-
1
-
-
28444474185
-
The gene disrupted in Marinesco-Sjogren syndrome encodes SIL1, an HSPA5 cochaperone
-
Anttonen AK, Mahjneh I, Hamalainen RH, Lagier-Tourenne C, Kopra O, Waris L, Anttonen M, Joensuu T, Kalimo H, Paetau A, Tranebjaerg L, Chaigne D, Koenig M, Eeg-Olofsson O, Udd B, Somer M, Somer H, and Lehesjoki AE. The gene disrupted in Marinesco-Sjogren syndrome encodes SIL1, an HSPA5 cochaperone. Nat Genet 37: 1309-1311, 2005.
-
(2005)
Nat Genet
, vol.37
, pp. 1309-1311
-
-
Anttonen, A.K.1
Mahjneh, I.2
Hamalainen, R.H.3
Lagier-Tourenne, C.4
Kopra, O.5
Waris, L.6
Anttonen, M.7
Joensuu, T.8
Kalimo, H.9
Paetau, A.10
Tranebjaerg, L.11
Chaigne, D.12
Koenig, M.13
Eeg-Olofsson, O.14
Udd, B.15
Somer, M.16
Somer, H.17
Lehesjoki, A.E.18
-
2
-
-
4344575903
-
Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
-
Austin RC, Lentz SR, and Werstuck GH. Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death Differ 11: suppl 1, S56-S64, 2004.
-
(2004)
Cell Death Differ
, vol.11
, Issue.SUPPL. 1
-
-
Austin, R.C.1
Lentz, S.R.2
Werstuck, G.H.3
-
3
-
-
0026091179
-
Identification of a protein required for disulfide bond formation in vivo
-
Bardwell JC, McGovern K, and Beckwith J. Identification of a protein required for disulfide bond formation in vivo. Cell 67: 581-589, 1991.
-
(1991)
Cell
, vol.67
, pp. 581-589
-
-
Bardwell, J.C.1
McGovern, K.2
Beckwith, J.3
-
4
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence NF, Sampat RM, and Kopito RR. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292: 1552-1555, 2001.
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
5
-
-
0036877142
-
The endoplasmic reticulum: A multifunctional signaling organelle
-
Berridge MJ. The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium 32: 235-249, 2002.
-
(2002)
Cell Calcium
, vol.32
, pp. 235-249
-
-
Berridge, M.J.1
-
6
-
-
0038125598
-
Calcium signalling: Dynamics, homeostasis and remodelling
-
Berridge MJ, Bootman MD, and Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4: 517-529, 2003.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 517-529
-
-
Berridge, M.J.1
Bootman, M.D.2
Roderick, H.L.3
-
7
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti A, Wang X, Novoa I, Jungreis R, Schlessinger K, Cho JH, West AB, and Ron D. Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest 107: 585-593, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
West, A.B.7
Ron, D.8
-
9
-
-
0346487261
-
Role of calcium and superoxide dismutase in sensitizing mitochondria to peroxynitrite-induced permeability transition
-
Brookes PS, and Darley-Usmar VM. Role of calcium and superoxide dismutase in sensitizing mitochondria to peroxynitrite-induced permeability transition. Am J Physiol Heart Circ Physiol 286: H39-H46, 2004.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
-
-
Brookes, P.S.1
Darley-Usmar, V.M.2
-
10
-
-
0034681340
-
ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum
-
Cabibbo A, Pagani M, Fabbri M, Rocchi M, Farmery MR, Bulleid NJ, and Sitia R. ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum. J Biol Chem 275: 4827-4833, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 4827-4833
-
-
Cabibbo, A.1
Pagani, M.2
Fabbri, M.3
Rocchi, M.4
Farmery, M.R.5
Bulleid, N.J.6
Sitia, R.7
-
11
-
-
0034634281
-
Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
-
Cai H, and Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87: 840-844, 2000.
-
(2000)
Circ Res
, vol.87
, pp. 840-844
-
-
Cai, H.1
Harrison, D.G.2
-
12
-
-
0034304391
-
NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: The role of oxidant/antioxidant balance
-
Calabrese V, Bates TE, and Stella AM. NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. Neurochem Res 25: 1315-1341, 2000.
-
(2000)
Neurochem Res
, vol.25
, pp. 1315-1341
-
-
Calabrese, V.1
Bates, T.E.2
Stella, A.M.3
-
13
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, Clark SG, and Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96, 2002.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
14
-
-
0030765707
-
Cysteine and glutathione secretion in response to protein disulfide bond formation in the ER
-
Carelli S, Ceriotti A, Cabibbo A, Fassina G, Ruvo M, and Sitia R. Cysteine and glutathione secretion in response to protein disulfide bond formation in the ER. Science 277: 1681-1684, 1997.
-
(1997)
Science
, vol.277
, pp. 1681-1684
-
-
Carelli, S.1
Ceriotti, A.2
Cabibbo, A.3
Fassina, G.4
Ruvo, M.5
Sitia, R.6
-
15
-
-
4143087106
-
-
Chae HJ, Kim HR, Xu C, Bailly-Maitre B, Krajewska M, Krajewski S, Banares S, Cui J, Digicaylioglu M, Ke N, Kitada S, Monosov E, Thomas M, Kress CL, Babendure JR, Tsien RY, Lipton SA, and Reed JC. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell 15: 355-366, 2004.
-
Chae HJ, Kim HR, Xu C, Bailly-Maitre B, Krajewska M, Krajewski S, Banares S, Cui J, Digicaylioglu M, Ke N, Kitada S, Monosov E, Thomas M, Kress CL, Babendure JR, Tsien RY, Lipton SA, and Reed JC. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell 15: 355-366, 2004.
-
-
-
-
16
-
-
4544249202
-
Glutathione is required to regulate the formation of native disulfide bonds within proteins entering the secretory pathway
-
Chakravarthi S, and Bulleid NJ. Glutathione is required to regulate the formation of native disulfide bonds within proteins entering the secretory pathway. J Biol Chem 279: 39872-39879, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 39872-39879
-
-
Chakravarthi, S.1
Bulleid, N.J.2
-
17
-
-
33745242294
-
Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: A role for the IAPs
-
Cheung HH, Lynn Kelly N, Liston P, and Korneluk RG. Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs. Exp Cell Res 312: 2347-2357, 2006.
-
(2006)
Exp Cell Res
, vol.312
, pp. 2347-2357
-
-
Cheung, H.H.1
Lynn Kelly, N.2
Liston, P.3
Korneluk, R.G.4
-
18
-
-
4444237848
-
Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology
-
Conn KJ, Gao W, McKee A, Lan MS, Ullman MD, Eisenhauer PB, Fine RE, and Wells JM. Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology. Brain Res 1022: 164-172, 2004.
-
(2004)
Brain Res
, vol.1022
, pp. 164-172
-
-
Conn, K.J.1
Gao, W.2
McKee, A.3
Lan, M.S.4
Ullman, M.D.5
Eisenhauer, P.B.6
Fine, R.E.7
Wells, J.M.8
-
19
-
-
0030297537
-
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response
-
Cox JS, and Walter P. A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 87: 391-404, 1996.
