메뉴 건너뛰기




Volumn 8, Issue 12, 2008, Pages 958-969

Exploring the full spectrum of macrophage activation

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CX3CR1; INTERLEUKIN 13; INTERLEUKIN 4;

EID: 56749174940     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri2448     Document Type: Review
Times cited : (7122)

References (119)
  • 1
    • 45549090235 scopus 로고    scopus 로고
    • Metchnikoff's legacy in 2008
    • Nathan, C. Metchnikoff's legacy in 2008. Nature Immunol. 9, 695-698 (2008).
    • (2008) Nature Immunol , vol.9 , pp. 695-698
    • Nathan, C.1
  • 2
    • 41149118513 scopus 로고    scopus 로고
    • How dying cells alert the immune system to danger
    • Kono, H. & Rock, K. L. How dying cells alert the immune system to danger. Nature Rev. Immunol. 8, 279-289 (2008).
    • (2008) Nature Rev. Immunol , vol.8 , pp. 279-289
    • Kono, H.1    Rock, K.L.2
  • 3
    • 34547656330 scopus 로고    scopus 로고
    • Immunological consequences of apoptotic cell phagocytosis
    • Erwig, L. P. & Henson, P. M. Immunological consequences of apoptotic cell phagocytosis. Am. J. Pathol. 171, 2-8 (2007).
    • (2007) Am. J. Pathol , vol.171 , pp. 2-8
    • Erwig, L.P.1    Henson, P.M.2
  • 4
    • 38549136572 scopus 로고    scopus 로고
    • Macrophage activation by endogenous danger signals
    • Zhang, X. & Mosser, D. M. Macrophage activation by endogenous danger signals. J. Pathol. 214, 161-178 (2008).
    • (2008) J. Pathol , vol.214 , pp. 161-178
    • Zhang, X.1    Mosser, D.M.2
  • 5
    • 34447116244 scopus 로고    scopus 로고
    • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
    • Chen, C. J. et al. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nature Med. 13, 851-856 (2007).
    • (2007) Nature Med , vol.13 , pp. 851-856
    • Chen, C.J.1
  • 6
    • 1542380035 scopus 로고    scopus 로고
    • Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
    • Park, J. S. et al. Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J. Biol. Chem. 279, 7370-7377 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 7370-7377
    • Park, J.S.1
  • 7
    • 0017731240 scopus 로고
    • Cellular immunity and the parasite
    • Mackaness, G. B. Cellular immunity and the parasite. Adv. Exp. Med. Biol. 93, 65-73 (1977).
    • (1977) Adv. Exp. Med. Biol , vol.93 , pp. 65-73
    • Mackaness, G.B.1
  • 8
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. Alternative activation of macrophages. Nature Rev. Immunol. 3, 23-35 (2003).
    • (2003) Nature Rev. Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 9
    • 38449102676 scopus 로고    scopus 로고
    • Martinez, F. O., Sica, A., Mantovani, A. & Locati, M. Macrophage activation and polarization. Front. Biosci. 13, 453-461 (2008). In this paper the authors proposed that the M1 and M2 designation for macrophages should be primarily based on the ratio of IL-12 to IL-10 production.
    • Martinez, F. O., Sica, A., Mantovani, A. & Locati, M. Macrophage activation and polarization. Front. Biosci. 13, 453-461 (2008). In this paper the authors proposed that the M1 and M2 designation for macrophages should be primarily based on the ratio of IL-12 to IL-10 production.
  • 10
    • 33845398215 scopus 로고    scopus 로고
    • Edwards, J. P., Zhang, X., Frauwirth, K. A. & Mosser, D. M. Biochemical and functional characterization of three activated macrophage populations. J. Leukoc. Biol. 80, 1298-1307 (2006). This work shows that alternatively activated macrophages are biochemically and functionally distinct from regulatory macrophages.
    • Edwards, J. P., Zhang, X., Frauwirth, K. A. & Mosser, D. M. Biochemical and functional characterization of three activated macrophage populations. J. Leukoc. Biol. 80, 1298-1307 (2006). This work shows that alternatively activated macrophages are biochemically and functionally distinct from regulatory macrophages.
  • 11
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon, S. & Taylor, P. R. Monocyte and macrophage heterogeneity. Nature Rev. Immunol. 5, 953-964 (2005).
    • (2005) Nature Rev. Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 12
    • 36549033197 scopus 로고    scopus 로고
    • The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
    • Nahrendorf, M. et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 204, 3037-3047 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 3037-3047
    • Nahrendorf, M.1
  • 13
    • 1642406217 scopus 로고    scopus 로고
    • Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response
    • Sunderkotter, C. et al. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J. Immunol. 172, 4410-4417 (2004).
    • (2004) J. Immunol , vol.172 , pp. 4410-4417
    • Sunderkotter, C.1
  • 14
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • This study shows that distinct monocyte populations exist, and have different cell-surface markers and homing capacities
    • Geissmann, F., Jung, S. & Littman, D. R. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19, 71-82 (2003). This study shows that distinct monocyte populations exist, and have different cell-surface markers and homing capacities.
