Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC complexes

European Journal of Pharmacology

Volumn 754, Issue , 2015, Pages 162-172

  Vineetha, Vadavanath Prabhakaran ^a   Soumya, Rema Sreenivasan ^a   Raghu, Kozhiparambil Gopalan ^a  

^a REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

Arsenic trioxide; Electron transport chain; H9c2 cells; Mitochondrial swelling; Oxygen consumption; Phloretin

Indexed keywords

ACONITATE HYDRATASE; ADENOSINE TRIPHOSPHATE; ARSENIC TRIOXIDE; CASPASE 3; PHLORETIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; XANTHINE OXIDASE; ANTIOXIDANT; CALCIUM; MULTIENZYME COMPLEX; ORGANOARSENIC DERIVATIVE; OXIDE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CARDIOMYOBLAST; CARDIOTOXICITY; CELL MEMBRANE PERMEABILITY; CELL PROTECTION; CELL STRESS; CELL VIABILITY; CELLULAR STRESS RESPONSE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG PROTEIN BINDING; DRUG TARGETING; EMBRYO; ENZYME INHIBITION; HEART MUSCLE CELL; HEART PROTECTION; MEMBRANE DAMAGE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; DRUG EFFECTS; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MYOBLAST; PATHOLOGY; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ARSENICALS; CALCIUM; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MYOBLASTS; MYOCYTES, CARDIAC; OXIDATIVE STRESS; OXIDES; OXYGEN CONSUMPTION; PHLORETIN; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84924599479     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.02.036     Document Type: Article

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