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Volumn 15, Issue 20, 1996, Pages 5668-5678

Inhibition of E2F-mediated transcription by p202

Author keywords

Cell growth inhibition; E2F binding protein; Inhibition of E2F mediated transcription; Interferon inducible p202

Indexed keywords

INTERFERON; NUCLEAR PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

EID: 0029853903     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00951.x     Document Type: Article
Times cited : (101)

References (69)
  • 2
    • 0025024111 scopus 로고
    • Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: A novel mechanism for E1A transactivation
    • Bagchi, S., Raychaudhuri, P. and Nevins, J.R. (1990) Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A transactivation. Cell, 62, 659-669.
    • (1990) Cell , vol.62 , pp. 659-669
    • Bagchi, S.1    Raychaudhuri, P.2    Nevins, J.R.3
  • 3
    • 0025910802 scopus 로고
    • The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
    • Bagchi, S., Weinmann, R. and Raychaudhuri, P. (1991) The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F. Cell, 65, 1063-1072.
    • (1991) Cell , vol.65 , pp. 1063-1072
    • Bagchi, S.1    Weinmann, R.2    Raychaudhuri, P.3
  • 4
    • 0025869428 scopus 로고
    • Adenovirus E1A prevents the retinoblastoma gene product from complexing with a cellular transcription factor
    • Bandara, L.R. and La Thangue, N.B. (1991) Adenovirus E1A prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature, 351, 494-497.
    • (1991) Nature , vol.351 , pp. 494-497
    • Bandara, L.R.1    La Thangue, N.B.2
  • 5
    • 0027434084 scopus 로고
    • Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F
    • Bandara, L.R., Buck, W.M., Zamanian, M., Johnston, L.H. and La Thangue, N.B. (1993) Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J., 12, 4317-4324.
    • (1993) EMBO J. , vol.12 , pp. 4317-4324
    • Bandara, L.R.1    Buck, W.M.2    Zamanian, M.3    Johnston, L.H.4    La Thangue, N.B.5
  • 6
    • 0027985749 scopus 로고
    • E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo
    • Beijersbergen, R.L., Kerkhoven, R.M., Zhu, L., Calee, L., Voorhoven, P.M. and Bernards, R. (1994) E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev., 8, 2680-2690.
    • (1994) Genes Dev. , vol.8 , pp. 2680-2690
    • Beijersbergen, R.L.1    Kerkhoven, R.M.2    Zhu, L.3    Calee, L.4    Voorhoven, P.M.5    Bernards, R.6
  • 8
    • 0024318029 scopus 로고
    • Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo
    • Blake, M.C. and Azizkhan, J.C. (1989) Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo. Mol. Cell. Biol., 9, 4994-5002.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4994-5002
    • Blake, M.C.1    Azizkhan, J.C.2
  • 9
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for the Rb protein
    • Chellappan, S.P., Hiebert, S., Mudryj, M., Horowitz, J.M. and Nevins, J.R. (1991) The E2F transcription factor is a cellular target for the Rb protein. Cell, 65, 1053-1061.
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 10
    • 0025734783 scopus 로고
    • The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
    • Chittenden, T., Livingston, D.M. and Kaelin, W.G., Jr (1991) The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell, 65, 1073-1082.
    • (1991) Cell , vol.65 , pp. 1073-1082
    • Chittenden, T.1    Livingston, D.M.2    Kaelin Jr., W.G.3
  • 11
    • 0029868223 scopus 로고    scopus 로고
    • The interferon-inducible growth-inhibitory p202 protein: DNA binding properties and identification of a DNA binding domain
    • Choubey, D. and Gutterman, J.U. (1996) The interferon-inducible growth-inhibitory p202 protein: DNA binding properties and identification of a DNA binding domain. Biochem. Biophys. Res. Commun., 221, 396-401.