    • (2003) Immunity , vol.19 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 15
    • 34547730844 scopus 로고    scopus 로고
    • Monocyte subpopulations and their differentiation patterns during infection
    • Strauss-Ayali, D., Conrad, S. M. & Mosser, D. M. Monocyte subpopulations and their differentiation patterns during infection. J. Leukoc. Biol. 82, 244-252 (2007).
    • (2007) J. Leukoc. Biol , vol.82 , pp. 244-252
    • Strauss-Ayali, D.1    Conrad, S.M.2    Mosser, D.M.3
  • 16
    • 0024450489 scopus 로고
    • Identification and characterization of a novel monocyte subpopulation in human peripheral blood
    • Passlick, B., Flieger, D. & Ziegler-Heitbrock, H. W. Identification and characterization of a novel monocyte subpopulation in human peripheral blood. Blood 74, 2527-2534 (1989).
    • (1989) Blood , vol.74 , pp. 2527-2534
    • Passlick, B.1    Flieger, D.2    Ziegler-Heitbrock, H.W.3
  • 17
    • 0033403066 scopus 로고    scopus 로고
    • Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
    • Randolph, G. J., Inaba, K., Robbiani, D. F., Steinman, R. M. & Muller, W. A. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity 11, 753-761 (1999).
    • (1999) Immunity , vol.11 , pp. 753-761
    • Randolph, G.J.1    Inaba, K.2    Robbiani, D.F.3    Steinman, R.M.4    Muller, W.A.5
  • 18
    • 34547728312 scopus 로고    scopus 로고
    • Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior
    • Auffray, C. et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 317, 666-670 (2007).
    • (2007) Science , vol.317 , pp. 666-670
    • Auffray, C.1
  • 19
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • Ajami, B., Bennett, J. L., Krieger, C., Tetzlaff, W. & Rossi, F. M. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nature Neurosci. 10, 1538-1543 (2007).
    • (2007) Nature Neurosci , vol.10 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.5
  • 20
    • 36249032544 scopus 로고    scopus 로고
    • The macrophage: Past, present and future
    • Gordon, S. The macrophage: past, present and future. Eur. J. Immunol. 37, S9-S17 (2007).
    • (2007) Eur. J. Immunol , vol.37
    • Gordon, S.1
  • 21
    • 41549107522 scopus 로고    scopus 로고
    • Cytokine signaling modules in inflammatory responses
    • O'Shea, J. J. & Murray, P. J. Cytokine signaling modules in inflammatory responses. Immunity 28, 477-487 (2008).
    • (2008) Immunity , vol.28 , pp. 477-487
    • O'Shea, J.J.1    Murray, P.J.2
  • 22
    • 51649127081 scopus 로고    scopus 로고
    • The phagocytes: Neutrophils and monocytes
    • Dale, D. C., Boxer, L. & Liles, W. C. The phagocytes: neutrophils and monocytes. Blood 112, 935-945 (2008).
    • (2008) Blood , vol.112 , pp. 935-945
    • Dale, D.C.1    Boxer, L.2    Liles, W.C.3
  • 23
    • 0043176281 scopus 로고    scopus 로고
    • Yamamoto, M. et al. Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 301, 640-643 (2003). This work shows that mice lacking the TLR adaptor molecule TRIF are defective in TLR3- and TLR4-mediated IFNγ production.
    • Yamamoto, M. et al. Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 301, 640-643 (2003). This work shows that mice lacking the TLR adaptor molecule TRIF are defective in TLR3- and TLR4-mediated IFNγ production.
  • 24
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish, C. L. et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201, 233-240 (2005).
    • (2005) J. Exp. Med , vol.201 , pp. 233-240
    • Langrish, C.L.1
  • 25
    • 32244442562 scopus 로고    scopus 로고
    • TGF? in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M. & Stockinger, B. TGF? in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24, 179-189 (2006).
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 26
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E. et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238 (2006).
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1
  • 27
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls, J. K. & Linden, A. Interleukin-17 family members and inflammation. Immunity 21, 467-476 (2004).
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 28
    • 0032519925 scopus 로고    scopus 로고
    • Fadok, V. A. et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF. J. Clin. Invest. 101, 890-898 (1998). This work shows that the phagocytosis of apoptotic cells by macrophages is associated with the production of TGFβ, which inhibits the production of pro-inflammatory cytokines.
    • Fadok, V. A. et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF. J. Clin. Invest. 101, 890-898 (1998). This work shows that the phagocytosis of apoptotic cells by macrophages is associated with the production of TGFβ, which inhibits the production of pro-inflammatory cytokines.
  • 29
    • 33749600724 scopus 로고    scopus 로고
    • Inborn errors of IL-12/23- and IFN-γ-mediated immunity: Molecular, cellular, and clinical features
    • Filipe-Santos, O. et al. Inborn errors of IL-12/23- and IFN-γ-mediated immunity: molecular, cellular, and clinical features. Semin. Immunol. 18, 347-361 (2006).
    • (2006) Semin. Immunol , vol.18 , pp. 347-361
    • Filipe-Santos, O.1
  • 30
    • 0028827229 scopus 로고
    • Attenuation of γ interferoninduced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: Selective inhibition of signaling through Janus kinases and Stat1
    • Nandan, D. & Reiner, N. E. Attenuation of γ interferoninduced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1. Infect. Immun. 63, 4495-4500 (1995).
