In the Huh7 hepatoma cells diclofenac and indomethacin activate differently the unfolded protein response and induce ER stress apoptosis

Open Biochemistry Journal

Volumn 5, Issue , 2011, Pages 45-51

  Franceschelli, Silvia ^a   Moltedo, Ornella ^a   Amodio, Giuseppina ^a   Tajana, Gianfranco ^a   Remondelli, Paolo ^a  

^a UNIVERSITY OF SALERNO   (Italy)

Author keywords

Apoptosis; ATF6 ; Diclofenac; ER stress; Indomethacin; IRE1; NSAID; PERK; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; DICLOFENAC; ENDONUCLEASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PANCREATIC ER KINASE LIKE; PHOSPHOTRANSFERASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN IRE1; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL LINE; CELL STRAIN HUH7; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE;

EID: 80053441126     PISSN: None     EISSN: 1874091X     Source Type: Journal    
DOI: 10.2174/1874091X01105010045     Document Type: Article

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