    • (1996) Biochem. Biophys. Res. Commun. , vol.221 , pp. 396-401
    • Choubey, D.1    Gutterman, J.U.2
  • 12
    • 0026581191 scopus 로고
    • Interferon action: Nucleolar and nucleoplasmic localization of the interferon-inducible 72-kDa protein that is encoded by the Ifi 204 gene from the gene 200 cluster
    • Choubey, D. and Lengyel, P. (1992) Interferon action: nucleolar and nucleoplasmic localization of the interferon-inducible 72-kDa protein that is encoded by the Ifi 204 gene from the gene 200 cluster. J. Cell Biol., 116, 1333-1341.
    • (1992) J. Cell Biol. , vol.116 , pp. 1333-1341
    • Choubey, D.1    Lengyel, P.2
  • 13
    • 0027403477 scopus 로고
    • Interferon action: Cytoplasmic and nuclear localization of the interferon-inducible 52-kDa protein that is encoded by the Ifi 202 gene from the gene 200 cluster
    • Choubey, D. and Lengyel, P. (1993) Interferon action: cytoplasmic and nuclear localization of the interferon-inducible 52-kDa protein that is encoded by the Ifi 202 gene from the gene 200 cluster. J. Interferon Res., 13, 43-52.
    • (1993) J. Interferon Res. , vol.13 , pp. 43-52
    • Choubey, D.1    Lengyel, P.2
  • 14
    • 0028933243 scopus 로고
    • Binding of an interferon-inducible protein (p202) to the retinoblastoma protein
    • Choubey, D. and Lengyel, P. (1995) Binding of an interferon-inducible protein (p202) to the retinoblastoma protein. J. Biol. Chem., 270, 6134-6140.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6134-6140
    • Choubey, D.1    Lengyel, P.2
  • 15
    • 0024317451 scopus 로고
    • Interferons as gene activators: Indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1
    • Choubey, D., Snoddy, J., Chaturvedi, V., Toniato, E., Opdenakker, G., Thakur, A., Samanta, H., Engel, D. and Lengyel, P. (1989) Interferons as gene activators: indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J. Biol. Chem., 264, 17182-17189.
    • (1989) J. Biol. Chem. , vol.264 , pp. 17182-17189
    • Choubey, D.1    Snoddy, J.2    Chaturvedi, V.3    Toniato, E.4    Opdenakker, G.5    Thakur, A.6    Samanta, H.7    Engel, D.8    Lengyel, P.9
  • 16
    • 0027140404 scopus 로고
    • Cell cycle-specific association of E2F with the p130 E1A-binding protein
    • Cobrinik, D., Whyte, P., Peeper, D.S., Jacks, T. and Weinberg, R.A. (1993) Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev., 7, 2392-2404.
    • (1993) Genes Dev. , vol.7 , pp. 2392-2404
    • Cobrinik, D.1    Whyte, P.2    Peeper, D.S.3    Jacks, T.4    Weinberg, R.A.5
  • 17
    • 0026568215 scopus 로고
    • Cell cycle regulation of the human cdc2 gene
    • Dalton, S. (1992) Cell cycle regulation of the human cdc2 gene. EMBO J., 11, 1797-1804.
    • (1992) EMBO J. , vol.11 , pp. 1797-1804
    • Dalton, S.1
  • 21
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk2 complexes
    • Dynlacht, B.D., Flores, O., Lees, J.A. and Harlow, E. (1994) Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev., 8, 1772-1786.
    • (1994) Genes Dev. , vol.8 , pp. 1772-1786
    • Dynlacht, B.D.1    Flores, O.2    Lees, J.A.3    Harlow, E.4
  • 22
    • 0004208947 scopus 로고
    • Academic Press, San Diego, CA
    • Farrell, R.E., Jr (1993) RNA Methodologies. Academic Press, San Diego, CA, pp. 235-263.
