-
1
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
DOI 10.1126/science.1141448
-
Balch, W. E., Morimoto, R. I., Dillin, A. & Kelly, J. W. Adapting proteostasis for disease intervention. Science 319, 916-919 (2008). (Pubitemid 351263754)
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
2
-
-
84875461582
-
Diversity in the origins of proteostasis networks-A driver for protein function in evolution
-
Powers, E. T. & Balch, W. E. Diversity in the origins of proteostasis networks-a driver for protein function in evolution. Nat. Rev. Mol. Cell Biol. 14, 237-248 (2013).
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 237-248
-
-
Powers, E.T.1
Balch, W.E.2
-
3
-
-
84871734834
-
Signaling the mitochondrial unfolded protein response
-
Pellegrino, M. W., Nargund, A. M. & Haynes, C. M. Signaling the mitochondrial unfolded protein response. Biochim. Biophys. Acta 1833, 410-416 (2013).
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 410-416
-
-
Pellegrino, M.W.1
Nargund, A.M.2
Haynes, C.M.3
-
6
-
-
77949730282
-
Endoplasmic reticulum stress as a progression factor for kidney injury
-
Inagi, R. Endoplasmic reticulum stress as a progression factor for kidney injury. Curr. Opin. Pharmacol. 10, 156-165 (2010).
-
(2010)
Curr. Opin. Pharmacol.
, vol.10
, pp. 156-165
-
-
Inagi, R.1
-
7
-
-
77950364724
-
The influence of the intrauterine environment on human placental development
-
Burton, G. J., Jauniaux, E. & Charnock-Jones, D. S. The influence of the intrauterine environment on human placental development. Int. J. Dev. Biol. 54, 303-312 (2010).
-
(2010)
Int. J. Dev. Biol.
, vol.54
, pp. 303-312
-
-
Burton, G.J.1
Jauniaux, E.2
Charnock-Jones, D.S.3
-
8
-
-
8444250981
-
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
-
DOI 10.1083/jcb.200405153
-
Kimata, Y., Oikawa, D., Shimizu, Y., Ishiwata-Kimata, Y. & Kohno, K. A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. J. Cell Biol. 167, 445-456 (2004). (Pubitemid 39489053)
-
(2004)
Journal of Cell Biology
, vol.167
, Issue.3
, pp. 445-456
-
-
Kimata, Y.1
Oikawa, D.2
Shimizu, Y.3
Ishiwata-Kimata, Y.4
Kohno, K.5
-
9
-
-
77955023666
-
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
-
Pincus, D. et al. BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol. 8, e1000415 (2010).
-
(2010)
PLoS Biol.
, vol.8
-
-
Pincus, D.1
-
10
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
DOI 10.1073/pnas.0509487102
-
Credle, J. J., Finer-Moore, J. S., Papa, F. R., Stroud, R. M. & Walter, P. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc. Natl Acad. Sci. USA 102, 18773-18784 (2005). (Pubitemid 43049523)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.52
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
11
-
-
34347386472
-
Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis
-
DOI 10.1002/jcp.21051
-
Hom, J. R., Gewandter, J. S., Michael, L., Sheu, S. S. & Yoon, Y. Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis. J. Cell Physiol. 212, 498-508 (2007). (Pubitemid 47025640)
-
(2007)
Journal of Cellular Physiology
, vol.212
, Issue.2
, pp. 498-508
-
-
Hom, J.R.1
Gewandter, J.S.2
Michael, L.3
Sheu, S.-S.4
Yoon, Y.5
-
12
-
-
79952758037
-
Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: Endoplasmic reticulum stress as a mediator of pathogenesis
-
Dickhout, J. G., Carlisle, R. E. & Austin, R. C. Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis. Circ. Res. 108, 629-642 (2011).
-
(2011)
Circ. Res.
, vol.108
, pp. 629-642
-
-
Dickhout, J.G.1
Carlisle, R.E.2
Austin, R.C.3
-
13
-
-
79961124071
-
The unfolded protein response and proteostasis in Alzheimer disease: Preferential activation of autophagy by endoplasmic reticulum stress
-
Scheper, W., Nijholt, D. A. & Hoozemans, J. J. The unfolded protein response and proteostasis in Alzheimer disease: preferential activation of autophagy by endoplasmic reticulum stress. Autophagy 7, 910-911 (2011).
-
(2011)
Autophagy
, vol.7
, pp. 910-911
-
-
Scheper, W.1
Nijholt, D.A.2
Hoozemans, J.J.3
-
14
-
-
84871576198
-
The heat shock response is modulated by and interferes with toxic effects of scrapie prion protein and amyloid β
-
Resenberger, U. K. et al. The heat shock response is modulated by and interferes with toxic effects of scrapie prion protein and amyloid β. J. Biol. Chem. 287, 43765-43776 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 43765-43776
-
-
Resenberger, U.K.1
-
15
-
-
84857580547
-
Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol
-
Ayala, P. et al. Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol. Exp. Mol. Pathol. 92, 97-104 (2012).
-
(2012)
Exp. Mol. Pathol.
, vol.92
, pp. 97-104
-
-
Ayala, P.1
-
16
-
-
84860693868
-
-
Park, C. S., Cha, H., Kwon, E. J., Sreenivasaiah, P. K. & Kim, D. H. The chemical chaperone 4-phenylbutyric acid attenuates pressure-overload cardiac hypertrophy by alleviating endoplasmic reticulum stress. Biochem. Biophys. Res. Commun. 421, 578-584 (2012).
-
(2012)
The Chemical Chaperone 4-phenylbutyric Acid Attenuates Pressure-overload Cardiac Hypertrophy by Alleviating Endoplasmic Reticulum Stress. Biochem. Biophys. Res. Commun.
