메뉴 건너뛰기




Volumn 212, Issue 2, 2007, Pages 498-508

Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; CELL PROTEIN; PROTEIN DLP1; PROTEIN DRP1; THAPSIGARGIN; UNCLASSIFIED DRUG;

EID: 34347386472     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21051     Document Type: Article
Times cited : (114)

References (33)
  • 1
    • 0028047262 scopus 로고
    • Dynamics of mitochondria in living cells; shape changes, dislocation, fusion, and fission of mitochondria
    • Bereiter-Hahn J, Voth M. 1994. Dynamics of mitochondria in living cells; shape changes, dislocation, fusion, and fission of mitochondria. Microsc Res Tech 27: 198-219.
    • (1994) Microsc Res Tech , vol.27 , pp. 198-219
    • Bereiter-Hahn, J.1    Voth, M.2
  • 3
    • 0037417334 scopus 로고    scopus 로고
    • Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
    • Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC. 2003. Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol 160:1115-1127.
    • (2003) J Cell Biol , vol.160 , pp. 1115-1127
    • Breckenridge, D.G.1    Stojanovic, M.2    Marcellus, R.C.3    Shore, G.C.4
  • 5
    • 17144429793 scopus 로고    scopus 로고
    • Mitochondrial function and actin regulate dynamin-related protein I-dependent mitochondrial fission
    • De Vos KJ, Allan VJ, Grierson AJ, Sheetz MP. 2005. Mitochondrial function and actin regulate dynamin-related protein I-dependent mitochondrial fission. Curr Biol 15:678-683.
    • (2005) Curr Biol , vol.15 , pp. 678-683
    • De Vos, K.J.1    Allan, V.J.2    Grierson, A.J.3    Sheetz, M.P.4
  • 8
    • 0037459089 scopus 로고    scopus 로고
    • Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells
    • Ishihara N, Jofuku A, Eura Y, Mihara K. 2003, Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells. Biochem Biophys Res Commun 301:891-898.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 891-898
    • Ishihara, N.1    Jofuku, A.2    Eura, Y.3    Mihara, K.4
  • 9
    • 0141592470 scopus 로고    scopus 로고
    • hFis1, a novel component of the mammalian mitochondrial fission machinery
    • James DI, Parone PA, Mattenberger Y, Martinou JC. 2003. hFis1, a novel component of the mammalian mitochondrial fission machinery. J Biol Chem 278:36373-36379.
    • (2003) J Biol Chem , vol.278 , pp. 36373-36379
    • James, D.I.1    Parone, P.A.2    Mattenberger, Y.3    Martinou, J.C.4
  • 10
    • 0028180546 scopus 로고
    • 2+ signals activate apoptosis in thymocytes: Studies using the Ca(2+)-ATPase inhibitor thapsigargin
    • 2+ signals activate apoptosis in thymocytes: studies using the Ca(2+)-ATPase inhibitor thapsigargin. Exp Cell Res 212:84-92.
    • (1994) Exp Cell Res , vol.212 , pp. 84-92
    • Jiang, S.1    Chow, S.C.2    Nicotera, P.3    Orrenius, S.4
  • 11
    • 0028339255 scopus 로고
    • Thapsigargin-induced persistent intracellular calcium pool depletion and apoptosis in human hepatoma cells
    • Kaneko Y, Tsukamoto A. 1994. Thapsigargin-induced persistent intracellular calcium pool depletion and apoptosis in human hepatoma cells. Cancer Lett 79:147-155.
    • (1994) Cancer Lett , vol.79 , pp. 147-155
    • Kaneko, Y.1    Tsukamoto, A.2
  • 14
    • 6344274848 scopus 로고    scopus 로고
    • Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
    • Lee YJ, Jeong SY, Karbowski M, Smith CL, Youle RJ. 2004. Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell 15:5001-5011.
    • (2004) Mol Biol Cell , vol.15 , pp. 5001-5011
    • Lee, Y.J.1    Jeong, S.Y.2    Karbowski, M.3    Smith, C.L.4    Youle, R.J.5
  • 15
    • 0036906665 scopus 로고    scopus 로고
    • Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
    • Legros F, Lombes A, Frachon P, Rojo M. 2002. Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell 13:4343-4354.
    • (2002) Mol Biol Cell , vol.13 , pp. 4343-4354
    • Legros, F.1    Lombes, A.2    Frachon, P.3    Rojo, M.4
  • 17
    • 0020565625 scopus 로고
    • Ruthenium Red inhibits the activation of pyruvate dehydrogenase caused by positive inotropic agents in the perfused rat heart
    • McCormack JG, England PJ. 1983. Ruthenium Red inhibits the activation of pyruvate dehydrogenase caused by positive inotropic agents in the perfused rat heart. Biochem J 214:581-585.
    • (1983) Biochem J , vol.214 , pp. 581-585
    • McCormack, J.G.1    England, P.J.2
  • 18
    • 0028177231 scopus 로고
    • 2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane
    • 2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane. Biochem J 300:665-672.
    • (1994) Biochem J , vol.300 , pp. 665-672
    • Morgan, A.J.1    Jacob, R.2
  • 19
    • 0032734577 scopus 로고    scopus 로고
    • The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells
    • Pitts KR, Yoon Y, Krueger EW, McNiven MA. 1999. The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells. Mol Biol Cell 10:4403-4417.
    • (1999) Mol Biol Cell , vol.10 , pp. 4403-4417
    • Pitts, K.R.1    Yoon, Y.2    Krueger, E.W.3    McNiven, M.A.4
  • 20
    • 0033571410 scopus 로고    scopus 로고
    • Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape
    • Sesaki H, Jensen RE. 1999. Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J Cell Biol 147:699-706.
    • (1999) J Cell Biol , vol.147 , pp. 699-706
    • Sesaki, H.1    Jensen, R.E.2
  • 22
    • 0035166814 scopus 로고    scopus 로고
    • Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
    • Smirnova E, Griparic L, Shurland DL, van der Bliek AM. 2001. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell 12:2245-2256.
    • (2001) Mol Biol Cell , vol.12 , pp. 2245-2256
    • Smirnova, E.1    Griparic, L.2    Shurland, D.L.3    van der Bliek, A.M.4
  • 23
    • 1842479419 scopus 로고    scopus 로고
    • Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology
    • Stojanovski D, Koutsopoulos OS, Okamoto K, Ryan MT. 2004. Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J Cell Sci 117:1201-1210.
    • (2004) J Cell Sci , vol.117 , pp. 1201-1210
    • Stojanovski, D.1    Koutsopoulos, O.S.2    Okamoto, K.3    Ryan, M.T.4
  • 25
    • 3843125367 scopus 로고    scopus 로고
    • Knockdown of MTP18, a novel phosphatidyl inositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis
    • Tondera D, Santel A, Schwarzer R, Dames S, Giese K, Klippel A, Kaufmann J. 2004. Knockdown of MTP18, a novel phosphatidyl inositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis. J Biol Chem 279: 31544-31555.
    • (2004) J Biol Chem , vol.279 , pp. 31544-31555
    • Tondera, D.1    Santel, A.2    Schwarzer, R.3    Dames, S.4    Giese, K.5    Klippel, A.6    Kaufmann, J.7
  • 26
    • 0031960313 scopus 로고    scopus 로고
    • A tool coming of age: Thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases
    • Treiman M, Caspersen C, Christensen SB. 1998. A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases. Trends Pharmacol Sci 19:131-135.
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 131-135
    • Treiman, M.1    Caspersen, C.2    Christensen, S.B.3
  • 28
    • 0036308235 scopus 로고    scopus 로고
    • Merging mitochondria matters: Cellular role and molecular machinery of mitochondrial fusion
    • Westermann B. 2002. Merging mitochondria matters: cellular role and molecular machinery of mitochondrial fusion. EMBO Rep 3:527-531.
    • (2002) EMBO Rep , vol.3 , pp. 527-531
    • Westermann, B.1
  • 30
    • 0035166812 scopus 로고    scopus 로고
    • Mammalian dynamin-like protein DLP1 tubulates membranes
    • Yoon Y, Pitts KR, McNiven MA. 2001. Mammalian dynamin-like protein DLP1 tubulates membranes. Mol Biol Cell 12:2894-2905.
    • (2001) Mol Biol Cell , vol.12 , pp. 2894-2905
    • Yoon, Y.1    Pitts, K.R.2    McNiven, M.A.3
  • 31
    • 0043092647 scopus 로고    scopus 로고
    • The mitochondrial protein hFis 1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
    • Yoon Y, Krueger EW, Oswald BJ, McNiven MA. 2003. The mitochondrial protein hFis 1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol Cell Biol 23:5409-5420.
    • (2003) Mol Cell Biol , vol.23 , pp. 5409-5420
    • Yoon, Y.1    Krueger, E.W.2    Oswald, B.J.3    McNiven, M.A.4
  • 32
    • 27144477744 scopus 로고    scopus 로고
    • Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1
    • Yu T, Fox RJ, Burwell LS, Yoon Y. 2005. Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1. J Cell Sci 118:4141-4151.
    • (2005) J Cell Sci , vol.118 , pp. 4141-4151
    • Yu, T.1    Fox, R.J.2    Burwell, L.S.3    Yoon, Y.4
  • 33
    • 33644552417 scopus 로고    scopus 로고
    • Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
    • Yu T, Robotham JL, Yoon Y. 2006. Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci USA 103:2653-2658.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2653-2658
    • Yu, T.1    Robotham, J.L.2    Yoon, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.