메뉴 건너뛰기




Volumn 295, Issue 2, 2008, Pages

Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces

Author keywords

Apoptosis; Homeostasis

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC G 418; CALCINEURIN INHIBITOR; CISPLATIN; CYCLOSPORIN A; CYSTEINE CONJUGATE; GENTAMICIN; INDOMETACIN; INITIATION FACTOR 2ALPHA; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PODOCIN; PROTEIN IRE1; TACROLIMUS; X BOX BINDING PROTEIN 1;

EID: 52449128023     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00050.2008     Document Type: Review
Times cited : (161)

References (137)
  • 1
    • 0036328117 scopus 로고    scopus 로고
    • Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress
    • Abcouwer SF, Marjon PL, Loper RK, Vander Jagt DL. Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress. Invest Ophthalmol Vis Sci 43: 2791-2798, 2002.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 2791-2798
    • Abcouwer, S.F.1    Marjon, P.L.2    Loper, R.K.3    Vander Jagt, D.L.4
  • 3
    • 27944432606 scopus 로고    scopus 로고
    • Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo
    • Asmellash S, Stevens JL, Ichimura T. Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo. Toxicol Sci 88: 576-584, 2005.
    • (2005) Toxicol Sci , vol.88 , pp. 576-584
    • Asmellash, S.1    Stevens, J.L.2    Ichimura, T.3
  • 5
    • 39349083349 scopus 로고    scopus 로고
    • A highly sensitive assay for monitoring the secretory pathway and ER stress
    • Badr CE, Hewett JW, Breakefield XO, Tannous BA. A highly sensitive assay for monitoring the secretory pathway and ER stress. PLoS ONE 2: e571, 2007.
    • (2007) PLoS ONE , vol.2
    • Badr, C.E.1    Hewett, J.W.2    Breakefield, X.O.3    Tannous, B.A.4
  • 8
    • 0033984036 scopus 로고    scopus 로고
    • Modulation of endoplasmic reticulum-bound cholesterol regulatory enzymes by iron/ascorbate-mediated lipid peroxidation
    • Brunet S, Thibault L, Lepage G, Seidman EG, Dubé N, Levy E. Modulation of endoplasmic reticulum-bound cholesterol regulatory enzymes by iron/ascorbate-mediated lipid peroxidation. Free Radic Biol Med 28: 46-54, 2000.
    • (2000) Free Radic Biol Med , vol.28 , pp. 46-54
    • Brunet, S.1    Thibault, L.2    Lepage, G.3    Seidman, E.G.4    Dubé, N.5    Levy, E.6
  • 9
    • 4444237848 scopus 로고    scopus 로고
    • Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology
    • Conn KJ, Gao W, McKee A, Lan MS, Ullman MD, Eisenhauer PB, Fine RE, Wells JM. Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology. Brain Res 1022: 164-172, 2004.
    • (2004) Brain Res , vol.1022 , pp. 164-172
    • Conn, K.J.1    Gao, W.2    McKee, A.3    Lan, M.S.4    Ullman, M.D.5    Eisenhauer, P.B.6    Fine, R.E.7    Wells, J.M.8
  • 10
    • 21644458029 scopus 로고    scopus 로고
    • Role of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injury
    • Cybulsky AV, Takano T, Papillon J, Bijian K. Role of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injury. J Biol Chem 280: 24396-24403, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 24396-24403
    • Cybulsky, A.V.1    Takano, T.2    Papillon, J.3    Bijian, K.4
  • 11
    • 0036828990 scopus 로고    scopus 로고
    • Complement C5b-9 membrane attack complex increases expression of endoplasmic reticulum stress proteins in glomerular epithelial cells
    • Cybulsky AV, Takano T, Papillon J, Khadir A, Liu J, Peng H. Complement C5b-9 membrane attack complex increases expression of endoplasmic reticulum stress proteins in glomerular epithelial cells. J Biol Chem 277: 41342-41351, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 41342-41351
    • Cybulsky, A.V.1    Takano, T.2    Papillon, J.3    Khadir, A.4    Liu, J.5    Peng, H.6
  • 12
    • 0034425698 scopus 로고    scopus 로고
    • EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome
    • Delepine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C. EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 25: 406-409, 2000.
