ, Ahmed MS, Hahn SM, Maity A (2007). The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response. Neoplasia 9: 271-278.
    • (2007) Neoplasia , vol.9 , pp. 271-278
    • Gupta, A.K.1    Li, B.2    Cerniglia, G.J.3    Ahmed, M.S.4    Hahn, S.M.5    Maity, A.6
  • 115
    • 84866696407 scopus 로고    scopus 로고
    • Worsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective study
    • Gupta SK, Shen C, Moe SM, Kamendulis LM, Goldman M, Dubé MP (2012). Worsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective study. PLoS ONE 7: e45716.
    • (2012) PLoS ONE , vol.7
    • Gupta, S.K.1    Shen, C.2    Moe, S.M.3    Kamendulis, L.M.4    Goldman, M.5    Dubé, M.P.6
  • 116
    • 0033909952 scopus 로고    scopus 로고
    • Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice
    • Hagiwara SI, Ishii Y, Kitamura S (2000). Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice. Am J Respir Crit Care Med 162: 225-231.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 225-231
    • Hagiwara, S.I.1    Ishii, Y.2    Kitamura, S.3
  • 117
    • 65549108291 scopus 로고    scopus 로고
    • Protective effect of N-acetylcysteine on cyclosporine A-induced lipid peroxide levels and renal dysfunction in rats
    • Haleagrahara N, Yee TM, Chakravarthi S, Lee N (2009). Protective effect of N-acetylcysteine on cyclosporine A-induced lipid peroxide levels and renal dysfunction in rats. Arch Med Sci 1: 16-22.
    • (2009) Arch Med Sci , vol.1 , pp. 16-22
    • Haleagrahara, N.1    Yee, T.M.2    Chakravarthi, S.3    Lee, N.4
  • 118
    • 84902544937 scopus 로고    scopus 로고
    • The many functions of the endoplasmic reticulum chaperones and folding enzymes
    • Halperin L, Jung J, Michalak M (2014). The many functions of the endoplasmic reticulum chaperones and folding enzymes. IUBMB Life 66: 318-326.
    • (2014) IUBMB Life , vol.66 , pp. 318-326
    • Halperin, L.1    Jung, J.2    Michalak, M.3
  • 119
    • 84880572838 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress with low-dose cyclosporine in frequently relapsing nephrotic syndrome
    • Hama T, Nakanishi K, Mukaiyama H, Shima Y, Togawa H, Sako M, et al. (2013). Endoplasmic reticulum stress with low-dose cyclosporine in frequently relapsing nephrotic syndrome. Pediatr Nephrol 28: 903-909.
    • (2013) Pediatr Nephrol , vol.28 , pp. 903-909
    • Hama, T.1    Nakanishi, K.2    Mukaiyama, H.3    Shima, Y.4    Togawa, H.5    Sako, M.6
  • 121
    • 51149116786 scopus 로고    scopus 로고
    • Prolonged endoplasmic reticulum stress induces apoptotic cell death in an experimental model of chronic cyclosporine nephropathy
    • Han SW, Li C, Ahn KO, Lim SW, Song HG, Jang YS, et al. (2008). Prolonged endoplasmic reticulum stress induces apoptotic cell death in an experimental model of chronic cyclosporine nephropathy. Am J Nephrol 28: 707-714.
    • (2008) Am J Nephrol , vol.28 , pp. 707-714
    • Han, S.W.1    Li, C.2    Ahn, K.O.3    Lim, S.W.4    Song, H.G.5    Jang, Y.S.6
  • 122
    • 0028815559 scopus 로고
    • Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac
    • Hargus SJ, Martin BM, George JW, Pohl LR (1995). Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac. Chem Res Toxicol 8: 993-996.
    • (1995) Chem Res Toxicol , vol.8 , pp. 993-996
    • Hargus, S.J.1    Martin, B.M.2    George, J.W.3    Pohl, L.R.4
  • 123
    • 0028285701 scopus 로고
    • Acetaminophen nephrotoxicity in CD-1 mice. I. Evidence of a role for in situ activation in selective covalent binding and toxicity
    • Hart SG, Beierschmitt WP, Wyand DS, Khairallah EA, Cohen SD (1994). Acetaminophen nephrotoxicity in CD-1 mice. I. Evidence of a role for in situ activation in selective covalent binding and toxicity. Toxicol Appl Pharmacol 126: 267-275.
    • (1994) Toxicol Appl Pharmacol , vol.126 , pp. 267-275
    • Hart, S.G.1    Beierschmitt, W.P.2    Wyand, D.S.3    Khairallah, E.A.4    Cohen, S.D.5
  • 125
    • 0033980083 scopus 로고    scopus 로고
    • Bleomycin: new perspectives on the mechanism of action
    • Hecht SM (2000). Bleomycin: new perspectives on the mechanism of action. J Nat Prod 63: 158-168.
    • (2000) J Nat Prod , vol.63 , pp. 158-168
    • Hecht, S.M.1
  • 126
    • 0017646948 scopus 로고
    • Studies of the mechanism of tunicamycin inhibition of IgA and IgE secretion by plasma cells
    • Hickman S, Kulczycki A Jr, Lynch RG, Kornfeld S (1977). Studies of the mechanism of tunicamycin inhibition of IgA and IgE secretion by plasma cells. J Biol Chem 252: 4402-4408.
    • (1977) J Biol Chem , vol.252 , pp. 4402-4408
    • Hickman, S.1    Kulczycki, A.2    Lynch, R.G.3    Kornfeld, S.4
  • 127
    • 79951648063 scopus 로고    scopus 로고
    • Monitoring and manipulating mammalian unfolded protein response
    • Hiramatsu N, Joseph VT, Lin JH (2011). Monitoring and manipulating mammalian unfolded protein response. Methods Enzymol 491: 183-198.
    • (2011) Methods Enzymol , vol.491 , pp. 183-198
    • Hiramatsu, N.1    Joseph, V.T.2    Lin, J.H.3
  • 128
    • 84904723697 scopus 로고    scopus 로고
    • Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity
    • van den Hof WF, Van Summeren A, Lommen A, Coonen ML, Brauers K, van Herwijnen M, et al. (2014). Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity. Toxicology 324: 18-26.
    • (2014) Toxicology , vol.324 , pp. 18-26
    • van den Hof, W.F.1    Van Summeren, A.2    Lommen, A.3    Coonen, M.L.4    Brauers, K.5    van Herwijnen, M.6
  • 129
    • 84862290919 scopus 로고    scopus 로고
    • Drug induced rhabdomyolysis
    • Hohenegger M (2012). Drug induced rhabdomyolysis. Curr Opin Pharmacol 12: 335-339.
    • (2012) Curr Opin Pharmacol , vol.12 , pp. 335-339
    • Hohenegger, M.1
  • 130
    • 84862215014 scopus 로고    scopus 로고
    • Proteasome inhibitors in mantle cell lymphoma
    • Holkova B, Grant S (2012). Proteasome inhibitors in mantle cell lymphoma. Best Pract Res Clin Haematol 25: 133-141.
    • (2012) Best Pract Res Clin Haematol , vol.25 , pp. 133-141
    • Holkova, B.1    Grant, S.2
  • 131
    • 34347386472 scopus 로고    scopus 로고
    • Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis
    • Hom JR, Gewandter JS, Michael L, Sheu SS, Yoon Y (2007). Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis. J Cell Physiol 212: 498-508.
    • (2007) J Cell Physiol , vol.212 , pp. 498-508
    • Hom, J.R.1    Gewandter, J.S.2    Michael, L.3    Sheu, S.S.4    Yoon, Y.5
  • 132
    • 34548037901 scopus 로고    scopus 로고
    • Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
    • Hoyer-Hansen M, Jäättelä M (2007). Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ 14: 1576-1582.
    • (2007) Cell Death Differ , vol.14 , pp. 1576-1582
    • Hoyer-Hansen, M.1    Jäättelä, M.2
  • 133
    • 84921455623 scopus 로고    scopus 로고
    • Effects of combined alcohol and anti-HIV drugs on cellular stress responses in primary hepatocytes and hepatic stellate and Kupffer cells
    • Hu J, Han H, Lau MY, Lee H, MacVeigh-Aloni M, Ji C (2015). Effects of combined alcohol and anti-HIV drugs on cellular stress responses in primary hepatocytes and hepatic stellate and Kupffer cells. Alcohol Clin Exp Res 39: 11-20.
    • (2015) Alcohol Clin Exp Res , vol.39 , pp. 11-20
    • Hu, J.1    Han, H.2    Lau, M.Y.3    Lee, H.4    MacVeigh-Aloni, M.5    Ji, C.6
  • 134
    • 0037036578 scopus 로고    scopus 로고
    • Arsenic toxicity and potential mechanisms of action
    • Hughes MF (2002). Arsenic toxicity and potential mechanisms of action. Toxicol Lett 133: 1-16.
    • (2002) Toxicol Lett , vol.133 , pp. 1-16
    • Hughes, M.F.1
  • 137
    • 80052712639 scopus 로고    scopus 로고
    • Clinical and experimental applications of sodium phenylbutyrate
    • Iannitti T, Palmieri B (2011). Clinical and experimental applications of sodium phenylbutyrate. Drugs RD 11: 227-249.
    • (2011) Drugs RD , vol.11 , pp. 227-249
    • Iannitti, T.1    Palmieri, B.2
  • 138
    • 33745854202 scopus 로고    scopus 로고
    • Mitochondrial, metabolic and genotoxic effects of antiretroviral nucleoside reverse-transcriptase Inhibitors
    • Igoudjil A, Begriche K, Pessayre D, Fromenty B (2006). Mitochondrial, metabolic and genotoxic effects of antiretroviral nucleoside reverse-transcriptase Inhibitors. AntiInfect Agents Med Chem 5: 273-292.
    • (2006) AntiInfect Agents Med Chem , vol.5 , pp. 273-292
    • Igoudjil, A.1    Begriche, K.2    Pessayre, D.3    Fromenty, B.4
  • 139
    • 84903532662 scopus 로고    scopus 로고
    • Proteostasis in endoplasmic reticulum- new mechanisms in kidney disease
    • Inagi R, Ishimoto Y, Nangaku M (2014). Proteostasis in endoplasmic reticulum- new mechanisms in kidney disease. Nat Rev Nephrol 10: 369-378.
    • (2014) Nat Rev Nephrol , vol.10 , pp. 369-378
    • Inagi, R.1    Ishimoto, Y.2    Nangaku, M.3
  • 140
    • 29944444428 scopus 로고    scopus 로고
    • New strategies for the medical treatment of prostate cancer
    • Isaacs JT (2005). New strategies for the medical treatment of prostate cancer. BJU Int 96: 35-40.