    • (1995) Infect. Immun , vol.63 , pp. 4495-4500
    • Nandan, D.1    Reiner, N.E.2
  • 31
    • 0037530648 scopus 로고    scopus 로고
    • Inhibition of IFN-γ-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: A potential mechanism for immune evasion
    • Pai, R. K., Convery, M., Hamilton, T. A., Boom, W. H. & Harding, C. V. Inhibition of IFN-γ-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: a potential mechanism for immune evasion. J. Immunol. 171, 175-184 (2003).
    • (2003) J. Immunol , vol.171 , pp. 175-184
    • Pai, R.K.1    Convery, M.2    Hamilton, T.A.3    Boom, W.H.4    Harding, C.V.5
  • 32
    • 34247127472 scopus 로고    scopus 로고
    • Macrophages and their products in rheumatoid arthritis
    • Szekanecz, Z. & Koch, A. E. Macrophages and their products in rheumatoid arthritis. Curr. Opin. Rheumatol. 19, 289-295 (2007).
    • (2007) Curr. Opin. Rheumatol , vol.19 , pp. 289-295
    • Szekanecz, Z.1    Koch, A.E.2
  • 33
    • 35748964164 scopus 로고    scopus 로고
    • + T cells to be sustained during chronic infection
    • This study shows that the production of IL-4 and IL-13 is a rapid innate immune response to tissue injury
    • + T cells to be sustained during chronic infection. J. Immunol. 179, 3926-3936 (2007). This study shows that the production of IL-4 and IL-13 is a rapid innate immune response to tissue injury.
    • (2007) J. Immunol , vol.179 , pp. 3926-3936
    • Loke, P.1
  • 34
    • 0033848753 scopus 로고    scopus 로고
    • Brandt, E., Woerly, G., Younes, A. B., Loiseau, S. & Capron, M. IL-4 production by human polymorphonuclear neutrophils. J. Leukoc. Biol. 68, 125-130 (2000).
    • Brandt, E., Woerly, G., Younes, A. B., Loiseau, S. & Capron, M. IL-4 production by human polymorphonuclear neutrophils. J. Leukoc. Biol. 68, 125-130 (2000).
  • 35
    • 34247626970 scopus 로고    scopus 로고
    • Reese, T. A. et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447, 92-96 (2007). This work demonstrates that chitin induces the production of IL-4 by eosinophils and basophils.
    • Reese, T. A. et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447, 92-96 (2007). This work demonstrates that chitin induces the production of IL-4 by eosinophils and basophils.
  • 37
    • 0026762988 scopus 로고    scopus 로고
    • Stein, M., Keshav, S., Harris, N. & Gordon, S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176, 287-292 (1992). This is the initial observation that IL-4 upregulates the expression of macrophage mannose receptor, thereby giving rise to the term alternative activation.
    • Stein, M., Keshav, S., Harris, N. & Gordon, S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176, 287-292 (1992). This is the initial observation that IL-4 upregulates the expression of macrophage mannose receptor, thereby giving rise to the term alternative activation.
  • 38
    • 34548013962 scopus 로고    scopus 로고
    • Alternatively activated macrophages in protozoan infections
    • Raes, G., Beschin, A., Ghassabeh, G. H. & De, B. P. Alternatively activated macrophages in protozoan infections. Curr. Opin. Immunol. 19, 454-459 (2007).
    • (2007) Curr. Opin. Immunol , vol.19 , pp. 454-459
    • Raes, G.1    Beschin, A.2    Ghassabeh, G.H.3    De, B.P.4
  • 39
    • 33947169352 scopus 로고    scopus 로고
    • Immunopathology of schistosomiasis
    • Wilson, M. S. et al. Immunopathology of schistosomiasis. Immunol. Cell Biol. 85, 148-154 (2007).
    • (2007) Immunol. Cell Biol , vol.85 , pp. 148-154
    • Wilson, M.S.1
  • 40
    • 16544392791 scopus 로고    scopus 로고
    • Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells
    • Cordeiro-da-Silva, A. et al. Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells. Int. Immunopharmacol. 4, 547-556 (2004).
    • (2004) Int. Immunopharmacol , vol.4 , pp. 547-556
    • Cordeiro-da-Silva, A.1
  • 41
    • 33746806604 scopus 로고    scopus 로고
    • H2 cells induce alternatively activated macrophages to mediate protection against nematode parasites
    • H2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nature Med. 12, 955-960 (2006).
    • (2006) Nature Med , vol.12 , pp. 955-960
    • Anthony, R.M.1
  • 42
    • 46249106875 scopus 로고    scopus 로고
    • Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages
    • Zhao, A. et al. Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology 135, 217-225 (2008).
    • (2008) Gastroenterology , vol.135 , pp. 217-225
    • Zhao, A.1
  • 43
    • 0036553909 scopus 로고    scopus 로고
    • Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages
    • Raes, G. et al. Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J. Leukoc. Biol. 71, 597-602 (2002).
    • (2002) J. Leukoc. Biol , vol.71 , pp. 597-602
    • Raes, G.1
  • 44
    • 33645727755 scopus 로고    scopus 로고
    • Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway
    • Kzhyshkowska, J. et al. Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway. Blood 107, 3221-3228 (2006).
    • (2006) Blood , vol.107 , pp. 3221-3228
    • Kzhyshkowska, J.1
  • 45
    • 2942668626 scopus 로고    scopus 로고
    • Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation
    • Zhu, Z. et al. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science 304, 1678-1682 (2004).