    • (2000) Nat Genet , vol.25 , pp. 406-409
    • Delepine, M.1    Nicolino, M.2    Barrett, T.3    Golamaully, M.4    Lathrop, G.M.5    Julier, C.6
  • 13
    • 8644282751 scopus 로고    scopus 로고
    • Translational repression mediates activation of nuclear factor-κB by phosphorylated translation initiation factor 2
    • Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, Harding HP, Ron D. Translational repression mediates activation of nuclear factor-κB by phosphorylated translation initiation factor 2. Mol Cell Biol 24: 10161-10168, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 10161-10168
    • Deng, J.1    Lu, P.D.2    Zhang, Y.3    Scheuner, D.4    Kaufman, R.J.5    Sonenberg, N.6    Harding, H.P.7    Ron, D.8
  • 14
    • 0035021123 scopus 로고    scopus 로고
    • The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
    • Devin A, Lin Y, Yamaoka S, Li Z, Karin M, Liu Z. The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol Cell Biol 21: 3986-3994, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 3986-3994
    • Devin, A.1    Lin, Y.2    Yamaoka, S.3    Li, Z.4    Karin, M.5    Liu, Z.6
  • 15
    • 33644790277 scopus 로고    scopus 로고
    • Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: Implications in atherogenesis
    • Dickhout JG, Hossain GS, Pozza LM, Zhou J, Lhotak S, Austin RC. Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler Thromb Vasc Biol 25: 2623-2629, 2005.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2623-2629
    • Dickhout, J.G.1    Hossain, G.S.2    Pozza, L.M.3    Zhou, J.4    Lhotak, S.5    Austin, R.C.6
  • 17
    • 28844470269 scopus 로고    scopus 로고
    • The unfolded protein response: A novel component of the hypoxic stress response in tumors
    • Feldman DE, Chauhan V, Koong AC. The unfolded protein response: a novel component of the hypoxic stress response in tumors. Mol Cancer Res 3: 597-605, 2005.
    • (2005) Mol Cancer Res , vol.3 , pp. 597-605
    • Feldman, D.E.1    Chauhan, V.2    Koong, A.C.3
  • 18
  • 20
    • 0037292110 scopus 로고    scopus 로고
    • Prieto P. Sensitive endpoints for evaluating cadmium-induced acute toxicity in LLC-PK1 cells
    • Gennari A, Cortese E, Boveri M, Casado J, Prieto P. Sensitive endpoints for evaluating cadmium-induced acute toxicity in LLC-PK1 cells. Toxicology 183: 211-220, 2003.
    • (2003) Toxicology , vol.183 , pp. 211-220
    • Gennari, A.1    Cortese, E.2    Boveri, M.3    Casado, J.4
  • 21
    • 33745962325 scopus 로고    scopus 로고
    • Nitric oxide and endoplasmic reticulum stress
    • Gotoh T, Mori M. Nitric oxide and endoplasmic reticulum stress. Arterioscler Thromb Vasc Biol 26: 1439-1446, 2006.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1439-1446
    • Gotoh, T.1    Mori, M.2
  • 22
    • 0037023726 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
    • Gotoh T, Oyadomari S, Mori K, Mori M. Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP. J Biol Chem 277: 12343-12350, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 12343-12350
    • Gotoh, T.1    Oyadomari, S.2    Mori, K.3    Mori, M.4
  • 23
    • 0034968330 scopus 로고    scopus 로고
    • Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival
    • Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell 7: 1153-1163, 2001.
    • (2001) Mol Cell , vol.7 , pp. 1153-1163
    • Harding, H.P.1    Zeng, H.2    Zhang, Y.3    Jungries, R.4    Chung, P.5    Plesken, H.6    Sabatini, D.D.7    Ron, D.8
  • 24
    • 60549085835 scopus 로고    scopus 로고
    • Acquisition of anergy to proinflammatory cytokines in nonimmune cells through endoplasmic reticulum stress response: A mechanism for subsidence of inflammation
    • In press
    • Hayakawa K, Hiramatsu N, Okamura M, Yamazaki H, Yao J, Paton AW, Paton JC, Kitamura M. Acquisition of anergy to proinflammatory cytokines in nonimmune cells through endoplasmic reticulum stress response: a mechanism for subsidence of inflammation. J Immunol. In press.
    • J Immunol
    • Hayakawa, K.1    Hiramatsu, N.2    Okamura, M.3    Yamazaki, H.4    Yao, J.5    Paton, A.W.6    Paton, J.C.7    Kitamura, M.8
  • 25
    • 36048993417 scopus 로고    scopus 로고
    • Blunted activation of NF-κB and NF-κB-dependent gene expression by geranylgeranylacetone: Involvement of unfolded protein response
    • Hayakawa K, Hiramatsu N, Okamura M, Yao J, Paton AW, Paton JC, Kitamura M. Blunted activation of NF-κB and NF-κB-dependent gene expression by geranylgeranylacetone: involvement of unfolded protein response. Biochem Biophys Res Commun 365: 47-53, 2008.
    • (2008) Biochem Biophys Res Commun , vol.365 , pp. 47-53
    • Hayakawa, K.1    Hiramatsu, N.2    Okamura, M.3    Yao, J.4    Paton, A.W.5    Paton, J.C.6    Kitamura, M.7
  • 26
    • 11844282198 scopus 로고    scopus 로고
    • Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons
    • Hayashi T, Saito A, Okuno S, Ferrand-Drake M, Dodd RL, Chan PH. Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons. J Cereb Blood Flow Metab 25: 41-53, 2005.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 41-53
    • Hayashi, T.1    Saito, A.2    Okuno, S.3    Ferrand-Drake, M.4    Dodd, R.L.5    Chan, P.H.6
  • 27
    • 0034735905 scopus 로고    scopus 로고
    • Involvement of c-Fos in signaling grp78 induction following ER calcium release
    • He H, McColl K, Distelhorst CW. Involvement of c-Fos in signaling grp78 induction following ER calcium release. Oncogene 19: 5936-5943, 2000.