    • (2005) BJU Int , vol.96 , pp. 35-40
    • Isaacs, J.T.1
  • 142
  • 143
  • 144
    • 84872241449 scopus 로고    scopus 로고
    • Arsenite interferes with protein folding and triggers formation of protein aggregates in yeast
    • Jacobson T, Navarrete C, Sharma SK, Sideri TC, Ibstedt S, Priya S, et al. (2012). Arsenite interferes with protein folding and triggers formation of protein aggregates in yeast. J Cell Sci 125: 5073-5083.
    • (2012) J Cell Sci , vol.125 , pp. 5073-5083
    • Jacobson, T.1    Navarrete, C.2    Sharma, S.K.3    Sideri, T.C.4    Ibstedt, S.5    Priya, S.6
  • 145
    • 0025673837 scopus 로고
    • Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol
    • Jaeschke H (1990). Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol. J Pharmacol Exp Ther 255: 935-941.
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 935-941
    • Jaeschke, H.1
  • 146
    • 84855892790 scopus 로고    scopus 로고
    • Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity
    • Jaeschke H, McGill MR, Ramachandran A (2012). Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity. Drug Metab Rev 44: 88-106.
    • (2012) Drug Metab Rev , vol.44 , pp. 88-106
    • Jaeschke, H.1    McGill, M.R.2    Ramachandran, A.3
  • 148
    • 84876154662 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor
    • Jo H, Choe SS, Shin KC, Jang H, Lee JH, Seong JK, et al. (2013). Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor. Hepatology 57: 1366-1377.
    • (2013) Hepatology , vol.57 , pp. 1366-1377
    • Jo, H.1    Choe, S.S.2    Shin, K.C.3    Jang, H.4    Lee, J.H.5    Seong, J.K.6
  • 149
    • 67649159093 scopus 로고    scopus 로고
    • Renal toxicity of therapeutic drugs
    • John R, Herzenberg AM (2009). Renal toxicity of therapeutic drugs. J Clin Pathol 62: 505-515.
    • (2009) J Clin Pathol , vol.62 , pp. 505-515
    • John, R.1    Herzenberg, A.M.2
  • 151
    • 0030952977 scopus 로고    scopus 로고
    • Unusual complications of paracetamol poisoning
    • Jones AL, Prescott LF (1997). Unusual complications of paracetamol poisoning. QJM 90: 161-168.
    • (1997) QJM , vol.90 , pp. 161-168
    • Jones, A.L.1    Prescott, L.F.2
  • 153
    • 0037323992 scopus 로고    scopus 로고
    • Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimus
    • Jorgensen KA, Koefoed-Nielsen PB, Karamperis N (2003). Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimus. Scand J Immunol 57: 93-98.
    • (2003) Scand J Immunol , vol.57 , pp. 93-98
    • Jorgensen, K.A.1    Koefoed-Nielsen, P.B.2    Karamperis, N.3
  • 154
    • 84900022147 scopus 로고    scopus 로고
    • Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways
    • Kalinec GM, Thein P, Parsa A, Yorgason J, Luxford W, Urrutia R, et al. (2014). Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways. Hear Res 313: 26-37.
    • (2014) Hear Res , vol.313 , pp. 26-37
    • Kalinec, G.M.1    Thein, P.2    Parsa, A.3    Yorgason, J.4    Luxford, W.5    Urrutia, R.6
  • 155
    • 66449137379 scopus 로고    scopus 로고
    • GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
    • Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, et al. (2009). GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice. J Clin Invest 119: 1201-1215.
    • (2009) J Clin Invest , vol.119 , pp. 1201-1215
    • Kammoun, H.L.1    Chabanon, H.2    Hainault, I.3    Luquet, S.4    Magnan, C.5    Koike, T.6
  • 156
    • 84864338917 scopus 로고    scopus 로고
    • 2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes
    • 2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes. Hepatology 56: 594-604.
    • (2012) Hepatology , vol.56 , pp. 594-604
    • Kao, E.1    Shinohara, M.2    Feng, M.3    Lau, M.Y.4    Ji, C.5
  • 157
    • 84904326275 scopus 로고    scopus 로고
    • Therapeutic dose of acetaminophen as a possible risk factor for acute kidney injury: learning from two healthy young adult cases
    • Kato H, Fujigaki Y, Inoue R, Asakawa S, Shin S, Shima T, et al. (2014). Therapeutic dose of acetaminophen as a possible risk factor for acute kidney injury: learning from two healthy young adult cases. Intern Med 53: 1531-1534.
    • (2014) Intern Med , vol.53 , pp. 1531-1534
    • Kato, H.1    Fujigaki, Y.2    Inoue, R.3    Asakawa, S.4    Shin, S.5    Shima, T.6
  • 158
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
    • Kaufman RJ (1999). Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13: 1211-1233.
    • (1999) Genes Dev , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 159
    • 38349057749 scopus 로고    scopus 로고
    • The protective effect of N-acetylcysteine against cyclosporine A-induced hepatotoxicity in rats
    • Kaya H, Koc A, Sogut S, Duru M, Yilmaz HR, Uz E, et al. (2008). The protective effect of N-acetylcysteine against cyclosporine A-induced hepatotoxicity in rats. J Appl Toxicol 28: 15-20.
    • (2008) J Appl Toxicol , vol.28 , pp. 15-20
    • Kaya, H.1    Koc, A.2    Sogut, S.3    Duru, M.4    Yilmaz, H.R.5    Uz, E.6
  • 161
    • 84881128520 scopus 로고    scopus 로고
    • Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity
    • Khan MA, Liu J, Kumar G, Skapek SX, Falck JR, Imig JD (2013). Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity. FASEB J 27: 2946-2956.
    • (2013) FASEB J , vol.27 , pp. 2946-2956
    • Khan, M.A.1    Liu, J.2    Kumar, G.3    Skapek, S.X.4    Falck, J.R.5    Imig, J.D.6
  • 162
    • 80052523444 scopus 로고    scopus 로고
    • Aggravation of bleomycin-induced pulmonary inflammation and fibrosis in mice lacking peroxiredoxin I
    • Kikuchi N, Ishii Y, Morishima Y, Yageta Y, Haraguchi N, Yamadori T, et al. (2011). Aggravation of bleomycin-induced pulmonary inflammation and fibrosis in mice lacking peroxiredoxin I. Am J Respir Cell Mol Biol 45: 600-609.
    • (2011) Am J Respir Cell Mol Biol , vol.45 , pp. 600-609
    • Kikuchi, N.1    Ishii, Y.2    Morishima, Y.3    Yageta, Y.4    Haraguchi, N.5    Yamadori, T.6
  • 163
    • 57049117856 scopus 로고    scopus 로고
    • Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
    • Kim I, Xu W, Reed JC (2008). Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 7: 1013-1030.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 1013-1030
    • Kim, I.1    Xu, W.2    Reed, J.C.3
  • 164
    • 84957695116 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells
    • King YA, Chiu YJ, Chen HP, Kuo DH, Lu CC, Yang JS (2015). Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells. Environ Toxicol. doi:10.1002/tox.22046.
    • (2015) Environ Toxicol
    • King, Y.A.1    Chiu, Y.J.2    Chen, H.P.3    Kuo, D.H.4    Lu, C.C.5    Yang, J.S.6
  • 165
    • 52449128023 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces
    • Kitamura M (2008). Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces. Am J Physiol Renal Physiol 295: F323-F334.
    • (2008) Am J Physiol Renal Physiol , vol.295 , pp. F323-F334
    • Kitamura, M.1
  • 166
    • 84876480452 scopus 로고    scopus 로고
    • Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT)
    • Knights KM, Rowland A, Miners JO (2013). Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT). Br J Clin Pharmacol 76: 587-602.
    • (2013) Br J Clin Pharmacol , vol.76 , pp. 587-602
    • Knights, K.M.1    Rowland, A.2    Miners, J.O.3
  • 167
    • 80255126097 scopus 로고    scopus 로고
    • Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity
    • Knockaert L, Fromenty B, Robin MA (2011). Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity. FEBS J 278: 4252-4260.
    • (2011) FEBS J , vol.278 , pp. 4252-4260
    • Knockaert, L.1    Fromenty, B.2    Robin, M.A.3
  • 169
    • 84877093333 scopus 로고    scopus 로고
    • Erythropoietin protects against cisplatin-induced nephrotoxicity by attenuating endoplasmic reticulum stress-induced apoptosis
    • Kong D, Zhuo L, Gao C, Shi S, Wang N, Huang Z, et al. (2013). Erythropoietin protects against cisplatin-induced nephrotoxicity by attenuating endoplasmic reticulum stress-induced apoptosis. J Nephrol 26: 219-227.
    • (2013) J Nephrol , vol.26 , pp. 219-227
    • Kong, D.1    Zhuo, L.2    Gao, C.3    Shi, S.4    Wang, N.5    Huang, Z.6
  • 170
    • 33745677648 scopus 로고    scopus 로고
    • Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons
    • Kosuge Y, Sakikubo T, Ishige K, Ito Y (2006). Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons. Neurochem Int 49: 285-293.
    • (2006) Neurochem Int , vol.49 , pp. 285-293
    • Kosuge, Y.1    Sakikubo, T.2    Ishige, K.3    Ito, Y.4
  • 171
    • 0028143028 scopus 로고
    • Mechanism of covalent adduct formation of diclofenac to rat hepatic microsomal proteins. Retention of the glucuronic acid moiety in the adduct
    • Kretz-Rommel A, Boelsterli UA (1994). Mechanism of covalent adduct formation of diclofenac to rat hepatic microsomal proteins. Retention of the glucuronic acid moiety in the adduct. Drug Metab Dispos 22: 956-961.
    • (1994) Drug Metab Dispos , vol.22 , pp. 956-961
    • Kretz-Rommel, A.1    Boelsterli, U.A.2
  • 172
    • 0030933609 scopus 로고    scopus 로고
    • Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain
    • Kruidering M, Van de Water B, de Heer E, Mulder GJ, Nagelkerke JF (1997) Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain. J Pharmacol Exp Ther 280: 638-649.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 638-649
    • Kruidering, M.1    Van de Water, B.2    de Heer, E.3    Mulder, G.J.4    Nagelkerke, J.F.5
  • 173
    • 0025326783 scopus 로고
    • Side-effect profile of cyclosporin A in patients treated for psoriasis
    • Krupp P, Monka C (1990). Side-effect profile of cyclosporin A in patients treated for psoriasis. Br J Dermatol 122: 47-56.
    • (1990) Br J Dermatol , vol.122 , pp. 47-56
    • Krupp, P.1    Monka, C.2
  • 174
    • 84902250809 scopus 로고    scopus 로고
    • Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells
    • Kumar S, Yedjou CG, Tchounwou PB (2014). Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells. J Exp Clin Cancer Res 33: 42.