-
(1996)
Cell
, vol.87
, pp. 391-404
-
-
Cox, J.S.1
Walter, P.2
-
20
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, and Walter P. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A 102: 18773-18784, 2005.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
21
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, and Diehl JA. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 23: 7198-7209, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
22
-
-
0033163758
-
Competition between glutathione and protein thiols for disulphide-bond formation
-
Cuozzo JW, and Kaiser CA. Competition between glutathione and protein thiols for disulphide-bond formation. Nat Cell Biol 1: 130-135, 1999.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 130-135
-
-
Cuozzo, J.W.1
Kaiser, C.A.2
-
23
-
-
20344392461
-
Caspases-2, -3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells
-
Dahmer MK. Caspases-2, -3, and -7 are involved in thapsigargin-induced apoptosis of SH-SY5Y neuroblastoma cells. J Neurosci Res 80: 576-583, 2005.
-
(2005)
J Neurosci Res
, vol.80
, pp. 576-583
-
-
Dahmer, M.K.1
-
24
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
-
Delepine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, and Julier C. EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 25: 406-409, 2000.
-
(2000)
Nat Genet
, vol.25
, pp. 406-409
-
-
Delepine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Lathrop, G.M.5
Julier, C.6
-
25
-
-
33645124763
-
Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism
-
Di Sano F, Ferraro E, Tufi R, Achsel T, Piacentini M, and Cecconi F. Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem 281: 2693-2700, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 2693-2700
-
-
Di Sano, F.1
Ferraro, E.2
Tufi, R.3
Achsel, T.4
Piacentini, M.5
Cecconi, F.6
-
26
-
-
33846080531
-
Oxidative stress mediates tau-induced neurodegeneration in Drosophila
-
Dias-Santagata D, Fulga TA, Duttaroy A, and Feany MB. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. J Clin Invest 117: 236-245, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 236-245
-
-
Dias-Santagata, D.1
Fulga, T.A.2
Duttaroy, A.3
Feany, M.B.4
-
27
-
-
0041324740
-
Effects of EGb 761 Ginkgo biloba extract on mitochondrial function and oxidative stress
-
Eckert A, Keil U, Kressmann S, Schindowski K, Leutner S, Leutz S, and Muller WE. Effects of EGb 761 Ginkgo biloba extract on mitochondrial function and oxidative stress. Pharmacopsychiatry 36 suppl 1: S15-S23, 2003.
-
(2003)
Pharmacopsychiatry
, vol.36
, Issue.SUPPL. 1
-
-
Eckert, A.1
Keil, U.2
Kressmann, S.3
Schindowski, K.4
Leutner, S.5
Leutz, S.6
Muller, W.E.7
-
28
-
-
0028828942
-
Hydrogen peroxide stimulates the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum
-
Favero TG, Zable AC, and Abramson JJ. Hydrogen peroxide stimulates the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. J Biol Chem 270: 25557-25563, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 25557-25563
-
-
Favero, T.G.1
Zable, A.C.2
Abramson, J.J.3
-
29
-
-
0042972934
-
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages
-
Feng B, Yao PM, Li Y, Devlin CM, Zhang D, Harding HP, Sweeney M, Rong JX, Kuriakose G, Fisher EA, Marks AR, Ron D, and Tabas, I. The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages. Nat Cell Biol 5: 781-792, 2003.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 781-792
-
-
Feng, B.1
Yao, P.M.2
Li, Y.3
Devlin, C.M.4
Zhang, D.5
Harding, H.P.6
Sweeney, M.7
Rong, J.X.8
Kuriakose, G.9
Fisher, E.A.10
Marks, A.R.11
Ron, D.12
Tabas, I.13
-
30
-
-
2442761708
-
The protein disulphide-isomerase family: Unravelling a string of folds
-
Ferrari DM, and Soling HD. The protein disulphide-isomerase family: unravelling a string of folds. Biochem J 339: 1-10, 1999.
-
(1999)
Biochem J
, vol.339
, pp. 1-10
-
-
Ferrari, D.M.1
Soling, H.D.2
-
31
-
-
0036139524
-
Reactive oxygen species and signal transduction
-
Finkel T. Reactive oxygen species and signal transduction. IUBMB Life 52: 3-6, 2001.
-
(2001)
IUBMB Life
, vol.52
, pp. 3-6
-
-
Finkel, T.1
-
32
-
-
0036294646
-
Human caspase 12 has acquired deleterious mutations
-
Fischer H, Koenig U, Eckhart L, and Tschachler E. Human caspase 12 has acquired deleterious mutations. Biochem Biophys Res Commun 293: 722-726, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 722-726
-
-
Fischer, H.1
Koenig, U.2
Eckhart, L.3
Tschachler, E.4
-
34
-
-
0031609760
-
The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum
-
Frand AR, and Kaiser CA. The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum. Mol Cell 1: 161-170, 1998.
-
(1998)
Mol Cell
, vol.1
, pp. 161-170
-
-
Frand, A.R.1
Kaiser, C.A.2
-
35
-
-
0034494605
-
Two pairs of conserved cysteines are required for the oxidative activity of Ero1p in protein disulfide bond formation in the endoplasmic reticulum
-
Frand AR, and Kaiser CA. Two pairs of conserved cysteines are required for the oxidative activity of Ero1p in protein disulfide bond formation in the endoplasmic reticulum. Mol Biol Cell 11: 2833-2843, 2000.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 2833-2843
-
-
Frand, A.R.1
Kaiser, C.A.2
-
36
-
-
0037517089
-
The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lalpha
-
Gess B, Hofbauer KH, Wenger RH, Lohaus C, Meyer HE, and Kurtz A. The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lalpha. Eur J Biochem 270: 2228-2235, 2003.
-
(2003)
Eur J Biochem
, vol.270
, pp. 2228-2235
-
-
Gess, B.1
Hofbauer, K.H.2
Wenger, R.H.3
Lohaus, C.4
Meyer, H.E.5
Kurtz, A.6
-
38
-
-
33750902737
-
The endoplasmic reticulum: Folding, calcium homeostasis, signaling, and redox control
-
Gorlach A, Klappa P, and Kietzmann T. The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid Redox Signal 8: 1391-1418, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1391-1418
-
-
Gorlach, A.1
Klappa, P.2
Kietzmann, T.3
-
39
-
-
33645567816
-
Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions
-
Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, and Tall AR. Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions. Cell Metab 3: 257-266, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 257-266
-
-
Han, S.1
Liang, C.P.2
DeVries-Seimon, T.3
Ranalletta, M.4
Welch, C.L.5
Collins-Fletcher, K.6
Accili, D.7
Tabas, I.8
Tall, A.R.9
-
40
-
-
0036437307
-
Transcriptional and translational control in the mammalian unfolded protein response
-
Harding HP, Calfon M, Urano F, Novoa I, and Ron D. Transcriptional and translational control in the mammalian unfolded protein response. Annu Rev Cell Dev Biol 18: 575-599, 2002.
-
(2002)
Annu Rev Cell Dev Biol
, vol.18
, pp. 575-599
-
-
Harding, H.P.1
Calfon, M.2
Urano, F.3
Novoa, I.4
Ron, D.5
-
41
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, and Ron D. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6: 1099-1108, 2000.
