Methods for monitoring endoplasmic reticulum stress and the unfolded protein response

International Journal of Cell Biology

Volumn , Issue , 2010, Pages

  Gupta, Sanjeev ^a   Samali, Afshin ^a   Fitzgerald, Una ^a   Deegan, Shane ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE;

ASSAY; CELL ACTIVATION; ENDOPLASMIC RETICULUM STRESS; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN PROCESSING; REVIEW;

EID: 77955979773     PISSN: 16878876     EISSN: 16878884     Source Type: Journal    
DOI: 10.1155/2010/830307     Document Type: Review

References (42)

1. Ron D., Walter P., Signal integration in the endoplasmic reticulum unfolded protein response Nature Reviews Molecular Cell Biology 2007 8 7 519 529
2. Schroder M., Kaufman R. J., The mammalian unfolded protein response Annual Review of Biochemistry 2005 74 739 789
3. Malhotra J. D., Kaufman R. J., The endoplasmic reticulum and the unfolded protein response Seminars in Cell and Developmental Biology 2007 18 6 716 731
4. Oikawa D., Kimata Y., Takeuchi M., Kohno K., An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1 Biochemical Journal 2005 391 1 135 142
5. Oikawa D., Kimata Y., Kohno K., Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1 Journal of Cell Science 2007 120 9 1681 1688
6. Credle J. J., Finer-Moore J. S., Papa F. R., Stroud R. M., Walter P., On the mechanism of sensing unfolded protein in the endoplasmic reticulum Proceedings of the National Academy of Sciences of the United States of America 2005 102 52 18773 18784
7. Kimata Y., Ishiwata-Kimata Y., Ito T., Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins Journal of Cell Biology 2007 179 1 75 86
8. Zhou J., Liu C. Y., Back S. H., The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response Proceedings of the National Academy of Sciences of the United States of America 2006 103 39 14343 14348
9. Oikawa D., Kimata Y., Kohno K., Iwawaki T., Activation of mammalian IRE1 upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins Experimental Cell Research 2009 315 15 2496 2504
10. Nadanaka S., Okada T., Yoshida H., Mori K., Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress Molecular and Cellular Biology 2007 27 3 1027 1043
11. Shen J., Chen X., Hendershot L., Prywes R., ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals Developmental Cell 2002 3 1 99 111
12. Harding H. P., Zhang Y., Bertolotti A., Zeng H., Ron D., Perk is essential for translational regulation and cell survival during the unfolded protein response Molecular Cell 2000 5 5 897 904
13. Jiang H.-Y., Wek R. C., Phosphorylation of the -subunit of the eukaryotic initiation factor-2 (eIF2 ) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition Journal of Biological Chemistry 2005 280 14 14189 14202
14. Harding H. P., Zhang Y., Zeng H., An integrated stress response regulates amino acid metabolism and resistance to oxidative stress Molecular Cell 2003 11 3 619 633
15. Calfon M., Zeng H., Urano F., IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA Nature 2002 415 6867 92 96
16. Lee A.-H., Iwakoshi N. N., Glimcher L. H., XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response Molecular and Cellular Biology 2003 23 21 7448 7459
17. Haze K., Yoshida H., Yanagi H., Yura T., Mori K., Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress Molecular Biology of the Cell 1999 10 11 3787 3799
18. Wu J., Rutkowski D. T., Dubois M., ATF6 optimizes long-term endoplasmic reticulum function to protect cells from chronic stress Developmental Cell 2007 13 3 351 364
19. Yamamoto K., Sato T., Matsui T., Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6 and XBP1 Developmental Cell 2007 13 3 365 376
20. Ogata M., Hino S.-I., Saito A., Autophagy is activated for cell survival after endoplasmic reticulum stress Molecular and Cellular Biology 2006 26 24 9220 9231
21. Levine B., Kroemer G., Autophagy in aging, disease and death: the true identity of a cell death impostor Cell Death and Differentiation 2009 16 1 1 2
22. Wang X.-Z., Lawson B., Brewer J. W., Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153) Molecular and Cellular Biology 1996 16 8 4273 4280
23. Wang X.-Z., Ron D., Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase Science 1996 272 5266 1347 1349
24. Haataja L., Gurlo T., Huang C.-J., Butler P. C., Many commercially available antibodies for detection of CHOP expression as a marker of endoplasmic reticulum stress fail specificity evaluation Cell Biochemistry and Biophysics 2008 51 2-3 105 107
25. Lin J. H., Walter P., Yen T. S. B., Endoplasmic reticulum stress in disease pathogenesis Annual Review of Pathology: Mechanisms of Disease 2008 3 399 425
26. Kim I., Xu W., Reed J. C., Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities Nature Reviews Drug Discovery 2008 7 12 1013 1030
27. Kokame K., Kato H., Miyata T., Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response Journal of Biological Chemistry 2001 276 12 9199 9205
28. Roy B., Lee A. S., The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex Nucleic Acids Research 1999 27 6 1437 1443
29. Wang Y., Shen J., Arenzana N., Tirasophon W., Kaufman R. J., Prywes R., Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response Journal of Biological Chemistry 2000 275 35 27013 27020
30. Yamamoto K., Yoshida H., Kokame K., Kaufman R. J., Mori K., Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II Journal of Biochemistry 2004 136 3 343 350
31. Yoshida H., Haze K., Yanagi H., Yura T., Mori K., Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins: involvement of basic leucine zipper transcription factors Journal of Biological Chemistry 1998 273 50 33741 33749
32. Hayashi T., Saito A., Okuno S., Oxidative damage to the endoplasmic reticulum is implicated in ischemic neuronal cell death Journal of Cerebral Blood Flow and Metabolism 2003 23 10 1117 1128
33. Unterberger U., Hoftberger R., Gelpi E., Flicker H., Budka H., Voigtlander T., Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo Journal of Neuropathology and Experimental Neurology 2006 65 4 348 357
34. Hoozemans J. J. M., Veerhuis R., Van Haastert E. S., The unfolded protein response is activated in Alzheimers disease Acta Neuropathologica 2005 110 2 165 172
35. Mhaille A. N., McQuaid S., Windebank A., Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions Journal of Neuropathology and Experimental Neurology 2008 67 3 200 211
36. Iwawaki T., Akai R., Kohno K., Miura M., A transgenic mouse model for monitoring endoplasmic reticulum stress Nature Medicine 2004 10 1 98 102
37. Brunsing R., Omori S. A., Weber F., B- and T-cell development both involve activity of the unfolded protein response pathway Journal of Biological Chemistry 2008 283 26 17954 17961
38. Chen X., Shen J., Prywes R., The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the er to the Golgi Journal of Biological Chemistry 2002 277 15 13045 13052
39. Nadanaka S., Yoshida H., Kano F., Murata M., Mori K., Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum Molecular Biology of the Cell 2004 15 6 2537 2548
40. Reimold A. M., Iwakoshi N. N., Manis J., Plasma cell differentiation requires the transcription factor XBP-1 Nature 2001 412 6844 300 307
41. Shen X., Ellis R. E., Lee K., Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development Cell 2001 107 7 893 903
42. Mao C., Tai W.-C., Bai Y., Poizat C., Lee A. S., In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4 Journal of Biological Chemistry 2006 281 13 8877 8887