    • (2014) J Exp Clin Cancer Res , vol.33 , pp. 42
    • Kumar, S.1    Yedjou, C.G.2    Tchounwou, P.B.3
  • 175
    • 0016241906 scopus 로고
    • Tunicamycin: an inhibitor of yeast glycoprotein synthesis
    • Kuo SC, Lampen JO (1974). Tunicamycin: an inhibitor of yeast glycoprotein synthesis. Biochem Biophys Res Commun 58: 287-295.
    • (1974) Biochem Biophys Res Commun , vol.58 , pp. 287-295
    • Kuo, S.C.1    Lampen, J.O.2
  • 176
    • 55949124005 scopus 로고    scopus 로고
    • Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies
    • Labbe G, Pessayre D, Fromenty B (2008). Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies. Fundam Clin Pharmacol 22: 335-353.
    • (2008) Fundam Clin Pharmacol , vol.22 , pp. 335-353
    • Labbe, G.1    Pessayre, D.2    Fromenty, B.3
  • 177
    • 84855970215 scopus 로고    scopus 로고
    • Does endoplasmic reticulum stress participate in APD-induced hepatic metabolic dysregulation?
    • Lauressergues E, Bert E, Duriez P, Hum D, Majd Z, Staels B, et al. (2012). Does endoplasmic reticulum stress participate in APD-induced hepatic metabolic dysregulation? Neuropharmacology 62: 784-796.
    • (2012) Neuropharmacology , vol.62 , pp. 784-796
    • Lauressergues, E.1    Bert, E.2    Duriez, P.3    Hum, D.4    Majd, Z.5    Staels, B.6
  • 179
    • 0043193876 scopus 로고    scopus 로고
    • Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
    • Lee AH, Iwakoshi NN, Anderson KC, Glimcher LH (2003). Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc Natl Acad Sci USA 100: 9946-9951.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9946-9951
    • Lee, A.H.1    Iwakoshi, N.N.2    Anderson, K.C.3    Glimcher, L.H.4
  • 180
    • 84858987289 scopus 로고    scopus 로고
    • Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model
    • Lee JS, Zheng Z, Mendez R, Ha SW, Xie Y, Zhang K (2012). Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model. Toxicol Lett 211: 29-38.
    • (2012) Toxicol Lett , vol.211 , pp. 29-38
    • Lee, J.S.1    Zheng, Z.2    Mendez, R.3    Ha, S.W.4    Xie, Y.5    Zhang, K.6
  • 183
    • 84855873678 scopus 로고    scopus 로고
    • Metabolic activation in drug-induced liver injury
    • Leung L, Kalgutkar AS, Obach RS (2012). Metabolic activation in drug-induced liver injury. Drug Metab Rev 44: 18-33.
    • (2012) Drug Metab Rev , vol.44 , pp. 18-33
    • Leung, L.1    Kalgutkar, A.S.2    Obach, R.S.3
  • 184
    • 84863959263 scopus 로고    scopus 로고
    • ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death
    • Lhotak S, Sood S, Brimble E, Carlisle RE, Colgan SM, Mazzetti A, et al. (2012). ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death. Am J Physiol Renal Physiol 303: F266-F278.
    • (2012) Am J Physiol Renal Physiol , vol.303 , pp. F266-F278
    • Lhotak, S.1    Sood, S.2    Brimble, E.3    Carlisle, R.E.4    Colgan, S.M.5    Mazzetti, A.6
  • 185
    • 0023711157 scopus 로고
    • Covalent binding of platinum to renal protein from sensitive and resistant guinea pigs treated with cisplatin: possible role in nephrotoxicity
    • Litterst CL, Schweitzer VG (1988). Covalent binding of platinum to renal protein from sensitive and resistant guinea pigs treated with cisplatin: possible role in nephrotoxicity. Res Commun Chem Pathol Pharmacol 61: 35-48.
    • (1988) Res Commun Chem Pathol Pharmacol , vol.61 , pp. 35-48
    • Litterst, C.L.1    Schweitzer, V.G.2
  • 186
    • 27744500069 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis
    • Liu H, Baliga R (2005). Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis. J Am Soc Nephrol 16: 1985-1992.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1985-1992
    • Liu, H.1    Baliga, R.2
  • 187
    • 84926155847 scopus 로고    scopus 로고
    • Ginsenoside Rg1 protects chronic cyclosporin a nephropathy from tubular cell apoptosis by inhibiting endoplasmic reticulum stress in rats
    • Liu QF, Deng ZY, Ye JM, He AL, Li SS (2015). Ginsenoside Rg1 protects chronic cyclosporin a nephropathy from tubular cell apoptosis by inhibiting endoplasmic reticulum stress in rats. Transplant Proc 47: 566-569.
    • (2015) Transplant Proc , vol.47 , pp. 566-569
    • Liu, Q.F.1    Deng, Z.Y.2    Ye, J.M.3    He, A.L.4    Li, S.S.5
  • 188
    • 84920570441 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress as a novel mechanism in amiodarone-induced destructive thyroiditis
    • Lombardi A, Inabnet WB, Owen R, Farenholtz KE, Tomer Y (2015). Endoplasmic reticulum stress as a novel mechanism in amiodarone-induced destructive thyroiditis. J Clin Endocrinol Metab 100: E1-E10.
    • (2015) J Clin Endocrinol Metab , vol.100 , pp. E1-E10
    • Lombardi, A.1    Inabnet, W.B.2    Owen, R.3    Farenholtz, K.E.4    Tomer, Y.5
  • 190
    • 34547644483 scopus 로고    scopus 로고
    • Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
    • Lu J, Chew EH, Holmgren A (2007). Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. Proc Natl Acad Sci USA 104: 12288-12293.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12288-12293
    • Lu, J.1    Chew, E.H.2    Holmgren, A.3
  • 191
    • 79651473588 scopus 로고    scopus 로고
    • Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways
    • Lu TH, Su CC, Chen YW, Yang CY, Wu CC, Hung DZ, et al. (2011). Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways. Toxicol Lett 201: 15-26.
    • (2011) Toxicol Lett , vol.201 , pp. 15-26
    • Lu, T.H.1    Su, C.C.2    Chen, Y.W.3    Yang, C.Y.4    Wu, C.C.5    Hung, D.Z.6
  • 192
    • 0030886976 scopus 로고    scopus 로고
    • Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases
    • Luo Y, Bond JD, Ingram VM (1997). Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases. Proc Natl Acad Sci USA 94: 9705-9710.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9705-9710
    • Luo, Y.1    Bond, J.D.2    Ingram, V.M.3
  • 194
    • 84881620320 scopus 로고    scopus 로고
    • Cisplatin: an old drug with a newfound efficacy - from mechanisms of action to cytotoxicity
    • Maccio A, Madeddu C (2013). Cisplatin: an old drug with a newfound efficacy - from mechanisms of action to cytotoxicity. Expert Opin Pharmacother 14: 1839-1857.
    • (2013) Expert Opin Pharmacother , vol.14 , pp. 1839-1857
    • Maccio, A.1    Madeddu, C.2
  • 195
    • 79952803065 scopus 로고    scopus 로고
    • Cardiovascular risk factors in patients on long-term treatment with nevirapine- or efavirenz-based regimens
    • Maggi P, Bellacosa C, Carito V, Perilli F, Lillo A, Volpe A, et al. (2011). Cardiovascular risk factors in patients on long-term treatment with nevirapine- or efavirenz-based regimens. J Antimicrob Chemother 66: 896-900.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 896-900
    • Maggi, P.1    Bellacosa, C.2    Carito, V.3    Perilli, F.4    Lillo, A.5    Volpe, A.6
  • 196
    • 73949095511 scopus 로고    scopus 로고
    • Efavirenz: a decade of clinical experience in the treatment of HIV
    • Maggiolo F (2009). Efavirenz: a decade of clinical experience in the treatment of HIV. J Antimicrob Chemother 64: 910-928.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 910-928
    • Maggiolo, F.1
  • 197
    • 84936147811 scopus 로고    scopus 로고
    • Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis
    • Mahavadi P, Henneke I, Ruppert C, Knudsen L, Venkatesan S, Liebisch G, et al. (2014). Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis. Toxicol Sci 142: 285-297.
    • (2014) Toxicol Sci , vol.142 , pp. 285-297
    • Mahavadi, P.1    Henneke, I.2    Ruppert, C.3    Knudsen, L.4    Venkatesan, S.5    Liebisch, G.6
  • 198
    • 79952708723 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in liver disease
    • Malhi H, Kaufman RJ (2011). Endoplasmic reticulum stress in liver disease. J Hepatol 54: 795-809.
    • (2011) J Hepatol , vol.54 , pp. 795-809
    • Malhi, H.1    Kaufman, R.J.2
  • 199
    • 35848957485 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?
    • Malhotra JD, Kaufman RJ (2007). Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid Redox Signal 9: 2277-2293.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 2277-2293
    • Malhotra, J.D.1    Kaufman, R.J.2
  • 201
    • 0037646503 scopus 로고    scopus 로고
    • Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling
    • Mandic A, Hansson J, Linder S, Shoshan MC (2003). Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling. J Biol Chem 278: 9100-9106.
    • (2003) J Biol Chem , vol.278 , pp. 9100-9106
    • Mandic, A.1    Hansson, J.2    Linder, S.3    Shoshan, M.C.4
  • 202
    • 10644233167 scopus 로고    scopus 로고
    • CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
    • Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, et al. (2004). CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 18: 3066-3077.
    • (2004) Genes Dev , vol.18 , pp. 3066-3077
    • Marciniak, S.J.1    Yun, C.Y.2    Oyadomari, S.3    Novoa, I.4    Zhang, Y.5    Jungreis, R.6
  • 204
    • 77949410471 scopus 로고    scopus 로고
    • Impact of biomarker development on drug safety assessment
    • Marrer E, Dieterle F (2010). Impact of biomarker development on drug safety assessment. Toxicol Appl Pharmacol 243: 167-179.
    • (2010) Toxicol Appl Pharmacol , vol.243 , pp. 167-179
    • Marrer, E.1    Dieterle, F.2
  • 207
    • 84937555459 scopus 로고    scopus 로고
    • The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury
    • McGill MR, Du K, Xie Y, Bajt ML, Ding WX, Jaeschke H (2015). The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury. Xenobiotica 45: 442-449.
    • (2015) Xenobiotica , vol.45 , pp. 442-449
    • McGill, M.R.1    Du, K.2    Xie, Y.3    Bajt, M.L.4    Ding, W.X.5    Jaeschke, H.6
  • 208
    • 0242408869 scopus 로고    scopus 로고
    • Relationship between levels of insulin or triglycerides and serum concentrations of the atypical antipsychotics clozapine and olanzapine in patients on treatment with therapeutic doses
    • Melkersson KI, Dahl ML (2003). Relationship between levels of insulin or triglycerides and serum concentrations of the atypical antipsychotics clozapine and olanzapine in patients on treatment with therapeutic doses. Psychopharmacology 170: 157-166.
