A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells

Toxicology and Applied Pharmacology

Volumn 258, Issue 2, 2012, Pages 275-287

  Sarró, Eduard ^a,b   Jacobs Cachá, Conxita ^b   Itarte, Emilio ^a   Meseguer, Anna ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

Array; Cyclosporine A; Cytotoxicity; Endoplasmic reticulum (ER) stress; Pharmaceuticals

Indexed keywords

ANTIOXIDANT; CASEIN KINASE II; CYCLOSPORIN A; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE; MATRIX METALLOPROTEINASE; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM METABOLISM; CELL STRESS; CELL STRUCTURE; CELL VIABILITY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MOUSE; NONHUMAN; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CYCLOSPORINE; ENDOPLASMIC RETICULUM STRESS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TUBULES, PROXIMAL; MATRIX METALLOPROTEINASES; MICE; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES;

EID: 84855821174     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.11.007     Document Type: Article

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