Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin-proteasome system in human sarcoma cells

Cancer Letters

Volumn 356, Issue 2, 2015, Pages 762-772

  Chiu, Hui Wen ^a,b,c   Tseng, Yin Chiu ^a   Hsu, Yung Ho ^b   Lin, Yuh Feng ^b,c   Foo, Ning Ping ^a,d,e   Guo, How Ran ^a,f   Wang, Ying Jan ^a,g,h  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHI MEI MEDICAL CENTER   (Taiwan)

^e Tainan Municipal An Nan Hospital China Medical University   (Taiwan)

^f NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^g ASIA UNIVERSITY   (Taiwan)

^h CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Arsenic trioxide; Autophagy; Endoplasmic reticulum stress; Sarcoma; Ubiquitin proteasome system

Indexed keywords

ARSENIC TRIOXIDE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEASOME; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UBIQUITIN; ANTINEOPLASTIC AGENT; ORGANOARSENIC DERIVATIVE; OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL MEDIATED CYTOTOXICITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROSARCOMA; FIBROSARCOMA CELL LINE; HOS CELL LINE; HT1080 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL LINE; SIGNAL TRANSDUCTION; ANIMAL; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; SARCOMA; SCID MOUSE; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENICALS; AUTOPHAGY; BLOTTING, WESTERN; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; HUMANS; MALE; MICE; MICE, INBRED NOD; MICE, SCID; OXIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; SARCOMA; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UBIQUITIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84919483390     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.10.025     Document Type: Article

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