Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin A as model compounds: An omics-guided approach

OMICS A Journal of Integrative Biology

Volumn 17, Issue 2, 2013, Pages 71-83

  Van Summeren, Anke ^a   Renes, Johan ^a   Lizarraga, Daneida ^a   Bouwman, Freek G ^a   Noben, Jean Paul ^b   Van Delft, Joost H M ^a   Kleinjans, Jos C S ^a   Mariman, Edwin C M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b HASSELT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; CARBOXYLESTERASE; CYCLOSPORIN A; MESSENGER RNA; PARACETAMOL; SULFOTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN HEPG2; CELL TRANSPORT; CHOLESTASIS; CONTROLLED STUDY; DIFFERENTIAL IN GEL ELECTROPHORESIS; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG SCREENING; ENDOPLASMIC RETICULUM STRESS; GEL ELECTROPHORESIS; LIVER CELL; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; WESTERN BLOTTING;

ACETAMINOPHEN; AMIODARONE; ANIMALS; CELL LINE; CLUSTER ANALYSIS; CYCLOSPORINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOMICS; HEP G2 CELLS; HEPATOCYTES; HUMANS; MALE; MICE; PRIMARY CELL CULTURE; PROTEOME; PROTEOMICS;

EID: 84873381429     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2012.0079     Document Type: Article

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