    • (2003) Psychopharmacology , vol.170 , pp. 157-166
    • Melkersson, K.I.1    Dahl, M.L.2
  • 209
    • 84861653489 scopus 로고    scopus 로고
    • Ritonavir-induced lipoatrophy and dyslipidaemia is reversed by the anti-inflammatory drug leflunomide in a PPAR-γ-dependent manner
    • Mencarelli A, Francisci D, Renga B, D'Amore C, Cipriani S, Basile F, et al. (2012). Ritonavir-induced lipoatrophy and dyslipidaemia is reversed by the anti-inflammatory drug leflunomide in a PPAR-γ-dependent manner. Antivir Ther 17: 669-678.
    • (2012) Antivir Ther , vol.17 , pp. 669-678
    • Mencarelli, A.1    Francisci, D.2    Renga, B.3    D'Amore, C.4    Cipriani, S.5    Basile, F.6
  • 210
    • 84904462459 scopus 로고    scopus 로고
    • Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease
    • Michaut A, Moreau C, Robin MA, Fromenty B (2014). Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease. Liver Int 34: e171-e179.
    • (2014) Liver Int , vol.34 , pp. e171-e179
    • Michaut, A.1    Moreau, C.2    Robin, M.A.3    Fromenty, B.4
  • 211
    • 84902000342 scopus 로고    scopus 로고
    • Chemotherapy-induced neuropathy: A comprehensive survey
    • Miltenburg NC, Boogerd W (2014). Chemotherapy-induced neuropathy: A comprehensive survey. Cancer Treat Rev 40: 872-882.
    • (2014) Cancer Treat Rev , vol.40 , pp. 872-882
    • Miltenburg, N.C.1    Boogerd, W.2
  • 212
    • 84855448154 scopus 로고    scopus 로고
    • Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy
    • Mukhopadhyay P, Horvath B, Zsengeller Z, Zielonka J, Tanchian G, Holovac E, et al. (2012). Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy. Free Radic Biol Med 52: 497-506.
    • (2012) Free Radic Biol Med , vol.52 , pp. 497-506
    • Mukhopadhyay, P.1    Horvath, B.2    Zsengeller, Z.3    Zielonka, J.4    Tanchian, G.5    Holovac, E.6
  • 213
    • 84883807669 scopus 로고    scopus 로고
    • Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes
    • Nadanaciva S, Aleo MD, Strock CJ, Stedman DB, Wang H, Will Y (2013). Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Toxicol Appl Pharmacol 272: 272-280.
    • (2013) Toxicol Appl Pharmacol , vol.272 , pp. 272-280
    • Nadanaciva, S.1    Aleo, M.D.2    Strock, C.J.3    Stedman, D.B.4    Wang, H.5    Will, Y.6
  • 214
    • 0023619257 scopus 로고
    • The covalent binding of cyclosporin A to rat liver macromolecules in vivo and in vitro: the role of cytochrome P-450
    • Nagelkerke JF, Tijdens RB, Schwarz EP, Winters MF, Paul LC, Mulder GJ (1987). The covalent binding of cyclosporin A to rat liver macromolecules in vivo and in vitro: the role of cytochrome P-450. Toxicology 47: 277-284.
    • (1987) Toxicology , vol.47 , pp. 277-284
    • Nagelkerke, J.F.1    Tijdens, R.B.2    Schwarz, E.P.3    Winters, M.F.4    Paul, L.C.5    Mulder, G.J.6
  • 216
    • 75449085494 scopus 로고    scopus 로고
    • BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury
    • Nagy G, Szarka A, Lotz G, Doczi J, Wunderlich L, Kiss A, et al. (2010). BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury. Toxicol Appl Pharmacol 243: 96-103.
    • (2010) Toxicol Appl Pharmacol , vol.243 , pp. 96-103
    • Nagy, G.1    Szarka, A.2    Lotz, G.3    Doczi, J.4    Wunderlich, L.5    Kiss, A.6
  • 217
    • 0034698878 scopus 로고    scopus 로고
    • Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
    • Nakagawa T, Yuan J (2000). Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150: 887-894.
    • (2000) J Cell Biol , vol.150 , pp. 887-894
    • Nakagawa, T.1    Yuan, J.2
  • 218
    • 84928984957 scopus 로고    scopus 로고
    • Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes via the ER stress pathway
    • Narabayashi K, Ito Y, Eid N, Maemura K, Inoue T, Takeuchi T, et al. (2015). Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes via the ER stress pathway. J Gastroenterol 50: 541-554.
    • (2015) J Gastroenterol , vol.50 , pp. 541-554
    • Narabayashi, K.1    Ito, Y.2    Eid, N.3    Maemura, K.4    Inoue, T.5    Takeuchi, T.6
  • 220
    • 39849091344 scopus 로고    scopus 로고
    • Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells
    • Nicolescu AC, Ji Y, Comeau JL, Hill BC, Takahashi T, Brien JF, et al. (2008). Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells. Toxicol Appl Pharmacol 227: 370-379.
    • (2008) Toxicol Appl Pharmacol , vol.227 , pp. 370-379
    • Nicolescu, A.C.1    Ji, Y.2    Comeau, J.L.3    Hill, B.C.4    Takahashi, T.5    Brien, J.F.6
  • 221
    • 0038025823 scopus 로고    scopus 로고
    • Role of hydrogen peroxide in cyclosporine-induced renal tubular cell (LLC-PK1) injury
    • Nishida M, Ogawa H, Tamai M, Ishiwari K, Hamaoka K (2003). Role of hydrogen peroxide in cyclosporine-induced renal tubular cell (LLC-PK1) injury. J Pharmacol Sci 91: 255-258.
    • (2003) J Pharmacol Sci , vol.91 , pp. 255-258
    • Nishida, M.1    Ogawa, H.2    Tamai, M.3    Ishiwari, K.4    Hamaoka, K.5
  • 222
    • 84904758791 scopus 로고    scopus 로고
    • Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats
    • Niu X, de Graaf IA, van der Bij HA, Groothuis GM (2014). Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats. Toxicol In Vitro 28: 1296-1305.
    • (2014) Toxicol In Vitro , vol.28 , pp. 1296-1305
    • Niu, X.1    de Graaf, I.A.2    van der Bij, H.A.3    Groothuis, G.M.4
  • 224
    • 53549100467 scopus 로고    scopus 로고
    • Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose
    • Obach RS, Kalgutkar AS, Soglia JR, Zhao SX (2008). Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose. Chem Res Toxicol 21: 1814-1822.
    • (2008) Chem Res Toxicol , vol.21 , pp. 1814-1822
    • Obach, R.S.1    Kalgutkar, A.S.2    Soglia, J.R.3    Zhao, S.X.4
  • 225
    • 84859106438 scopus 로고    scopus 로고
    • Toxicoproteomic analysis of a mouse model of nonsteroidal anti-inflammatory drug-induced gastric ulcers
    • Ohyama K, Shiokawa A, Ito K, Masuyama R, Ichibangase T, Kishikawa N, et al. (2012). Toxicoproteomic analysis of a mouse model of nonsteroidal anti-inflammatory drug-induced gastric ulcers. Biochem Biophys Res Commun 420: 210-215.
    • (2012) Biochem Biophys Res Commun , vol.420 , pp. 210-215
    • Ohyama, K.1    Shiokawa, A.2    Ito, K.3    Masuyama, R.4    Ichibangase, T.5    Kishikawa, N.6
  • 226
    • 84881225025 scopus 로고    scopus 로고
    • The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation
    • Ozasa R, Okada T, Nadanaka S, Nagamine T, Zyryanova A, Harding H, et al. (2013). The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation. Cell Struct Funct 38: 183-195.
    • (2013) Cell Struct Funct , vol.38 , pp. 183-195
    • Ozasa, R.1    Okada, T.2    Nadanaka, S.3    Nagamine, T.4    Zyryanova, A.5    Harding, H.6
  • 227
    • 42149187768 scopus 로고    scopus 로고
    • Cisplatin nephrotoxicity: mechanisms and renoprotective strategies
    • Pabla N, Dong Z (2008). Cisplatin nephrotoxicity: mechanisms and renoprotective strategies. Kidney Int 73: 994-1007.
    • (2008) Kidney Int , vol.73 , pp. 994-1007
    • Pabla, N.1    Dong, Z.2
  • 229
    • 0037105651 scopus 로고    scopus 로고
    • The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells
    • Pajonk F, Himmelsbach J, Riess K, Sommer A, McBride WH (2002). The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells. Cancer Res 62: 5230-5235.
    • (2002) Cancer Res , vol.62 , pp. 5230-5235
    • Pajonk, F.1    Himmelsbach, J.2    Riess, K.3    Sommer, A.4    McBride, W.H.5
  • 230
    • 53749105061 scopus 로고    scopus 로고
    • Cyclosporine-induced endoplasmic reticulum stress triggers tubular phenotypic changes and death
    • Pallet N, Bouvier N, Bendjallabah A, Rabant M, Flinois JP, Hertig A, et al. (2008). Cyclosporine-induced endoplasmic reticulum stress triggers tubular phenotypic changes and death. Am J Transplant 8: 2283-2296.
    • (2008) Am J Transplant , vol.8 , pp. 2283-2296
    • Pallet, N.1    Bouvier, N.2    Bendjallabah, A.3    Rabant, M.4    Flinois, J.P.5    Hertig, A.6
  • 231
    • 0035871677 scopus 로고    scopus 로고
    • Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes
    • Palomero J, Galan AI, Munoz ME, Tunon MJ, Gonzalez-Gallego J, Jimenez R (2001). Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes. Free Radic Biol Med 30: 836-845.
    • (2001) Free Radic Biol Med , vol.30 , pp. 836-845
    • Palomero, J.1    Galan, A.I.2    Munoz, M.E.3    Tunon, M.J.4    Gonzalez-Gallego, J.5    Jimenez, R.6
  • 232
    • 41649087623 scopus 로고    scopus 로고
    • An overview of drug-induced acute kidney injury
    • Pannu N, Nadim MK (2008). An overview of drug-induced acute kidney injury. Crit Care Med 36: S216-S223.
    • (2008) Crit Care Med , vol.36 , pp. S216-S223
    • Pannu, N.1    Nadim, M.K.2
  • 234
    • 21744443279 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors
    • Parker RA, Flint OP, Mulvey R, Elosua C, Wang F, Fenderson W, et al. (2005). Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors. Mol Pharmacol 67: 1909-1919.
    • (2005) Mol Pharmacol , vol.67 , pp. 1909-1919
    • Parker, R.A.1    Flint, O.P.2    Mulvey, R.3    Elosua, C.4    Wang, F.5    Fenderson, W.6
  • 235
    • 0026712224 scopus 로고
    • Properties of the reaction of cis-dichlorodiammineplatinum(II) with metallothionein
    • Pattanaik A, Bachowski G, Laib J, Lemkuil D, Shaw CF, Petering DH, et al. (1992). Properties of the reaction of cis-dichlorodiammineplatinum(II) with metallothionein. J Biol Chem 267: 16121-16128.