    • (2004) Science , vol.304 , pp. 1678-1682
    • Zhu, Z.1
  • 47
    • 0037067670 scopus 로고    scopus 로고
    • Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins
    • Fusetti, F. et al. Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins. J. Biol. Chem. 277, 25537-25544 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 25537-25544
    • Fusetti, F.1
  • 48
    • 0035576207 scopus 로고    scopus 로고
    • Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of l-arginine metabolism
    • H2-type cytokines and inversely correlates with nitric oxide production
    • H2-type cytokines and inversely correlates with nitric oxide production.
    • (2001) J. Immunol , vol.167 , pp. 6533-6544
    • Hesse, M.1
  • 49
    • 44449167278 scopus 로고    scopus 로고
    • Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis
    • Munitz, A., Brandt, E. B., Mingler, M., Finkelman, F. D. & Rothenberg, M. E. Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis. Proc. Natl Acad. Sci. USA 105, 7240-7245 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 7240-7245
    • Munitz, A.1    Brandt, E.B.2    Mingler, M.3    Finkelman, F.D.4    Rothenberg, M.E.5
  • 50
    • 34548700401 scopus 로고    scopus 로고
    • T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis
    • Harris, J. et al. T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. Immunity 27, 505-517 (2007).
    • (2007) Immunity , vol.27 , pp. 505-517
    • Harris, J.1
  • 51
    • 20444497730 scopus 로고    scopus 로고
    • Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo
    • Kropf, P. et al. Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo. FASEB J. 19, 1000-1002 (2005).
    • (2005) FASEB J , vol.19 , pp. 1000-1002
    • Kropf, P.1
  • 52
    • 38449096612 scopus 로고    scopus 로고
    • IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans
    • Muller, U. et al. IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans. J. Immunol. 179, 5367-5377 (2007).
    • (2007) J. Immunol , vol.179 , pp. 5367-5377
    • Muller, U.1
  • 53
    • 56149111288 scopus 로고    scopus 로고
    • Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism
    • Shirey, K. A., Cole, L. E., Keegan, A. D. & Vogel, S. N. Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. J. Immunol. 181, 4159-4167 (2008).
    • (2008) J. Immunol , vol.181 , pp. 4159-4167
    • Shirey, K.A.1    Cole, L.E.2    Keegan, A.D.3    Vogel, S.N.4
  • 54
    • 35448932701 scopus 로고    scopus 로고
    • Pattern of macrophage activation in Yersinia-resistant and Yersinia-susceptible strains of mice
    • Tumitan, A. R., Monnazzi, L. G., Ghiraldi, F. R., Cilli, E. M. & hado de Medeiros, B. M. Pattern of macrophage activation in Yersinia-resistant and Yersinia-susceptible strains of mice. Microbiol. Immunol. 51, 1021-1028 (2007).
    • (2007) Microbiol. Immunol , vol.51 , pp. 1021-1028
    • Tumitan, A.R.1    Monnazzi, L.G.2    Ghiraldi, F.R.3    Cilli, E.M.4    hado de5    Medeiros, B.M.6
  • 55
    • 33645284772 scopus 로고    scopus 로고
    • Neural regulation of innate immunity: A coordinated nonspecific host response to pathogens
    • Sternberg, E. M. Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nature Rev. Immunol. 6, 318-328 (2006).
    • (2006) Nature Rev. Immunol , vol.6 , pp. 318-328
    • Sternberg, E.M.1
  • 56
    • 3042749817 scopus 로고    scopus 로고
    • Glucocorticoids and the Th1/Th2 balance
    • Elenkov, I. J. Glucocorticoids and the Th1/Th2 balance. Ann. N. Y. Acad. Sci. 1024, 138-146 (2004).
    • (2004) Ann. N. Y. Acad. Sci , vol.1024 , pp. 138-146
    • Elenkov, I.J.1
  • 57
    • 0033559878 scopus 로고    scopus 로고
    • Glucocorticoids promote nonphlogistic phagocytosis of apoptotic leukocytes
    • Liu, Y. et al. Glucocorticoids promote nonphlogistic phagocytosis of apoptotic leukocytes. J. Immunol. 162, 3639-3646 (1999).
    • (1999) J. Immunol , vol.162 , pp. 3639-3646
    • Liu, Y.1
  • 58
    • 3042833447 scopus 로고    scopus 로고
    • Overview of the actions of glucocorticoids on the immune response: A good model to characterize new pathways of immunosuppression for new treatment strategies
    • Franchimont, D. Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immunosuppression for new treatment strategies. Ann. NY Acad. Sci. 1024, 124-137 (2004).
    • (2004) Ann. NY Acad. Sci , vol.1024 , pp. 124-137
    • Franchimont, D.1
  • 59
    • 0037310024 scopus 로고    scopus 로고
    • The many faces of macrophage activation
    • Mosser, D. M. The many faces of macrophage activation. J. Leukoc. Biol. 73, 209-212 (2003).