, vol.421
, pp. 578-584
-
-
Park, C.S.1
Cha, H.2
Kwon, E.J.3
Sreenivasaiah, P.K.4
Kim, D.H.5
-
17
-
-
79960066445
-
Proteostasis regulation at the endoplasmic reticulum: A new perturbation site for targeted cancer therapy
-
Liu, Y. & Ye, Y. Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy. Cell Res. 21, 867-883 (2011).
-
(2011)
Cell Res.
, vol.21
, pp. 867-883
-
-
Liu, Y.1
Ye, Y.2
-
18
-
-
77957316569
-
Restoring endoplasmic reticulum function by chemical chaperones: An emerging therapeutic approach for metabolic diseases
-
Engin, F. & Hotamisligil, G. S. Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases. Diabetes Obes. Metab. 12 (Suppl. 2), 108-115 (2010).
-
(2010)
Diabetes Obes. Metab.
, vol.12
, Issue.SUPPL. 2
, pp. 108-115
-
-
Engin, F.1
Hotamisligil, G.S.2
-
19
-
-
73849144012
-
The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1α in progression of chronic kidney disease
-
Tanaka, T. & Nangaku, M. The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1α in progression of chronic kidney disease. Curr. Opin. Nephrol. Hypertens. 19, 43-50 (2010).
-
(2010)
Curr. Opin. Nephrol. Hypertens.
, vol.19
, pp. 43-50
-
-
Tanaka, T.1
Nangaku, M.2
-
20
-
-
84885154459
-
Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia
-
Tanaka, T., Yamaguchi, J., Higashijima, Y. & Nangaku, M. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia. FASEB J. 27, 4059-4075 (2013).
-
(2013)
FASEB J.
, vol.27
, pp. 4059-4075
-
-
Tanaka, T.1
Yamaguchi, J.2
Higashijima, Y.3
Nangaku, M.4
-
21
-
-
78649617025
-
Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions
-
Gaikwad, A. B., Gupta, J. & Tikoo, K. Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions. Biochem. J. 432, 333-341 (2010).
-
(2010)
Biochem. J.
, vol.432
, pp. 333-341
-
-
Gaikwad, A.B.1
Gupta, J.2
Tikoo, K.3
-
23
-
-
84864627973
-
Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A
-
Mimura, I. et al. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol. Cell Biol. 32, 3018-3032 (2012).
-
(2012)
Mol. Cell Biol.
, vol.32
, pp. 3018-3032
-
-
Mimura, I.1
-
24
-
-
84864452770
-
Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells
-
Muratsu-Ikeda, S. et al. Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells. PLoS ONE 7, e41462 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Muratsu-Ikeda, S.1
-
25
-
-
79960057790
-
Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma
-
Yang, F. et al. Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma. Neoplasia 13, 590-600 (2011).
-
(2011)
Neoplasia
, vol.13
, pp. 590-600
-
-
Yang, F.1
-
26
-
-
84885188064
-
Hypoxia: A master regulator of microRNA biogenesis and activity
-
Nallamshetty, S., Chan, S. Y. & Loscalzo, J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic. Biol. Med. 64, 20-30 (2013).
-
(2013)
Free Radic. Biol. Med.
, vol.64
, pp. 20-30
-
-
Nallamshetty, S.1
Chan, S.Y.2
Loscalzo, J.3
-
27
-
-
77950362951
-
Hyperglycemia impairs proteasome function by methylglyoxal
-
Queisser, M. A. et al. Hyperglycemia impairs proteasome function by methylglyoxal. Diabetes 59, 670-678 (2010).
-
(2010)
Diabetes
, vol.59
, pp. 670-678
-
-
Queisser, M.A.1
-
28
-
-
65949097068
-
Glyoxalase i overexpression ameliorates renal ischemia-reperfusion injury in rats
-
Kumagai, T. et al. Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats. Am. J. Physiol. Renal Physiol. 296, F912-F921 (2009).
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.296
-
-
Kumagai, T.1
-
29
-
-
81255201280
-
Glyoxalase i retards renal senescence
-
Ikeda, Y. et al. Glyoxalase I retards renal senescence. Am. J. Pathol. 179, 2810-2821 (2011).
-
(2011)
Am. J. Pathol.
, vol.179
, pp. 2810-2821
-
-
Ikeda, Y.1
-
30
-
-
79951664430
-
Inhibitors of advanced glycation and endoplasmic reticulum stress
-
Inagi, R. Inhibitors of advanced glycation and endoplasmic reticulum stress. Methods Enzymol. 491, 361-380 (2011).
-
(2011)
Methods Enzymol.
, vol.491
, pp. 361-380
-
-
Inagi, R.1
-
31
-
-
84863574154
-
Crosstalk between advanced glycation and endoplasmic reticulum stress: Emerging therapeutic targeting for metabolic diseases
-
Piperi, C., Adamopoulos, C., Dalagiorgou, G., Diamanti-Kandarakis, E. & Papavassiliou, A. G. Crosstalk between advanced glycation and endoplasmic reticulum stress: emerging therapeutic targeting for metabolic diseases. J. Clin. Endocrinol. Metab. 97, 2231-2242 (2012).
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
, pp. 2231-2242
-
-
Piperi, C.1
Adamopoulos, C.2
Dalagiorgou, G.3
Diamanti-Kandarakis, E.4
Papavassiliou, A.G.5
-
32
-
-
47549111580
-
Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes
-
Chen, Y. et al. Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes. Am. J. Nephrol. 28, 1014-1022 (2008).