    • (2000) Oncogene , vol.19 , pp. 5936-5943
    • He, H.1    McColl, K.2    Distelhorst, C.W.3
  • 29
    • 34247625576 scopus 로고    scopus 로고
    • Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice
    • Hiramatsu N, Kasai A, Du S, Takeda M, Hayakawa K, Okamura M, Yao J, Kitamura M. Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: evidence from transgenic sensor mice. FEBS Lett 581: 2055-2059, 2007.
    • (2007) FEBS Lett , vol.581 , pp. 2055-2059
    • Hiramatsu, N.1    Kasai, A.2    Du, S.3    Takeda, M.4    Hayakawa, K.5    Okamura, M.6    Yao, J.7    Kitamura, M.8
  • 30
    • 33746838912 scopus 로고    scopus 로고
    • Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP: Evidence for systemic, transient ER stress during endotoxemia
    • Hiramatsu N, Kasai A, Hayakawa K, Yao J, Kitamura M. Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP: evidence for systemic, transient ER stress during endotoxemia. Nucleic Acids Res 34: e93, 2006.
    • (2006) Nucleic Acids Res , vol.34
    • Hiramatsu, N.1    Kasai, A.2    Hayakawa, K.3    Yao, J.4    Kitamura, M.5
  • 31
    • 15444369420 scopus 로고    scopus 로고
    • Alkaline phosphatase vs. luciferase as secreted reporter molecules in vivo
    • Hiramatsu N, Kasai A, Meng Y, Hayakawa K, Yao J, Kitamura M. Alkaline phosphatase vs. luciferase as secreted reporter molecules in vivo. Anal Biochem 339: 249-256, 2005.
    • (2005) Anal Biochem , vol.339 , pp. 249-256
    • Hiramatsu, N.1    Kasai, A.2    Meng, Y.3    Hayakawa, K.4    Yao, J.5    Kitamura, M.6
  • 32
    • 0038143287 scopus 로고    scopus 로고
    • Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
    • Holtz WA, O'Malley KL. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J Biol Chem 278: 19367-19377, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 19367-19377
    • Holtz, W.A.1    O'Malley, K.L.2
  • 34
    • 33645815074 scopus 로고    scopus 로고
    • Autocrine tumor necrosis factor-α links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and downregulation of TRAF2 expression
    • Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. Autocrine tumor necrosis factor-α links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and downregulation of TRAF2 expression. Mol Cell Biol 26: 3071-3084, 2006.
    • (2006) Mol Cell Biol , vol.26 , pp. 3071-3084
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Kaufman, R.J.4    Exton, J.H.5
  • 35
    • 0041853778 scopus 로고    scopus 로고
    • Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation
    • Hung CC, Ichimura T, Stevens JL, Bonventre JV. Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem 278: 29317-29326, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 29317-29326
    • Hung, C.C.1    Ichimura, T.2    Stevens, J.L.3    Bonventre, J.V.4
  • 36
    • 57049096489 scopus 로고    scopus 로고
    • IPCS. Cadmium. Environmental Health Criteria 134, World Health Organization, Geneva, 1992.
    • IPCS. Cadmium. Environmental Health Criteria 134, World Health Organization, Geneva, 1992.
  • 37
    • 0037385313 scopus 로고    scopus 로고
    • Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP1
    • Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP1. Nat Immun 4: 321-329, 2003.
    • (2003) Nat Immun , vol.4 , pp. 321-329
    • Iwakoshi, N.N.1    Lee, A.H.2    Vallabhajosyula, P.3    Otipoby, K.L.4    Rajewsky, K.5    Glimcher, L.H.6
  • 38
    • 1842612402 scopus 로고    scopus 로고
    • A transgenic mouse model for monitoring endoplasmic reticulum stress
    • Iwawaki T, Akai R, Kohno K, Miura M. A transgenic mouse model for monitoring endoplasmic reticulum stress. Nat Med 10: 98-102, 2004.
    • (2004) Nat Med , vol.10 , pp. 98-102
    • Iwawaki, T.1    Akai, R.2    Kohno, K.3    Miura, M.4
  • 39
    • 0033858895 scopus 로고    scopus 로고
    • Cadmium decreases gap junctional intercellular communication in mouse liver
    • Jeong SH, Habeebu SS, Klaassen CD. Cadmium decreases gap junctional intercellular communication in mouse liver. Toxicol Sci 57: 156-166, 2000.
