Mechanisms of mitochondrial targeting of cytochrome P450 2E1: Physiopathological role in liver injury and obesity

FEBS Journal

Volumn 278, Issue 22, 2011, Pages 4252-4260

  Knockaert, Laetitia ^a,b   Fromenty, Bernard ^a,b   Robin, Marie Anne ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

cytochrome P450 2E1; liver diseases; mitochondria; obesity; targeting

Indexed keywords

CYTOCHROME P450 2E1; GLUTATHIONE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HYDROGEN PEROXIDE; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; TRANSPORTER OF THE OUTER MEMBRANE 20 PROTEIN; TRANSPORTER OF THE OUTER MEMBRANE 22 PROTEIN; TRANSPORTER OF THE OUTER MEMBRANE 40 PROTEIN; TRANSPORTER OF THE OUTER MEMBRANE 70 PROTEIN; UNCLASSIFIED DRUG;

ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME LOCALIZATION; HUMAN; IN VIVO STUDY; LIPID PEROXIDATION; LIVER INJURY; MITOCHONDRIAL MEMBRANE; MOLECULAR PATHOLOGY; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT; REVIEW; UPREGULATION;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; CYTOCHROME P-450 CYP2E1; DRUG-INDUCED LIVER INJURY; ETHANOL; HUMANS; MITOCHONDRIA; OBESITY; OXIDATIVE STRESS; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES;

EID: 80255126097     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08357.x     Document Type: Review

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