-
(2000)
Mol Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
42
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding HP, Zhang Y, Bertolotti A, Zeng H, and Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 5: 897-904, 2000.
-
(2000)
Mol Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
43
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding HP, Zhang Y, and Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274, 1999.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
44
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, Stojdl DF, Bell JC, Hettmann T, Leiden JM, and Ron D. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 11: 619-633, 2003.
-
(2003)
Mol Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
45
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
Haze K, Yoshida H, Yanagi H, Yura T, and Mori K. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 10: 3787-3799, 1999.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
46
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, and Korsmeyer SJ. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science 312: 572-576, 2006.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
47
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
-
Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, Tsujimoto Y, and Tohyama M. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol 165: 347-356, 2004.
-
(2004)
J Cell Biol
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
Tsujimoto, Y.11
Tohyama, M.12
-
48
-
-
0035107609
-
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
-
Hofmann MA, Lalla E, Lu Y, Gleason MR, Wolf BM, Tanji N, Ferran LJ Jr, Kohl B, Rao V, Kisiel W, Stern DM, and Schmidt AM. Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model. J Clin Invest 107: 675-683, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 675-683
-
-
Hofmann, M.A.1
Lalla, E.2
Lu, Y.3
Gleason, M.R.4
Wolf, B.M.5
Tanji, N.6
Ferran Jr, L.J.7
Kohl, B.8
Rao, V.9
Kisiel, W.10
Stern, D.M.11
Schmidt, A.M.12
-
49
-
-
0038143287
-
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
-
Holtz WA, and O'Malley KL. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J Biol Chem 278: 19367-19377, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 19367-19377
-
-
Holtz, W.A.1
O'Malley, K.L.2
-
50
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
Houstis N, Rosen ED, and Lander ES. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440: 944-948, 2006.
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
51
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu P, Han Z, Couvillon AD, Kaufman RJ, and Exton JH. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol 26: 3071-3084, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
52
-
-
0035844038
-
Homocysteine thiolactone induces apoptotic DNA damage mediated by increased intracellular hydrogen peroxide and caspase 3 activation in HL-60 cells
-
Huang RF, Huang SM, Lin BS, Wei JS, and Liu TZ. Homocysteine thiolactone induces apoptotic DNA damage mediated by increased intracellular hydrogen peroxide and caspase 3 activation in HL-60 cells. Life Sci 68: 2799-2811, 2001.
-
(2001)
Life Sci
, vol.68
, pp. 2799-2811
-
-
Huang, R.F.1
Huang, S.M.2
Lin, B.S.3
Wei, J.S.4
Liu, T.Z.5
-
53
-
-
0026698060
-
Oxidized redox state of glutathione in the endoplasmic reticulum
-
Hwang C, Sinskey AJ, and Lodish HF. Oxidized redox state of glutathione in the endoplasmic reticulum. Science 257: 1496-1502, 1992.
-
(1992)
Science
, vol.257
, pp. 1496-1502
-
-
Hwang, C.1
Sinskey, A.J.2
Lodish, H.F.3
-
54
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, and Takahashi R. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105: 891-902, 2001.
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, R.6
-
55
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai Y, Soda M, and Takahashi R. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 275: 35661-35664, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
56
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, and Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 4: 321-329, 2003.
-
(2003)
Nat Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
Otipoby, K.L.4
Rajewsky, K.5
Glimcher, L.H.6
-
57
-
-
0037087782
-
Mitochondrial oxidative stress and cell death in astrocytes: Requirement for stored Ca2+ and sustained opening of the permeability transition pore
-
Jacobson J, and Duchen MR. Mitochondrial oxidative stress and cell death in astrocytes: requirement for stored Ca2+ and sustained opening of the permeability transition pore. J Cell Sci 115: 1175-1188, 2002.
-
(2002)
J Cell Sci
, vol.115
, pp. 1175-1188
-
-
Jacobson, J.1
Duchen, M.R.2
-
58
-
-
8844259529
-
Oxidative protein folding in the mammalian endoplasmic reticulum
-
Jessop CE, Chakravarthi S, Watkins RH, and Bulleid NJ. Oxidative protein folding in the mammalian endoplasmic reticulum. Biochem Soc Trans 32: 655-658, 2004.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 655-658
-
-
Jessop, C.E.1
Chakravarthi, S.2
Watkins, R.H.3
Bulleid, N.J.4
-
59
-
-
14844327760
-
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata H, Honda S, Maeda S, Chang L, Hirata H, and Karin M. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120: 649-661, 2005.
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
60
-
-
33846434443
-
Involvement of oxidative stress in the pathogenesis of diabetes
-
Kaneto H, Katakami N, Kawamori D, Miyatsuka T, Sakamoto K, Matsuoka TA, Matsuhisa M, and Yamasaki Y. Involvement of oxidative stress in the pathogenesis of diabetes. Antioxid Redox Signal 9: 355-366, 2007.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 355-366
-
-
Kaneto, H.1
Katakami, N.2
Kawamori, D.3
Miyatsuka, T.4
Sakamoto, K.5
Matsuoka, T.A.6
Matsuhisa, M.7
Yamasaki, Y.8
-
61
-
-
21544471229
-
Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes
-
Kaneto H, Matsuoka TA, Nakatani Y, Kawamori D, Miyatsuka T, Matsuhisa M, and Yamasaki Y. Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes. J Mol Med 83: 429-439, 2005.
-
(2005)
J Mol Med
, vol.83
, pp. 429-439
-
-
Kaneto, H.1
Matsuoka, T.A.2
Nakatani, Y.3
Kawamori, D.4
Miyatsuka, T.5
Matsuhisa, M.6
Yamasaki, Y.7
-
62
-
-
7044230885
-
Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide
-
Kaneto H, Nakatani Y, Miyatsuka T, Kawamori D, Matsuoka TA, Matsuhisa M, Kajimoto Y, Ichijo H, Yamasaki Y, and Hori M. Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide. Nat Med 10: 1128-1132, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 1128-1132
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Kawamori, D.4
Matsuoka, T.A.5
Matsuhisa, M.6
Kajimoto, Y.7
Ichijo, H.8
Yamasaki, Y.9
Hori, M.10
-
63
-
-
0036853914
-
Orchestrating the unfolded protein response in health and disease
-
Kaufman RJ. Orchestrating the unfolded protein response in health and disease. J Clin Invest 110: 1389-1398, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 1389-1398
-
-
Kaufman, R.J.1
-
64
-
-
1542316306
-
Regulation of mRNA translation by protein folding in the endoplasmic reticulum
-
Kaufman RJ. Regulation of mRNA translation by protein folding in the endoplasmic reticulum. Trends Biochem Sci 29: 152-158, 2004.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 152-158
-
-
Kaufman, R.J.1
-
65
-
-
10744227975
-
Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase
-
Kawamori D, Kajimoto Y, Kaneto H, Umayahara Y, Fujitani Y, Miyatsuka T, Watada H, Leibiger IB, Yamasaki Y, and Hori M. Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase. Diabetes 52: 2896-2904, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 2896-2904
-
-
Kawamori, D.1
Kajimoto, Y.2
Kaneto, H.3
Umayahara, Y.4
Fujitani, Y.5
Miyatsuka, T.6
Watada, H.7
Leibiger, I.B.8
Yamasaki, Y.9
Hori, M.10
-
66
-
-
33744741034
-
Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL
-
Kim SJ, Zhang Z, Hitomi E, Lee YC, and Mukherjee AB. Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. Hum Mol Genet 15: 1826-1834, 2006.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1826-1834
-
-
Kim, S.J.1
Zhang, Z.2
Hitomi, E.3
Lee, Y.C.4
Mukherjee, A.B.5
-
67
-
-
13944263299
-
OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes
-
Kondo S, Murakami T, Tatsumi K, Ogata M, Kanemoto S, Otori K, Iseki K, Wanaka A, and Imaizumi K. OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nat Cell Biol 7: 186-194, 2005.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 186-194
-
-
Kondo, S.1
Murakami, T.2
Tatsumi, K.3
Ogata, M.4
Kanemoto, S.5
Otori, K.6
Iseki, K.7
Wanaka, A.8
Imaizumi, K.9
-
68
-
-
33847188475
-
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer
-
Kondo S, Saito A, Hino S, Murakami T, Ogata M, Kanemoto S, Nara S, Yamashita A, Yoshinaga K, Hara H, and Imaizumi K. BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. Mol Cell Biol 27: 1716-1729, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1716-1729
-
-
Kondo, S.1
Saito, A.2
Hino, S.3
Murakami, T.4
Ogata, M.5
Kanemoto, S.6
Nara, S.7
Yamashita, A.8
Yoshinaga, K.9
Hara, H.10
Imaizumi, K.11
-
69
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee AH, Chu GC, Iwakoshi NN, and Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. Embo J 24: 4368-4380, 2005.