-
(2008)
Am. J. Nephrol.
, vol.28
, pp. 1014-1022
-
-
Chen, Y.1
-
33
-
-
82355175978
-
Kidney aging-inevitable or preventable?
-
Choudhury, D. & Levi, M. Kidney aging-inevitable or preventable? Nat. Rev. Nephrol. 7, 706-717 (2011).
-
(2011)
Nat. Rev. Nephrol.
, vol.7
, pp. 706-717
-
-
Choudhury, D.1
Levi, M.2
-
34
-
-
84869426522
-
Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: A modern paradigm shift
-
Vlassara, H. et al. Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift. J. Gerontol. A Biol. Sci. Med. Sci. 67, 1410-1416 (2012).
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.67
, pp. 1410-1416
-
-
Vlassara, H.1
-
35
-
-
84886994467
-
Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling
-
Liu, J. et al. Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling. Cell. Signal. 26, 110-121 (2013).
-
(2013)
Cell. Signal.
, vol.26
, pp. 110-121
-
-
Liu, J.1
-
36
-
-
84884940660
-
Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster
-
Tsakiri, E. N. et al. Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster. Free Radic. Biol. Med. 65, 1155-1163 (2013).
-
(2013)
Free Radic. Biol. Med.
, vol.65
, pp. 1155-1163
-
-
Tsakiri, E.N.1
-
37
-
-
84879122483
-
Pleiotropic potential of dehydroxymethylepoxyquinomicin for NF-κB suppression via reactive oxygen species and unfolded protein response
-
Nakajima, S. et al. Pleiotropic potential of dehydroxymethylepoxyquinomicin for NF-κB suppression via reactive oxygen species and unfolded protein response. J. Immunol. 190, 6559-6569 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 6559-6569
-
-
Nakajima, S.1
-
38
-
-
75149164455
-
ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBP-β
-
Hayakawa, K. et al. ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBP-β. J. Am. Soc. Nephrol. 21, 73-81 (2010).
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 73-81
-
-
Hayakawa, K.1
-
39
-
-
79959951470
-
Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response
-
Fougeray, S. et al. Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response. Cell Death Dis. 2, e143 (2011).
-
(2011)
Cell Death Dis.
, vol.2
-
-
Fougeray, S.1
-
40
-
-
84880911070
-
Autophagy: Regulation and role in development
-
Hale, A. N., Ledbetter, D. J., Gawriluk, T. R. & Rucker, E. B. Autophagy: regulation and role in development. Autophagy 9, 951-972 (2013).
-
(2013)
Autophagy
, vol.9
, pp. 951-972
-
-
Hale, A.N.1
Ledbetter, D.J.2
Gawriluk, T.R.3
Rucker, E.B.4
-
41
-
-
84879695583
-
The intersecting roles of endoplasmic reticulum stress, ubiquitin-proteasome system, and autophagy in the pathogenesis of proteinuric kidney disease
-
Cybulsky, A. V. The intersecting roles of endoplasmic reticulum stress, ubiquitin-proteasome system, and autophagy in the pathogenesis of proteinuric kidney disease. Kidney Int. 84, 25-33 (2013).
-
(2013)
Kidney Int.
, vol.84
, pp. 25-33
-
-
Cybulsky, A.V.1
-
42
-
-
50249112541
-
Autophagy protects renal tubular cells against cyclosporine toxicity
-
Pallet, N. et al. Autophagy protects renal tubular cells against cyclosporine toxicity. Autophagy 4, 783-791 (2008).
-
(2008)
Autophagy
, vol.4
, pp. 783-791
-
-
Pallet, N.1
-
43
-
-
69249136996
-
Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells
-
Kawakami, T. et al. Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells. Nephrol. Dial. Transplant. 24, 2665-2672 (2009).
-
(2009)
Nephrol. Dial. Transplant.
, vol.24
, pp. 2665-2672
-
-
Kawakami, T.1
-
44
-
-
84887070613
-
Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions
-
Yamahara, K. et al. Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions. J. Am. Soc. Nephrol. 24, 1769-1781 (2013).
-
(2013)
J. Am. Soc. Nephrol.
, vol.24
, pp. 1769-1781
-
-
Yamahara, K.1
-
45
-
-
84881619807
-
Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury
-
Ishihara, M. et al. Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury. Am. J. Physiol. Renal Physiol. 305, F495-F509 (2013).
-
(2013)
Am. J. Physiol. Renal Physiol.
, vol.305
-
-
Ishihara, M.1
-
46
-
-
77955824765
-
An intimate liaison: Spatial organization of the endoplasmic reticulum-mitochondria relationship
-
de Brito, O. M. & Scorrano, L. An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship. EMBO J. 29, 2715-2723 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 2715-2723
-
-
De Brito, O.M.1
Scorrano, L.2
-
47
-
-
84878225746
-
Functional and morphological impact of ER stress on mitochondria
-
Vannuvel, K., Renard, P., Raes, M. & Arnould, T. Functional and morphological impact of ER stress on mitochondria. J. Cell. Physiol. 228, 1802-1818 (2013).
-
(2013)
J. Cell. Physiol.
, vol.228
, pp. 1802-1818
-
-
Vannuvel, K.1
Renard, P.2
Raes, M.3
Arnould, T.4
-
48
-
-
79551600416
-
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
-
Iwasawa, R., Mahul-Mellier, A. L., Datler, C., Pazarentzos, E. & Grimm, S. Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J. 30, 556-568 (2011).
-
(2011)
EMBO J.
