-
2
-
-
79952758037
-
Inter-Relationship between Cardiac Hypertrophy, Heart Failure and Chronic Kidney Disease - Endoplasmic Reticulum Stress as a Mediator of Pathogenesis
-
Dickhout JG, Carlisle RE, Austin RC (2011) Inter-Relationship between Cardiac Hypertrophy, Heart Failure and Chronic Kidney Disease - Endoplasmic Reticulum Stress as a Mediator of Pathogenesis. Circ Res 108: 629-642.
-
(2011)
Circ Res
, vol.108
, pp. 629-642
-
-
Dickhout, J.G.1
Carlisle, R.E.2
Austin, R.C.3
-
3
-
-
68949209952
-
Endoplasmic reticulum stress and renal disease
-
Dickhout JG, Krepinsky JC (2009) Endoplasmic reticulum stress and renal disease. Antioxid Redox Signal 11: 2341-2352.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2341-2352
-
-
Dickhout, J.G.1
Krepinsky, J.C.2
-
4
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter P, Ron D (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334: 1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
5
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
DOI 10.1101/gad.1250704
-
Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, et al. (2004) CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 18: 3066-3077. (Pubitemid 39658175)
-
(2004)
Genes and Development
, vol.18
, Issue.24
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
6
-
-
65449117250
-
The protective effect of a newly developed molecular chaperone-inducer against mouse ischemic acute kidney injury
-
Prachasilchai W, Sonoda H, Yokota-Ikeda N, Ito K, Kudo T, et al. (2009) The protective effect of a newly developed molecular chaperone-inducer against mouse ischemic acute kidney injury. J Pharmacol Sci 109: 311-314.
-
(2009)
J Pharmacol Sci
, vol.109
, pp. 311-314
-
-
Prachasilchai, W.1
Sonoda, H.2
Yokota-Ikeda, N.3
Ito, K.4
Kudo, T.5
-
7
-
-
49749143335
-
A protective role of unfolded protein response in mouse ischemic acute kidney injury
-
Prachasilchai W, Sonoda H, Yokota-Ikeda N, Oshikawa S, Aikawa C, et al. (2008) A protective role of unfolded protein response in mouse ischemic acute kidney injury. Eur J Pharmacol 592: 138-145.
-
(2008)
Eur J Pharmacol
, vol.592
, pp. 138-145
-
-
Prachasilchai, W.1
Sonoda, H.2
Yokota-Ikeda, N.3
Oshikawa, S.4
Aikawa, C.5
-
8
-
-
34547889887
-
Calpain inhibition but not reticulum endoplasmic stress preconditioning protects rat kidneys from p-aminophenol toxicity
-
DOI 10.1093/toxsci/kfm105
-
Peyrou M, Hanna PE and Cribb AE (2007) Calpain inhibition but not reticulum endoplasmic stress preconditioning protects rat kidneys from p-aminophenol toxicity. Toxicol Sci 99: 338-345. (Pubitemid 47250390)
-
(2007)
Toxicological Sciences
, vol.99
, Issue.1
, pp. 338-345
-
-
Peyrou, M.1
Hanna, P.E.2
Cribb, A.E.3
-
9
-
-
34247144663
-
Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines
-
DOI 10.1016/j.tiv.2007.03.001, PII S0887233307000653
-
Peyrou M, Cribb AE (2007) Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines. Toxicol In Vitro 21: 878-886. (Pubitemid 46603248)
-
(2007)
Toxicology in Vitro
, vol.21
, Issue.5
, pp. 878-886
-
-
Peyrou, M.1
Cribb, A.E.2
-
10
-
-
77951614322
-
The role of endoplasmic reticulum stress-related unfolded protein response in the radiocontrast medium-induced renal tubular cell injury
-
Wu CT, Sheu ML, Tsai KS, Weng TI, Chiang CK, et al. (2010) The role of endoplasmic reticulum stress-related unfolded protein response in the radiocontrast medium-induced renal tubular cell injury. Toxicol Sci 114: 295-301.