-
(2005)
Embo J
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
70
-
-
0037083755
-
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
-
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, and Kaufman RJ. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16: 452-466, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 452-466
-
-
Lee, K.1
Tirasophon, W.2
Shen, X.3
Michalak, M.4
Prywes, R.5
Okada, T.6
Yoshida, H.7
Mori, K.8
Kaufman, R.J.9
-
72
-
-
0027218501
-
Sequences required for thrombomodulin cofactor activity within the fourth epidermal growth factor-like domain of human thrombomodulin
-
Lentz SR, Chen Y, and Sadler JE. Sequences required for thrombomodulin cofactor activity within the fourth epidermal growth factor-like domain of human thrombomodulin. J Biol Chem 268: 15312-15317, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 15312-15317
-
-
Lentz, S.R.1
Chen, Y.2
Sadler, J.E.3
-
73
-
-
33646373219
-
Endoplasmic reticulum stress-induced apoptosis: Multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
-
Li J, Lee B, and Lee AS. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J Biol Chem 281: 7260-7270, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 7260-7270
-
-
Li, J.1
Lee, B.2
Lee, A.S.3
-
74
-
-
0033920261
-
ATF6 as a transcription activator of the endoplasmic reticulum stress element: Thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1
-
Li M, Baumeister P, Roy B, Phan T, Foti D, Luo S, and Lee AS. ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. Mol Cell Biol 20: 5096-5106, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5096-5106
-
-
Li, M.1
Baumeister, P.2
Roy, B.3
Phan, T.4
Foti, D.5
Luo, S.6
Lee, A.S.7
-
75
-
-
20444461628
-
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: Model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis
-
Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, and Tabas I. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. J Biol Chem 280: 21763-21772, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 21763-21772
-
-
Li, Y.1
Schwabe, R.F.2
DeVries-Seimon, T.3
Yao, P.M.4
Gerbod-Giannone, M.C.5
Tall, A.R.6
Davis, R.J.7
Flavell, R.8
Brenner, D.A.9
Tabas, I.10
-
76
-
-
33750472289
-
Characterization of erasin (UBXD2): A new ER protein that promotes ER-associated protein degradation
-
Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, and Monteiro MJ. Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation. J Cell Sci 119: 4011-4024, 2006.
-
(2006)
J Cell Sci
, vol.119
, pp. 4011-4024
-
-
Liang, J.1
Yin, C.2
Doong, H.3
Fang, S.4
Peterhoff, C.5
Nixon, R.A.6
Monteiro, M.J.7
-
78
-
-
0037131567
-
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
-
Liu Y, Fallon L, Lashuel HA, Liu Z, and Lansbury PT Jr. The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell 111: 209-218, 2002.
-
(2002)
Cell
, vol.111
, pp. 209-218
-
-
Liu, Y.1
Fallon, L.2
Lashuel, H.A.3
Liu, Z.4
Lansbury Jr., P.T.5
-
79
-
-
33748417012
-
Translocon pores in the endoplasmic reticulum are permeable to small anions
-
Lizak B, Czegle I, Csala M, Benedetti A, Mandl J, and Banhegyi G. Translocon pores in the endoplasmic reticulum are permeable to small anions. Am J Physiol Cell Physiol, 291 C511-C517, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Lizak, B.1
Czegle, I.2
Csala, M.3
Benedetti, A.4
Mandl, J.5
Banhegyi, G.6
-
80
-
-
0036314984
-
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
-
Ma Y, Brewer JW, Diehl JA, and Hendershot LM. Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J Mol Biol 318: 1351-1365, 2002.
-
(2002)
J Mol Biol
, vol.318
, pp. 1351-1365
-
-
Ma, Y.1
Brewer, J.W.2
Diehl, J.A.3
Hendershot, L.M.4
-
81
-
-
30944458057
-
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK
-
Marciniak SJ, Garcia-Bonilla L, Hu J, Harding HP, and Ron D. Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK. J Cell Biol 172: 201-209, 2006.
-
(2006)
J Cell Biol
, vol.172
, pp. 201-209
-
-
Marciniak, S.J.1
Garcia-Bonilla, L.2
Hu, J.3
Harding, H.P.4
Ron, D.5
-
82
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, and Ron D. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 18: 3066-3077, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
83
-
-
21244462014
-
-
Mathai JP, Germain M, and Shore GC. BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem 280: 23829-23836, 2005.
-
Mathai JP, Germain M, and Shore GC. BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem 280: 23829-23836, 2005.
-
-
-
-
84
-
-
33646365640
-
Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis
-
Mauro C, Crescenzi E, De Mattia R, Pacifico F, Mellone S, Salzano S, de Luca C, D'Adamio L, Palumbo G, Formisano S, Vito P, and Leonardi A. Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis. J Biol Chem 281: 2631-2638, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 2631-2638
-
-
Mauro, C.1
Crescenzi, E.2
De Mattia, R.3
Pacifico, F.4
Mellone, S.5
Salzano, S.6
de Luca, C.7
D'Adamio, L.8
Palumbo, G.9
Formisano, S.10
Vito, P.11
Leonardi, A.12
-
85
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough KD, Martindale JL, Klotz LO, Aw TY, and Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21: 1249-1259, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
86
-
-
0027305620
-
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
-
Mori K, Ma W, Gething MJ, and Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74: 743-756, 1993.