    • (2000) Toxicol Sci , vol.57 , pp. 156-166
    • Jeong, S.H.1    Habeebu, S.S.2    Klaassen, C.D.3
  • 40
    • 0043133837 scopus 로고    scopus 로고
    • Phosphorylation of the α subunit of eukaryotic initiation factor 2 is required for activation of NF-κB in response to diverse cellular stresses
    • Jiang HY, Wek SA, McGrath BC, Scheuner D, Kaufman RJ, Cavener DR, Wek RC. Phosphorylation of the α subunit of eukaryotic initiation factor 2 is required for activation of NF-κB in response to diverse cellular stresses. Mol Cell Biol 23: 5651-5663, 2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 5651-5663
    • Jiang, H.Y.1    Wek, S.A.2    McGrath, B.C.3    Scheuner, D.4    Kaufman, R.J.5    Cavener, D.R.6    Wek, R.C.7
  • 41
    • 3843127562 scopus 로고    scopus 로고
    • Cytochrome c release and endoplasmic reticulum stress are involved in caspase-dependent apoptosis induced by G418
    • Jin QH, Zhao B, Zhang XJ. Cytochrome c release and endoplasmic reticulum stress are involved in caspase-dependent apoptosis induced by G418. Cell Mol Life Sci 61: 1816-1825, 2004.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 1816-1825
    • Jin, Q.H.1    Zhao, B.2    Zhang, X.J.3
  • 42
    • 0344236406 scopus 로고    scopus 로고
    • Intracellular mechanisms of cyclosporin A-induced tubular cell apoptosis
    • Justo P, Lorz C, Sanz A, Egido J, Ortiz A. Intracellular mechanisms of cyclosporin A-induced tubular cell apoptosis. J Am Soc Nephrol 14: 3072-3080, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3072-3080
    • Justo, P.1    Lorz, C.2    Sanz, A.3    Egido, J.4    Ortiz, A.5
  • 45
    • 0027997238 scopus 로고
    • Antibiotic-related nephrotoxicity
    • Kaloyanides GJ. Antibiotic-related nephrotoxicity. Nephrol Dial Transplant 9, Suppl 4: 130-134, 1994.
    • (1994) Nephrol Dial Transplant , vol.9 , Issue.SUPPL. 4 , pp. 130-134
    • Kaloyanides, G.J.1
  • 46
    • 1442321303 scopus 로고    scopus 로고
    • Activation signal of nuclear factor-κB in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2
    • Kaneko M, Niinuma Y, Nomura Y. Activation signal of nuclear factor-κB in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2. Biol Pharm Bull 26: 931-935, 2003.
    • (2003) Biol Pharm Bull , vol.26 , pp. 931-935
    • Kaneko, M.1    Niinuma, Y.2    Nomura, Y.3
  • 48
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman RJ. Orchestrating the unfolded protein response in health and disease. J Clin Invest 110: 1389-1398, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 50
    • 31444449462 scopus 로고    scopus 로고
    • Role of the unfolded protein response in cell death
    • Kim R, Emi M, Tanabe K, Murakami S. Role of the unfolded protein response in cell death. Apoptosis 11: 5-13, 2006.
    • (2006) Apoptosis , vol.11 , pp. 5-13
    • Kim, R.1    Emi, M.2    Tanabe, K.3    Murakami, S.4
  • 51
    • 37549033821 scopus 로고    scopus 로고
    • Dysfunction of the ER chaperone BiP accelerates the renal tubular injury
    • Kimura K, Jin H, Ogawa M, Aoe T. Dysfunction of the ER chaperone BiP accelerates the renal tubular injury. Biochem Biophys Res Commun 366: 1048-1053, 2008.
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 1048-1053
    • Kimura, K.1    Jin, H.2    Ogawa, M.3    Aoe, T.4
  • 52
    • 0023852783 scopus 로고
    • The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
    • Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 332: 462-464, 1988.
    • (1988) Nature , vol.332 , pp. 462-464
    • Kozutsumi, Y.1    Segal, M.2    Normington, K.3    Gething, M.J.4    Sambrook, J.5
  • 53
    • 0026699666 scopus 로고
    • Transcriptional activation of the tumor necrosis factor α-inducible zinc finger protein, A20, is mediated by κB elements
    • Krikos A, Laherty CD, Dixit VM. Transcriptional activation of the tumor necrosis factor α-inducible zinc finger protein, A20, is mediated by κB elements. J Biol Chem 267: 17971-17976, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 17971-17976
    • Krikos, A.1    Laherty, C.D.2    Dixit, V.M.3
  • 54
    • 0037409307 scopus 로고    scopus 로고
    • Geldanamycin induction of grp78 requires activation of reactive oxygen species via ER stress responsive elements in 9L rat brain tumour cells
    • Lai MT, Huang KL, Chang WM, Lai YK. Geldanamycin induction of grp78 requires activation of reactive oxygen species via ER stress responsive elements in 9L rat brain tumour cells. Cell Signal 15: 585-595, 2003.