    • (2003) J. Leukoc. Biol , vol.73 , pp. 209-212
    • Mosser, D.M.1
  • 60
    • 21244502077 scopus 로고    scopus 로고
    • ERK activation following macrophage FcγR ligation leads to chromatin modifications at the IL-10 locus
    • This paper shows that activation of ERK is required for the hypersecretion of IL-10 by regulatory macrophages
    • Lucas, M., Zhang, X., Prasanna, V. & Mosser, D. M. ERK activation following macrophage FcγR ligation leads to chromatin modifications at the IL-10 locus. J. Immunol. 175, 469-477 (2005). This paper shows that activation of ERK is required for the hypersecretion of IL-10 by regulatory macrophages.
    • (2005) J. Immunol , vol.175 , pp. 469-477
    • Lucas, M.1    Zhang, X.2    Prasanna, V.3    Mosser, D.M.4
  • 61
    • 0035337139 scopus 로고    scopus 로고
    • Reversing lipopolysaccharide toxicity by ligating the macrophage Fcγ receptors
    • Gerber, J. S. & Mosser, D. M. Reversing lipopolysaccharide toxicity by ligating the macrophage Fcγ receptors. J. Immunol. 166, 6861-6868 (2001).
    • (2001) J. Immunol , vol.166 , pp. 6861-6868
    • Gerber, J.S.1    Mosser, D.M.2
  • 62
    • 0028109394 scopus 로고
    • Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2
    • Strassmann, G., Patil-Koota, V., Finkelman, F., Fong, M. & Kambayashi, T. Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. J. Exp. Med. 180, 2365-2370 (1994).
    • (1994) J. Exp. Med , vol.180 , pp. 2365-2370
    • Strassmann, G.1    Patil-Koota, V.2    Finkelman, F.3    Fong, M.4    Kambayashi, T.5
  • 63
    • 33846434062 scopus 로고    scopus 로고
    • Shaping of monocyte and macrophage function by adenosine receptors
    • Hasko, G., Pacher, P., Deitch, E. A. & Vizi, E. S. Shaping of monocyte and macrophage function by adenosine receptors. Pharmacol. Ther. 113, 264-275 (2007).
    • (2007) Pharmacol. Ther , vol.113 , pp. 264-275
    • Hasko, G.1    Pacher, P.2    Deitch, E.A.3    Vizi, E.S.4
  • 64
    • 0036145498 scopus 로고    scopus 로고
    • Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a β-adrenoceptor-mediated mechanism
    • Hasko, G., Szabo, C., Nemeth, Z. H. & Deitch, E. A. Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a β-adrenoceptor-mediated mechanism. J. Neuroimmunol. 122, 34-39 (2002).
    • (2002) J. Neuroimmunol , vol.122 , pp. 34-39
    • Hasko, G.1    Szabo, C.2    Nemeth, Z.H.3    Deitch, E.A.4
  • 65
    • 17544401915 scopus 로고    scopus 로고
    • Importance of histamine in the cytokine network in the lung through H2 and H3 receptors: Stimulation of IL-10 production
    • Sirois, J., Menard, G., Moses, A. S. & Bissonnette, E. Y. Importance of histamine in the cytokine network in the lung through H2 and H3 receptors: stimulation of IL-10 production. J. Immunol. 164, 2964-2970 (2000).
    • (2000) J. Immunol , vol.164 , pp. 2964-2970
    • Sirois, J.1    Menard, G.2    Moses, A.S.3    Bissonnette, E.Y.4
  • 66
    • 34948853738 scopus 로고    scopus 로고
    • Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate
    • Weigert, A. et al. Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate. Mol. Biol. Cell 18, 3810-3819 (2007).
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3810-3819
    • Weigert, A.1
  • 67
    • 31544464946 scopus 로고    scopus 로고
    • Melanocortin receptor signaling in RAW264.7 macrophage cell line
    • Lam, C. W., Perretti, M. & Getting, S. J. Melanocortin receptor signaling in RAW264.7 macrophage cell line. Peptides 27, 404-412 (2006).
    • (2006) Peptides , vol.27 , pp. 404-412
    • Lam, C.W.1    Perretti, M.2    Getting, S.J.3
  • 68
    • 0033083302 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide enhance IL-10 production by murine macrophages: In vitro and in vivo studies
    • Delgado, M., Munoz-Elias, E. J., Gomariz, R. P. & Ganea, D. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide enhance IL-10 production by murine macrophages: in vitro and in vivo studies. J. Immunol. 162, 1707-1716 (1999).
    • (1999) J. Immunol , vol.162 , pp. 1707-1716
    • Delgado, M.1    Munoz-Elias, E.J.2    Gomariz, R.P.3    Ganea, D.4
  • 69
    • 40749111945 scopus 로고    scopus 로고
    • Mechanisms for the anti-inflammatory effects of adiponectin in macrophages
    • Huang, H., Park, P. H., McMullen, M. R. & Nagy, L. E. Mechanisms for the anti-inflammatory effects of adiponectin in macrophages. J. Gastroenterol. Hepatol. 1, S50-S53 (2008).
    • (2008) J. Gastroenterol. Hepatol , vol.1
    • Huang, H.1    Park, P.H.2    McMullen, M.R.3    Nagy, L.E.4
  • 70
    • 41149114476 scopus 로고    scopus 로고
    • Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs
    • Ando, M., Tu, W., Nishijima, K. & Iijima, S. Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs. Biochem. Biophys. Res. Commun. 369, 878-883 (2008).
