-
1
-
-
10444226462
-
ER stress and the unfolded protein response
-
Schroder, M., and Kaufman, R.J. 2005. ER stress and the unfolded protein response. Mutat. Res. 569:29-63.
-
(2005)
Mutat. Res.
, vol.569
, pp. 29-63
-
-
Schroder, M.1
Kaufman, R.J.2
-
2
-
-
4444232905
-
The unfolded protein response: A stress signaling pathway of the endoplasmic reticulum
-
Shen, X., Zhang, K., and Kaufman, R.J. 2004. The unfolded protein response: a stress signaling pathway of the endoplasmic reticulum [review]. J. Chem. Neuroanat. 28:79-92.
-
(2004)
J. Chem. Neuroanat.
, vol.28
, pp. 79-92
-
-
Shen, X.1
Zhang, K.2
Kaufman, R.J.3
-
3
-
-
1842843860
-
Coupling endoplasmic reticulum stress to the cell death program
-
Rao, R.V., Ellerby, H.M., and Bredesen, D.E. 2004. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ. 11:372-380.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 372-380
-
-
Rao, R.V.1
Ellerby, H.M.2
Bredesen, D.E.3
-
4
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge, D.G., Germain, M., Mathai, J.P., Nguyen, M., and Shore, G.G. 2003. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene. 22:8608-8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.G.5
-
5
-
-
0038464650
-
Regulation of cell death: The calcium-apoptosis link
-
Orrenius, S., Zhivotovsky, B., and Nicotera, P. 2003. Regulation of cell death: the calcium-apoptosis link [review]. Nat. Rev. Mol. Cell Biol. 4:552-565.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 552-565
-
-
Orrenius, S.1
Zhivotovsky, B.2
Nicotera, P.3
-
6
-
-
4444318357
-
ER chaperone functions during normal and stress conditions
-
Ma, Y., and Hendershot, L.M. 2004. ER chaperone functions during normal and stress conditions. J. Chem. Neuroanat. 28:51-65.
-
(2004)
J. Chem. Neuroanat.
, vol.28
, pp. 51-65
-
-
Ma, Y.1
Hendershot, L.M.2
-
7
-
-
1542350631
-
Flirting in little space: The ER/mitochondria Ca2+ liaison
-
Rizzuto, R., Duchen, M.R., and Pozzan, T. 2004. Flirting in little space: the ER/mitochondria Ca2+ liaison [review]. Sci STKE 2004:re1.
-
(2004)
Sci. STKE
, vol.2004
-
-
Rizzuto, R.1
Duchen, M.R.2
Pozzan, T.3
-
8
-
-
7744232493
-
Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
-
Rao, R.V., and Bredesen, D.E. 2004. Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. Curr. Opin. Cell Biol. 16:653-662.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 653-662
-
-
Rao, R.V.1
Bredesen, D.E.2
-
9
-
-
0031755020
-
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
-
Shi, Y., et al. 1998. Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol. Cell. Biol. 18:7499-7509.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7499-7509
-
-
Shi, Y.1
-
10
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum- resident kinase
-
Harding, H.P., Zhang, Y., and Ron, D. 1999. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature. 397:271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
11
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding, H.P., Zhang, Y., Bertolotti, A., Zeng, H., and Ron, D. 2000. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell. 5:897-904.
-
(2000)
Mol. Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
12
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
Scheuner, D., et al. 2001. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol. Cell. 7:1165-1176.
-
(2001)
Mol. Cell
, vol.7
, pp. 1165-1176
-
-
Scheuner, D.1
-
13
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida, H., Matsui, T., Yamamoto, A., Okada, T., and Mori, K. 2001. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. 107:881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
14
-
-
0037083755
-
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
-
Lee, K., et al. 2002. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev. 16:452-466.
-
(2002)
Genes Dev.
, vol.16
, pp. 452-466
-
-
Lee, K.1
-
15
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
Ye, J., et al. 2000. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol. Cell. 6:1355-1364.
-
(2000)
Mol. Cell
, vol.6
, pp. 1355-1364
-
-
Ye, J.1
-
16
-
-
1542380581
-
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB
-
Habelhah, H., et al. 2004. Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. EMBO J. 23:322-332.
-
(2004)
EMBO J.
