The unfolded protein response transducer IRE1Î ± prevents ER stress-induced hepatic steatosis

EMBO Journal

Volumn 30, Issue 7, 2011, Pages 1357-1375

  Zhang, Kezhong ^a,b   Wang, Shiyu ^a   Malhotra, Jyoti ^a   Hassler, Justin R ^a   Back, Sung Hoon ^a   Wang, Guohui ^b   Chang, Lin ^a   Xu, Wenbo ^b   Miao, Hongzhi ^a   Leonardi, Roberta ^c   Chen, Y Eugene ^a   Jackowski, Suzanne ^c   Kaufman, Randal J ^a,d  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

ER stress; hepatic steatosis; unfolded protein response

Indexed keywords

APOLIPOPROTEIN; BLOOD CLOTTING FACTOR 8; BORTEZOMIB; CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN DELTA; CRE RECOMBINASE; INOSITOL REQUIRING ENZYME 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RIBONUCLEASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; GENE DELETION; GENE INDUCTION; GOLGI COMPLEX; HOMEOSTASIS; HYPOLIPEMIA; LIPID LIVER LEVEL; LIPID STORAGE; LIPOPROTEIN SECRETION; LIVER CELL; LIVER RESECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; FATTY LIVER; GENE EXPRESSION PROFILING; MICE; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; UNFOLDED PROTEIN RESPONSE;

MUS;

EID: 79953794116     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.52     Document Type: Article

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