    • (1993) RNA Methodologies , pp. 235-263
    • Farrell Jr., R.E.1
  • 24
    • 0027250860 scopus 로고
    • E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product
    • Flemington, E.K., Speck, S.H. and Kaelin, W.G., Jr (1993) E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product. Proc. Natl Acad. Sci. USA, 90, 6914-6918.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 6914-6918
    • Flemington, E.K.1    Speck, S.H.2    Kaelin Jr., W.G.3
  • 26
    • 0028117299 scopus 로고
    • Cytokine therapeutics: Lessons from interferon alpha
    • Gutterman, J.U. (1994) Cytokine therapeutics: lessons from interferon alpha. Proc. Natl Acad. Sci. USA, 91, 1198-1202.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 1198-1202
    • Gutterman, J.U.1
  • 27
    • 0026769912 scopus 로고
    • Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene
    • Hamel, P.A., Gill, R.M., Phillips, R.A. and Gallie, B.L. (1992) Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene. Mol. Cell. Biol., 12, 3431-3438.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3431-3438
    • Hamel, P.A.1    Gill, R.M.2    Phillips, R.A.3    Gallie, B.L.4
  • 28
    • 0026652346 scopus 로고
    • A cDNA encoding a pRb-binding protein with properties of the transcription factor E2F
    • Helin, K., Lees, J.A., Vidal, M., Dyson, N., Harlow, E. and Fattaey, A. (1992) A cDNA encoding a pRb-binding protein with properties of the transcription factor E2F. Cell, 70, 337-350.
    • (1992) Cell , vol.70 , pp. 337-350
    • Helin, K.1    Lees, J.A.2    Vidal, M.3    Dyson, N.4    Harlow, E.5    Fattaey, A.6
  • 29
    • 0027426917 scopus 로고
    • Heterodimerization of the transcription factor E2F-1 and DP-1 leads to cooperative transactivation
    • Helin, K., Wu, C., Fattaey, A.R., Lees, J.A., Dynlacht, B.D., Ngwu, C. and Harlow, E. (1993) Heterodimerization of the transcription factor E2F-1 and DP-1 leads to cooperative transactivation. Genes Dev., 7, 1850-1861.
    • (1993) Genes Dev. , vol.7 , pp. 1850-1861
    • Helin, K.1    Wu, C.2    Fattaey, A.R.3    Lees, J.A.4    Dynlacht, B.D.5    Ngwu, C.6    Harlow, E.7
  • 30
    • 0026537277 scopus 로고
    • The interaction of pRb with E2F coincides with an inhibition of the transcriptional activity of E2F
    • Hiebert, S.W., Chellappan, S.P., Horowitz, J.M. and Nevins, J.R. (1992) The interaction of pRb with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev., 6, 177-185.
    • (1992) Genes Dev. , vol.6 , pp. 177-185
    • Hiebert, S.W.1    Chellappan, S.P.2    Horowitz, J.M.3    Nevins, J.R.4
  • 31
    • 0026802989 scopus 로고
    • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds, P.W., Mittnacht, S., Dulic, V., Arnold, A., Reeds, S.I. and Weinberg, R.A. (1992) Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell, 70, 993-1006.
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reeds, S.I.5    Weinberg, R.A.6
  • 32
    • 0029018708 scopus 로고
    • Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system
    • Hollenberg, S.M., Sternglanz, R., Cheng, P.F. and Weintraub, H. (1995) Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell. Biol., 15, 3813-3822.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3813-3822
    • Hollenberg, S.M.1    Sternglanz, R.2    Cheng, P.F.3    Weintraub, H.4
  • 33
    • 0027367144 scopus 로고
    • Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F
    • Ivey-Hoyle, M., Conroy, R., Huber, H.E., Goodhart, P.J., Oliff, A. and Heimbrook, D.C. (1993) Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol. Cell. Biol., 13, 7802-7812.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7802-7812
    • Ivey-Hoyle, M.1    Conroy, R.2    Huber, H.E.3    Goodhart, P.J.4    Oliff, A.5    Heimbrook, D.C.6
  • 34
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F-1 induces quiescent cells to enter S phase
    • Johnson, D.G., Schwarz, J.K., Cress, W.D. and Nevins, J.R. (1993) Expression of transcription factor E2F-1 induces quiescent cells to enter S phase. Nature, 365, 349-352.
