UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

Developmental Cell

Volumn 15, Issue 6, 2008, Pages 829-840

  Rutkowski, D Thomas ^a   Wu, Jun ^a   Back, Sung Hoon ^a   Callaghan, Michael U ^a,b   Ferris, Sean P ^a   Iqbal, Jahangir ^c   Clark, Robert ^a   Miao, Hongzhi ^a   Hassler, Justin R ^a   Fornek, Jamie ^d   Katze, Michael G ^d   Hussain, M Mahmood ^c   Song, Benbo ^a   Swathirajan, Jayanth ^a   Wang, Junying ^a   Yau, Grace D Y ^a   Kaufman, Randal J ^a,e  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SUNY DOWNSTATE MEDICAL CENTER   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

CELLBIO; HUMDISEASE

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CCAAT ENHANCER BINDING PROTEIN; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN P58; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELF 2 ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME REPRESSION; FATTY LIVER; GENE REGULATORY NETWORK; HOMEOSTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; REGULATORY MECHANISM; REPRESSOR GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; ENDOPLASMIC RETICULUM; FATTY LIVER; GENE EXPRESSION REGULATION; HOMEOSTASIS; LIPIDS; LIVER; MICE; PHENOTYPE; PROTEIN FOLDING; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION, GENETIC;

MUS;

EID: 57049111040     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2008.10.015     Document Type: Article

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