, vol.30
, pp. 556-568
-
-
Iwasawa, R.1
Mahul-Mellier, A.L.2
Datler, C.3
Pazarentzos, E.4
Grimm, S.5
-
49
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito, O. M. & Scorrano, L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456, 605-610 (2008).
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
De Brito, O.M.1
Scorrano, L.2
-
50
-
-
84883271527
-
Mfn2 modulates the UPR and mitochondrial function via repression of PERK
-
Muñoz, J. P. et al. Mfn2 modulates the UPR and mitochondrial function via repression of PERK. EMBO J. 32, 2348-2361 (2013).
-
(2013)
EMBO J.
, vol.32
, pp. 2348-2361
-
-
Muñoz, J.P.1
-
51
-
-
84861204926
-
PINK1-and Parkin-mediated mitophagy at a glance
-
Jin, S. M. & Youle, R. J. PINK1-and Parkin-mediated mitophagy at a glance. J. Cell Sci. 125, 795-799 (2012).
-
(2012)
J. Cell Sci.
, vol.125
, pp. 795-799
-
-
Jin, S.M.1
Youle, R.J.2
-
52
-
-
56949089426
-
Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: A molecular mechanism leading to hepatic insulin resistance
-
Lim, J. H., Lee, H. J., Ho Jung, M. & Song, J. Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance. Cell Signal. 21, 169-177 (2009).
-
(2009)
Cell Signal.
, vol.21
, pp. 169-177
-
-
Lim, J.H.1
Lee, H.J.2
Ho Jung, M.3
Song, J.4
-
53
-
-
79960898591
-
Mitochondria and endoplasmic reticulum: Mitochondria-endoplasmic reticulum interplay in type 2 diabetes pathophysiology
-
Rieusset, J. Mitochondria and endoplasmic reticulum: mitochondria- endoplasmic reticulum interplay in type 2 diabetes pathophysiology. Int. J. Biochem. Cell Biol. 43, 1257-1262 (2011).
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 1257-1262
-
-
Rieusset, J.1
-
54
-
-
44049098171
-
Preconditioning with endoplasmic reticulum stress ameliorates mesangioproliferative glomerulonephritis
-
Inagi, R. et al. Preconditioning with endoplasmic reticulum stress ameliorates mesangioproliferative glomerulonephritis. J. Am. Soc. Nephrol. 19, 915-922 (2008).
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 915-922
-
-
Inagi, R.1
-
55
-
-
77956262242
-
Glomerular diseases: Genetic causes and future therapeutics
-
Chiang, C. K. & Inagi, R. Glomerular diseases: genetic causes and future therapeutics. Nat. Rev. Nephrol. 6, 539-554 (2010).
-
(2010)
Nat. Rev. Nephrol.
, vol.6
, pp. 539-554
-
-
Chiang, C.K.1
Inagi, R.2
-
56
-
-
70349648131
-
Glomerular epithelial cell injury associated with mutant α-actinin-4
-
Cybulsky, A. V. et al. Glomerular epithelial cell injury associated with mutant α-actinin-4. Am. J. Physiol. Renal Physiol. 297, F987-F995 (2009).
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.297
-
-
Cybulsky, A.V.1
-
57
-
-
79960961367
-
Regulation of CD2-associated protein influences podocyte endoplasmic reticulum stress-mediated apoptosis induced by albumin overload
-
He, F. et al. Regulation of CD2-associated protein influences podocyte endoplasmic reticulum stress-mediated apoptosis induced by albumin overload. Gene 484, 18-25 (2011).
-
(2011)
Gene
, vol.484
, pp. 18-25
-
-
He, F.1
-
58
-
-
84881093680
-
Laminin β2 gene missense mutation produces endoplasmic reticulum stress in podocytes
-
Chen, Y. M. et al. Laminin β2 gene missense mutation produces endoplasmic reticulum stress in podocytes. J. Am. Soc. Nephrol. 24, 1223-1233 (2013).
-
(2013)
J. Am. Soc. Nephrol.
, vol.24
, pp. 1223-1233
-
-
Chen, Y.M.1
-
59
-
-
77958004302
-
Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids
-
Sieber, J. et al. Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids. Am. J. Physiol. Renal Physiol. 299, F821-F829 (2010).
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Sieber, J.1
-
60
-
-
77951169411
-
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
-
Hartleben, B. et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J. Clin. Invest. 120, 1084-1096 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1084-1096
-
-
Hartleben, B.1
-
61
-
-
79551503342
-
Membranous nephropathy
-
Cybulsky, A. V. Membranous nephropathy. Contrib. Nephrol. 169, 107-125 (2011).
-
(2011)
Contrib. Nephrol.
, vol.169
, pp. 107-125
-
-
Cybulsky, A.V.1
-
62
-
-
32844475054
-
Involvement of endoplasmic reticulum (ER) stress in podocyte injury induced by excessive protein accumulation
-
DOI 10.1111/j.1523-1755.2005.00736.x, PII 4495609
-
Inagi, R. et al. Involvement of endoplasmic reticulum (ER) stress in podocyte injury induced by excessive protein accumulation. Kidney Int. 68, 2639-2650 (2005). (Pubitemid 43251010)
-
(2005)
Kidney International
, vol.68
, Issue.6
, pp. 2639-2650
-
-
Inagi, R.1
Nangaku, M.2
Onogi, H.3
Ueyama, H.4
Kitao, Y.5
Nakazato, K.6
Ogawa, S.7
Kurokawa, K.8
Couser, W.G.9
Miyata, T.10
-
64
-
-
82855161328
-
Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes
-
Chen, S. et al. Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes. Cell Calcium. 50, 523-529 (2011).
-
(2011)
Cell Calcium.