    • (1992) J Biol Chem , vol.267 , pp. 16121-16128
    • Pattanaik, A.1    Bachowski, G.2    Laib, J.3    Lemkuil, D.4    Shaw, C.F.5    Petering, D.H.6
  • 236
    • 37349002016 scopus 로고    scopus 로고
    • Dithiothreitol abrogates the effect of arsenic trioxide on normal rat liver mitochondria and human hepatocellular carcinoma cells
    • Paul MK, Kumar R, Mukhopadhyay AK (2008). Dithiothreitol abrogates the effect of arsenic trioxide on normal rat liver mitochondria and human hepatocellular carcinoma cells. Toxicol Appl Pharmacol 226: 140-152.
    • (2008) Toxicol Appl Pharmacol , vol.226 , pp. 140-152
    • Paul, M.K.1    Kumar, R.2    Mukhopadhyay, A.K.3
  • 237
    • 84890376710 scopus 로고    scopus 로고
    • Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11)
    • Pedersen JM, Matsson P, Bergström CA, Hoogstraate J, Noren A, LeCluyse EL, et al. (2013). Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). Toxicol Sci 136: 328-343.
    • (2013) Toxicol Sci , vol.136 , pp. 328-343
    • Pedersen, J.M.1    Matsson, P.2    Bergström, C.A.3    Hoogstraate, J.4    Noren, A.5    LeCluyse, E.L.6
  • 238
    • 0141509869 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism
    • Pelicano H, Feng L, Zhou Y, Carew JS, Hileman EO, Plunkett W, et al. (2003). Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J Biol Chem 278: 37832-37839.
    • (2003) J Biol Chem , vol.278 , pp. 37832-37839
    • Pelicano, H.1    Feng, L.2    Zhou, Y.3    Carew, J.S.4    Hileman, E.O.5    Plunkett, W.6
  • 239
    • 34547918307 scopus 로고    scopus 로고
    • Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys
    • Peyrou M, Hanna PE, Cribb AE (2007). Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys. Toxicol Sci 99: 346-353.
    • (2007) Toxicol Sci , vol.99 , pp. 346-353
    • Peyrou, M.1    Hanna, P.E.2    Cribb, A.E.3
  • 242
    • 84866596506 scopus 로고    scopus 로고
    • Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria
    • Porceddu M, Buron N, Roussel C, Labbe G, Fromenty B, Borgne-Sanchez A (2012). Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria. Toxicol Sci 129: 332-345.
    • (2012) Toxicol Sci , vol.129 , pp. 332-345
    • Porceddu, M.1    Buron, N.2    Roussel, C.3    Labbe, G.4    Fromenty, B.5    Borgne-Sanchez, A.6
  • 243
    • 0025295133 scopus 로고
    • Immunochemical quantitation of 3-(cystein-S-yl)acetaminophen protein adducts in subcellular liver fractions following a hepatotoxic dose of acetaminophen
    • Pumford NR, Roberts DW, Benson RW, Hinson JA (1990). Immunochemical quantitation of 3-(cystein-S-yl)acetaminophen protein adducts in subcellular liver fractions following a hepatotoxic dose of acetaminophen. Biochem Pharmacol 40: 573-579.
    • (1990) Biochem Pharmacol , vol.40 , pp. 573-579
    • Pumford, N.R.1    Roberts, D.W.2    Benson, R.W.3    Hinson, J.A.4
  • 244
    • 84907195339 scopus 로고    scopus 로고
    • Efavirenz induces neuronal autophagy and mitochondrial alterations
    • Purnell PR, Fox HS (2014). Efavirenz induces neuronal autophagy and mitochondrial alterations. J Pharmacol Exp Ther 351: 250-258.
    • (2014) J Pharmacol Exp Ther , vol.351 , pp. 250-258
    • Purnell, P.R.1    Fox, H.S.2
  • 245
    • 36348961452 scopus 로고    scopus 로고
    • HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress
    • Pyrko P, Kardosh A, Wang W, Xiong W, Schönthal AH, Chen TC (2007). HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress. Cancer Res 67: 10920-10928.
    • (2007) Cancer Res , vol.67 , pp. 10920-10928
    • Pyrko, P.1    Kardosh, A.2    Wang, W.3    Xiong, W.4    Schönthal, A.H.5    Chen, T.C.6
  • 246
    • 84904913834 scopus 로고    scopus 로고
    • Nrf2 protects against furosemide-induced hepatotoxicity
    • Qu Q, Liu J, Zhou HH, Klaassen CD (2014). Nrf2 protects against furosemide-induced hepatotoxicity. Toxicology 324: 35-42.
    • (2014) Toxicology , vol.324 , pp. 35-42
    • Qu, Q.1    Liu, J.2    Zhou, H.H.3    Klaassen, C.D.4
  • 247
    • 0019975343 scopus 로고
    • Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effects on prostaglandin production
    • Rainsford KD, Willis C (1982). Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effects on prostaglandin production. Dig Dis Sci 27: 624-635.
    • (1982) Dig Dis Sci , vol.27 , pp. 624-635
    • Rainsford, K.D.1    Willis, C.2
  • 249
    • 0035823579 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
    • Rao RV, Hermel E, Castro-Obregon S, del Rio G, Ellerby LM, Ellerby HM, et al. (2001). Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J Biol Chem 276: 33869-33874.
    • (2001) J Biol Chem , vol.276 , pp. 33869-33874
    • Rao, R.V.1    Hermel, E.2    Castro-Obregon, S.3    del Rio, G.4    Ellerby, L.M.5    Ellerby, H.M.6
  • 250
    • 84876379067 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism in brain: functional roles and their implications
    • Ravindranath V, Strobel HW (2013). Cytochrome P450-mediated metabolism in brain: functional roles and their implications. Expert Opin Drug Metab Toxicol 9: 551-558.
    • (2013) Expert Opin Drug Metab Toxicol , vol.9 , pp. 551-558
    • Ravindranath, V.1    Strobel, H.W.2
  • 251
    • 78650438578 scopus 로고    scopus 로고
    • Reviewing the safety of erlotinib in non-small cell lung cancer
    • Reck M, Mok T, Wolf J, Heigener D, Wu YL (2011). Reviewing the safety of erlotinib in non-small cell lung cancer. Expert Opin Drug Saf 10: 147-157.
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 147-157
    • Reck, M.1    Mok, T.2    Wolf, J.3    Heigener, D.4    Wu, Y.L.5
  • 253
    • 84953887472 scopus 로고    scopus 로고
    • Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages
    • Rekha RS, Rao Muvva SJ, Wan M, Raqib R, Bergman P, Brighenti S, et al. (2015). Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages. Autophagy 11: 1688-1699.
    • (2015) Autophagy , vol.11 , pp. 1688-1699
    • Rekha, R.S.1    Rao Muvva, S.J.2    Wan, M.3    Raqib, R.4    Bergman, P.5    Brighenti, S.6
  • 254
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatment - pharmacological mechanisms
    • Reynolds GP, Kirk SL (2010). Metabolic side effects of antipsychotic drug treatment - pharmacological mechanisms. Pharmacol Ther 125: 169-179.
    • (2010) Pharmacol Ther , vol.125 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 256
    • 3042701257 scopus 로고    scopus 로고
    • Time dependent risk of gastrointestinal complications induced by non-steroidal anti-inflammatory drug use: a consensus statement using a meta-analytic approach
    • Richy F, Bruyere O, Ethgen O, Rabenda V, Bouvenot G, Audran M, et al. (2004). Time dependent risk of gastrointestinal complications induced by non-steroidal anti-inflammatory drug use: a consensus statement using a meta-analytic approach. Ann Rheum Dis 63: 759-766.
    • (2004) Ann Rheum Dis , vol.63 , pp. 759-766
    • Richy, F.1    Bruyere, O.2    Ethgen, O.3    Rabenda, V.4    Bouvenot, G.5    Audran, M.6
  • 257
    • 84945481150 scopus 로고    scopus 로고
    • Metabolic syndrome and obesity among users of second generation antipsychotics: A global challenge for modern psychopharmacology
    • Rojo LE, Gaspar PA, Silva H, Risco L, Arena P, Cubillos-Robles K, et al. (2015). Metabolic syndrome and obesity among users of second generation antipsychotics: A global challenge for modern psychopharmacology. Pharmacol Res. doi:10.1016/j.phrs.2015.07.022.
    • (2015) Pharmacol Res
    • Rojo, L.E.1    Gaspar, P.A.2    Silva, H.3    Risco, L.4    Arena, P.5    Cubillos-Robles, K.6
  • 259
    • 84862487151 scopus 로고    scopus 로고
    • Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease
    • Roy A, Ghosh A, Jana A, Liu X, Brahmachari S, Gendelman HE, et al. (2012). Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. PLoS ONE 7: e38113.
    • (2012) PLoS ONE , vol.7
    • Roy, A.1    Ghosh, A.2    Jana, A.3    Liu, X.4    Brahmachari, S.5    Gendelman, H.E.6
  • 260
    • 0036147966 scopus 로고    scopus 로고
    • Genomics and proteomics analysis of acetaminophen toxicity in mouse liver
    • Ruepp SU, Tonge RP, Shaw J, Wallis N, Pognan F (2002). Genomics and proteomics analysis of acetaminophen toxicity in mouse liver. Toxicol Sci 65: 135-150.
    • (2002) Toxicol Sci , vol.65 , pp. 135-150
    • Ruepp, S.U.1    Tonge, R.P.2    Shaw, J.3    Wallis, N.4    Pognan, F.5
  • 261
    • 57049111040 scopus 로고    scopus 로고
    • UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators
    • Rutkowski DT, Wu J, Back SH, Callaghan MU, Ferris SP, Iqbal J, et al. (2008). UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Dev Cell 15: 829-840.
    • (2008) Dev Cell , vol.15 , pp. 829-840
    • Rutkowski, D.T.1    Wu, J.2    Back, S.H.3    Callaghan, M.U.4    Ferris, S.P.5    Iqbal, J.6
  • 262
    • 0027936204 scopus 로고
    • Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins
    • Sadrieh N, Thomas PE (1994). Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins. Toxicol Appl Pharmacol 127: 222-232.
    • (1994) Toxicol Appl Pharmacol , vol.127 , pp. 222-232
    • Sadrieh, N.1    Thomas, P.E.2
  • 263
    • 77955979773 scopus 로고    scopus 로고
    • Methods for monitoring endoplasmic reticulum stress and the unfolded protein response
    • Samali A, Fitzgerald U, Deegan S, Gupta S (2010). Methods for monitoring endoplasmic reticulum stress and the unfolded protein response. Int J Cell Biol 2010: 830307.