, vol.23
, pp. 322-332
-
-
Habelhah, H.1
-
17
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano, F., et al. 2000. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science. 287:664-666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
-
18
-
-
0035957929
-
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
-
Yoneda, T., et al. 2001. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J. Biol. Chem. 276:13935-13940.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13935-13940
-
-
Yoneda, T.1
-
19
-
-
0030765016
-
Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells
-
Liu, H., et al. 1997. Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells. J. Biol. Chem. 272:21751-21759.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21751-21759
-
-
Liu, H.1
-
20
-
-
0034615941
-
Up-regulacion of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death
-
Tanaka, S., Uehara, T., and Nomura, Y. 2000. Up-regulacion of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death. J. Biol. Chem. 275:10388-10393.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10388-10393
-
-
Tanaka, S.1
Uehara, T.2
Nomura, Y.3
-
21
-
-
4444338911
-
Caspases involved in ER stress-mediated cell death
-
Momoi, T. 2004. Caspases involved in ER stress-mediated cell death. J. Chem. Neuroanat. 28:101-105.
-
(2004)
J. Chem. Neuroanat.
, vol.28
, pp. 101-105
-
-
Momoi, T.1
-
22
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
-
Nakagawa, T., et al. 2000. Caspase-12 mediates endoplasmic-reticulum- specific apoptosis and cytotoxicity by amyloid-β. Nature. 403:98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
-
23
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh, M., et al. 2004. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature. 429:75-79.
-
(2004)
Nature
, vol.429
, pp. 75-79
-
-
Saleh, M.1
-
24
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa, T., and Yuan, J. 2000. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell Biol. 150:887-894.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
25
-
-
0035823579
-
Coupling endoplasmic reticulum stress to the cell death program: Mechanism of caspase activation
-
Rao, R.V., et al. 2001. Coupling endoplasmic reticulum stress to the cell death program: mechanism of caspase activation. J. Biol. Chem. 276:33869-33874.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33869-33874
-
-
Rao, R.V.1
-
26
-
-
0036294646
-
Human caspase-12 has acquired deleterious mutations
-
Fischer, H., Koenig, U., Eckhart, L., and Tschachler, E. 2002. Human caspase-12 has acquired deleterious mutations. Biochem. Biophys. Res. Commun. 293:722-726.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 722-726
-
-
Fischer, H.1
Koenig, U.2
Eckhart, L.3
Tschachler, E.4
-
27
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
-
Hitomi, J., et al. 2004. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J. Cell Biol. 165:347-356.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
-
28
-
-
0030705234
-
L-and procaspase-8-associated protein in the endoplasmic reticulum
-
L-and procaspase-8-associated protein in the endoplasmic reticulum. J. Cell Biol. 139:327-338.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 327-338
-
-
Ng, F.W.H.1
-
29
-
-
0033816610
-
Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria
-
Nguyen, M., Breckenridge, D.G., Ducret, A., and Shore, G.G. 2000. Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria. Mol. Cell. Biol. 20:6731-6740.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6731-6740
-
-
Nguyen, M.1
Breckenridge, D.G.2
Ducret, A.3
Shore, G.G.4
-
30
-
-
0037417334
-
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
-
Breckenridge, D.G., Stojanovic, M., Marcellus, R., and Shore, G.G. 2003. Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J. Cell Biol. 160:1115-1127.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 1115-1127
-
-
Breckenridge, D.G.1
Stojanovic, M.2
Marcellus, R.3
Shore, G.G.4
-
31
-
-
0141893377
-
Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways
-
Roth, W., et al. 2003. Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways. Cell Death Differ. 10:1178-1187.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1178-1187
-
-
Roth, W.1
-
32
-
-
12944270500
-
BAR: An apoptosis regulator at the intersection of caspase and bcl-2 family proteins
-
Zhang, H., et al. 2000. BAR: an apoptosis regulator at the intersection of caspase and bcl-2 family proteins. Proc. Natl. Acad. Sci. U. S. A. 97:2597-2602.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 2597-2602
-
-
Zhang, H.1
-
33
-
-
0037040176
-
L expressing MCF7-Fas cells
-
L expressing MCF7-Fas cells. J. Biol. Chem. 277:4351-4360.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4351-4360
-
-
Stegh, A.H.1
-
34
-
-
0030986659
-
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
-
Kalchman, M.A., et al. 1997. HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain. Nat. Genet. 16:44-53.