-
(2010)
Toxicol Sci
, vol.114
, pp. 295-301
-
-
Wu, C.T.1
Sheu, M.L.2
Tsai, K.S.3
Weng, T.I.4
Chiang, C.K.5
-
11
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, et al. (1998) CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12: 982-995. (Pubitemid 28204605)
-
(1998)
Genes and Development
, vol.12
, Issue.7
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
Batchvarova, N.4
Lightfoot, R.T.5
Remotti, H.6
Stevens, J.L.7
Ron, D.8
-
12
-
-
84863959263
-
ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death
-
Lhotak S, Sood S, Brimble E, Carlisle RE, Colgan SM, et al. (2012) ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death. Am J Physiol Renal Physiol 303: F266-278.
-
(2012)
Am J Physiol Renal Physiol
, vol.303
-
-
Lhotak, S.1
Sood, S.2
Brimble, E.3
Carlisle, R.E.4
Colgan, S.M.5
-
13
-
-
0036238921
-
N-linked glycosylation is critical for the plasma membrane localization of nephrin
-
DOI 10.1097/01.ASN.0000013297.11876.5B
-
Yan K, Khoshnoodi J, Ruotsalainen V, Tryggvason K (2002) N-linked glycosylation is critical for the plasma membrane localization of nephrin. J Am Soc Nephrol 13: 1385-1389. (Pubitemid 34441421)
-
(2002)
Journal of the American Society of Nephrology
, vol.13
, Issue.5
, pp. 1385-1389
-
-
Yan, K.1
Khoshnoodi, J.2
Ruotsalainen, V.3
Tryggvason, K.4
-
14
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
DOI 10.1038/47513
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, et al. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103. (Pubitemid 30038529)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
15
-
-
79952185509
-
Increased susceptibility to acute kidney injury due to endoplasmic reticulum stress in mice lacking tumor necrosis factor-alpha and its receptor 1
-
Huang L, Zhang R, Wu J, Chen J, Grosjean F, et al. (2011) Increased susceptibility to acute kidney injury due to endoplasmic reticulum stress in mice lacking tumor necrosis factor-alpha and its receptor 1. Kidney Int 79: 613-623.
-
(2011)
Kidney Int
, vol.79
, pp. 613-623
-
-
Huang, L.1
Zhang, R.2
Wu, J.3
Chen, J.4
Grosjean, F.5
-
16
-
-
79960848652
-
Ammonia control in children with urea cycle disorders (UCDs); phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate
-
Lichter-Konecki U, Diaz GA, Merritt JL 2nd, Feigenbaum A, Jomphe C, et al. (2011) Ammonia control in children with urea cycle disorders (UCDs); phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate. Mol Genet Metab 103: 323-329.
-
(2011)
Mol Genet Metab
, vol.103
, pp. 323-329
-
-
Lichter-Konecki, U.1
Diaz, G.A.2
Merritt II, J.L.3
Feigenbaum, A.4
Jomphe, C.5
-
17
-
-
83155172382
-
Radioprotection by the histone deacetylase inhibitor phenylbutyrate
-
Miller AC, Cohen S, Stewart M, Rivas R, Lison P (2011) Radioprotection by the histone deacetylase inhibitor phenylbutyrate. Radiat Environ Biophys 50: 585-596.
-
(2011)
Radiat Environ Biophys
, vol.50
, pp. 585-596
-
-
Miller, A.C.1
Cohen, S.2
Stewart, M.3
Rivas, R.4
Lison, P.5
-
18
-
-
68949214283
-
The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response
-
Basseri S, Lhotak S, Sharma AM, Austin RC (2009) The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response. J Lipid Res 50: 2486-2501.
-
(2009)
J Lipid Res
, vol.50
, pp. 2486-2501
-
-
Basseri, S.1
Lhotak, S.2
Sharma, A.M.3
Austin, R.C.4
-
19
-
-
79952410092
-
Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans
-
Xiao C, Giacca A, Lewis GF (2011) Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans. Diabetes 60: 918-924.
-
(2011)
Diabetes
, vol.60
, pp. 918-924
-
-
Xiao, C.1
Giacca, A.2
Lewis, G.F.3
-
20
-
-
34248376062
-
Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis
-
DOI 10.1167/iovs.06-0943
-
Yam GH, Gaplovska-Kysela K, Zuber C, Roth J, Yam GH-F, et al. (2007) Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis. Investigative Ophthalmology & Visual Science 48: 1683-1690. (Pubitemid 351261354)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.4
, pp. 1683-1690
-
-
Yam, G.H.-F.1
Gaplovska-Kysela, K.2
Zuber, C.3
Roth, J.4
-
21
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, et al. (2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313: 1137-1140. (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
23
-
-
0028870221
-
Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: A clinical trial
-
Collins AF, Pearson HA, Giardina P, McDonagh KT, Brusilow SW, et al. (1995) Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial. Blood 85: 43-49.