    • (2010) Int J Cell Biol , vol.2010 , pp. 830307
    • Samali, A.1    Fitzgerald, U.2    Deegan, S.3    Gupta, S.4
  • 264
    • 84887620237 scopus 로고    scopus 로고
    • ER stress-induced cell death mechanisms
    • Sano R, Reed JC (2013). ER stress-induced cell death mechanisms. Biochim Biophys Acta 1833: 3460-3470.
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 3460-3470
    • Sano, R.1    Reed, J.C.2
  • 266
    • 41349119625 scopus 로고    scopus 로고
    • Drug-induced mitochondrial dysfunction in cardiac and skeletal muscle injury
    • Sardao VA, Pereira SL, Oliveira PJ (2008). Drug-induced mitochondrial dysfunction in cardiac and skeletal muscle injury. Expert Opin Drug Saf 7: 129-146.
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 129-146
    • Sardao, V.A.1    Pereira, S.L.2    Oliveira, P.J.3
  • 267
    • 84855821174 scopus 로고    scopus 로고
    • A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells
    • Sarro E, Jacobs-Cacha C, Itarte E, Meseguer A (2012). A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells. Toxicol Appl Pharmacol 258: 275-287.
    • (2012) Toxicol Appl Pharmacol , vol.258 , pp. 275-287
    • Sarro, E.1    Jacobs-Cacha, C.2    Itarte, E.3    Meseguer, A.4
  • 268
    • 33745002275 scopus 로고    scopus 로고
    • Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromes
    • Schiller GJ, Slack J, Hainsworth JD, Mason J, Saleh M, Rizzieri D, et al. (2006). Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromes. J Clin Oncol 24: 2456-2464.
    • (2006) J Clin Oncol , vol.24 , pp. 2456-2464
    • Schiller, G.J.1    Slack, J.2    Hainsworth, J.D.3    Mason, J.4    Saleh, M.5    Rizzieri, D.6
  • 270
    • 85044357068 scopus 로고    scopus 로고
    • Alterations of mitochondrial DNA in liver diseases
    • in N. Kaplowitz and D. Han, eds. Taylor & Francis, New-York.
    • Schon E, Fromenty B (2016). Alterations of mitochondrial DNA in liver diseases. Pp. 283-313 in N. Kaplowitz and D. Han, eds. Mitochondria in Liver Disease. Taylor & Francis, New-York.
    • (2016) Mitochondria in Liver Disease , pp. 283-313
    • Schon, E.1    Fromenty, B.2
  • 271
    • 84900295626 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: its role in disease and novel prospects for therapy
    • Schönthal AH (2012). Endoplasmic reticulum stress: its role in disease and novel prospects for therapy. Scientifica 2012: 857516.
    • (2012) Scientifica , vol.2012 , pp. 857516
    • Schönthal, A.H.1
  • 274
    • 0027275820 scopus 로고
    • Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition
    • Serino F, Grevel J, Napoli KL, Kahan BD, Strobel HW (1993). Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition. Mol Cell Biochem 122: 101-112.
    • (1993) Mol Cell Biochem , vol.122 , pp. 101-112
    • Serino, F.1    Grevel, J.2    Napoli, K.L.3    Kahan, B.D.4    Strobel, H.W.5
  • 276
    • 38049139423 scopus 로고    scopus 로고
    • Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation
    • Servais H, Ortiz A, Devuyst O, Denamur S, Tulkens PM, Mingeot-Leclercq MP (2008). Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation. Apoptosis 13: 11-32.
    • (2008) Apoptosis , vol.13 , pp. 11-32
    • Servais, H.1    Ortiz, A.2    Devuyst, O.3    Denamur, S.4    Tulkens, P.M.5    Mingeot-Leclercq, M.P.6
  • 277
    • 41449116766 scopus 로고    scopus 로고
    • Ero1 and redox homeostasis in the endoplasmic reticulum
    • Sevier CS, Kaiser CA (2008). Ero1 and redox homeostasis in the endoplasmic reticulum. Biochim Biophys Acta 1783: 549-556.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 549-556
    • Sevier, C.S.1    Kaiser, C.A.2
  • 278
    • 84913606473 scopus 로고    scopus 로고
    • Different dose-dependent mechanisms are involved in early cyclosporine A-induced cholestatic effects in HepaRG cells
    • Sharanek A, Azzi PB, Al-Attrache H, Savary CC, Humbert L, Rainteau D, et al. (2014). Different dose-dependent mechanisms are involved in early cyclosporine A-induced cholestatic effects in HepaRG cells. Toxicol Sci 141: 244-253.
    • (2014) Toxicol Sci , vol.141 , pp. 244-253
    • Sharanek, A.1    Azzi, P.B.2    Al-Attrache, H.3    Savary, C.C.4    Humbert, L.5    Rainteau, D.6
  • 279
    • 0030923869 scopus 로고    scopus 로고
    • Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease
    • Sheehan JP, Swerdlow RH, Miller SW, Davis RE, Parks JK, Parker WD, et al. (1997). Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease. J Neurosci 17: 4612-4622.
    • (1997) J Neurosci , vol.17 , pp. 4612-4622
    • Sheehan, J.P.1    Swerdlow, R.H.2    Miller, S.W.3    Davis, R.E.4    Parks, J.K.5    Parker, W.D.6
  • 280
    • 0030610687 scopus 로고    scopus 로고
    • Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients
    • Shen ZX, Chen GQ, Ni JH, Li XS, Xiong SM, Qiu QY, et al. (1997). Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 89: 3354-3360.
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Z.X.1    Chen, G.Q.2    Ni, J.H.3    Li, X.S.4    Xiong, S.M.5    Qiu, Q.Y.6
  • 281
    • 34447127578 scopus 로고    scopus 로고
    • Protein targets of reactive electrophiles in human liver microsomes
    • Shin NY, Liu Q, Stamer SL, Liebler DC (2007). Protein targets of reactive electrophiles in human liver microsomes. Chem Res Toxicol 20: 859-867.
    • (2007) Chem Res Toxicol , vol.20 , pp. 859-867
    • Shin, N.Y.1    Liu, Q.2    Stamer, S.L.3    Liebler, D.C.4
  • 282
    • 78649421033 scopus 로고    scopus 로고
    • Pathological adaptive responses of Schwann cells to endoplasmic reticulum stress in bortezomib-induced peripheral neuropathy
    • Shin YK, Jang SY, Lee HK, Jung J, Suh DJ, Seo SY, et al. (2010). Pathological adaptive responses of Schwann cells to endoplasmic reticulum stress in bortezomib-induced peripheral neuropathy. Glia 58: 1961-1976.
    • (2010) Glia , vol.58 , pp. 1961-1976
    • Shin, Y.K.1    Jang, S.Y.2    Lee, H.K.3    Jung, J.4    Suh, D.J.5    Seo, S.Y.6
  • 283
    • 0026502933 scopus 로고
    • Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporine nephrotoxicity
    • Smith SR, Creech EA, Schaffer AV, Martin LL, Rakhit A, Douglas FL, et al. (1992). Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporine nephrotoxicity. Kidney Int 41: 199-205.
    • (1992) Kidney Int , vol.41 , pp. 199-205
    • Smith, S.R.1    Creech, E.A.2    Schaffer, A.V.3    Martin, L.L.4    Rakhit, A.5    Douglas, F.L.6
  • 284
    • 84884729409 scopus 로고    scopus 로고
    • Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption
    • Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, et al. (2013). Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption. Toxicol Appl Pharmacol 272: 879-887.
    • (2013) Toxicol Appl Pharmacol , vol.272 , pp. 879-887
    • Srivastava, R.K.1    Li, C.2    Chaudhary, S.C.3    Ballestas, M.E.4    Elmets, C.A.5    Robbins, D.J.6
  • 286
    • 79955689812 scopus 로고    scopus 로고
    • Non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine inhibit cytochrome c oxidase in mouse brain regions
    • Streck EL, Ferreira GK, Scaini G, Rezin GT, Gonçalves CL, Jeremias IC, et al. (2011). Non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine inhibit cytochrome c oxidase in mouse brain regions. Neurochem Res 36: 962-966.
    • (2011) Neurochem Res , vol.36 , pp. 962-966
    • Streck, E.L.1    Ferreira, G.K.2    Scaini, G.3    Rezin, G.T.4    Gonçalves, C.L.5    Jeremias, I.C.6
  • 287
    • 84455173094 scopus 로고    scopus 로고
    • 4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells
    • Suaud L, Miller K, Panichelli AE, Randell RL, Marando CM, Rubenstein RC (2011). 4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells. J Biol Chem 286: 45083-45092.
    • (2011) J Biol Chem , vol.286 , pp. 45083-45092
    • Suaud, L.1    Miller, K.2    Panichelli, A.E.3    Randell, R.L.4    Marando, C.M.5    Rubenstein, R.C.6
  • 289
    • 84903461650 scopus 로고    scopus 로고
    • Glucosamine-induced Sp1 O-GlcNAcylation ameliorates hypoxia-induced SGLT dysfunction in primary cultured renal proximal tubule cells
    • Suh HN, Lee YJ, Kim MO, Ryu JM, Han HJ (2014). Glucosamine-induced Sp1 O-GlcNAcylation ameliorates hypoxia-induced SGLT dysfunction in primary cultured renal proximal tubule cells. J Cell Physiol 229: 1557-1568.
    • (2014) J Cell Physiol , vol.229 , pp. 1557-1568
    • Suh, H.N.1    Lee, Y.J.2    Kim, M.O.3    Ryu, J.M.4    Han, H.J.5
  • 290
    • 0036139688 scopus 로고    scopus 로고
    • Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections
    • Sulkowski MS, Thomas DL, Mehta SH, Chaisson RE, Moore RD (2002). Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections. Hepatology 35: 182-189.
    • (2002) Hepatology , vol.35 , pp. 182-189
    • Sulkowski, M.S.1    Thomas, D.L.2    Mehta, S.H.3    Chaisson, R.E.4    Moore, R.D.5
  • 291
    • 84873381429 scopus 로고    scopus 로고
    • Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin A as model compounds: an omics-guided approach
    • van Summeren A, Renes J, Lizarraga D, Bouwman FG, Noben JP, van Delft JH, et al. (2013). Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin A as model compounds: an omics-guided approach. OMICS 17: 71-83.
    • (2013) OMICS , vol.17 , pp. 71-83
    • van Summeren, A.1    Renes, J.2    Lizarraga, D.3    Bouwman, F.G.4    Noben, J.P.5    van Delft, J.H.6
  • 292
    • 84885096746 scopus 로고    scopus 로고
    • Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes
    • Szalowska E, Stoopen G, Groot MJ, Hendriksen PJ, Peijnenburg AA (2013). Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes. BMC Med Genomics 6: 39.