-
(1997)
Nat. Genet.
, vol.16
, pp. 44-53
-
-
Kalchman, M.A.1
-
35
-
-
0036173770
-
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
-
Gervais, F.-G., et al. 2002. Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat. Cell Biol 4:95-105.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 95-105
-
-
Gervais, F.-G.1
-
36
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M.O. 2000. The biochemistry of apoptosis. Nature. 407:770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
37
-
-
9144253936
-
The ASK1-MAP kinase cascades in mammalian stress response
-
Matsukawa, J., Matsuzawa, A., Takeda, K., and Ichijo, H. 2004. The ASK1-MAP kinase cascades in mammalian stress response. J. Biochem. (Tokyo). 136:261-265.
-
(2004)
J. Biochem. (Tokyo)
, vol.136
, pp. 261-265
-
-
Matsukawa, J.1
Matsuzawa, A.2
Takeda, K.3
Ichijo, H.4
-
38
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh, H., et al. 2002. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 16:1345-1355.
-
(2002)
Genes Dev.
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
-
39
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependentapoptosis
-
Lei, K., and Davis, R.J. 2003. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependentapoptosis. Proc. Natl. Acad. Sci. U. S. A. 100:2432-2437.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
40
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
-
Putcha, G.V., et al. 2003. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron. 38:899-914.
-
(2003)
Neuron
, vol.38
, pp. 899-914
-
-
Putcha, G.V.1
-
41
-
-
0242521470
-
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its pro-apoptotic function
-
Luciano, F., et al. 2003. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its pro-apoptotic function. Oncogene. 22:6785-6793.
-
(2003)
Oncogene
, vol.22
, pp. 6785-6793
-
-
Luciano, F.1
-
42
-
-
0033499801
-
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M
-
Yamamoto, K., Ichijo, H., and Korsmeyer, S.J. 1999. BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol. Cell. Biol. 19:8469-8478.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8469-8478
-
-
Yamamoto, K.1
Ichijo, H.2
Korsmeyer, S.J.3
-
43
-
-
0035726625
-
Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis
-
Ito, Y., et al. 2001. Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis. Mol. Cell. Biol. 21:6233-6242.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6233-6242
-
-
Ito, Y.1
-
44
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari, S., and Mori, M. 2004. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11:381-389.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
45
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding, H.P., et al. 2003. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell. 11:619-633.
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
-
46
-
-
0029938805
-
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
-
Wang, X.Z., and Ron, D. 1996. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science. 272:1347-1349.
-
(1996)
Science
, vol.272
, pp. 1347-1349
-
-
Wang, X.Z.1
Ron, D.2
-
47
-
-
0033830234
-
Amino acids control mammalian gene transcription: Activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter
-
Bruhat, A., et al. 2000. Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter. Mol. Cell. Biol. 20:7192-7204.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7192-7204
-
-
Bruhat, A.1
-
48
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner, H., et al. 1998. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 12:982-995.
-
(1998)
Genes Dev.
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
-
49
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough, K.D., Martindale, J.L., Klotz, L.O., Aw, T.Y., and Holbrook, N.J. 2001. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol. Cell. Biol. 21:1249-1259.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
50
-
-
0035845568
-
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway
-
Oyadomari, S., et al. 2001. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc. Natl. Acad. Sci. U. S. A. 98:10845-10850.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 10845-10850
-
-
Oyadomari, S.1
-
51
-
-
0029928173
-
Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element
-
Ubeda, M., et al. 1996. Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Mol. Cell. Biol. 16:1479-1489.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1479-1489
-
-
Ubeda, M.1
-
52
-
-
0037157850
-
Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane
-
Bourdon, J.C., Renzing, J., Robertson, P.L., Fernandes, K.N., and Lane, D.P. 2002. Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane. J. Cell Biol. 158:235-246.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 235-246
-
-
Bourdon, J.C.1
Renzing, J.2
Robertson, P.L.3
Fernandes, K.N.4
Lane, D.P.5
-
53
-
-
0022546957
-
Analysis of the structute, transcripts, and protein products of Bcl-2, the gene involved in human follicular lymphoma
-
Tsujimoto, Y., and Croce, C. 1986. Analysis of the structute, transcripts, and protein products of Bcl-2, the gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci. U. S. A. 83:5214-5218.