    • (2008) Biochem. Biophys. Res. Commun , vol.369 , pp. 878-883
    • Ando, M.1    Tu, W.2    Nishijima, K.3    Iijima, S.4
  • 71
    • 33344460032 scopus 로고    scopus 로고
    • A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)
    • In this study, tumour-associated macrophages are profiled by microarray analysis
    • Biswas, S. K. et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation). Blood 107, 2112-2122 (2006). In this study, tumour-associated macrophages are profiled by microarray analysis.
    • (2006) Blood , vol.107 , pp. 2112-2122
    • Biswas, S.K.1
  • 72
    • 15444364277 scopus 로고    scopus 로고
    • A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
    • Miles, S. A., Conrad, S. M., Alves, R. G., Jeronimo, S. M. & Mosser, D. M. A role for IgG immune complexes during infection with the intracellular pathogen Leishmania. J. Exp. Med. 201, 747-754 (2005).
    • (2005) J. Exp. Med , vol.201 , pp. 747-754
    • Miles, S.A.1    Conrad, S.M.2    Alves, R.G.3    Jeronimo, S.M.4    Mosser, D.M.5
  • 73
    • 0035340424 scopus 로고    scopus 로고
    • Alternative versus classical macrophage activation during experimental African trypanosomosis
    • Baetselier, P. D. et al. Alternative versus classical macrophage activation during experimental African trypanosomosis. Int. J. Parasitol. 31, 575-587 (2001).
    • (2001) Int. J. Parasitol , vol.31 , pp. 575-587
    • Baetselier, P.D.1
  • 74
    • 43149105160 scopus 로고    scopus 로고
    • Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus
    • Kim, C. et al. Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus. Proc. Natl Acad. Sci. USA 105, 6150-6155 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 6150-6155
    • Kim, C.1
  • 75
    • 11244260655 scopus 로고    scopus 로고
    • Anthrax lethal toxin: A weapon of multisystem destruction
    • Agrawal, A. & Pulendran, B. Anthrax lethal toxin: a weapon of multisystem destruction. Cell Mol. Life Sci. 61, 2859-2865 (2004).
    • (2004) Cell Mol. Life Sci , vol.61 , pp. 2859-2865
    • Agrawal, A.1    Pulendran, B.2
  • 76
    • 44849125178 scopus 로고    scopus 로고
    • Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages
    • Benoit, M., Barbarat, B., Bernard, A., Olive, D. & Mege, J. L. Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages. Eur. J. Immunol. 38, 1065-1070 (2008).
    • (2008) Eur. J. Immunol , vol.38 , pp. 1065-1070
    • Benoit, M.1    Barbarat, B.2    Bernard, A.3    Olive, D.4    Mege, J.L.5
  • 77
    • 0037109070 scopus 로고    scopus 로고
    • Suppression of lipopolysaccharide- induced antiviral transcription factor (STAT-1 and NF-κB) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus
    • Mahalingam, S. & Lidbury, B. A. Suppression of lipopolysaccharide- induced antiviral transcription factor (STAT-1 and NF-κB) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus. Proc. Natl Acad. Sci. USA 99, 13819-13824 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13819-13824
    • Mahalingam, S.1    Lidbury, B.A.2
  • 78
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
    • Stout, R. D. et al. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J. Immunol. 175, 342-349 (2005).
    • (2005) J. Immunol , vol.175 , pp. 342-349
    • Stout, R.D.1
  • 81
    • 34347226359 scopus 로고    scopus 로고
    • Lin, E. Y. & Pollard, J. W. Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res. 67, 5064-5066 (2007). This work correlates macrophage recruitment into tumours with an angiogenic switch and a poor prognosis.
    • Lin, E. Y. & Pollard, J. W. Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res. 67, 5064-5066 (2007). This work correlates macrophage recruitment into tumours with an angiogenic switch and a poor prognosis.
  • 82
    • 38649087921 scopus 로고    scopus 로고
    • Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis
    • Swann, J. B. et al. Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis. Proc. Natl Acad. Sci. USA 105, 652-656 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 652-656
    • Swann, J.B.1
  • 83
    • 33751301603 scopus 로고    scopus 로고
    • Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages
    • Romieu-Mourez, R. et al. Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages. Cancer Res. 66, 10576-10585 (2006).
    • (2006) Cancer Res , vol.66 , pp. 10576-10585
    • Romieu-Mourez, R.1
  • 84
    • 50849090319 scopus 로고    scopus 로고
    • Macrophages define the invasive microenvironment in breast cancer
    • Pollard, J. W. Macrophages define the invasive microenvironment in breast cancer. J. Leukoc. Biol. 84, 623-630 (2008).
    • (2008) J. Leukoc. Biol , vol.84 , pp. 623-630
    • Pollard, J.W.1
  • 85
    • 0035947709 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
    • Liu, C. H. et al. Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J. Biol. Chem. 276, 18563-18569 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 18563-18569
    • Liu, C.H.1
  • 86
    • 0034842201 scopus 로고    scopus 로고
    • Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis
    • Knowles, H. J. & Harris, A. L. Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis. Breast Cancer Res. 3, 318-322 (2001).
    • (2001) Breast Cancer Res , vol.3 , pp. 318-322
    • Knowles, H.J.1    Harris, A.L.2
  • 87
    • 34547113798 scopus 로고    scopus 로고
    • Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes
    • Kuang, D. M. et al. Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes. Blood 110, 587-595 (2007).