    • (1993) Nature , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 35
    • 0028364529 scopus 로고
    • Autoregulatory control of E2F-1 expression in response to positive and negative regulators of cell cycle progression
    • Johnson, D.G., Ohtani, K. and Nevins, J.R. (1994) Autoregulatory control of E2F-1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev., 8, 1514-1525.
    • (1994) Genes Dev. , vol.8 , pp. 1514-1525
    • Johnson, D.G.1    Ohtani, K.2    Nevins, J.R.3
  • 37
    • 0028330795 scopus 로고
    • Detailed analysis of the basic domain of the E2F-1 transcription factor indicates that it is unique among bHLH proteins
    • Jordan, K.L., Haas, A.R., Logan, T.J. and Hall, D.J. (1994) Detailed analysis of the basic domain of the E2F-1 transcription factor indicates that it is unique among bHLH proteins. Oncogene, 9, 1177-1185.
    • (1994) Oncogene , vol.9 , pp. 1177-1185
    • Jordan, K.L.1    Haas, A.R.2    Logan, T.J.3    Hall, D.J.4
  • 38
    • 0026766083 scopus 로고
    • Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
    • Kaelin, W.G., Jr et al. (1992) Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell, 70, 351-364.
    • (1992) Cell , vol.70 , pp. 351-364
    • Kaelin Jr., W.G.1
  • 39
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
    • Kato, J., Matsushime, H., Hiebert, S.W., Ewen, M.E. and Sherr, C.J. (1993) Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev., 7, 331-342.
    • (1993) Genes Dev. , vol.7 , pp. 331-342
    • Kato, J.1    Matsushime, H.2    Hiebert, S.W.3    Ewen, M.E.4    Sherr, C.J.5
  • 40
    • 0022454147 scopus 로고
    • Identification of a cellular transcription factor involved in E1A transactivation
    • Kovesdi, I., Reichel, R. and Nevins, J.R. (1986) Identification of a cellular transcription factor involved in E1A transactivation. Cell, 45, 219-228.
    • (1986) Cell , vol.45 , pp. 219-228
    • Kovesdi, I.1    Reichel, R.2    Nevins, J.R.3
  • 41
    • 0027769885 scopus 로고
    • Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
    • Krek, W., Livingston, D.M. and Shirodkar, S. (1993) Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science, 262, 1557-1560.
    • (1993) Science , vol.262 , pp. 1557-1560
    • Krek, W.1    Livingston, D.M.2    Shirodkar, S.3
  • 42
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek, W., Ewen, M.E., Shirodkar, S., Arany, Z., Kaelin, W.G., Jr and Livingston, D.M. (1994) Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell, 78, 161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin Jr., W.G.5    Livingston, D.M.6
  • 43
    • 0028267869 scopus 로고
    • DRTF1/E2F: An expanding family of heterodimeric transcription factors implicated in cell-cycle control
    • La Thangue, N.B. (1994) DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem. Sci., 19, 108-114.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 108-114
    • La Thangue, N.B.1
  • 46
    • 0028801425 scopus 로고
    • The interferon-activatable gene 200 cluster: From structure toward function
    • Lengyel, P., Choubey, D., Li, S.-J. and Datta, B. (1995) The interferon-activatable gene 200 cluster: from structure toward function. Semin. Virol., 6, 203-213.