    • (2013) BMC Med Genomics , vol.6 , pp. 39
    • Szalowska, E.1    Stoopen, G.2    Groot, M.J.3    Hendriksen, P.J.4    Peijnenburg, A.A.5
  • 293
    • 0015156164 scopus 로고
    • Effect of tunicamycin on the synthesis of macromolecules in cultures of chick embryo fibroblasts infected with Newcastle disease virus
    • Takatsuki A, Tamura G (1971). Effect of tunicamycin on the synthesis of macromolecules in cultures of chick embryo fibroblasts infected with Newcastle disease virus. J Antibiot 24: 785-794.
    • (1971) J Antibiot , vol.24 , pp. 785-794
    • Takatsuki, A.1    Tamura, G.2
  • 295
    • 84930948378 scopus 로고    scopus 로고
    • The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice
    • Tanaka Y, Ishitsuka Y, Hayasaka M, Yamada Y, Miyata K, Endo M, et al. (2015). The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice. Pharmacol Res 99: 52-62.
    • (2015) Pharmacol Res , vol.99 , pp. 52-62
    • Tanaka, Y.1    Ishitsuka, Y.2    Hayasaka, M.3    Yamada, Y.4    Miyata, K.5    Endo, M.6
  • 298
    • 84883633521 scopus 로고    scopus 로고
    • Comparative analysis of ER stress response into HIV protease inhibitors: lopinavir but not darunavir induces potent ER stress response via ROS/JNK pathway
    • Taura M, Kariya R, Kudo E, Goto H, Iwawaki T, Amano M, et al. (2013). Comparative analysis of ER stress response into HIV protease inhibitors: lopinavir but not darunavir induces potent ER stress response via ROS/JNK pathway. Free Radic Biol Med 65: 778-788.
    • (2013) Free Radic Biol Med , vol.65 , pp. 778-788
    • Taura, M.1    Kariya, R.2    Kudo, E.3    Goto, H.4    Iwawaki, T.5    Amano, M.6
  • 299
    • 84887345283 scopus 로고    scopus 로고
    • Antipsychotic-induced insulin resistance and postprandial hormonal dysregulation independent of weight gain or psychiatric disease
    • Teff KL, Rickels MR, Grudziak J, Fuller C, Nguyen HL, Rickels K (2013). Antipsychotic-induced insulin resistance and postprandial hormonal dysregulation independent of weight gain or psychiatric disease. Diabetes 62: 3232-3240.
    • (2013) Diabetes , vol.62 , pp. 3232-3240
    • Teff, K.L.1    Rickels, M.R.2    Grudziak, J.3    Fuller, C.4    Nguyen, H.L.5    Rickels, K.6
  • 300
    • 68949103975 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism in the human gut wall
    • Thelen K, Dressman JB (2009). Cytochrome P450-mediated metabolism in the human gut wall. J Pharm Pharmacol 61: 541-558.
    • (2009) J Pharm Pharmacol , vol.61 , pp. 541-558
    • Thelen, K.1    Dressman, J.B.2
  • 301
    • 70349696241 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways
    • Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, et al. (2009). Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest 119: 2925-2941.
    • (2009) J Clin Invest , vol.119 , pp. 2925-2941
    • Timmins, J.M.1    Ozcan, L.2    Seimon, T.A.3    Li, G.4    Malagelada, C.5    Backs, J.6
  • 302
    • 0016757289 scopus 로고
    • Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomes
    • Tkacz JS, Lampen O (1975). Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomes. Biochem Biophys Res Commun 65: 248-257.
    • (1975) Biochem Biophys Res Commun , vol.65 , pp. 248-257
    • Tkacz, J.S.1    Lampen, O.2
  • 303
    • 84877153703 scopus 로고    scopus 로고
    • The emerging issue of cardiac dysfunction induced by antineoplastic angiogenesis inhibitors
    • Tocchetti CG, Gallucci G, Coppola C, Piscopo G, Cipresso C, Maurea C, et al. (2013). The emerging issue of cardiac dysfunction induced by antineoplastic angiogenesis inhibitors. Eur J Heart Fail 15: 482-489.
    • (2013) Eur J Heart Fail , vol.15 , pp. 482-489
    • Tocchetti, C.G.1    Gallucci, G.2    Coppola, C.3    Piscopo, G.4    Cipresso, C.5    Maurea, C.6
  • 304
    • 77953914488 scopus 로고    scopus 로고
    • Resveratrol protects against protease inhibitor-induced reactive oxygen species production, reticulum stress and lipid raft perturbation
    • Touzet O, Philips A (2010). Resveratrol protects against protease inhibitor-induced reactive oxygen species production, reticulum stress and lipid raft perturbation. AIDS 24: 1437-1447.
    • (2010) AIDS , vol.24 , pp. 1437-1447
    • Touzet, O.1    Philips, A.2
  • 306
    • 4544322635 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis
    • Tsutsumi S, Gotoh T, Tomisato W, Mima S, Hoshino T, Hwang HJ, et al. (2004). Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis. Cell Death Differ 11: 1009-1016.
    • (2004) Cell Death Differ , vol.11 , pp. 1009-1016
    • Tsutsumi, S.1    Gotoh, T.2    Tomisato, W.3    Mima, S.4    Hoshino, T.5    Hwang, H.J.6
  • 307
    • 0842266604 scopus 로고    scopus 로고
    • Oxidative protein folding in eukaryotes: mechanisms and consequences
    • Tu BP, Weissman JS (2004). Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol 164: 341-346.
    • (2004) J Cell Biol , vol.164 , pp. 341-346
    • Tu, B.P.1    Weissman, J.S.2
  • 310
    • 84924599479 scopus 로고    scopus 로고
    • Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC. complexes
    • Vineetha VP, Soumya RS, Raghu KG (2015). Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC. complexes. Eur J Pharmacol 754: 162-172.
    • (2015) Eur J Pharmacol , vol.754 , pp. 162-172
    • Vineetha, V.P.1    Soumya, R.S.2    Raghu, K.G.3
  • 311
    • 0037106461 scopus 로고    scopus 로고
    • Endoplasmic reticulum resident proteins of normal human dermal fibroblasts are the major targets for oxidative stress induced by hydrogen peroxide
    • van der Vlies D, Pap EH, Post JA, Celis JE, Wirtz KW (2002). Endoplasmic reticulum resident proteins of normal human dermal fibroblasts are the major targets for oxidative stress induced by hydrogen peroxide. Biochem J 366: 825-830.
    • (2002) Biochem J , vol.366 , pp. 825-830
    • van der Vlies, D.1    Pap, E.H.2    Post, J.A.3    Celis, J.E.4    Wirtz, K.W.5
  • 312
    • 0041761700 scopus 로고    scopus 로고
    • Oxidation of ER resident proteins upon oxidative stress: effects of altering cellular redox/antioxidant status and implications for protein maturation
    • van der Vlies D, Makkinje M, Jansens A, Braakman I, Verkleij AJ, Wirtz KW, et al. (2003). Oxidation of ER resident proteins upon oxidative stress: effects of altering cellular redox/antioxidant status and implications for protein maturation. Antioxid Redox Signal 5: 381-387.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 381-387
    • van der Vlies, D.1    Makkinje, M.2    Jansens, A.3    Braakman, I.4    Verkleij, A.J.5    Wirtz, K.W.6
  • 313
    • 82955184551 scopus 로고    scopus 로고
    • NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies
    • Wallace JL (2012). NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies. Br J Pharmacol 165: 67-74.
    • (2012) Br J Pharmacol , vol.165 , pp. 67-74
    • Wallace, J.L.1
  • 314
    • 33644871342 scopus 로고    scopus 로고
    • Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress
    • Wang X, Thomas B, Sachdeva R, Arterburn L, Frye L, Hatcher PG, et al. (2006). Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress. Proc Natl Acad Sci USA 103: 3604-3609.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3604-3609
    • Wang, X.1    Thomas, B.2    Sachdeva, R.3    Arterburn, L.4    Frye, L.5    Hatcher, P.G.6
  • 315
    • 84875202553 scopus 로고    scopus 로고
    • A unifying ontology to integrate histological and clinical observations for drug-induced liver injury
    • Wang Y, Lin Z, Liu Z, Harris S, Kelly R, Zhang J, et al. (2013a). A unifying ontology to integrate histological and clinical observations for drug-induced liver injury. Am J Pathol 182: 1180-1187.
    • (2013) Am J Pathol , vol.182 , pp. 1180-1187
    • Wang, Y.1    Lin, Z.2    Liu, Z.3    Harris, S.4    Kelly, R.5    Zhang, J.6
  • 316
    • 84874484624 scopus 로고    scopus 로고
    • The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice
    • Wang Y, Zhang L, Wu X, Gurley EC, Kennedy E, Hylemon PB, et al. (2013b). The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice. Hepatology 57: 1005-1016.
    • (2013) Hepatology , vol.57 , pp. 1005-1016
    • Wang, Y.1    Zhang, L.2    Wu, X.3    Gurley, E.C.4    Kennedy, E.5    Hylemon, P.B.6
  • 317
    • 84899496485 scopus 로고    scopus 로고
    • Deletion of p18(INK4c) aggravates cisplatin-induced acute kidney injury
    • Wang L, Chen W, Zhang Y, Liu C, Yuan L, Fu L, et al. (2014). Deletion of p18(INK4c) aggravates cisplatin-induced acute kidney injury. Int J Mol Med 33: 1621-1626.
    • (2014) Int J Mol Med , vol.33 , pp. 1621-1626
    • Wang, L.1    Chen, W.2    Zhang, Y.3    Liu, C.4    Yuan, L.5    Fu, L.6
  • 318
    • 33745607004 scopus 로고    scopus 로고
    • Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial
    • Watkins PB, Kaplowitz N, Slattery JT, Colonese CR, Colucci SV, Stewart PW, et al. (2006). Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA 296: 87-93.
    • (2006) JAMA , vol.296 , pp. 87-93
    • Watkins, P.B.1    Kaplowitz, N.2    Slattery, J.T.3    Colonese, C.R.4    Colucci, S.V.5    Stewart, P.W.6
  • 319
    • 0026588973 scopus 로고
    • N-acetyl-p-benzoquinone imine-induced protein thiol modification in isolated rat hepatocytes
    • Weis M, Morgenstern R, Cotgreave IA, Nelson SD, Moldeus P (1992). N-acetyl-p-benzoquinone imine-induced protein thiol modification in isolated rat hepatocytes. Biochem Pharmacol 43: 1493-1505.