    • (2007) Blood , vol.110 , pp. 587-595
    • Kuang, D.M.1
  • 88
    • 19344365408 scopus 로고    scopus 로고
    • De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
    • de Visser, K. E., Korets, L. V. & Coussens, L. M. De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7, 411-423 (2005).
    • (2005) Cancer Cell , vol.7 , pp. 411-423
    • de Visser, K.E.1    Korets, L.V.2    Coussens, L.M.3
  • 89
    • 45149134605 scopus 로고    scopus 로고
    • Re-educating tumor-associated macrophages by targeting NF-κB
    • Hagemann, T. et al. "Re-educating" tumor-associated macrophages by targeting NF-κB. J. Exp. Med. 205, 1261-1268 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 1261-1268
    • Hagemann, T.1
  • 90
    • 33845767868 scopus 로고    scopus 로고
    • Macrophages regulate the angiogenic switch in a mouse model of breast cancer
    • Lin, E. Y. et al. Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res. 66, 11238-11246 (2006).
    • (2006) Cancer Res , vol.66 , pp. 11238-11246
    • Lin, E.Y.1
  • 91
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng, C. N., Bodzin, J. L. & Saltiel, A. R. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 117, 175-184 (2007).
    • (2007) J. Clin. Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 92
    • 36049034344 scopus 로고    scopus 로고
    • Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms
    • Straus, D. S. & Glass, C. K. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol. 28, 551-558 (2007).
    • (2007) Trends Immunol , vol.28 , pp. 551-558
    • Straus, D.S.1    Glass, C.K.2
  • 93
    • 47149096915 scopus 로고    scopus 로고
    • Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
    • Heilbronn, L. K. & Campbell, L. V. Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr. Pharm. Des. 14, 1225-1230 (2008).
    • (2008) Curr. Pharm. Des , vol.14 , pp. 1225-1230
    • Heilbronn, L.K.1    Campbell, L.V.2
  • 94
    • 34548477639 scopus 로고    scopus 로고
    • Adipose tissue macrophages
    • Zeyda, M. & Stulnig, T. M. Adipose tissue macrophages. Immunol. Lett. 112, 61-67 (2007).
    • (2007) Immunol. Lett , vol.112 , pp. 61-67
    • Zeyda, M.1    Stulnig, T.M.2
  • 95
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti, S. et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J. Lipid Res. 46, 2347-2355 (2005).
    • (2005) J. Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1
  • 96
    • 33745896155 scopus 로고    scopus 로고
    • Recent advances in the relationship between obesity, inflammation, and insulin resistance
    • Bastard, J. P. et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur. Cytokine Netw. 17, 4-12 (2006).
    • (2006) Eur. Cytokine Netw , vol.17 , pp. 4-12
    • Bastard, J.P.1
  • 98
    • 53149090164 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in the modulation of the immune/inflammatory response in atherosclerosis
    • Fernandez, A. Z. Peroxisome proliferator-activated receptors in the modulation of the immune/inflammatory response in atherosclerosis. PPAR Res. 2008, 285842 (2008).
    • (2008) PPAR Res , vol.2008 , pp. 285842
    • Fernandez, A.Z.1
  • 99
    • 38449108504 scopus 로고    scopus 로고
    • Individual variation of scavenger receptor expression in human macrophages with oxidized low-density lipoprotein is associated with a differential inflammatory response
    • Martin-Fuentes, P. et al. Individual variation of scavenger receptor expression in human macrophages with oxidized low-density lipoprotein is associated with a differential inflammatory response. J. Immunol. 179, 3242-3248 (2007).
    • (2007) J. Immunol , vol.179 , pp. 3242-3248
    • Martin-Fuentes, P.1
  • 100
    • 53149143588 scopus 로고    scopus 로고
    • Atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus
    • Haque, S., Mirjafari, H. & Bruce, I. N. Atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus. Curr. Opin. Lipidol. 19, 338-343 (2008).
    • (2008) Curr. Opin. Lipidol , vol.19 , pp. 338-343
    • Haque, S.1    Mirjafari, H.2    Bruce, I.N.3
  • 101
    • 45449084802 scopus 로고    scopus 로고
    • Roark, C. L., Simonian, P. L., Fontenot, A. P., Born, W. K. & O'Brien, R. L. γδ T cells: an important source of IL-17. Curr. Opin. Immunol. 20, 353-357 (2008).
    • Roark, C. L., Simonian, P. L., Fontenot, A. P., Born, W. K. & O'Brien, R. L. γδ T cells: an important source of IL-17. Curr. Opin. Immunol. 20, 353-357 (2008).
  • 102
    • 33646560950 scopus 로고    scopus 로고
    • H17 lineage
    • H17 lineage. Nature 441, 231-234 (2006).
    • (2006) Nature , vol.441 , pp. 231-234
    • Mangan, P.R.1
  • 103
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
    • costa-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A. & Sallusto, F. Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nature Immunol. 8, 942-949 (2007).
    • (2007) Nature Immunol , vol.8 , pp. 942-949
    • costa-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 104
    • 34548764423 scopus 로고    scopus 로고
    • Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
    • Denning, T. L., Wang, Y. C., Patel, S. R., Williams, I. R. & Pulendran, B. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nature Immunol. 8, 1086-1094 (2007).