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 5214-5218
-
-
Tsujimoto, Y.1
Croce, C.2
-
54
-
-
0344897663
-
Bcl-2 on the endoplasmic reticulum: Protecting the mitochondria from a distance
-
Thomenius, M.J., and Distelhorst, C.W. 2003. Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance [review]. J. Cell Sci. 116:4493-4499.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 4493-4499
-
-
Thomenius, M.J.1
Distelhorst, C.W.2
-
55
-
-
1942437456
-
Bim is a suppressor of Myc-induced mouse B cell leukemia
-
Egle, A., Harris, A.W., Bouillet, P., and Cory, S. 2004. Bim is a suppressor of Myc-induced mouse B cell leukemia. Proc. Natl. Acad. Sci. U. S. A. 101:6164-6169.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6164-6169
-
-
Egle, A.1
Harris, A.W.2
Bouillet, P.3
Cory, S.4
-
56
-
-
0037390872
-
Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum
-
Mund, T., Gewies, A., Schoenfeld, N., Bauer, M.K., and Grimm, S. 2003. Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum. FASEB J. 17:696-698,
-
(2003)
FASEB J.
, vol.17
, pp. 696-698
-
-
Mund, T.1
Gewies, A.2
Schoenfeld, N.3
Bauer, M.K.4
Grimm, S.5
-
57
-
-
0028965578
-
The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2
-
Yang, T., Kozopas, K.M., and Craig, R.W. 1995. The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2. J. Cell Biol. 128:1173-1184.
-
(1995)
J. Cell Biol.
, vol.128
, pp. 1173-1184
-
-
Yang, T.1
Kozopas, K.M.2
Craig, R.W.3
-
58
-
-
85047699843
-
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53
-
Mathai, J.P., Germain, M., Marcellus, R.C., and Shore, G.G. 2002. Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53. Oncogene. 21:2534-2544.
-
(2002)
Oncogene
, vol.21
, pp. 2534-2544
-
-
Mathai, J.P.1
Germain, M.2
Marcellus, R.C.3
Shore, G.G.4
-
59
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen, L., et al. 2005. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol. Cell. 17:393-403.
-
(2005)
Mol. Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
-
60
-
-
0042477717
-
Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
-
Reimertz, C., Kogel, D., Rami, A., Chittenden, T., and Prehn, J.H. 2003. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J. Cell Biol. 162:587-597.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 587-597
-
-
Reimertz, C.1
Kogel, D.2
Rami, A.3
Chittenden, T.4
Prehn, J.H.5
-
61
-
-
0031993255
-
BAX inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast
-
Xu, Q., and Reed, J.C. 1998. BAX inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol. Cell. 1:337-346.
-
(1998)
Mol. Cell
, vol.1
, pp. 337-346
-
-
Xu, Q.1
Reed, J.C.2
-
62
-
-
4344648874
-
Activating transcription factor 4 is translationally regulated by hypoxic stress
-
Blais, J.D., et al. 2004. Activating transcription factor 4 is translationally regulated by hypoxic stress. Mol. Cell. Biol. 24:7469-7482.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7469-7482
-
-
Blais, J.D.1
-
63
-
-
0345059069
-
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast
-
Chae, H.-J., et al. 2003. Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene. 323:101-113.
-
(2003)
Gene
, vol.323
, pp. 101-113
-
-
Chae, H.-J.1
-
64
-
-
4143087106
-
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
-
Chae, H.-J., et al. 2004. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol. Cell. 15:355-366.
-
(2004)
Mol. Cell
, vol.15
, pp. 355-366
-
-
Chae, H.-J.1
-
65
-
-
0036791634
-
Jafrac2 is an IAP antagonist that promotes cell death by liberating Drone from DIAP1
-
Tenev, T., Zachariou, A., Wilson, R., Paul, A., and Meier, P. 2002. Jafrac2 is an IAP antagonist that promotes cell death by liberating Drone from DIAP1. EMBO J. 21:5118-5129.
-
(2002)
EMBO J.
, vol.21
, pp. 5118-5129
-
-
Tenev, T.1
Zachariou, A.2
Wilson, R.3
Paul, A.4
Meier, P.5
-
66
-
-
0034304906
-
The versatility and universality of calcium signaling
-
Bertidge, M.J., Lipp, P., and Bootman, M.D. 2000. The versatility and universality of calcium signaling [review]. Nat. Rev. Mol. Cell Biol. 1:11-21.
