BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury

Toxicology and Applied Pharmacology

Volumn 243, Issue 1, 2010, Pages 96-103

  Nagy, Gábor ^a   Szarka, András ^b   Lotz, Gábor ^a   Dóczi, Judit ^a   Wunderlich, Lívius ^a   Kiss, András ^a   Jemnitz, Katalin ^c   Veres, Zsuzsa ^c   Bánhegyi, Gábor ^a   Schaff, Zsuzsa ^a   Sümegi, Balázs ^d   Mandl, József ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^c CHEMICAL RESEARCH CENTER   (Hungary)

^d UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Acetaminophen; AIF; BGP 15; Endoplasmic reticulum; Liver; Mitochondria; Programmed cell death

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE; GLUTATHIONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; O (2 HYDROXY 3 PIPERIDINOPROPYL)NICOTINIC AMIDOXIME; PARACETAMOL; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; INHIBITION KINETICS; LIVER PROTECTION; LIVER TOXICITY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REDOX STRESS; SIGNAL TRANSDUCTION;

ACETAMINOPHEN; ANIMALS; APOPTOSIS; CASPASES; DRUG-INDUCED LIVER INJURY; ENDOPLASMIC RETICULUM; HEPATOCYTES; LIVER; MALE; MICE; OXIDATION-REDUCTION; OXIMES; PIPERIDINES; TRANSAMINASES;

EID: 75449085494     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.11.017     Document Type: Article

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