-
(1993)
Cell
, vol.74
, pp. 743-756
-
-
Mori, K.1
Ma, W.2
Gething, M.J.3
Sambrook, J.4
-
87
-
-
0034712734
-
mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response
-
Mori K, Ogawa N, Kawahara T, Yanagi H, and Yura T. mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response. Proc Natl Acad Sci U S A 97: 4660-4665, 2000.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4660-4665
-
-
Mori, K.1
Ogawa, N.2
Kawahara, T.3
Yanagi, H.4
Yura, T.5
-
88
-
-
0037072937
-
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
-
Morishima N, Nakanishi K, Takenouchi H, Shibata T, and Yasuhiko Y. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 34287-34294
-
-
Morishima, N.1
Nakanishi, K.2
Takenouchi, H.3
Shibata, T.4
Yasuhiko, Y.5
-
89
-
-
9644295726
-
Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis
-
Morishima N, Nakanishi K, Tsuchiya K, Shibata T, and Seiwa E. Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis. J Biol Chem 279: 50375-50381, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 50375-50381
-
-
Morishima, N.1
Nakanishi, K.2
Tsuchiya, K.3
Shibata, T.4
Seiwa, E.5
-
90
-
-
0031054643
-
Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins
-
Morris JA, Dorner AJ, Edwards CA, Hendershot LM, and Kaufman RJ. Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins. J Biol Chem 272: 4327-4334, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 4327-4334
-
-
Morris, J.A.1
Dorner, A.J.2
Edwards, C.A.3
Hendershot, L.M.4
Kaufman, R.J.5
-
91
-
-
20944445990
-
Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway
-
Nagamori I, Yabuta N, Fujii T, Tanaka H, Yomogida K, Nishimune Y, and Nojima H. Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway. Genes Cells 10: 575-594, 2005.
-
(2005)
Genes Cells
, vol.10
, pp. 575-594
-
-
Nagamori, I.1
Yabuta, N.2
Fujii, T.3
Tanaka, H.4
Yomogida, K.5
Nishimune, Y.6
Nojima, H.7
-
92
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T, and Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150: 887-894, 2000.
-
(2000)
J Cell Biol
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
93
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, and Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103, 2000.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
94
-
-
19944430402
-
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes
-
Nakatani Y, Kaneto H, Kawamori D, Yoshiuchi K, Hatazaki M, Matsuoka TA, Ozawa K, Ogawa S, Hori M, Yamasaki Y, and Matsuhisa M. Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J Biol Chem 280: 847-851, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 847-851
-
-
Nakatani, Y.1
Kaneto, H.2
Kawamori, D.3
Yoshiuchi, K.4
Hatazaki, M.5
Matsuoka, T.A.6
Ozawa, K.7
Ogawa, S.8
Hori, M.9
Yamasaki, Y.10
Matsuhisa, M.11
-
95
-
-
0037763721
-
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
-
Nguyen T, Sherratt PJ, and Pickett CB. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu Rev Pharmacol Toxicol 43: 233-260, 2003.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 233-260
-
-
Nguyen, T.1
Sherratt, P.J.2
Pickett, C.B.3
-
96
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, and Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16: 1345-1355, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
97
-
-
0033598996
-
A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response
-
Niwa M, Sidrauski C, Kaufman RJ, and Walter P. A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell 99: 691-702, 1999.
-
(1999)
Cell
, vol.99
, pp. 691-702
-
-
Niwa, M.1
Sidrauski, C.2
Kaufman, R.J.3
Walter, P.4
-
98
-
-
22844439230
-
Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function
-
Noguchi H, Nakai Y, Matsumoto S, Kawaguchi M, Ueda M, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Minami K, Masui Y, Futaki S, and Tanaka K. Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function. Am J Transplant 5: 1848-1855, 2005.
-
(2005)
Am J Transplant
, vol.5
, pp. 1848-1855
-
-
Noguchi, H.1
Nakai, Y.2
Matsumoto, S.3
Kawaguchi, M.4
Ueda, M.5
Okitsu, T.6
Iwanaga, Y.7
Yonekawa, Y.8
Nagata, H.9
Minami, K.10
Masui, Y.11
Futaki, S.12
Tanaka, K.13
-
99
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
Novoa I, Zeng H, Harding HP, and Ron D. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J Cell Biol 153: 1011-1022, 2001.
-
(2001)
J Cell Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
100
-
-
17144417669
-
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
-
Ohoka N, Yoshii S, Hattori T, Onozaki K, and Hayashi H. TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. Embo J 24: 1243-1255, 2005.
-
(2005)
Embo J
, vol.24
, pp. 1243-1255
-
-
Ohoka, N.1
Yoshii, S.2
Hattori, T.3
Onozaki, K.4
Hayashi, H.5
-
101
-
-
3042636436
-
JAB1 participates in unfolded protein responses by association and dissociation with IRE1
-
Oono K, Yoneda T, Manabe T, Yamagishi S, Matsuda S, Hitomi J, Miyata S, Mizuno T, Imaizumi K, Katayama T, and Tohyama, M. JAB1 participates in unfolded protein responses by association and dissociation with IRE1. Neurochem Int 45: 765-772, 2004.
-
(2004)
Neurochem Int
, vol.45
, pp. 765-772
-
-
Oono, K.1
Yoneda, T.2
Manabe, T.3
Yamagishi, S.4
Matsuda, S.5
Hitomi, J.6
Miyata, S.7
Mizuno, T.8
Imaizumi, K.9
Katayama, T.10
Tohyama, M.11
-
102
-
-
10744224825
-
Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron
-
Osaka H, Wang YL, Takada K, Takizawa S, Setsuie R, Li H, Sato Y, Nishikawa K, Sun YJ, Sakurai M, Harada T, Hara Y, Kimura I, Chiba S, Namikawa K, Kiyama H, Noda M, Aoki S, and Wada K. Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron. Hum Mol Genet 12: 1945-1958, 2003.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1945-1958
-
-
Osaka, H.1
Wang, Y.L.2
Takada, K.3
Takizawa, S.4
Setsuie, R.5
Li, H.6
Sato, Y.7
Nishikawa, K.8
Sun, Y.J.9
Sakurai, M.10
Harada, T.11
Hara, Y.12
Kimura, I.13
Chiba, S.14
Namikawa, K.15
Kiyama, H.16
Noda, M.17
Aoki, S.18
Wada, K.19
-
103
-
-
0345535616
-
Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells
-
Outinen PA, Sood SK, Pfeifer SI, Pamidi S, Podor TJ, Li J, Weitz JI, and Austin RC. Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells. Blood 94: 959-967, 1999.
-
(1999)
Blood
, vol.94
, pp. 959-967
-
-
Outinen, P.A.1
Sood, S.K.2
Pfeifer, S.I.3
Pamidi, S.4
Podor, T.J.5
Li, J.6
Weitz, J.I.7
Austin, R.C.8
-
104
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, and Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306: 457-461, 2004.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
105
-
-
0034604675
-
Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response
-
Pagani M, Fabbri M, Benedetti C, Fassio A, Pilati S, Bulleid NJ, Cabibbo A, and Sitia R. Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response. J Biol Chem 275: 23685-23692, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 23685-23692
-
-
Pagani, M.1
Fabbri, M.2
Benedetti, C.3
Fassio, A.4
Pilati, S.5
Bulleid, N.J.6
Cabibbo, A.7
Sitia, R.8
-
106
-
-
24644487812
-
Endoplasmic reticulum stress response and neurodegeneration
-
Paschen W, and Mengesdorf T. Endoplasmic reticulum stress response and neurodegeneration. Cell Calcium 38: 409-415, 2005.