-
(2000)
Nat. Rev. Mol. Cell Biol.
, vol.1
, pp. 11-21
-
-
Bertidge, M.J.1
Lipp, P.2
Bootman, M.D.3
-
67
-
-
4444372918
-
Ryanodine receptor channelopathies
-
Benkusky, N.A., Farrell, E.F., and Valdivia, H.H. 2004. Ryanodine receptor channelopathies. Biochem. Biophys. Res. Commun. 322:1280-1285.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 1280-1285
-
-
Benkusky, N.A.1
Farrell, E.F.2
Valdivia, H.H.3
-
68
-
-
0032827410
-
Mitochondrial transport of cations: Channels, exchangers, and permeability transition
-
Bernardi, P. 1999. Mitochondrial transport of cations: channels, exchangers, and permeability transition [review]. Physiol. Rev. 79:1127-1155.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1127-1155
-
-
Bernardi, P.1
-
69
-
-
0034068601
-
Mitochondrial control of cell death
-
Kroemer, G., and Reed, J.C. 2000. Mitochondrial control of cell death [review]. Nat. Med. 6:513-519.
-
(2000)
Nat. Med.
, vol.6
, pp. 513-519
-
-
Kroemer, G.1
Reed, J.C.2
-
70
-
-
0033213973
-
Caspase and calpain substtates: Roles in synaptic plasticity and cell death
-
Chan, S.L., and Mattson, M.P. 1999. Caspase and calpain substtates: roles in synaptic plasticity and cell death [review]. J. Neurosci. Res. 58:167-190.
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 167-190
-
-
Chan, S.L.1
Mattson, M.P.2
-
71
-
-
0034903587
-
The calpain family and human disease
-
Huang, Y., and Wang, K.K. 2001. The calpain family and human disease. Trends Mol. Med. 7:355-362.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 355-362
-
-
Huang, Y.1
Wang, K.K.2
-
72
-
-
0032480260
-
Bax cleavage is mediated by calpain during drug-induced apoptosis
-
Wood, D.E., et al. 1998. Bax cleavage is mediated by calpain during drug-induced apoptosis. Oncogene. 17:1069-1078.
-
(1998)
Oncogene
, vol.17
, pp. 1069-1078
-
-
Wood, D.E.1
-
73
-
-
0033583313
-
Caspase-dependent activation of calpain during drug-induced apoptosis
-
Wood, D.E., and Newcomb. E.W. 1999. Caspase-dependent activation of calpain during drug-induced apoptosis. J. Biol. Chem. 274:8309-8315.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8309-8315
-
-
Wood, D.E.1
Newcomb, E.W.2
-
74
-
-
0035903235
-
Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion
-
Chen, M., et al. 2001. Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion. J. Biol. Chem. 276:30724-30728.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30724-30728
-
-
Chen, M.1
-
76
-
-
0034306169
-
Cardiolipin provides specificity for targeting of tBid to mitochondria
-
Lutter, M., et al. 2000. Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat. Cell Biol. 2:754-756.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 754-756
-
-
Lutter, M.1
-
77
-
-
0036850312
-
Bid, bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana, T., et al. 2002. Bid, bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell. 111:331-342.
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
-
78
-
-
0033537768
-
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
Wang, H.G., et al. 1999. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science. 284:339-343.
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
-
79
-
-
0033595816
-
Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2
-
Youn, H., Sun, L., Prywes, R., and Liu, J. 1999. Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. Science. 286:790-793.
-
(1999)
Science
, vol.286
, pp. 790-793
-
-
Youn, H.1
Sun, L.2
Prywes, R.3
Liu, J.4
-
80
-
-
0037020686
-
The DAP-kinase family of proteins: Study of a novel group of calcium-regulated death-promoting kinases
-
Shohat, G., Shani, G., Eisenstein, M., and Kimchi, A. 2002. The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases [review]. Biochim. Biophys. Acta. 1600:45-50.