    • (2003) Cell Signal , vol.15 , pp. 585-595
    • Lai, M.T.1    Huang, K.L.2    Chang, W.M.3    Lai, Y.K.4
  • 55
    • 0242610852 scopus 로고    scopus 로고
    • Glucose depletion enhances P-glycoprotein expression in hepatoma cells: Role of endoplasmic reticulum stress response
    • Ledoux S, Yang R, Friedlander G, Laouari D. Glucose depletion enhances P-glycoprotein expression in hepatoma cells: role of endoplasmic reticulum stress response. Cancer Res 63: 7284-7290, 2003.
    • (2003) Cancer Res , vol.63 , pp. 7284-7290
    • Ledoux, S.1    Yang, R.2    Friedlander, G.3    Laouari, D.4
  • 56
    • 0035423875 scopus 로고    scopus 로고
    • The glucose-regulated proteins: Stress induction and clinical applications
    • Lee AS. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci 26: 504-510, 2001.
    • (2001) Trends Biochem Sci , vol.26 , pp. 504-510
    • Lee, A.S.1
  • 58
    • 33745022822 scopus 로고    scopus 로고
    • Cadmium induces the expression of Grp78, an endoplasmic reticulum molecular chaperone, in LLC-PK1 renal epithelial cells
    • Liu F, Inageda K, Nishitai G, Matsuoka M. Cadmium induces the expression of Grp78, an endoplasmic reticulum molecular chaperone, in LLC-PK1 renal epithelial cells. Environ Health Perspect 114: 859-864, 2006.
    • (2006) Environ Health Perspect , vol.114 , pp. 859-864
    • Liu, F.1    Inageda, K.2    Nishitai, G.3    Matsuoka, M.4
  • 59
    • 27744500069 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-associated caspase-12 mediates cisplatin-induced LLC-PK1 cell apoptosis
    • Liu H, Baliga R. Endoplasmic reticulum stress-associated caspase-12 mediates cisplatin-induced LLC-PK1 cell apoptosis. J Am Soc Nephrol 16: 1985-1992, 2005.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1985-1992
    • Liu, H.1    Baliga, R.2
  • 60
    • 0035510132 scopus 로고    scopus 로고
    • Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: Insight into the mechanisms of congenital nephrotic syndrome
    • Liu L, Done SC, Khoshnoodi J, Bertorello A, Wartiovaara J, Berggren PO, Tryggvason K. Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: insight into the mechanisms of congenital nephrotic syndrome. Hum Mol Genet 10: 2637-2644, 2001.
    • (2001) Hum Mol Genet , vol.10 , pp. 2637-2644
    • Liu, L.1    Done, S.C.2    Khoshnoodi, J.3    Bertorello, A.4    Wartiovaara, J.5    Berggren, P.O.6    Tryggvason, K.7
  • 64
    • 0036314984 scopus 로고    scopus 로고
    • Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
    • Ma Y, Brewer JW, Diehl JA, Hendershot LM. Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J Mol Biol 318: 1351-1365, 2002.
    • (2002) J Mol Biol , vol.318 , pp. 1351-1365
    • Ma, Y.1    Brewer, J.W.2    Diehl, J.A.3    Hendershot, L.M.4
  • 66
    • 7044220129 scopus 로고    scopus 로고
    • Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo
    • Mao C, Dong D, Little E, Luo S, Lee AS. Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo. Nat Med 10: 1013-1014, 2004.
    • (2004) Nat Med , vol.10 , pp. 1013-1014
    • Mao, C.1    Dong, D.2    Little, E.3    Luo, S.4    Lee, A.S.5
  • 67
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by downregulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by downregulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21: 1249-1259, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 70
    • 0037072937 scopus 로고    scopus 로고
    • An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
    • Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 34287-34294
    • Morishima, N.1    Nakanishi, K.2    Takenouchi, H.3    Shibata, T.4    Yasuhiko, Y.5
  • 72
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic reticulum-specific apoptosis and cytotoxicity by amyloid-β
    • Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J. Caspase-12 mediates endoplasmic reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature 403: 98-103, 2003.
    • (2003) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 73
    • 34548479943 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress increases myofiber formation in vitro
    • Nakanishi K, Dohmae N, Morishima N. Endoplasmic reticulum stress increases myofiber formation in vitro. FASEB J 21: 2994-3003, 2007.
    • (2007) FASEB J , vol.21 , pp. 2994-3003
    • Nakanishi, K.1    Dohmae, N.2    Morishima, N.3
  • 74
    • 22344455409 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development
    • Nakanishi K, Sudo T, Morishima N. Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development. J Cell Biol 169: 555-560, 2005.
    • (2005) J Cell Biol , vol.169 , pp. 555-560
    • Nakanishi, K.1    Sudo, T.2    Morishima, N.3
  • 76
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16: 1345-1355, 2002.