-
(2005)
Cell Calcium
, vol.38
, pp. 409-415
-
-
Paschen, W.1
Mengesdorf, T.2
-
107
-
-
0035370949
-
Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals
-
Patil C, and Walter P. Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol 13: 349-355, 2001.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 349-355
-
-
Patil, C.1
Walter, P.2
-
108
-
-
0036176783
-
Plasma free fatty acid levels and the risk of ischemic heart disease in men: Prospective results from the Quebec Cardiovascular Study
-
Pirro M, Mauriege P, Tchernof A, Cantin B, Dagenais GR, Despres JP, and Lamarche B. Plasma free fatty acid levels and the risk of ischemic heart disease in men: prospective results from the Quebec Cardiovascular Study. Atherosclerosis 160: 377-384, 2002.
-
(2002)
Atherosclerosis
, vol.160
, pp. 377-384
-
-
Pirro, M.1
Mauriege, P.2
Tchernof, A.3
Cantin, B.4
Dagenais, G.R.5
Despres, J.P.6
Lamarche, B.7
-
109
-
-
0031610364
-
Ero1p: A novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum
-
Pollard MG, Travers KJ, and Weissman JS. Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Mol Cell 1: 171-182, 1998.
-
(1998)
Mol Cell
, vol.1
, pp. 171-182
-
-
Pollard, M.G.1
Travers, K.J.2
Weissman, J.S.3
-
110
-
-
0036315042
-
Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis
-
Raggo C, Rapin N, Stirling J, Gobeil P, Smith-Windsor E, O'Hare P, and Misra V. Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis. Mol Cell Biol 22: 5639-5649, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5639-5649
-
-
Raggo, C.1
Rapin, N.2
Stirling, J.3
Gobeil, P.4
Smith-Windsor, E.5
O'Hare, P.6
Misra, V.7
-
111
-
-
0034650851
-
An essential role in liver development for transcription factor XBP-1
-
Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, and Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes Dev 14: 152-157, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 152-157
-
-
Reimold, A.M.1
Etkin, A.2
Clauss, I.3
Perkins, A.4
Friend, D.S.5
Zhang, J.6
Horton, H.F.7
Scott, A.8
Orkin, S.H.9
Byrne, M.C.10
Grusby, M.J.11
Glimcher, L.H.12
-
112
-
-
0035913294
-
Plasma cell differentiation requires the transcription factor XBP-1
-
Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, and Glimcher LH. Plasma cell differentiation requires the transcription factor XBP-1. Nature 412: 300-307, 2001.
-
(2001)
Nature
, vol.412
, pp. 300-307
-
-
Reimold, A.M.1
Iwakoshi, N.N.2
Manis, J.3
Vallabhajosyula, P.4
Szomolanyi-Tsuda, E.5
Gravallese, E.M.6
Friend, D.7
Grusby, M.J.8
Alt, F.9
Glimcher, L.H.10
-
113
-
-
33750502270
-
Oxidative stress and impaired insulin secretion in type 2 diabetes
-
Robertson RP. Oxidative stress and impaired insulin secretion in type 2 diabetes. Curr Opin Pharmacol 6: 615-619, 2006.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 615-619
-
-
Robertson, R.P.1
-
114
-
-
0036856008
-
Translational control in the endoplasmic reticulum stress response
-
Ron D. Translational control in the endoplasmic reticulum stress response. J Clin Invest 110: 1383-1388, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 1383-1388
-
-
Ron, D.1
-
115
-
-
0026546365
-
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
-
Ron D, and Habener JF. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev 6: 439-453, 1992.
-
(1992)
Genes Dev
, vol.6
, pp. 439-453
-
-
Ron, D.1
Habener, J.F.2
-
116
-
-
0033552883
-
Atherosclerosis: An inflammatory disease
-
Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 340: 115-126, 1999.
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
117
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, Sadighi Akha AA, Raden D, and Kaufman RJ. Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol 4: e374, 2006.
-
(2006)
PLoS Biol
, vol.4
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
Wu, J.4
Li, J.5
Gunnison, K.M.6
Mori, K.7
Sadighi Akha, A.A.8
Raden, D.9
Kaufman, R.J.10
-
118
-
-
0032846416
-
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice
-
Saigoh K, Wang YL, Suh JG, Yamanishi T, Sakai Y, Kiyosawa H, Harada T, Ichihara N, Wakana S, Kikuchi T, and Wada K. Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice. Nat Genet 23: 47-51, 1999.
-
(1999)
Nat Genet
, vol.23
, pp. 47-51
-
-
Saigoh, K.1
Wang, Y.L.2
Suh, J.G.3
Yamanishi, T.4
Sakai, Y.5
Kiyosawa, H.6
Harada, T.7
Ichihara, N.8
Wakana, S.9
Kikuchi, T.10
Wada, K.11
-
119
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, and Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414: 799-806, 2001.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
120
-
-
33746361817
-
Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis
-
Scheuner D, Patel R, Wang F, Lee K, Kumar K, Wu J, Nilsson A, Karin M, and Kaufman RJ. Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis. J Biol Chem 281: 21458-21468, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 21458-21468
-
-
Scheuner, D.1
Patel, R.2
Wang, F.3
Lee, K.4
Kumar, K.5
Wu, J.6
Nilsson, A.7
Karin, M.8
Kaufman, R.J.9
-
121
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, and Kaufman RJ. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 7: 1165-1176, 2001.
-
(2001)
Mol Cell
, vol.7
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
122
-
-
22244446505
-
The mammalian unfolded protein response
-
Schroder M, and Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem 74: 739-789, 2005.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
123
-
-
0037418843
-
BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis
-
Scorrano L, Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T, and Korsmeyer SJ. BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. Science 300: 135-139, 2003.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
124
-
-
0347987853
-
Folding proteins in fatal ways
-
Selkoe DJ. Folding proteins in fatal ways. Nature 426: 900-904, 2003.
-
(2003)
Nature
, vol.426
, pp. 900-904
-
-
Selkoe, D.J.1
-
125
-
-
12844257546
-
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response
-
Shen J, Snapp EL, Lippincott-Schwartz J, and Prywes R. Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response. Mol Cell Biol 25: 921-932, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 921-932
-
-
Shen, J.1
Snapp, E.L.2
Lippincott-Schwartz, J.3
Prywes, R.4
-
126
-
-
18244405070
-
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
-
Shen X, Ellis RE, Lee K, Liu CY, Yang K, Solomon A, Yoshida H, Morimoto, R, Kurnit DM, Mori K, and Kaufman RJ. Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development. Cell 107: 893-903, 2001.
-
(2001)
Cell
, vol.107
, pp. 893-903
-
-
Shen, X.1
Ellis, R.E.2
Lee, K.3
Liu, C.Y.4
Yang, K.5
Solomon, A.6
Yoshida, H.7
Morimoto, R.8
Kurnit, D.M.9
Mori, K.10
Kaufman, R.J.11
-
127
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, Minoshima S, Shimizu N, Iwai K, Chiba T, Tanaka K, and Suzuki, T. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25: 302-305, 2000.
