The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice

Pharmacological Research

Volumn 99, Issue , 2015, Pages 52-62

  Tanaka, Yuta ^a   Ishitsuka, Yoichi ^a   Hayasaka, Marina ^a   Yamada, Yusei ^a   Miyata, Keishi ^b   Endo, Motoyoshi ^b   Kondo, Yuki ^a   Moriuchi, Hiroshi ^c   Irikura, Mitsuru ^d   Tanaka, Ken Ichiro ^e   Mizushima, Tohru ^e   Oike, Yuichi ^b   Irie, Tetsumi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c SOJO UNIVERSITY   (Japan)

^d DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^e KEIO UNIVERSITY   (Japan)

Author keywords

Bleomycin; CHOP; Ddit3; Endoplasmic reticulum stress; Pulmonary fibrosis; Tauroursodeoxycholic acid

Indexed keywords

BLEOMYCIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; TAUROURSODEOXYCHOLIC ACID; DDIT3 PROTEIN, MOUSE; TAUROCHENODEOXYCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CASPASE 11 GENE; CHOP GENE; CONTROLLED STUDY; DISEASE EXACERBATION; DOSE RESPONSE; ENDOPLASMIC RETICULUM STRESS; GENE; GENE EXPRESSION; INTERLEUKIN 1BETA GENE; LUNG FIBROSIS; LUNG LAVAGE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; LUNG; METABOLISM; PATHOLOGY; PHYSIOLOGY; PULMONARY FIBROSIS;

ANIMALS; APOPTOSIS; BLEOMYCIN; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PULMONARY FIBROSIS; RNA, MESSENGER; TAUROCHENODEOXYCHOLIC ACID; TRANSCRIPTION FACTOR CHOP;

EID: 84930948378     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2015.05.004     Document Type: Article

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