    • (2002) Genes Dev , vol.16 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3    Saegusa, K.4    Takeda, K.5    Inoue, K.6    Hori, S.7    Kakizuka, A.8    Ichijo, H.9
  • 77
    • 0001911011 scopus 로고
    • Itai-itai disease and follow-up studies
    • edited by Nriagu JO. New York: John Wiley and Son
    • Nogawa K. Itai-itai disease and follow-up studies. In: Cadmium in the Environment, edited by Nriagu JO. New York: John Wiley and Son, 1981, p. 1-37.
    • (1981) Cadmium in the Environment , pp. 1-37
    • Nogawa, K.1
  • 78
    • 1642413540 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic β cells
    • Nozaki J, Kubota H, Yoshida H, Naitoh M, Goji J, Yoshinaga T, Mori K, Koizumi A, Nagata K. The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic β cells. Genes Cells 9: 261-270, 2004.
    • (2004) Genes Cells , vol.9 , pp. 261-270
    • Nozaki, J.1    Kubota, H.2    Yoshida, H.3    Naitoh, M.4    Goji, J.5    Yoshinaga, T.6    Mori, K.7    Koizumi, A.8    Nagata, K.9
  • 80
    • 0037361663 scopus 로고    scopus 로고
    • Intracellular mislocalization of mutant podocin and correction by chemical chaperones
    • Ohashi T, Uchida K, Uchida S, Sasaki S, Nihei H. Intracellular mislocalization of mutant podocin and correction by chemical chaperones. Histochem Cell Biol 119: 257-264, 2003.
    • (2003) Histochem Cell Biol , vol.119 , pp. 257-264
    • Ohashi, T.1    Uchida, K.2    Uchida, S.3    Sasaki, S.4    Nihei, H.5
  • 83
    • 57049104589 scopus 로고    scopus 로고
    • Okamura M, Takano Y, Hiramatsu N, Hayakawa K, Kasai A, Yao J, Kitamura M. Suppression of cytokine response in podocytes by indomethacin: involvement of unfolded protein response (Abstract). Proc BMB: 4P-0584, 2007.
    • Okamura M, Takano Y, Hiramatsu N, Hayakawa K, Kasai A, Yao J, Kitamura M. Suppression of cytokine response in podocytes by indomethacin: involvement of unfolded protein response (Abstract). Proc BMB: 4P-0584, 2007.
  • 84
    • 1842562209 scopus 로고    scopus 로고
    • An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease
    • Onuki R, Bando Y, Suyama E, Katayama T, Kawasaki H, Baba T, Tohyama M, Taira K. An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease. EMBO J 23: 959-968, 2004.
    • (2004) EMBO J , vol.23 , pp. 959-968
    • Onuki, R.1    Bando, Y.2    Suyama, E.3    Katayama, T.4    Kawasaki, H.5    Baba, T.6    Tohyama, M.7    Taira, K.8
  • 86
    • 0345535616 scopus 로고    scopus 로고
    • Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells
    • Outinen PA, Sood SK, Pfeifer SI, Pamidi S, Podor TJ, Li J, Weitz JI, Austin RC. Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells. Blood 94: 959-967, 1999.
    • (1999) Blood , vol.94 , pp. 959-967
    • Outinen, P.A.1    Sood, S.K.2    Pfeifer, S.I.3    Pamidi, S.4    Podor, T.J.5    Li, J.6    Weitz, J.I.7    Austin, R.C.8
  • 87
    • 0036175128 scopus 로고    scopus 로고
    • Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
    • Oyadomari S, Koizumi A, Takeda K, Gotoh T, Akira S, Araki E, Mori M. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J Clin Invest 109: 525-532, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 525-532
    • Oyadomari, S.1    Koizumi, A.2    Takeda, K.3    Gotoh, T.4    Akira, S.5    Araki, E.6    Mori, M.7
  • 90
    • 0035872446 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone
    • Ozawa K, Tsukamoto Y, Hori O, Kitao Y, Yanagi H, Stern DM, Ogawa S. Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone. Cancer Res 61: 4206-4213, 2001.
    • (2001) Cancer Res , vol.61 , pp. 4206-4213
    • Ozawa, K.1    Tsukamoto, Y.2    Hori, O.3    Kitao, Y.4    Yanagi, H.5    Stern, D.M.6    Ogawa, S.7
  • 92
    • 0029001576 scopus 로고
    • A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-κB
    • Pahl HL, Baeuerle PA. A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-κB. EMBO J 14: 2580-2588, 1995.
    • (1995) EMBO J , vol.14 , pp. 2580-2588
    • Pahl, H.L.1    Baeuerle, P.A.2
  • 93
    • 34247144663 scopus 로고    scopus 로고
    • Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines
    • Peyrou M, Cribb AE. Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines. Toxicol In Vitro 21: 878-886, 2007.
    • (2007) Toxicol In Vitro , vol.21 , pp. 878-886
    • Peyrou, M.1    Cribb, A.E.2
  • 94
    • 34547918307 scopus 로고    scopus 로고
    • Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys
    • Peyrou M, Hanna PE, Cribb AE. Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys. Toxicol Sci 99: 346-353, 2007.
