4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells

Journal of Biological Chemistry

Volumn 286, Issue 52, 2011, Pages 45083-45092

  Suaud, Laurence ^a   Miller, Katelyn ^a   Panichelli, Ashley E ^a   Randell, Rachel L ^a   Marando, Catherine M ^a   Rubenstein, Ronald C ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTIC FIBROSIS; EPITHELIAL CELLS; HEAT SHOCK PROTEIN; HSP70 EXPRESSION; LUCIFERASE REPORTER ASSAYS; MRNA TRANSCRIPTION; NUCLEAR PROTEINS; OVER-EXPRESSION; PROMOTER ACTIVITIES; PROTEIN EXPRESSIONS; RNA POLYMERASE II; SIGNAL TRANSDUCERS; SMALL INTERFERING RNA; STRESS-INDUCED;

CELLS; CHEMICAL ACTIVATION; RNA; SODIUM; TRANSCRIPTION;

PROTEINS;

4 PHENYLBUTYRIC ACID; BINDING PROTEIN; ELONGATOR PROTEIN 2; HEAT SHOCK PROTEIN 70; MESSENGER RNA; NUCLEAR PROTEIN; REGULATOR PROTEIN; RNA POLYMERASE II; SMALL INTERFERING RNA; STAT3 INTERACTING PROTEIN 1; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BRONCHIOLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DNA RESPONSIVE ELEMENT; ENZYME REGULATION; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYSTIC FIBROSIS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHENYLBUTYRATES; PROMOTER REGIONS, GENETIC; RESPIRATORY MUCOSA; RNA POLYMERASE II; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR;

EID: 84455173094     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.293282     Document Type: Article

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