-
(1995)
Blood
, vol.85
, pp. 43-49
-
-
Collins, A.F.1
Pearson, H.A.2
Giardina, P.3
McDonagh, K.T.4
Brusilow, S.W.5
-
24
-
-
84855708250
-
Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress
-
Mimori S, Okuma Y, Kaneko M, Kawada K, Hosoi T, et al. (2012) Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress. Biol Pharm Bull 35: 84-90.
-
(2012)
Biol Pharm Bull
, vol.35
, pp. 84-90
-
-
Mimori, S.1
Okuma, Y.2
Kaneko, M.3
Kawada, K.4
Hosoi, T.5
-
25
-
-
0037057516
-
Phenylbutyrate inhibits the invasive properties of prostate and breast cancer cell lines in the sea urchin embryo basement membrane invasion assay
-
Dyer ES, Paulsen MT, Markwart SM, Goh M, Livant DL, et al. (2002) Phenylbutyrate inhibits the invasive properties of prostate and breast cancer cell lines in the sea urchin embryo basement membrane invasion assay. Int J Cancer 101: 496-499.
-
(2002)
Int J Cancer
, vol.101
, pp. 496-499
-
-
Dyer, E.S.1
Paulsen, M.T.2
Markwart, S.M.3
Goh, M.4
Livant, D.L.5
-
26
-
-
0029962932
-
Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate
-
Carducci MA, Nelson JB, Chan-Tack KM, Ayyagari SR, Sweatt WH, et al. (1996) Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate. Clin Cancer Res 2: 379-387. (Pubitemid 26075641)
-
(1996)
Clinical Cancer Research
, vol.2
, Issue.2
, pp. 379-387
-
-
Carducci, M.A.1
Nelson, J.B.2
Chan-Tack, K.M.3
Ayyagari, S.R.4
Sweatt, W.H.5
Campbell, P.A.6
Nelson, W.G.7
Simons, J.W.8
-
27
-
-
17844410310
-
Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: A dose escalation and pharmacologic study
-
DOI 10.1215/S1152851704000183
-
Phuphanich S, Baker SD, Grossman SA, Carson KA, Gilbert MR, et al. (2005) Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: a dose escalation and pharmacologic study. Neuro Oncol 7: 177-182. (Pubitemid 40590517)
-
(2005)
Neuro-Oncology
, vol.7
, Issue.2
, pp. 177-182
-
-
Phuphanich, S.1
Baker, S.D.2
Grossman, S.A.3
Carson, K.A.4
Gilbert, M.R.5
Fisher, J.D.6
Carducci, M.A.7
-
28
-
-
0028010818
-
HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney
-
Ryan MJ, Johnson G, Kirk J, Fuerstenberg SM, Zager RA, et al. (1994) HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int 45: 48-57. (Pubitemid 24045991)
-
(1994)
Kidney International
, vol.45
, Issue.1
, pp. 48-57
-
-
Ryan, M.J.1
Johnson, G.2
Kirk, J.3
Fuerstenberg, S.M.4
Zager, R.A.5
Torok-Storb, B.6
-
29
-
-
0041989674
-
TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia
-
DOI 10.1074/jbc.M212897200
-
Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, et al. (2003) TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. J Biol Chem 278: 30317-30327. (Pubitemid 36962426)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.32
, pp. 30317-30327
-
-
Hossain, G.S.1
Van Thienen, J.V.2
Werstuck, G.H.3
Zhou, J.4
Sood, S.K.5
Dickhout, J.G.6
De Koning, A.B.L.7
Tang, D.8
Wu, D.9
Falk, E.10
Poddar, R.11
Jacobsen, D.W.12
Zhang, K.13
Kaufman, R.J.14
Austin, R.C.15
-
30
-
-
79551635705
-
Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions
-
Dickhout JG, Lhotak S, Hilditch BA, Basseri S, Colgan SM, et al. (2011) Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions. FASEB J 25: 576-589.