    • (2007) Toxicol Sci , vol.99 , pp. 346-353
    • Peyrou, M.1    Hanna, P.E.2    Cribb, A.E.3
  • 96
    • 0028825972 scopus 로고    scopus 로고
    • Effects of glutathione depletion on the cytotoxic actions of cadmium in LLC-PK1 cells
    • Prozialeck WC, Lamar PC. Effects of glutathione depletion on the cytotoxic actions of cadmium in LLC-PK1 cells. Toxicol Appl Pharmacol 134: 285-295, 2005.
    • (2005) Toxicol Appl Pharmacol , vol.134 , pp. 285-295
    • Prozialeck, W.C.1    Lamar, P.C.2
  • 99
    • 33646860572 scopus 로고    scopus 로고
    • Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke
    • Rissanen A, Sivenius J, Jolkkonen J. Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke. Brain Res 1087: 60-66, 2006.
    • (2006) Brain Res , vol.1087 , pp. 60-66
    • Rissanen, A.1    Sivenius, J.2    Jolkkonen, J.3
  • 100
    • 0026078463 scopus 로고
    • Biogenesis of the endoplasmic reticulum in activated B lymphocytes: Temporal relationships between the induction of protein N-glycosylation activity and the biosynthesis of membrane protein and phospholipid
    • Rush JS, Sweitzer T, Kent C, Decker GL, Waechter CJ. Biogenesis of the endoplasmic reticulum in activated B lymphocytes: temporal relationships between the induction of protein N-glycosylation activity and the biosynthesis of membrane protein and phospholipid. Arch Biochem Biophys 284: 63-70, 1991.
    • (1991) Arch Biochem Biophys , vol.284 , pp. 63-70
    • Rush, J.S.1    Sweitzer, T.2    Kent, C.3    Decker, G.L.4    Waechter, C.J.5
  • 101
    • 42549112186 scopus 로고    scopus 로고
    • Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder
    • In press
    • Sawada N, Yao J, Hiramatsu N, Hayakawa K, Araki I, Takeda M, Kitamura M. Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder. Lab Invest In press.
    • Lab Invest
    • Sawada, N.1    Yao, J.2    Hiramatsu, N.3    Hayakawa, K.4    Araki, I.5    Takeda, M.6    Kitamura, M.7
  • 104
    • 10444226462 scopus 로고    scopus 로고
    • ER stress and the unfolded protein response
    • Schroder M, Kaufman RJ. ER stress and the unfolded protein response. Mutat Res 569: 29-63, 2005.
    • (2005) Mutat Res , vol.569 , pp. 29-63
    • Schroder, M.1    Kaufman, R.J.2
  • 105
    • 33646190885 scopus 로고    scopus 로고
    • The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases
    • Sekine Y, Takeda K, Ichijo H. The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases. Curr Mol Med 6: 87-97, 2006.
    • (2006) Curr Mol Med , vol.6 , pp. 87-97
    • Sekine, Y.1    Takeda, K.2    Ichijo, H.3
  • 106
    • 32044462724 scopus 로고    scopus 로고
    • Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells
    • Shao L, Sun X, Xu L, Young LT, Wang JF. Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells. Life Sci 78: 1317-1323, 2006.
    • (2006) Life Sci , vol.78 , pp. 1317-1323
    • Shao, L.1    Sun, X.2    Xu, L.3    Young, L.T.4    Wang, J.F.5
  • 107
    • 33846234333 scopus 로고    scopus 로고
    • Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: Impact on chronic inflammation
    • Shkoda A, Ruiz PA, Daniel H, Kim SC, Rogler G, Sartor RB, Haller D. Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation. Gastroenterology 132: 190-207, 2007.
    • (2007) Gastroenterology , vol.132 , pp. 190-207
    • Shkoda, A.1    Ruiz, P.A.2    Daniel, H.3    Kim, S.C.4    Rogler, G.5    Sartor, R.B.6    Haller, D.7
  • 111
    • 0346014856 scopus 로고    scopus 로고
    • Nephrotoxicity and the proximal tubule. Insights from cadmium
    • Thevenod F. Nephrotoxicity and the proximal tubule. Insights from cadmium. Nephron Physiol 93: 87-93, 2003.
    • (2003) Nephron Physiol , vol.93 , pp. 87-93
    • Thevenod, F.1
  • 112
    • 0034695660 scopus 로고    scopus 로고
    • Upregulation of multidrug resistance P-glycoprotein via NF-κB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis
    • Thevenod F, Friedmann JM, Katsen AD, Hauser IA. Upregulation of multidrug resistance P-glycoprotein via NF-κB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. J Biol Chem 275: 1887-1896, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 1887-1896
    • Thevenod, F.1    Friedmann, J.M.2    Katsen, A.D.3    Hauser, I.A.4
  • 114
    • 0034175876 scopus 로고    scopus 로고
    • Apoptotic mechanisms in acute renal failure
    • Ueda N, Kaushal GP, Shah SV. Apoptotic mechanisms in acute renal failure. Am J Med 108: 403-415, 2000.