-
(2000)
Nat Genet
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
128
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 106: 171-176, 2000.
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
129
-
-
0030954870
-
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
-
Sidrauski C, and Walter P. The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90: 1031-1039, 1997.
-
(1997)
Cell
, vol.90
, pp. 1031-1039
-
-
Sidrauski, C.1
Walter, P.2
-
130
-
-
2542440824
-
Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line
-
Sigfrid LA, Cunningham JM, Beeharry N, Hakan Borg LA, Rosales Hernandez AL, Carlsson C, Bone AJ, and Green IC. Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line. J Mol Med 82: 325-335, 2004.
-
(2004)
J Mol Med
, vol.82
, pp. 325-335
-
-
Sigfrid, L.A.1
Cunningham, J.M.2
Beeharry, N.3
Hakan Borg, L.A.4
Rosales Hernandez, A.L.5
Carlsson, C.6
Bone, A.J.7
Green, I.C.8
-
131
-
-
0032940099
-
CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI
-
Sok J, Wang XZ, Batchvarova N, Kuroda M, Harding H, and Ron D. CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI. Mol Cell Biol 19: 495-504, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 495-504
-
-
Sok, J.1
Wang, X.Z.2
Batchvarova, N.3
Kuroda, M.4
Harding, H.5
Ron, D.6
-
132
-
-
0037160091
-
Topology of superoxide production from different sites in the mitochondrial electron transport chain
-
St-Pierre J, Buckingham JA, Roebuck SJ, and Brand MD. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 277: 44784-44790, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 44784-44790
-
-
St-Pierre, J.1
Buckingham, J.A.2
Roebuck, S.J.3
Brand, M.D.4
-
133
-
-
0036710399
-
Importance of individuality in oxidative stress and aging
-
Stadtman ER. Importance of individuality in oxidative stress and aging. Free Radic Biol Med 33: 597-604, 2002.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 597-604
-
-
Stadtman, E.R.1
-
134
-
-
30044441047
-
CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P
-
Stirling J, and O'Hare P. CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. Mol Biol Cell 17: 413-426, 2006.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 413-426
-
-
Stirling, J.1
O'Hare, P.2
-
135
-
-
0036732030
-
Cholesterol in health and disease
-
Tabas I. Cholesterol in health and disease. J Clin Invest 110: 583-590, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 583-590
-
-
Tabas, I.1
-
136
-
-
0036790413
-
Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications
-
Tabas I. Consequences of cellular cholesterol accumulation: basic concepts and physiological implications. J Clin Invest 110: 905-911, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 905-911
-
-
Tabas, I.1
-
137
-
-
33744918550
-
Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis
-
Tan Y, Dourdin N, Wu C, De Veyra T, Elce JS, and Greer PA. Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis. J Biol Chem 281: 16016-16024, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 16016-16024
-
-
Tan, Y.1
Dourdin, N.2
Wu, C.3
De Veyra, T.4
Elce, J.S.5
Greer, P.A.6
-
138
-
-
0033025006
-
Metabolism and degradation products of recombinant human insulin-like growth factor-I in lysosomes of rat kidney
-
Tanaka Y, Tamoto H, Tozuka Z, Sato A, and Kimura T. Metabolism and degradation products of recombinant human insulin-like growth factor-I in lysosomes of rat kidney. Xenobiotica 29: 281-295, 1999.
-
(1999)
Xenobiotica
, vol.29
, pp. 281-295
-
-
Tanaka, Y.1
Tamoto, H.2
Tozuka, Z.3
Sato, A.4
Kimura, T.5
-
139
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon W, Welihinda AA, and Kaufman RJ. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 12: 1812-1824, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
140
-
-
0036193169
-
Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer
-
Tobiume K, Saitoh M, and Ichijo H. Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. J Cell Physiol 191: 95-104, 2002.
-
(2002)
J Cell Physiol
, vol.191
, pp. 95-104
-
-
Tobiume, K.1
Saitoh, M.2
Ichijo, H.3
-
141
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, and Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101: 249-258, 2000.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
Patil, C.K.2
Wodicka, L.3
Lockhart, D.J.4
Weissman, J.S.5
Walter, P.6
-
142
-
-
0842266604
-
Oxidative protein folding in eukaryotes: Mechanisms and consequences
-
Tu BP, and Weissman JS. Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol 164: 341-346, 2004.
-
(2004)
J Cell Biol
, vol.164
, pp. 341-346
-
-
Tu, B.P.1
Weissman, J.S.2
-
143
-
-
33745315287
-
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
-
Uehara T, Nakamura T, Yao D, Shi ZQ, Gu Z, Ma Y, Masliah E, Nomura Y, and Lipton SA. S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature 441: 513-517, 2006.
-
(2006)
Nature
, vol.441
, pp. 513-517
-
-
Uehara, T.1
Nakamura, T.2
Yao, D.3
Shi, Z.Q.4
Gu, Z.5
Ma, Y.6
Masliah, E.7
Nomura, Y.8
Lipton, S.A.9
-
144
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, and Ron D. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287: 664-666, 2000.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
145
-
-
0041761700
-
Oxidation of ER resident proteins upon oxidative stress: Effects of altering cellular redox/antioxidant status and implications for protein maturation
-
van der Vlies D, Makkinje M, Jansens A, Braakman I, Verkleij AJ, Wirtz KW, and Post JA. Oxidation of ER resident proteins upon oxidative stress: effects of altering cellular redox/antioxidant status and implications for protein maturation. Antioxid Redox Signal 5: 381-387, 2003.
-
(2003)
Antioxid Redox Signal
, vol.5
, pp. 381-387
-
-
van der Vlies, D.1
Makkinje, M.2
Jansens, A.3
Braakman, I.4
Verkleij, A.J.5
Wirtz, K.W.6
Post, J.A.7
-
146
-
-
0034665152
-
Nitric oxide-dependent modification of the sarcoplasmic reticulum Ca-ATPase: Localization of cysteine target sites
-
Viner RI, Williams TD, and Schoneich C. Nitric oxide-dependent modification of the sarcoplasmic reticulum Ca-ATPase: localization of cysteine target sites. Free Radic Biol Med 29, 489-496, 2000.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 489-496
-
-
Viner, R.I.1
Williams, T.D.2
Schoneich, C.3
-
147
-
-
33745807575
-
Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain: Inhibition of nuclear translocation and transacting function
-
Wang W, and Chan JY. Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain: inhibition of nuclear translocation and transacting function. J Biol Chem 281: 19676-19687, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 19676-19687
-
-
Wang, W.1
Chan, J.Y.2
-
148
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, and Ron D. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. Embo J 17: 5708-5717, 1998.
-
(1998)
Embo J
, vol.17
, pp. 5708-5717
-
-
Wang, X.Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
149
-
-
0035014266
-
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
-
Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, and Austin RC. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 107: 1263-1273, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 1263-1273
-
-
Werstuck, G.H.1
Lentz, S.R.2
Dayal, S.3
Hossain, G.S.4
Sood, S.K.5
Shi, Y.Y.6
Zhou, J.7
Maeda, N.8
Krisans, S.K.9
Malinow, M.R.10
Austin, R.C.11
-
150
-
-
33645156429
-
From acute ER stress to physiological roles of the unfolded protein response
-
Wu J, and Kaufman RJ. From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 13: 374-384, 2006.