    • (2007) Nature Immunol , vol.8 , pp. 1086-1094
    • Denning, T.L.1    Wang, Y.C.2    Patel, S.R.3    Williams, I.R.4    Pulendran, B.5
  • 105
    • 0032055597 scopus 로고    scopus 로고
    • IL-17 stimulates the production and expression of proinflammatory cytokines, IL-β and TNF-α, by human macrophages
    • Jovanovic, D. V. et al. IL-17 stimulates the production and expression of proinflammatory cytokines, IL-β and TNF-α, by human macrophages. J. Immunol. 160, 3513-3521 (1998).
    • (1998) J. Immunol , vol.160 , pp. 3513-3521
    • Jovanovic, D.V.1
  • 106
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • Sato, K. et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203, 2673-2682 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 2673-2682
    • Sato, K.1
  • 107
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nature Rev. Immunol. 3, 133-146 (2003).
    • (2003) Nature Rev. Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 109
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • Martinez, F. O., Gordon, S., Locati, M. & Mantovani, A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177, 7303-7311 (2006).
    • (2006) J. Immunol , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 110
    • 2642622567 scopus 로고    scopus 로고
    • Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 α with a Th2-associated expression pattern
    • Kodelja, V. et al. Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 α with a Th2-associated expression pattern. J. Immunol. 160, 1411-1418 (1998).
    • (1998) J. Immunol , vol.160 , pp. 1411-1418
    • Kodelja, V.1
  • 111
    • 0042815023 scopus 로고    scopus 로고
    • FIZZ1 and Ym as tools to discriminate between differentially activated macrophages
    • Raes, G. et al. FIZZ1 and Ym as tools to discriminate between differentially activated macrophages. Dev. Immunol. 9, 151-159 (2002).
    • (2002) Dev. Immunol , vol.9 , pp. 151-159
    • Raes, G.1
  • 112
    • 33746266258 scopus 로고    scopus 로고
    • Wirnsberger, G., Hebenstreit, D., Posselt, G., Horejs-Hoeck, J. & Duschl, A. IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites. Eur. J. Immunol. 36, 1882-1891 (2006).
    • Wirnsberger, G., Hebenstreit, D., Posselt, G., Horejs-Hoeck, J. & Duschl, A. IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites. Eur. J. Immunol. 36, 1882-1891 (2006).
  • 113
    • 33747344010 scopus 로고    scopus 로고
    • Alternatively activated macrophages express the IL-27 receptor ? chain WSX-1
    • Ruckerl, D., Hessmann, M., Yoshimoto, T., Ehlers, S. & Holscher, C. Alternatively activated macrophages express the IL-27 receptor ? chain WSX-1. Immunobiology 211, 427-436 (2006).
    • (2006) Immunobiology , vol.211 , pp. 427-436
    • Ruckerl, D.1    Hessmann, M.2    Yoshimoto, T.3    Ehlers, S.4    Holscher, C.5
  • 114
    • 0141955107 scopus 로고    scopus 로고
    • Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13
    • Wynes, M. W. & Riches, D. W. Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13. J. Immunol. 171, 3550-3559 (2003).
    • (2003) J. Immunol , vol.171 , pp. 3550-3559
    • Wynes, M.W.1    Riches, D.W.2
  • 115
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani, A., Sozzani, S., Locati, M., Allavena, P. & Sica, A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23, 549-555 (2002).
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 116
    • 0033082935 scopus 로고    scopus 로고
    • Other functions, other genes: Alternative activation of antigen presenting cells
    • Goerdt, S. & Orfanos, C. E. Other functions, other genes: alternative activation of antigen presenting cells. Immunity 10, 137-142 (1999).
    • (1999) Immunity , vol.10 , pp. 137-142
    • Goerdt, S.1    Orfanos, C.E.2
  • 117
    • 24744469246 scopus 로고    scopus 로고
    • Identification of factor XIII-A as a marker of alternative macrophage activation
    • Torocsik, D., Bardos, H., Nagy, L. & Adany, R. Identification of factor XIII-A as a marker of alternative macrophage activation. Cell. Mol. Life Sci. 62, 2132-2139 (2005).
    • (2005) Cell. Mol. Life Sci , vol.62 , pp. 2132-2139
    • Torocsik, D.1    Bardos, H.2    Nagy, L.3    Adany, R.4
  • 118
    • 33748855014 scopus 로고    scopus 로고
    • Differential regulation of chemokine production by Fcγ receptor engagement in human monocytes: Association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2)
    • Sironi, M. et al. Differential regulation of chemokine production by Fcγ receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2). J. Leukoc. Biol. 80, 342-349 (2006).
    • (2006) J. Leukoc. Biol , vol.80 , pp. 342-349
    • Sironi, M.1
  • 119
    • 41449113342 scopus 로고    scopus 로고
    • Advances in understanding the anti-inflammatory properties of IL-27
    • Stumhofer, J. S. & Hunter, C. A. Advances in understanding the anti-inflammatory properties of IL-27. Immunol. Lett. 117, 123-130 (2008).
    • (2008) Immunol. Lett , vol.117 , pp. 123-130
    • Stumhofer, J.S.1    Hunter, C.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.