    • (1995) Semin. Virol. , vol.6 , pp. 203-213
    • Lengyel, P.1    Choubey, D.2    Li, S.-J.3    Datta, B.4
  • 48
    • 0027261370 scopus 로고
    • Interferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells
    • Melamed, D., Tiefenbrun, N., Yarden, A. and Kimchi, A. (1993) Interferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells. Mol. Cell. Biol., 13, 5255-5265.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5255-5265
    • Melamed, D.1    Tiefenbrun, N.2    Yarden, A.3    Kimchi, A.4
  • 49
    • 0029656068 scopus 로고    scopus 로고
    • The interferon-inducible p202 protein as a modulator of transcription: Inhibition of NF-κ-B, c-Fos, and c-Jun activities
    • Min, W., Ghosh, S. and Lengyel, P. (1996) The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-κ-B, c-Fos, and c-Jun activities. Mol. Cell. Biol., 16, 359-368.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 359-368
    • Min, W.1    Ghosh, S.2    Lengyel, P.3
  • 50
    • 0024506604 scopus 로고
    • Two different protein-protein interactions in oligomeric complexes of SV40 large T-antigen with the cellular oncoprotein p53
    • Montenarh, M. and Quaiser, A. (1989) Two different protein-protein interactions in oligomeric complexes of SV40 large T-antigen with the cellular oncoprotein p53. Oncogene, 4, 379-382.
    • (1989) Oncogene , vol.4 , pp. 379-382
    • Montenarh, M.1    Quaiser, A.2
  • 51
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
    • Nevins, J.R. (1992) E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science, 258, 424-429.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 52
    • 0029615315 scopus 로고
    • Physical and functional interactions between p53 and cell cycle cooperating transcription factors, E2F-1 and DP-1
    • O'Connor, D.J., Lam, E.W., Griffin, S., Zhong, S., Leighton, L.C., Burbidge, S.A. and Lu, X. (1995) Physical and functional interactions between p53 and cell cycle cooperating transcription factors, E2F-1 and DP-1. EMBO J., 14, 6184-6192.
    • (1995) EMBO J. , vol.14 , pp. 6184-6192
    • O'Connor, D.J.1    Lam, E.W.2    Griffin, S.3    Zhong, S.4    Leighton, L.C.5    Burbidge, S.A.6    Lu, X.7
  • 53
    • 0028787278 scopus 로고
    • A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF-1/E2F
    • Ormondroyd, E., De Luna, S. and La Thangue, N.B. (1995) A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF-1/E2F. Oncogene, 11, 1437-1446.
    • (1995) Oncogene , vol.11 , pp. 1437-1446
    • Ormondroyd, E.1    De Luna, S.2    La Thangue, N.B.3
  • 55
    • 0029612231 scopus 로고
    • A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
    • Sellers, W.R., Rodgers, J.W. and Kaelin, W.G., Jr (1995) A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc. Natl Acad. Sci. USA, 92, 11544-11548.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 11544-11548
    • Sellers, W.R.1    Rodgers, J.W.2    Kaelin Jr., W.G.3
  • 56
    • 0026739463 scopus 로고
    • The interferon system. A bird's eye view of its biochemistry
    • Sen, G.C. and Lengyel, P. (1992) The interferon system. A bird's eye view of its biochemistry. J. Biol. Chem., 267, 5017-5020.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5017-5020
    • Sen, G.C.1    Lengyel, P.2
  • 57
    • 0026484975 scopus 로고
    • Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: Identification of a gene with properties of the transcription factor E2F
    • Shan, B., Zhu, X., Chen, P.-L., Durfee, T., Yang, Y., Sharp, D. and Lee, W.H. (1992) Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol. Cell. Biol., 12, 5620-5631.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5620-5631
    • Shan, B.1    Zhu, X.2    Chen, P.-L.3    Durfee, T.4    Yang, Y.5    Sharp, D.6    Lee, W.H.7
  • 58
    • 17544366835 scopus 로고    scopus 로고
    • The N-terminal region of E2F-1 is required for transcriptional activation of a new class of target promoter
    • Shin, E.K., Tevosian, S.G. and Yee, Y.S. (1996) The N-terminal region of E2F-1 is required for transcriptional activation of a new class of target promoter. J. Biol. Chem., 271, 12261-12268.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12261-12268
    • Shin, E.K.1    Tevosian, S.G.2    Yee, Y.S.3
  • 59
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh, P., Wong, S.H. and Hong, W. (1994) Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J., 13, 3329-3338.