, vol.50
, pp. 523-529
-
-
Chen, S.1
-
65
-
-
80155151897
-
MTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome
-
Ito, N. et al. mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome. Lab. Invest. 91, 1584-1595 (2011).
-
(2011)
Lab. Invest.
, vol.91
, pp. 1584-1595
-
-
Ito, N.1
-
66
-
-
79957927211
-
MTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
-
Inoki, K. et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J. Clin. Invest. 121, 2181-2196 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2181-2196
-
-
Inoki, K.1
-
67
-
-
78349261161
-
TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP 1
-
Morse, E. et al. TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP 1. Am. J. Physiol. Renal Physiol. 299, F965-F972 (2010).
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Morse, E.1
-
68
-
-
33749532327
-
Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells
-
DOI 10.1038/sj.ki.5001704, PII 5001704
-
Ohse, T. et al. Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells. Kidney Int. 70, 1447-1455 (2006). (Pubitemid 44527314)
-
(2006)
Kidney International
, vol.70
, Issue.8
, pp. 1447-1455
-
-
Ohse, T.1
Inagi, R.2
Tanaka, T.3
Ota, T.4
Miyata, T.5
Kojima, I.6
Ingelfinger, J.R.7
Ogawa, S.8
Fujita, T.9
Nangaku, M.10
-
69
-
-
55749105700
-
Proteinuria and hyperglycemia induce endoplasmic reticulum stress
-
Lindenmeyer, M. T. et al. Proteinuria and hyperglycemia induce endoplasmic reticulum stress. J. Am. Soc. Nephrol. 19, 2225-2236 (2008).
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 2225-2236
-
-
Lindenmeyer, M.T.1
-
70
-
-
77956453961
-
Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress
-
Kawakami, T. et al. Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress. Am. J. Physiol. Renal Physiol. 299, F568-F576 (2010).
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Kawakami, T.1
-
71
-
-
84881128520
-
Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity
-
Khan, M. A. et al. Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity. FASEB J. 27, 2946-2956 (2013).
-
(2013)
FASEB J.
, vol.27
, pp. 2946-2956
-
-
Khan, M.A.1
-
72
-
-
9444268084
-
ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death
-
DOI 10.1096/fj.03-1161fje
-
Bando, Y. et al. ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death. FASEB J. 18, 1401-1403 (2004). (Pubitemid 39561594)
-
(2004)
FASEB Journal
, vol.18
, Issue.12
, pp. 1401-1403
-
-
Bando, Y.1
Tsukamoto, Y.2
Katayama, T.3
Ozawa, K.4
Kitao, Y.5
Hori, O.6
Stern, D.M.7
Yamauchi, A.8
Ogawa, S.9
-
73
-
-
84872905488
-
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways
-
Yu, W. et al. Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways. J. Transl. Med. 11, 24 (2013).
-
(2013)
J. Transl. Med.
, vol.11
, pp. 24
-
-
Yu, W.1
-
74
-
-
84883204627
-
Altered unfolded protein response is implicated in the age-related exacerbation of proteinuria-induced proximal tubular cell damage
-
Takeda, N. et al. Altered unfolded protein response is implicated in the age-related exacerbation of proteinuria-induced proximal tubular cell damage. Am. J. Pathol. 183, 774-785 (2013).
-
(2013)
Am. J. Pathol.
, vol.183
, pp. 774-785
-
-
Takeda, N.1
-
76
-
-
57149113728
-
Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
-
Lin, S. L., Kisseleva, T., Brenner, D. A. & Duffield, J. S. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am. J. Pathol. 173, 1617-1627 (2008).
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 1617-1627
-
-
Lin, S.L.1
Kisseleva, T.2
Brenner, D.A.3
Duffield, J.S.4
-
77
-
-
73949096744
-
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
-
Humphreys, B. D. et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am. J. Pathol. 176, 85-97 (2010).
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 85-97
-
-
Humphreys, B.D.1
-
78
-
-
84882289111
-
Origin and function of myofibroblasts in kidney fibrosis
-
LeBleu, V. S. et al. Origin and function of myofibroblasts in kidney fibrosis. Nat. Med. 19, 1047-1053 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1047-1053
-
-
Lebleu, V.S.1
-
79
-
-
82855164039
-
Endoplasmic reticulum stress implicated in the development of renal fibrosis
-
Chiang, C. K. et al. Endoplasmic reticulum stress implicated in the development of renal fibrosis. Mol. Med. 17, 1295-1305 (2011).
-
(2011)
Mol. Med.
, vol.17
, pp. 1295-1305
-
-
Chiang, C.K.1
-
80
-
-
84884179736
-
Secretion of ERP57 is important for extracellular matrix accumulation and progression of renal fibrosis, and is an early sign of disease onset
-
Dihazi, H. et al. Secretion of ERP57 is important for extracellular matrix accumulation and progression of renal fibrosis, and is an early sign of disease onset. J. Cell Sci. 126, 3649-3663 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3649-3663
-
-
Dihazi, H.1
-
81
-
-
84885060233
-
Plasticity of renal erythropoietin-producing cells governs fibrosis
-
Souma, T. et al. Plasticity of renal erythropoietin-producing cells governs fibrosis. J. Am. Soc. Nephrol. 24, 1599-1616 (2013).
-
(2013)
J. Am. Soc. Nephrol.
, vol.24
, pp. 1599-1616
-
-
Souma, T.1
-
82
-
-
0036832772
-
Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-κB
-
La Ferla, K., Reimann, C., Jelkmann, W. & Hellwig-Bürgel, T. Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-κB. FASEB J. 16, 1811-1813 (2002).
