CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

Genes and Development

Volumn 18, Issue 24, 2004, Pages 3066-3077

  Marciniak, Stefan J ^a   Yun, Chi Y ^a   Oyadomari, Seiichi ^a   Novoa, Isabel ^a   Zhang, Yuhong ^a   Jungreis, Rivka ^a   Nagata, Kazuhiro ^b   Harding, Heather P ^a   Ron, David ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Chaperones; Gene expression; Membranes; Protein folding; Protein phosphorylation; Secretion

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; INITIATION FACTOR; ISOPROTEIN; OXIDOREDUCTASE; SERINE DERIVATIVE; TUNICAMYCIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEATH; DEPHOSPHORYLATION; EMBRYO; ENDOPLASMIC RETICULUM; EXPOSURE; MOLECULAR WEIGHT; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; STRESS; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, DIFFERENTIATION; CAENORHABDITIS ELEGANS; CCAAT-ENHANCER-BINDING PROTEINS; CELL CYCLE PROTEINS; CELL DEATH; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; FIBROBLASTS; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; KIDNEY; KIDNEY TUBULAR NECROSIS, ACUTE; MICE; NEOPLASM PROTEINS; PROTEIN BIOSYNTHESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TUNICAMYCIN;

ANIMALIA;

EID: 10644233167     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1250704     Document Type: Article

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