    • (1994) EMBO J. , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 60
    • 0028959057 scopus 로고
    • The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2
    • Smith, E.J. and Nevins, J.R. (1995) The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2. Mol. Cell. Biol., 15, 338-344.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 338-344
    • Smith, E.J.1    Nevins, J.R.2
  • 61
    • 0024651359 scopus 로고
    • Nuclear factor E2F mediates basic transcription and transactivation by E1A of the human MYC promoter
    • Thalmeier, K., Synovzik, H., Mertz, R., Winnacker, E.L. and Lipp, M. (1989) Nuclear factor E2F mediates basic transcription and transactivation by E1A of the human MYC promoter. Genes Dev., 3, 527-536.
    • (1989) Genes Dev. , vol.3 , pp. 527-536
    • Thalmeier, K.1    Synovzik, H.2    Mertz, R.3    Winnacker, E.L.4    Lipp, M.5
  • 62
    • 0027250250 scopus 로고
    • Mammalian Ras interacts directly with the serine/threonine kinase Raf
    • Vojtek, A.B., Hollenberg, S.M. and Cooper, J.A. (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell, 74, 205-214.
    • (1993) Cell , vol.74 , pp. 205-214
    • Vojtek, A.B.1    Hollenberg, S.M.2    Cooper, J.A.3
  • 63
    • 0023298866 scopus 로고
    • Single amino acid changes that render human IFN-α2 biologically active on mouse cells
    • Weber, H., Valenzuela, D., Lujber, G., Gubler, M. and Weissmann, C. (1987) Single amino acid changes that render human IFN-α2 biologically active on mouse cells. EMBO J., 6, 591-598.
    • (1987) EMBO J. , vol.6 , pp. 591-598
    • Weber, H.1    Valenzuela, D.2    Lujber, G.3    Gubler, M.4    Weissmann, C.5
  • 64
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R.A. (1995) The retinoblastoma protein and cell cycle control. Cell, 81, 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 65
    • 0029977751 scopus 로고    scopus 로고
    • E2F and cell proliferation: A word turned upside down
    • Weinberg, R.A. (1996) E2F and cell proliferation: a word turned upside down. Cell, 85, 457-459.
    • (1996) Cell , vol.85 , pp. 457-459
    • Weinberg, R.A.1
  • 66
    • 0026636908 scopus 로고
    • Retinoblastoma protein switches the E2F site from positive to negative element
    • Weintraub, S.J., Prater, C.A. and Dean, D.C. (1992) Retinoblastoma protein switches the E2F site from positive to negative element. Nature, 358, 259-261.
    • (1992) Nature , vol.358 , pp. 259-261
    • Weintraub, S.J.1    Prater, C.A.2    Dean, D.C.3
  • 67
    • 0028945789 scopus 로고
    • Multiple members of the E2F transcription factor family are the product of oncogenes
    • Xu, G., Livingston, D.M. and Krek, W. (1995) Multiple members of the E2F transcription factor family are the product of oncogenes. Proc. Natl Acad. Sci. USA, 92, 1357-1361.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 1357-1361
    • Xu, G.1    Livingston, D.M.2    Krek, W.3
  • 68
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
    • Xu, M., Sheppard, K.A., Peng, C.Y., Yee, A.S. and Piwnica-Worms, H. (1994) Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell. Biol., 14, 8420-8428.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8420-8428
    • Xu, M.1    Sheppard, K.A.2    Peng, C.Y.3    Yee, A.S.4    Piwnica-Worms, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.