-
(2002)
FASEB J.
, vol.16
, pp. 1811-1813
-
-
La Ferla, K.1
Reimann, C.2
Jelkmann, W.3
Hellwig-Bürgel, T.4
-
83
-
-
84874084181
-
Endoplasmic reticulum stress signal impairs erythropoietin production: A role for ATF4
-
Chiang, C. K., Nangaku, M., Tanaka, T., Iwawaki, T. & Inagi, R. Endoplasmic reticulum stress signal impairs erythropoietin production: a role for ATF4. Am. J. Physiol. Cell Physiol. 304, C342-C353 (2013).
-
(2013)
Am. J. Physiol. Cell Physiol.
, vol.304
-
-
Chiang, C.K.1
Nangaku, M.2
Tanaka, T.3
Iwawaki, T.4
Inagi, R.5
-
84
-
-
77955199612
-
Heat shock proteins: Cellular and molecular mechanisms in the central nervous system
-
Stetler, R. A. et al. Heat shock proteins: cellular and molecular mechanisms in the central nervous system. Prog. Neurobiol. 92, 184-211 (2010).
-
(2010)
Prog. Neurobiol.
, vol.92
, pp. 184-211
-
-
Stetler, R.A.1
-
85
-
-
79960652801
-
Molecular chaperones in protein folding and proteostasis
-
Hartl, F. U., Bracher, A. & Hayer-Hartl, M. Molecular chaperones in protein folding and proteostasis. Nature 475, 324-332 (2011).
-
(2011)
Nature
, vol.475
, pp. 324-332
-
-
Hartl, F.U.1
Bracher, A.2
Hayer-Hartl, M.3
-
86
-
-
84883329568
-
In vivo activating transcription factor 3 silencing ameliorates the AMPK compensatory effects for ER stress-mediated β cell dysfunction during the progression of type 2 diabetes
-
Kim, J. Y. et al. In vivo activating transcription factor 3 silencing ameliorates the AMPK compensatory effects for ER stress-mediated β cell dysfunction during the progression of type 2 diabetes. Cell. Signal. 25, 2348-2361 (2013).
-
(2013)
Cell. Signal.
, vol.25
, pp. 2348-2361
-
-
Kim, J.Y.1
-
88
-
-
84875143788
-
Targeting endoplasmic reticulum stress in metabolic disease
-
Cao, S. S. & Kaufman, R. J. Targeting endoplasmic reticulum stress in metabolic disease. Expert Opin. Ther. Targets 17, 437-448 (2013).
-
(2013)
Expert Opin. Ther. Targets
, vol.17
, pp. 437-448
-
-
Cao, S.S.1
Kaufman, R.J.2
-
89
-
-
3042623796
-
Defective trafficking of nephrin missense mutants rescued by a chemical chaperone
-
DOI 10.1097/01.ASN.0000129826.28932.FD
-
Liu, X. L. et al. Defective trafficking of nephrin missense mutants rescued by a chemical chaperone. J. Am. Soc. Nephrol. 15, 1731-1738 (2004). (Pubitemid 38822051)
-
(2004)
Journal of the American Society of Nephrology
, vol.15
, Issue.7
, pp. 1731-1738
-
-
Liu, X.L.1
Done, S.C.2
Yan, K.3
Kilpelainen, P.4
Pikkarainen, T.5
Tryggvason, K.6
-
90
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
DOI 10.1101/gad.1250704
-
Marciniak, S. J. et al. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev. 18, 3066-3077 (2004). (Pubitemid 39658175)
-
(2004)
Genes and Development
, vol.18
, Issue.24
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
91
-
-
84877578475
-
ER stress induced transcriptional regulation increases protein synthesis leading to cell death
-
Han, J. et al. ER stress induced transcriptional regulation increases protein synthesis leading to cell death. Nat. Cell Biol. 15, 481-490 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 481-490
-
-
Han, J.1
-
92
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley, D. Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78, 477-513 (2009).
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
93
-
-
84861783400
-
Ubiquitin-binding proteins: Decoders of ubiquitin-mediated cellular functions
-
Husnjak, K. & Dikic, I. Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. Annu. Rev. Biochem. 81, 291-322 (2012).
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 291-322
-
-
Husnjak, K.1
Dikic, I.2
-
94
-
-
77958487260
-
Cellular strategies for controlling protein aggregation
-
Tyedmers, J., Mogk, A. & Bukau, B. Cellular strategies for controlling protein aggregation. Nat. Rev. Mol. Cell Biol. 11, 777-788 (2010).
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 777-788
-
-
Tyedmers, J.1
Mogk, A.2
Bukau, B.3
-
95
-
-
84863313893
-
Cellular strategies of protein quality control
-
Chen, B., Retzlaff, M., Roos, T. & Frydman, J. Cellular strategies of protein quality control. Cold Spring Harb. Perspect. Biol. 3, a004374 (2011).
-
(2011)
Cold Spring Harb. Perspect. Biol.
, vol.3
-
-
Chen, B.1
Retzlaff, M.2
Roos, T.3
Frydman, J.4
-
96
-
-
84863903065
-
Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: Progress and prognosis
-
Lindquist, S. L. & Kelly, J. W. Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis. Cold Spring Harb. Perspect. Biol. 3, a004507 (2011).
-
(2011)
Cold Spring Harb. Perspect. Biol.
, vol.3
-
-
Lindquist, S.L.1
Kelly, J.W.2
-
97
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan, U. et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313, 1137-1140 (2006). (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
98
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
Ozcan, L. et al. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab. 9, 35-51 (2009).
-
(2009)
Cell Metab.
