Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion

Oncogene

Volumn 24, Issue 31, 2005, Pages 4921-4933

  Benali Furet, Naoual L ^a,b   Chami, Mounia ^c   Houel, Ludivine ^a,b   De Giorgi, Francesca ^d   Vernejoul, Fabienne ^e   Lagorce, David ^a,b   Buscail, Louis ^e   Bartenschlager, Ralf ^f   Ichas, François ^d   Rizzuto, Rosario ^c   Paterlini Bréchot, Patrizia ^a,b  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF FERRARA   (Italy)

^d INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

^e CHU RANGUEIL   (France)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Apoptosis; Calcium signalling; ER stress; HCV core; Liver cancer

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); AEQUORIN; CALRETICULIN; CASPASE 3; CYTOCHROME C; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN BAX;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM DEPLETION; CALCIUM SIGNALING; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPLICON; VIRUS CORE;

ANIMALS; APOPTOSIS; CALCIUM; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; HEPACIVIRUS; HUMANS; IN SITU NICK-END LABELING; INTRACELLULAR MEMBRANES; LIVER; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; MODELS, BIOLOGICAL; PROMOTER REGIONS (GENETICS); TRANSFECTION;

HEPATITIS C VIRUS; MUS MUSCULUS;

EID: 23744461982     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208673     Document Type: Article

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