Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy

Free Radical Biology and Medicine

Volumn 52, Issue 2, 2012, Pages 497-506

  Mukhopadhyay, Partha ^a   Horváth, Béla ^a,d   Zsengellér, Zsuzsanna ^b   Zielonka, Jacek ^c   Tanchian, Galin ^a   Holovac, Eileen ^a   Kechrid, Malek ^a   Patel, Vivek ^a   Stillman, Isaac E ^b   Parikh, Samir M ^b   Joseph, Joy ^c   Kalyanaraman, Balaraman ^c   Pacher, Pál ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c FREE RADICAL RESEARCH CENTER   (United States)

^d SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Cisplatin; Free radicals; Mitochondria; Mitochondrial antioxidants; Nephropathy; Oxidative stress

Indexed keywords

ANTIOXIDANT; CISPLATIN; MITO CP; MITO Q; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; DETERIORATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HUMAN; HUMAN CELL; INFLAMMATION; KIDNEY DISEASE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SINGLE DRUG DOSE;

ACUTE KIDNEY INJURY; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; CYCLIC N-OXIDES; CYTOPROTECTION; ELECTRON TRANSPORT COMPLEX IV; HUMANS; INFLAMMATION; KIDNEY TUBULES; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NADH DEHYDROGENASE; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; UBIQUINONE;

VASCONCELLEA CANDICANS;

EID: 84855448154     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.11.001     Document Type: Article

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