    • (2000) Am J Med , vol.108 , pp. 403-415
    • Ueda, N.1    Kaushal, G.P.2    Shah, S.V.3
  • 115
    • 0034723235 scopus 로고    scopus 로고
    • Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
    • Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, Ron D. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287: 664-666, 2000.
    • (2000) Science , vol.287 , pp. 664-666
    • Urano, F.1    Wang, X.2    Bertolotti, A.3    Zhang, Y.4    Chung, P.5    Harding, H.P.6    Ron, D.7
  • 116
    • 0942301312 scopus 로고    scopus 로고
    • Proteomic analysis of long-term vasopressin action in the inner medullary collecting duct of the Brattleboro rat
    • van Balkom BW, Hoffert JD, Chou CL, Knepper MA. Proteomic analysis of long-term vasopressin action in the inner medullary collecting duct of the Brattleboro rat. Am J Physiol Renal Physiol 286: F216-F224, 2004.
    • (2004) Am J Physiol Renal Physiol , vol.286
    • van Balkom, B.W.1    Hoffert, J.D.2    Chou, C.L.3    Knepper, M.A.4
  • 120
    • 33645156429 scopus 로고    scopus 로고
    • From acute ER stress to physiological roles of the unfolded protein response
    • Wu J, Kaufman RJ. From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 13: 374-384, 2006.
    • (2006) Cell Death Differ , vol.13 , pp. 374-384
    • Wu, J.1    Kaufman, R.J.2
  • 121
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115: 2656-2664, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 123
    • 7944232052 scopus 로고    scopus 로고
    • Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response
    • Xu W, Liu L, Charles IG, Moncada S. Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response. Nat Cell Biol 6: 1129-1134, 2004.
    • (2004) Nat Cell Biol , vol.6 , pp. 1129-1134
    • Xu, W.1    Liu, L.2    Charles, I.G.3    Moncada, S.4
  • 127
    • 34250799639 scopus 로고    scopus 로고
    • Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats
    • Yi F, dos Santos EA, Xia M, Chen QZ, Li PL, Li N. Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats. Am J Nephrol 27: 262-268, 2007.
    • (2007) Am J Nephrol , vol.27 , pp. 262-268
    • Yi, F.1    dos Santos, E.A.2    Xia, M.3    Chen, Q.Z.4    Li, P.L.5    Li, N.6
  • 128
    • 38349003348 scopus 로고    scopus 로고
    • Mechanisms of homocysteine-induced glomerular injury and sclerosis
    • Yi F, Li PL. Mechanisms of homocysteine-induced glomerular injury and sclerosis. Am J Nephrol 28: 254-264, 2007.
    • (2007) Am J Nephrol , vol.28 , pp. 254-264
    • Yi, F.1    Li, P.L.2
  • 129
    • 34447643064 scopus 로고    scopus 로고
    • Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response
    • Yokouchi M, Hiramatsu N, Hayakawa K, Kasai A, Takano Y, Yao J, Kitamura M. Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response. Cell Death Differ 14: 1467-1474, 2007.
    • (2007) Cell Death Differ , vol.14 , pp. 1467-1474
    • Yokouchi, M.1    Hiramatsu, N.2    Hayakawa, K.3    Kasai, A.4    Takano, Y.5    Yao, J.6    Kitamura, M.7
  • 131
    • 33749579383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress triggers autophagy
    • Yorimitsu T, Nair U, Yang Z, Klionsky DJ. Endoplasmic reticulum stress triggers autophagy. J Biol Chem 281: 30299-30304, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 30299-30304
    • Yorimitsu, T.1    Nair, U.2    Yang, Z.3    Klionsky, D.J.4
  • 132
    • 33846548110 scopus 로고    scopus 로고
    • ER stress and diseases
    • Yoshida H. ER stress and diseases. FEBS J 274: 630-658, 2007.
    • (2007) FEBS J , vol.274 , pp. 630-658
    • Yoshida, H.1
  • 134
    • 14944371187 scopus 로고    scopus 로고
    • The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis
    • Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest 115: 268-281, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 268-281
    • Zhang, K.1    Wong, H.N.2    Song, B.3    Miller, C.N.4    Scheuner, D.5    Kaufman, R.J.6
  • 135
    • 0036091476 scopus 로고    scopus 로고
    • The PERK eukaryotic initiation factor 2 α kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas
    • Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR. The PERK eukaryotic initiation factor 2 α kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas. Mol Cell Biol 22: 3864-3874, 2002.
    • (2002) Mol Cell Biol , vol.22 , pp. 3864-3874
    • Zhang, P.1    McGrath, B.2    Li, S.3    Frank, A.4    Zambito, F.5    Reinert, J.6    Gannon, M.7    Ma, K.8    McNaughton, K.9    Cavener, D.R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.