-
(2002)
Biochim. Biophys. Acta
, vol.1600
, pp. 45-50
-
-
Shohat, G.1
Shani, G.2
Eisenstein, M.3
Kimchi, A.4
-
81
-
-
4944222095
-
Drp-1-dependent division of the mitochondrial network blocks intra-organellar Ca2+ waves and protects against Ca2+-mediated apoptosis
-
Szabadkai, G., et al. 2004. Drp-1-dependent division of the mitochondrial network blocks intra-organellar Ca2+ waves and protects against Ca2+-mediated apoptosis. Mol. Cell. 16:59-68.
-
(2004)
Mol. Cell
, vol.16
, pp. 59-68
-
-
Szabadkai, G.1
-
82
-
-
16244384614
-
Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP
-
Liu, H., Peng, H.W., Cheng, Y.S., Yuan, H.S., and Yang-Yen, H.F. 2005. Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP. Mol Cell. Biol. 25:3117-3126.
-
(2005)
Mol Cell. Biol.
, vol.25
, pp. 3117-3126
-
-
Liu, H.1
Peng, H.W.2
Cheng, Y.S.3
Yuan, H.S.4
Yang-Yen, H.F.5
-
83
-
-
0031009968
-
Expression of bak in S. pombe results in a lethality mediated through interaction with the calnexin homologue Cnx1
-
Torgler, C.N., et al. 1997. Expression of bak in S. pombe results in a lethality mediated through interaction with the calnexin homologue Cnx1. Cell Death Differ. 4:263-271.
-
(1997)
Cell Death Differ.
, vol.4
, pp. 263-271
-
-
Torgler, C.N.1
-
84
-
-
0027523461
-
Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production
-
Baffy, G., Miyashita, T., Williamson, J.R., and Reed, J.C. 1993. Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J. Biol. Chem. 268:6511-6519.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6511-6519
-
-
Baffy, G.1
Miyashita, T.2
Williamson, J.R.3
Reed, J.C.4
-
85
-
-
0030824575
-
Maintenance of calcium homeostasis in the reticulum by Bcl-2
-
He, H., Lam, M., McCormick, T.S., and Distelhorst, C.W. 1997. Maintenance of calcium homeostasis in the reticulum by Bcl-2. J. Cell Biol. 138:1219-1228.
-
(1997)
J. Cell Biol.
, vol.138
, pp. 1219-1228
-
-
He, H.1
Lam, M.2
McCormick, T.S.3
Distelhorst, C.W.4
-
86
-
-
0034610995
-
Reduced loading of intracellular Ca2+ stores and downregulation of capacitative Ca2+ influx in Bcl-2-overexpressing cells
-
Pinton, P., et al. 2000. Reduced loading of intracellular Ca2+ stores and downregulation of capacitative Ca2+ influx in Bcl-2-overexpressing cells. J. Cell Biol. 148:857-862.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 857-862
-
-
Pinton, P.1
-
87
-
-
0035355341
-
2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: Significance for the molecular mechanism of Bcl-2 action
-
2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J. 20:2690-2701.
-
(2001)
EMBO J.
, vol.20
, pp. 2690-2701
-
-
Pinton, P.1
-
88
-
-
0037418861
-
Cell biology: Apoptosis. The calcium connection
-
Demaurex, N., and Distelhorst, C. 2003. Cell biology: apoptosis. The calcium connection. Science. 300:65-67.
-
(2003)
Science
, vol.300
, pp. 65-67
-
-
Demaurex, N.1
Distelhorst, C.2
-
89
-
-
0037418843
-
BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis
-
Scorrano, L., et al. 2003. BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. Science. 300:135-139.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
-
90
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei, M.C., et al. 2001. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science. 292:727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
-
91
-
-
0034698838
-
Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis
-
Nakamura, K., et al. 2000. Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis. J. Cell Biol. 150:731-740.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 731-740
-
-
Nakamura, K.1
-
92
-
-
10644234677
-
Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor
-
Palmer, A.E. Jin, C., Reed, J.C., and Tsien, R.Y. 2004. Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc. Natl. Acad. Sci. U. S. A. 101:17404-17409.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 17404-17409
-
-
Palmer, A.E.1
Jin, C.2
Reed, J.C.3
Tsien, R.Y.4
-
93
-
-
0031823480
-
Bcl-2 family proteins as ion-channels
-
Schendel, S., Montai, M., and Reed, J.C. 1998. Bcl-2 family proteins as ion-channels. Cell Death Differ. 5:372-380.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 372-380
-
-
Schendel, S.1
Montai, M.2
Reed, J.C.3
-
94
-
-
11144243134
-
Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region
-
Chami, M., et al. 2004. Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region. J. Biol. Chem. 279:54581-54589.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54581-54589
-
-
Chami, M.1
-
95
-
-
0032532213
-
Modulation of endoplasmic reticulum calcium pump by Bcl-2
-
Kuo, T.H., et al. 1998. Modulation of endoplasmic reticulum calcium pump by Bcl-2. Oncogene. 17:1903-1910.