    • (1992) Biochem Pharmacol , vol.43 , pp. 1493-1505
    • Weis, M.1    Morgenstern, R.2    Cotgreave, I.A.3    Nelson, S.D.4    Moldeus, P.5
  • 320
    • 84953352486 scopus 로고    scopus 로고
    • Efavirenz causes oxidative stress, endoplasmic reticulum stress, and autophagy in endothelial cells
    • Weiß M, Kost B, Renner-Müller I, Wolf E, Mylonas I, Brüning A (2015). Efavirenz causes oxidative stress, endoplasmic reticulum stress, and autophagy in endothelial cells. Cardiovasc Toxicol. doi:10.1007/s12012-015-9314-2.
    • (2015) Cardiovasc Toxicol
    • Weiß, M.1    Kost, B.2    Renner-Müller, I.3    Wolf, E.4    Mylonas, I.5    Brüning, A.6
  • 321
    • 84893963656 scopus 로고    scopus 로고
    • Arsenic trioxide induces unfolded protein response in vascular endothelial cells
    • Weng CY, Chiou SY, Wang L, Kou MC, Wang YJ, Wu  MJ (2014). Arsenic trioxide induces unfolded protein response in vascular endothelial cells. Arch Toxicol 88: 213-226.
    • (2014) Arch Toxicol , vol.88 , pp. 213-226
    • Weng, C.Y.1    Chiou, S.Y.2    Wang, L.3    Kou, M.C.4    Wang, Y.J.5    Wu, M.J.6
  • 322
    • 0035014266 scopus 로고    scopus 로고
    • Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
    • Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, et al. (2001). Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 107: 1263-1273.
    • (2001) J Clin Invest , vol.107 , pp. 1263-1273
    • Werstuck, G.H.1    Lentz, S.R.2    Dayal, S.3    Hossain, G.S.4    Sood, S.K.5    Shi, Y.Y.6
  • 323
    • 0035880237 scopus 로고    scopus 로고
    • Sudden death among patients with acute promyelocytic leukemia treated with arsenic trioxide
    • Westervelt P, Brown RA, Adkins DR, Khoury H, Curtin P, Hurd D, et al. (2001). Sudden death among patients with acute promyelocytic leukemia treated with arsenic trioxide. Blood 98: 266-271.
    • (2001) Blood , vol.98 , pp. 266-271
    • Westervelt, P.1    Brown, R.A.2    Adkins, D.R.3    Khoury, H.4    Curtin, P.5    Hurd, D.6
  • 326
    • 72249086559 scopus 로고    scopus 로고
    • HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells
    • Wu X, Sun L, Zha W, Studer E, Gurley E, Chen L, et al. (2010). HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells. Gastroenterology 138: 197-209.
    • (2010) Gastroenterology , vol.138 , pp. 197-209
    • Wu, X.1    Sun, L.2    Zha, W.3    Studer, E.4    Gurley, E.5    Chen, L.6
  • 327
    • 84871895377 scopus 로고    scopus 로고
    • Mechanisms of cyclosporine-induced renal cell apoptosis: a systematic review
    • Xiao Z, Shan J, Li C, Luo L, Lu J, Li S, et al. (2013). Mechanisms of cyclosporine-induced renal cell apoptosis: a systematic review. Am J Nephrol 37: 30-40.
    • (2013) Am J Nephrol , vol.37 , pp. 30-40
    • Xiao, Z.1    Shan, J.2    Li, C.3    Luo, L.4    Lu, J.5    Li, S.6
  • 328
    • 0036725164 scopus 로고    scopus 로고
    • Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation
    • Xie Q, Khaoustov VI, Chung CC, Sohn J, Krishnan B, Lewis DE, et al. (2002). Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology 36: 592-601.
    • (2002) Hepatology , vol.36 , pp. 592-601
    • Xie, Q.1    Khaoustov, V.I.2    Chung, C.C.3    Sohn, J.4    Krishnan, B.5    Lewis, D.E.6
  • 329
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: cell life and death decisions
    • Xu C, Bailly-Maitre B, Reed JC (2005). Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115: 2656-2664.
    • (2005) J Clin Invest , vol.115 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 331
    • 77956232915 scopus 로고    scopus 로고
    • Induction of liver steatosis and lipid droplet formation in ATF6α-knockout mice burdened with pharmacological endoplasmic reticulum stress
    • Yamamoto K, Takahara K, Oyadomari S, Okada T, Sato T, Harada A, et al. (2010). Induction of liver steatosis and lipid droplet formation in ATF6α-knockout mice burdened with pharmacological endoplasmic reticulum stress. Mol Biol Cell 21: 2975-2986.
    • (2010) Mol Biol Cell , vol.21 , pp. 2975-2986
    • Yamamoto, K.1    Takahara, K.2    Oyadomari, S.3    Okada, T.4    Sato, T.5    Harada, A.6
  • 332
    • 84866026116 scopus 로고    scopus 로고
    • Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway
    • Yen YP, Tsai KS, Chen YW, Huang CF, Yang RS, Liu SH (2012). Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway. Arch Toxicol 86: 923-933.
    • (2012) Arch Toxicol , vol.86 , pp. 923-933
    • Yen, Y.P.1    Tsai, K.S.2    Chen, Y.W.3    Huang, C.F.4    Yang, R.S.5    Liu, S.H.6
  • 333
    • 81855172494 scopus 로고    scopus 로고
    • In vitro and in vivo models of drug ototoxicity: studying the mechanisms of a clinical problem
    • Yorgason JG, Luxford W, Kalinec F (2011). In vitro and in vivo models of drug ototoxicity: studying the mechanisms of a clinical problem. Expert Opin Drug Metab Toxicol 7: 1521-1534.
    • (2011) Expert Opin Drug Metab Toxicol , vol.7 , pp. 1521-1534
    • Yorgason, J.G.1    Luxford, W.2    Kalinec, F.3
  • 334
    • 3242761550 scopus 로고    scopus 로고
    • Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review
    • Yoshida T, Yamauchi H, Fan Sun G (2004). Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review. Toxicol Appl Pharmacol 198: 243-252.
    • (2004) Toxicol Appl Pharmacol , vol.198 , pp. 243-252
    • Yoshida, T.1    Yamauchi, H.2    Fan Sun, G.3
  • 335
    • 77949366398 scopus 로고    scopus 로고
    • Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages
    • Zha W, Liang G, Xiao J, Studer EJ, Hylemon PB, Pandak WM, et al. (2010). Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages. PLoS ONE 5: e9069.
    • (2010) PLoS ONE , vol.5
    • Zha, W.1    Liang, G.2    Xiao, J.3    Studer, E.J.4    Hylemon, P.B.5    Pandak, W.M.6
  • 336
    • 84875357899 scopus 로고    scopus 로고
    • HIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytes
    • Zha BS, Wan X, Zhang X, Zha W, Zhou J, Wabitsch M, et al. (2013). HIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytes. PLoS ONE 8: e59514.
    • (2013) PLoS ONE , vol.8
    • Zha, B.S.1    Wan, X.2    Zhang, X.3    Zha, W.4    Zhou, J.5    Wabitsch, M.6
  • 337
    • 77950826446 scopus 로고    scopus 로고
    • Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML
    • Zhang XW, Yan XJ, Zhou ZR, Yang FF, Wu ZY, Sun HB, et al. (2010). Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science 328: 240-243.
    • (2010) Science , vol.328 , pp. 240-243
    • Zhang, X.W.1    Yan, X.J.2    Zhou, Z.R.3    Yang, F.F.4    Wu, Z.Y.5    Sun, H.B.6
  • 338
    • 79953794116 scopus 로고    scopus 로고
    • The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis
    • Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, Wang G, et al. (2011). The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. EMBO J 30: 1357-1375.
    • (2011) EMBO J , vol.30 , pp. 1357-1375
    • Zhang, K.1    Wang, S.2    Malhotra, J.3    Hassler, J.R.4    Back, S.H.5    Wang, G.6
  • 339
    • 84901286029 scopus 로고    scopus 로고
    • Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice
    • Zhao H, Wu QQ, Cao LF, Qing HY, Zhang C, Chen YH, et al. (2014a). Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice. PLoS ONE 9: e97266.
    • (2014) PLoS ONE , vol.9
    • Zhao, H.1    Wu, Q.Q.2    Cao, L.F.3    Qing, H.Y.4    Zhang, C.5    Chen, Y.H.6
  • 340
    • 84911164083 scopus 로고    scopus 로고
    • Phenylbutyric acid inhibits epithelial-mesenchymal transition during bleomycin-induced lung fibrosis
    • Zhao H, Qin HY, Cao LF, Chen YH, Tan ZX, Zhang C, et al. (2014b). Phenylbutyric acid inhibits epithelial-mesenchymal transition during bleomycin-induced lung fibrosis. Toxicol Lett 232: 213-220.
    • (2014) Toxicol Lett , vol.232 , pp. 213-220
    • Zhao, H.1    Qin, H.Y.2    Cao, L.F.3    Chen, Y.H.4    Tan, Z.X.5    Zhang, C.6
  • 341
    • 84877620041 scopus 로고    scopus 로고
    • CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition
    • Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, et al. (2013). CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition. Transplantation 95: 821-827.
    • (2013) Transplantation , vol.95 , pp. 821-827
    • Zheng, S.1    Tasnif, Y.2    Hebert, M.F.3    Davis, C.L.4    Shitara, Y.5    Calamia, J.C.6
  • 342
    • 79251517392 scopus 로고    scopus 로고
    • HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells
    • Zhou H (2011). HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells. Methods Enzymol 490: 107-119.
    • (2011) Methods Enzymol , vol.490 , pp. 107-119
    • Zhou, H.1
  • 343
    • 0029658060 scopus 로고    scopus 로고
    • 14C]acetaminophen to mouse hepatic microsomal proteins: the specific binding to calreticulin and the two forms of the thiol:protein disulfide oxidoreductases
    • 14C]acetaminophen to mouse hepatic microsomal proteins: the specific binding to calreticulin and the two forms of the thiol:protein disulfide oxidoreductases. Chem Res Toxicol 9: 1176-1182.
    • (1996) Chem Res Toxicol , vol.9 , pp. 1176-1182
    • Zhou, L.1    McKenzie, B.A.2    Eccleston, E.D.3    Srivastava, S.P.4    Chen, N.5    Erickson, R.R.6
  • 344
    • 23944491920 scopus 로고    scopus 로고
    • HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease
    • Zhou H, Pandak WM Jr, Lyall V, Natarajan R, Hylemon PB (2005). HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease. Mol Pharmacol 68: 690-700.
    • (2005) Mol Pharmacol , vol.68 , pp. 690-700
    • Zhou, H.1    Pandak, W.M.2    Lyall, V.3    Natarajan, R.4    Hylemon, P.B.5
  • 345
    • 0032054744 scopus 로고    scopus 로고
    • CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
    • Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, et al. (1998). CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12: 982-995.
    • (1998) Genes Dev , vol.12 , pp. 982-995
    • Zinszner, H.1    Kuroda, M.2    Wang, X.3    Batchvarova, N.4    Lightfoot, R.T.5    Remotti, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.