, vol.9
, pp. 35-51
-
-
Ozcan, L.1
-
99
-
-
77953719527
-
Effects of 4 phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: Regulation of endoplasmic reticulum stress-oxidative activation
-
Luo, Z. F. et al. Effects of 4 phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: regulation of endoplasmic reticulum stress-oxidative activation. Toxicol. Appl. Pharmacol. 246, 49-57 (2010).
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.246
, pp. 49-57
-
-
Luo, Z.F.1
-
100
-
-
84866148163
-
Chemical chaperones curcumin and 4 phenylbutyric acid improve secretion of mutant factor H R127H by fibroblasts from a factor H deficient patient
-
Albuquerque, J. A., Lamers, M. L., Castiblanco-Valencia, M. M., Dos Santos, M. & Isaac, L. Chemical chaperones curcumin and 4 phenylbutyric acid improve secretion of mutant factor H R127H by fibroblasts from a factor H deficient patient. J. Immunol. 189, 3242-3248 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 3242-3248
-
-
Albuquerque, J.A.1
Lamers, M.L.2
Castiblanco-Valencia, M.M.3
Dos Santos, M.4
Isaac, L.5
-
101
-
-
84871137381
-
Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice
-
Wang, J. Q. et al. Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice. Toxicol. Appl. Pharmacol. 266, 307-316 (2013).
-
(2013)
Toxicol. Appl. Pharmacol.
, vol.266
, pp. 307-316
-
-
Wang, J.Q.1
-
102
-
-
84875551638
-
Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells
-
Omura, T. et al. Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells. Biochem. Biophys. Res. Commun. 432, 689-694 (2013).
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.432
, pp. 689-694
-
-
Omura, T.1
-
103
-
-
38049170584
-
A molecular chaperone inducer protects neurons from ER stress
-
Kudo, T. et al. A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ. 15, 364-375 (2008).
-
(2008)
Cell Death Differ.
, vol.15
, pp. 364-375
-
-
Kudo, T.1
-
104
-
-
65449117250
-
The protective effect of a newly developed molecular chaperone-inducer against mouse ischemic acute kidney injury
-
Prachasilchai, W. et al. The protective effect of a newly developed molecular chaperone-inducer against mouse ischemic acute kidney injury. J. Pharmacol. Sci. 109, 311-314 (2009).
-
(2009)
J. Pharmacol. Sci.
, vol.109
, pp. 311-314
-
-
Prachasilchai, W.1
-
105
-
-
67349151270
-
The pharmacological chaperone 1 deoxygalactonojirimycin increases α-galactosidase A levels in Fabry patient cell lines
-
Benjamin, E. R. et al. The pharmacological chaperone 1 deoxygalactonojirimycin increases α-galactosidase A levels in Fabry patient cell lines. J. Inherit. Metab. Dis. 32, 424-440 (2009).
-
(2009)
J. Inherit. Metab. Dis.
, vol.32
, pp. 424-440
-
-
Benjamin, E.R.1
-
106
-
-
84869875424
-
Safety and pharmacodynamic effects of a pharmacological chaperone on α galactosidase A activity and globotriaosylceramide clearance in Fabry disease: Report from two phase 2 clinical studies
-
Germain, D. P. et al. Safety and pharmacodynamic effects of a pharmacological chaperone on α galactosidase A activity and globotriaosylceramide clearance in Fabry disease: report from two phase 2 clinical studies. Orphanet J. Rare Dis. 7, 91 (2012).
-
(2012)
Orphanet J. Rare Dis.
, vol.7
, pp. 91
-
-
Germain, D.P.1
-
107
-
-
84876084462
-
A Phase 2 study of migalastat hydrochloride in females with Fabry disease: Selection of population, safety and pharmacodynamic effects
-
Giugliani, R. et al. A Phase 2 study of migalastat hydrochloride in females with Fabry disease: selection of population, safety and pharmacodynamic effects. Mol. Genet. Metab. 109, 86-92 (2013).
-
(2013)
Mol. Genet. Metab.
, vol.109
, pp. 86-92
-
-
Giugliani, R.1
-
108
-
-
84885463900
-
Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice
-
Moreno, J. A. et al. Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. Sci. Transl. Med. 5, 206ra138 (2013).
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Moreno, J.A.1
-
109
-
-
84876117324
-
Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury
-
Fang, L. et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS ONE 8, e60546 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Fang, L.1
-
110
-
-
53749105061
-
Cyclosporine-induced endoplasmic reticulum stress triggers tubular phenotypic changes and death
-
Pallet, N. et al. Cyclosporine-induced endoplasmic reticulum stress triggers tubular phenotypic changes and death. Am. J. Transplant. 8, 2283-2296 (2008).
-
(2008)
Am. J. Transplant.
, vol.8
, pp. 2283-2296
-
-
Pallet, N.1
-
111
-
-
58849154101
-
Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: A role for endothelial phenotypic changes and death
-
Bouvier, N. et al. Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death. Am. J. Physiol. Renal Physiol. 296, F160-F169 (2009).
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.296
-
-
Bouvier, N.1
-
112
-
-
0020545855
-
Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension
-
Holmes, B., Brogden, R. N., Heel, R. C., Speight, T. M. & Avery, G. S. Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. Drugs 26, 212-229 (1983). (Pubitemid 13033177)
-
(1983)
Drugs
, vol.26
, Issue.3
, pp. 212-229
-
-
Holmes, B.1
Brogden, R.N.2
Heel, R.C.3
-
113
-
-
79953288480
-
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis
-
Tsaytler, P., Harding, H. P., Ron, D. & Bertolotti, A. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 332, 91-94 (2011).