-
(1998)
Oncogene
, vol.17
, pp. 1903-1910
-
-
Kuo, T.H.1
-
96
-
-
11844284861
-
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
-
Oakes, S.A., et al. 2005. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc. Natl. Acad. Sci. U. S. A. 102:105-110.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 105-110
-
-
Oakes, S.A.1
-
97
-
-
0344825875
-
Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis
-
Boehning, D., et al. 2003. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat. Cell Biol. 5:1051-1061.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 1051-1061
-
-
Boehning, D.1
-
98
-
-
0030973158
-
T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis
-
Jayaraman, T., and Marks, A.R. 1997. T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis. Mol. Cell. Biol. 17:3005-3012.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3005-3012
-
-
Jayaraman, T.1
Marks, A.R.2
-
99
-
-
0029824312
-
Lymphocyte apoptosis: Mediation by increased type 3 inositol 1,4,5-trisphosphate receptor
-
Khan, A.A., et al. 1996. Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science. 273:503-507.
-
(1996)
Science
, vol.273
, pp. 503-507
-
-
Khan, A.A.1
-
100
-
-
0033945128
-
Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death
-
Blackshaw, S., et al. 2000. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. FASEB J. 14:1375-1379.
-
(2000)
FASEB J.
, vol.14
, pp. 1375-1379
-
-
Blackshaw, S.1
-
101
-
-
0013148718
-
Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria
-
Wang, B., et al. 2003. Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria. J. Biol. Chem. 278:14461-14468.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14461-14468
-
-
Wang, B.1
-
102
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama, T., et al. 1999. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat. Cell Biol. 1:479-485.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 479-485
-
-
Katayama, T.1
-
103
-
-
0037102939
-
Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress
-
Terro, F., et al. 2002. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress. J. Neurosci. Res. 69:530-539.
-
(2002)
J. Neurosci. Res.
, vol.69
, pp. 530-539
-
-
Terro, F.1
-
104
-
-
0036828371
-
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations
-
Milhavet, O., et al. 2002. Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations. J. Neurochem. 83:673-681.
-
(2002)
J. Neurochem.
, vol.83
, pp. 673-681
-
-
Milhavet, O.1
-
105
-
-
0033598996
-
A role for presenilin-1 in nuclear accumulation of ire1 fragments and induction of the mammalian unfolded protein response
-
Niwa, M., Sidrauski, C., Kaufman, R., and Walter, P. 1999. A role for presenilin-1 in nuclear accumulation of ire1 fragments and induction of the mammalian unfolded protein response. Cell. 99:691-702.
-
(1999)
Cell
, vol.99
, pp. 691-702
-
-
Niwa, M.1
Sidrauski, C.2
Kaufman, R.3
Walter, P.4
-
106
-
-
0037240325
-
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
-
doi:10.1172/JCI200317575
-
Dawson, T.M., and Dawson, V.L. 2003. Rare genetic mutations shed light on the pathogenesis of Parkinson disease. J. Clin. Invest. 111:145-151. doi:10.1172/JCI200317575.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 145-151
-
-
Dawson, T.M.1
Dawson, V.L.2
-
107
-
-
0038389675
-
Parkin and endoplasmic reticulum stress
-
Takahashi, R., Imai, Y., Hattori, N., and Mizuno, Y. 2003. Parkin and endoplasmic reticulum stress, Ann. N. Y. Acad. Sci. 991:101-106.
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.991
, pp. 101-106
-
-
Takahashi, R.1
Imai, Y.2
Hattori, N.3
Mizuno, Y.4
-
108
-
-
0031761706
-
Protein precipitation: A common etiology in neurodegenerative disorders?
-
Kakizuka, A. 1998. Protein precipitation: a common etiology in neurodegenerative disorders? Trends Genet. 14:396-402.
