The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where

Pharmacology and Therapeutics

Volumn 154, Issue , 2015, Pages 36-56

  Pateras, Ioannis S ^a   Havaki, Sophia ^a   Nikitopoulou, Xenia ^a   Vougas, Konstantinos ^b   Townsend, Paul A ^c,d   Panayiotidis, Michalis I ^e   Georgakilas, Alexandros G ^f   Gorgoulis, Vassilis G ^a,b,c,d  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e HERIOT WATT UNIVERSITY   (United Kingdom)

^f NATIONAL TECHNICAL UNIVERSITY OF ATHENS   (Greece)

Author keywords

Autoimmunity; Cancer; DNA damage response and repair machinery; Immune response; Inflammation; Pattern recognition receptors

Indexed keywords

CHECKPOINT KINASE 2; EXTRACHROMOSOMAL DNA; GRANULOCYTE COLONY STIMULATING FACTOR; HISTONE H2AX; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 33; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MYC PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN P53; STAT1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN A; AUTACOID;

ADAPTIVE IMMUNITY; CD8+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; DNA DAMAGE; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; IMMUNOSURVEILLANCE; IONIZING RADIATION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; CELLULAR IMMUNITY; DNA REPAIR; DNA VIRUS INFECTION; IMMUNOLOGY; PHYSIOLOGY; RNA VIRUS INFECTION;

DNA DAMAGE; DNA REPAIR; DNA VIRUS INFECTIONS; HUMANS; IMMUNITY, CELLULAR; INFLAMMATION MEDIATORS; NF-KAPPA B; RADIATION, IONIZING; RNA VIRUS INFECTIONS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84941421013     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2015.06.011     Document Type: Review

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