-
(2006)
Cell Death Differ
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
151
-
-
0032498185
-
Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation
-
Xu L, Eu JP, Meissner G, and Stamler JS. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science 279, 234-237, 1998.
-
(1998)
Science
, vol.279
, pp. 234-237
-
-
Xu, L.1
Eu, J.P.2
Meissner, G.3
Stamler, J.S.4
-
152
-
-
26644450729
-
Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha
-
Xue X, Piao JH, Nakajima A, Sakon-Komazawa S, Kojima Y, Mori K, Yagita H, Okumura K, Harding H, and Nakano H. Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha. J Biol Chem 280: 33917-33925, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 33917-33925
-
-
Xue, X.1
Piao, J.H.2
Nakajima, A.3
Sakon-Komazawa, S.4
Kojima, Y.5
Mori, K.6
Yagita, H.7
Okumura, K.8
Harding, H.9
Nakano, H.10
-
153
-
-
8544283103
-
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
-
Yamaguchi H, and Wang HG. CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. J Biol Chem 279: 45495-45502, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 45495-45502
-
-
Yamaguchi, H.1
Wang, H.G.2
-
154
-
-
33744800561
-
Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK
-
Yang Q, Kim YS, Lin Y, Lewis J, Neckers L, and Liu ZG. Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK. EMBO Rep 7: 622-627, 2006.
-
(2006)
EMBO Rep
, vol.7
, pp. 622-627
-
-
Yang, Q.1
Kim, Y.S.2
Lin, Y.3
Lewis, J.4
Neckers, L.5
Liu, Z.G.6
-
155
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
Ye J, Rawson RB, Komuro R, Chen X, Dave UP, Prywes R, Brown MS, and Goldstein JL. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 6: 1355-1364, 2000.
-
(2000)
Mol Cell
, vol.6
, pp. 1355-1364
-
-
Ye, J.1
Rawson, R.B.2
Komuro, R.3
Chen, X.4
Dave, U.P.5
Prywes, R.6
Brown, M.S.7
Goldstein, J.L.8
-
156
-
-
0035957929
-
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
-
Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, and Tohyama M. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 276: 13935-13940, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 13935-13940
-
-
Yoneda, T.1
Imaizumi, K.2
Oono, K.3
Yui, D.4
Gomi, F.5
Katayama, T.6
Tohyama, M.7
-
157
-
-
0032509216
-
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors
-
Yoshida H, Haze K, Yanagi H, Yura T, and Mori K. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J Biol Chem 273: 33741-33749, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 33741-33749
-
-
Yoshida, H.1
Haze, K.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
158
-
-
0037320265
-
time-dependent phase shift in the mammalian unfolded protein response
-
Yoshida H, Matsui T, Hosokawa N, Kaufman RJ, Nagata K, and Mori KA. time-dependent phase shift in the mammalian unfolded protein response. Dev Cell 4: 265-271, 2003.
-
(2003)
Dev Cell
, vol.4
, pp. 265-271
-
-
Yoshida, H.1
Matsui, T.2
Hosokawa, N.3
Kaufman, R.J.4
Nagata, K.5
Mori, K.A.6
-
159
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H, Matsui T, Yamamoto A, Okada T, and Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107: 881-891, 2001.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
160
-
-
0033815971
-
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
-
Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, and Mori K. ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response. Mol Cell Biol 20: 6755-6767, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6755-6767
-
-
Yoshida, H.1
Okada, T.2
Haze, K.3
Yanagi, H.4
Yura, T.5
Negishi, M.6
Mori, K.7
-
161
-
-
0035141230
-
Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response
-
Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, and Mori K. Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response. Mol Cell Biol 21: 1239-1248, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1239-1248
-
-
Yoshida, H.1
Okada, T.2
Haze, K.3
Yanagi, H.4
Yura, T.5
Negishi, M.6
Mori, K.7
-
162
-
-
0035929641
-
Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response
-
Zhang C, Cai Y, Adachi MT, Oshiro S, Aso T, Kaufman RJ, and Kitajima S. Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response. J Biol Chem 276: 35867-35874, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 35867-35874
-
-
Zhang, C.1
Cai, Y.2
Adachi, M.T.3
Oshiro, S.4
Aso, T.5
Kaufman, R.J.6
Kitajima, S.7
-
163
-
-
0035824403
-
Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine
-
Zhang C, Kawauchi J, Adachi MT, Hashimoto Y, Oshiro S, Aso T, and Kitajima S. Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine. Biochem Biophys Res Commun 289: 718-724, 2001.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 718-724
-
-
Zhang, C.1
Kawauchi, J.2
Adachi, M.T.3
Hashimoto, Y.4
Oshiro, S.5
Aso, T.6
Kitajima, S.7
-
164
-
-
32044453080
-
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
-
Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, and Kaufman RJ. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell 124: 587-599, 2006.
-
(2006)
Cell
, vol.124
, pp. 587-599
-
-
Zhang, K.1
Shen, X.2
Wu, J.3
Sakaki, K.4
Saunders, T.5
Rutkowski, D.T.6
Back, S.H.7
Kaufman, R.J.8
-
165
-
-
14944371187
-
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis
-
Zhang K, Wong HN, Song B, Miller CN, Scheuner D, and Kaufman RJ. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest 115: 268-281, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 268-281
-
-
Zhang, K.1
Wong, H.N.2
Song, B.3
Miller, C.N.4
Scheuner, D.5
Kaufman, R.J.6
-
166
-
-
25144520251
-
Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP
-
Zhao L, Longo-Guess C, Harris BS, Lee JWm and Ackerman SL. Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nat Genet 37: 974-979, 2005.
-
(2005)
Nat Genet
, vol.37
, pp. 974-979
-
-
Zhao, L.1
Longo-Guess, C.2
Harris, B.S.3
Lee, J.W.4
Ackerman, S.L.5
-
167
-
-
33749233991
-
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
-
Zhou J, Liu CY, Back SH, Clark RL, Peisach D, Xu Z, and Kaufman RJ. The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc Natl Acad Sci U S A 103: 14343-14348, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14343-14348
-
-
Zhou, J.1
Liu, C.Y.2
Back, S.H.3
Clark, R.L.4
Peisach, D.5
Xu, Z.6
Kaufman, R.J.7
-
168
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, and Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12: 982-995, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
Batchvarova, N.4
Lightfoot, R.T.5
Remotti, H.6
Stevens, J.L.7
Ron, D.8
-
169
-
-
0037810844
-
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
-
Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan JM, and Thompson CB. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol 162: 59-69, 2003.
-
(2003)
J Cell Biol
, vol.162
, pp. 59-69
-
-
Zong, W.X.1
Li, C.2
Hatzivassiliou, G.3
Lindsten, T.4
Yu, Q.C.5
Yuan, J.M.6
Thompson, C.B.7
-
170
-
-
0035876483
-
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR, and Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15: 1481-1486, 2001.
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR, and Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15: 1481-1486, 2001.
-
-
-
|