-
(2011)
Science
, vol.332
, pp. 91-94
-
-
Tsaytler, P.1
Harding, H.P.2
Ron, D.3
Bertolotti, A.4
-
114
-
-
43049176634
-
Health effects of quercetin: From antioxidant to nutraceutical
-
Boots, A. W., Haenen, G. R. & Bast, A. Health effects of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol. 585, 325-337 (2008).
-
(2008)
Eur. J. Pharmacol.
, vol.585
, pp. 325-337
-
-
Boots, A.W.1
Haenen, G.R.2
Bast, A.3
-
115
-
-
84873617056
-
Protective effect of quercetin on lead-induced oxidative stress and endoplasmic reticulum stress in rat liver via the IRE1/JNK and PI3K/Akt pathway
-
Liu, C. M., Zheng, G. H., Ming, Q. L., Sun, J. M. & Cheng, C. Protective effect of quercetin on lead-induced oxidative stress and endoplasmic reticulum stress in rat liver via the IRE1/JNK and PI3K/Akt pathway. Free Radic. Res. 47, 192-201 (2013).
-
(2013)
Free Radic. Res.
, vol.47
, pp. 192-201
-
-
Liu, C.M.1
Zheng, G.H.2
Ming, Q.L.3
Sun, J.M.4
Cheng, C.5
-
116
-
-
0032558167
-
Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: A new class of renoprotective agents
-
DOI 10.1097/00007890-199807270-00001
-
Shoskes, D. A. Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents. Transplantation 66, 147-152 (1998). (Pubitemid 28369991)
-
(1998)
Transplantation
, vol.66
, Issue.2
, pp. 147-152
-
-
Shoskes, D.A.1
-
117
-
-
60549084713
-
A new role for the neuronal ubiquitin C terminal hydrolase L1 (UCH L1) in podocyte process formation and podocyte injury in human glomerulopathies
-
Meyer-Schwesinger, C. et al. A new role for the neuronal ubiquitin C terminal hydrolase L1 (UCH L1) in podocyte process formation and podocyte injury in human glomerulopathies. J. Pathol. 217, 452-464 (2009).
-
(2009)
J. Pathol.
, vol.217
, pp. 452-464
-
-
Meyer-Schwesinger, C.1
-
118
-
-
80053452602
-
Bortezomib: Killing two birds with one stone in gastrointestinal stromal tumors
-
Duensing, S. & Duensing, A. Bortezomib: killing two birds with one stone in gastrointestinal stromal tumors. Oncotarget 1, 6-8 (2010).
-
(2010)
Oncotarget
, vol.1
, pp. 6-8
-
-
Duensing, S.1
Duensing, A.2
-
119
-
-
84862841567
-
Impact of bortezomib on bone health in myeloma: A review of current evidence
-
Zangari, M., Terpos, E., Zhan, F. & Tricot, G. Impact of bortezomib on bone health in myeloma: a review of current evidence. Cancer Treat. Rev. 38, 968-980 (2012).
-
(2012)
Cancer Treat. Rev.
, vol.38
, pp. 968-980
-
-
Zangari, M.1
Terpos, E.2
Zhan, F.3
Tricot, G.4
-
120
-
-
84859509851
-
Proteasome inhibition with bortezomib: An effective therapy for severe antibody mediated rejection after renal transplantation
-
Sureshkumar, K. K. et al. Proteasome inhibition with bortezomib: an effective therapy for severe antibody mediated rejection after renal transplantation. Clin. Nephrol. 77, 246-253 (2012).
-
(2012)
Clin. Nephrol.
, vol.77
, pp. 246-253
-
-
Sureshkumar, K.K.1
-
121
-
-
84870188596
-
The use of bortezomib as a rescue treatment for acute antibody-mediated rejection: Report of three cases and review of literature
-
Tzvetanov, I. et al. The use of bortezomib as a rescue treatment for acute antibody-mediated rejection: report of three cases and review of literature. Transplant. Proc. 44, 2971-2975 (2012).
-
(2012)
Transplant. Proc.
, vol.44
, pp. 2971-2975
-
-
Tzvetanov, I.1
-
122
-
-
77956397164
-
Angiotensin i converting enzyme Gln1069Arg mutation impairs trafficking to the cell surface resulting in selective denaturation of the C domain
-
Danilov, S. M. et al. Angiotensin I converting enzyme Gln1069Arg mutation impairs trafficking to the cell surface resulting in selective denaturation of the C domain. PLoS ONE 5, e10438 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Danilov, S.M.1
-
123
-
-
84870864069
-
The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4
-
Zang, Y. et al. The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4. Autophagy 8, 1873-1874 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 1873-1874
-
-
Zang, Y.1
-
124
-
-
79955661493
-
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver
-
Li, Y. et al. Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. FASEB J. 25, 1664-1679 (2011).
-
(2011)
FASEB J.
, vol.25
, pp. 1664-1679
-
-
Li, Y.1
-
125
-
-
84861712572
-
SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150
-
Jung, T. W., Lee, K. T., Lee, M. W. & Ka, K. H. SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150. Biochem. Biophys. Res. Commun. 422, 229-232 (2012).
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.422
, pp. 229-232
-
-
Jung, T.W.1
Lee, K.T.2
Lee, M.W.3
Ka, K.H.4
-
126
-
-
79551474362
-
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation
-
Wang, F. M., Chen, Y. J. & Ouyang, H. J. Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation. Biochem. J. 433, 245-252 (2011).
-
(2011)
Biochem. J.
, vol.433
, pp. 245-252
-
-
Wang, F.M.1
Chen, Y.J.2
Ouyang, H.J.3
|