-
(2011)
FASEB J
, vol.25
, pp. 576-589
-
-
Dickhout, J.G.1
Lhotak, S.2
Hilditch, B.A.3
Basseri, S.4
Colgan, S.M.5
-
31
-
-
84863293129
-
Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine gamma-Lyase: CROSS-TALK BETWEEN INTEGRATED STRESS RESPONSE AND THIOL METABOLISM
-
Dickhout JG, Carlisle RE, Jerome DE, Mohammed-Ali Z, Jiang H, et al. (2012) Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine gamma-Lyase: CROSS-TALK BETWEEN INTEGRATED STRESS RESPONSE AND THIOL METABOLISM. J Biol Chem 287: 7603-7614.
-
(2012)
J Biol Chem
, vol.287
, pp. 7603-7614
-
-
Dickhout, J.G.1
Carlisle, R.E.2
Jerome, D.E.3
Mohammed-Ali, Z.4
Jiang, H.5
-
32
-
-
84864742240
-
TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium
-
Carlisle RE, Heffernan A, Brimble E, Liu L, Jerome D, et al. (2012) TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium. Am J Physiol Renal Physiol 303: F467-481.
-
(2012)
Am J Physiol Renal Physiol
, vol.303
-
-
Carlisle, R.E.1
Heffernan, A.2
Brimble, E.3
Liu, L.4
Jerome, D.5
-
33
-
-
79551474362
-
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation
-
Wang FM, Chen YJ, Ouyang HJ (2011) Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation. Biochem J 433: 245-252.
-
(2011)
Biochem J
, vol.433
, pp. 245-252
-
-
Wang, F.M.1
Chen, Y.J.2
Ouyang, H.J.3
-
34
-
-
84863084759
-
Inhibition of casein kinase 2 modulates XBP1-GRP78 arm of unfolded protein responses in cultured glial cells
-
Hosoi T, Korematsu K, Horie N, Suezawa T, Okuma Y, et al. (2012) Inhibition of casein kinase 2 modulates XBP1-GRP78 arm of unfolded protein responses in cultured glial cells. PLoS One 7: e40144.
-
(2012)
PLoS One
, vol.7
-
-
Hosoi, T.1
Korematsu, K.2
Horie, N.3
Suezawa, T.4
Okuma, Y.5
-
35
-
-
84885188725
-
4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor
-
Mimori S, Ohtaka H, Koshikawa Y, Kawada K, Kaneko M, et al. (2013) 4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor. Bioorg Med Chem Lett 23: 6015-6018.
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 6015-6018
-
-
Mimori, S.1
Ohtaka, H.2
Koshikawa, Y.3
Kawada, K.4
Kaneko, M.5
-
36
-
-
38149136598
-
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
-
Ota T, Gayet C, Ginsberg HN (2008) Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents. J Clin Invest 118: 316-332.
-
(2008)
J Clin Invest
, vol.118
, pp. 316-332
-
-
Ota, T.1
Gayet, C.2
Ginsberg, H.N.3
-
37
-
-
34948859111
-
Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation
-
DOI 10.1074/jbc.M702672200
-
de Almeida SF, Picarote G, Fleming JV, Carmo-Fonseca M, Azevedo JE, et al. (2007) Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation. J Biol Chem 282: 27905-27912. (Pubitemid 47529490)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.38
, pp. 27905-27912
-
-
De Almeida, S.F.1
Picarote, G.2
Fleming, J.V.3
Carmo-Fonseca, M.4
Azevedo, J.E.5
De Sousa, M.6
-
38
-
-
0037442389
-
Deletion of exon 4 from human surfactant protein C results in aggresome formation and generation of a dominant negative
-
DOI 10.1242/jcs.00267
-
Wang WJ, Mulugeta S, Russo SJ, Beers MF (2003) Deletion of exon 4 from human surfactant protein C results in aggresome formation and generation of a dominant negative. J Cell Sci 116: 683-692. (Pubitemid 36231307)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.4
, pp. 683-692
-
-
Wang, W.-J.1
Mulugeta, S.2
Russo, S.J.3
Beers, M.F.4
-
39
-
-
73349141743
-
Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling
-
Woo CW, Cui D, Arellano J, Dorweiler B, Harding H, et al. (2009) Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling. Nat Cell Biol 11: 1473-1480.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1473-1480
-
-
Woo, C.W.1
Cui, D.2
Arellano, J.3
Dorweiler, B.4
Harding, H.5
|