-
(1998)
Trends Genet.
, vol.14
, pp. 396-402
-
-
Kakizuka, A.1
-
109
-
-
0037096823
-
Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation
-
Kouroku, Y., et al. 2002. Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation. Hum. Mol. Genet. 11:1505-1515.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1505-1515
-
-
Kouroku, Y.1
-
110
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence, N.F., Sampat, R.M., and Kopito, R.R. 2001. Impairment of the ubiquitin-proteasome system by protein aggregation. Science. 292:1552-1555.
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
111
-
-
0034996080
-
Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK
-
Kumar, R., et al. 2001. Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK. J. Neurochem. 77:1418-1421.
-
(2001)
J. Neurochem.
, vol.77
, pp. 1418-1421
-
-
Kumar, R.1
-
112
-
-
0032544514
-
Activation of gadd153 expression through transient cerebral ischemia: Evidence that ischemia causes endoplasmic reticulum dysfunction
-
Paschen, W., Gissel, C., Linden, T., Althausen, S., and Doutheil, J. 1998. Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction. Brain Res. Mol. Brain Res. 60:115-122.
-
(1998)
Brain Res. Mol. Brain Res.
, vol.60
, pp. 115-122
-
-
Paschen, W.1
Gissel, C.2
Linden, T.3
Althausen, S.4
Doutheil, J.5
-
113
-
-
1842854719
-
Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress path way involving CHOP
-
Tajiri, S., et al. 2004. Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress path way involving CHOP. Cell Death Differ. 11:403-415.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 403-415
-
-
Tajiri, S.1
-
114
-
-
0031048249
-
Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil
-
Kohno, K., Higuchi, T., Ohta, S., Kumon, Y., and Sakaki, S. 1997. Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil. Neurosci. Lett. 224:17-20.
-
(1997)
Neurosci. Lett.
, vol.224
, pp. 17-20
-
-
Kohno, K.1
Higuchi, T.2
Ohta, S.3
Kumon, Y.4
Sakaki, S.5
-
115
-
-
0030664096
-
Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene
-
Iadecola, C., Zhang, F., Casey, R., Nagayama, M., and Ross, M.E. 1997. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J. Neurosci. 17:9157-9164.
-
(1997)
J. Neurosci.
, vol.17
, pp. 9157-9164
-
-
Iadecola, C.1
Zhang, F.2
Casey, R.3
Nagayama, M.4
Ross, M.E.5
-
116
-
-
9144231898
-
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling
-
Yamaguchi, O., et al. 2003. Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc. Natl. Acad. Sci. U. S. A. 100:15883-15888.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 15883-15888
-
-
Yamaguchi, O.1
-
117
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival
-
Harding, H.P., et al. 2001. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol. Cell. 7:1153-1163.
-
(2001)
Mol. Cell
, vol.7
, pp. 1153-1163
-
-
Harding, H.P.1
-
118
-
-
0037288692
-
Endoplasmic reticulum stress and diabetes mellitus
-
Araki, E., Oyadomari, S., and Mori, M. 2003. Endoplasmic reticulum stress and diabetes mellitus. Intern. Med. 42:7-14.
-
(2003)
Intern. Med.
, vol.42
, pp. 7-14
-
-
Araki, E.1
Oyadomari, S.2
Mori, M.3
-
119
-
-
0036175128
-
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
-
doi:10.1172/JCI200214550
-
Oyadomari, S., et al. 2002. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J. Clin. Invest. 109:525-532. doi:10.1172/JCI200214550.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 525-532
-
-
Oyadomari, S.1
-
120
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan, U., et al. 2004. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 306:457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
-
121
-
-
14944371187
-
The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis
-
doi:10.1172/JCI200521848
-
Zhang, K., et al. 2005. The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis. J. Clin. Invest. 115:268-281. doi:10.1172/JCI200521848.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 268-281
-
-
Zhang, K.1
-
122
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce, M., et al. 2005. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science. 307:935-939,
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
-
123
-
-
0034641936
-
Apoptosis in the nervous system
-
Yuan, J., and Yankner, B.A. 2000. Apoptosis in the nervous system. Nature. 407:802-809.
-
(2000)
Nature
, vol.407
, pp. 802-809
-
-
Yuan, J.1
Yankner, B.A.2
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