-
1
-
-
70349442548
-
The first 30 years of p53: growing ever more complex
-
Levine, A. J. et al. (2009). The first 30 years of p53: growing ever more complex. Nat Rev Cancer 9(10): 749-758.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.10
, pp. 749-758
-
-
Levine, A.J.1
-
2
-
-
78650316134
-
p53 Research: the past thirty years and the next thirty years.
-
Lane, D. et al. (2010). p53 Research: the past thirty years and the next thirty years. Cold Spring Harb Perspect Biol 2(12): a000893.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.12
-
-
Lane, D.1
-
3
-
-
0024387728
-
Mutations in the p53 gene occur in diverse human tumour types
-
Nigro, J. M. et al. (1989). Mutations in the p53 gene occur in diverse human tumour types. Nature 342(6250): 705-708.
-
(1989)
Nature
, vol.342
, Issue.6250
, pp. 705-708
-
-
Nigro, J.M.1
-
4
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer, D. et al.(1993). Gain of function mutations in p53. Nat Genet 4(1): 42-46.
-
(1993)
Nat Genet
, vol.4
, Issue.1
, pp. 42-46
-
-
Dittmer, D.1
-
5
-
-
84862636275
-
Mutant p53: one name, many proteins
-
Freed-Pastor, W. A. and C. Prives (2012). Mutant p53: one name, many proteins. Genes Dev 26(12): 1268-1286.
-
(2012)
Genes Dev
, vol.26
, Issue.12
, pp. 1268-1286
-
-
Freed-Pastor, W.A.1
Prives, C.2
-
6
-
-
84856525447
-
Deconstructing p53 transcriptional networks in tumor suppression
-
Bieging, K. T. et al. (2012). Deconstructing p53 transcriptional networks in tumor suppression. Trends Cell Biol 22(2): 97-106.
-
(2012)
Trends Cell Biol
, vol.22
, Issue.2
, pp. 97-106
-
-
Bieging, K.T.1
-
7
-
-
84857342600
-
The p53 circuit board
-
Sullivan, K. D. et al. (2012). The p53 circuit board. Biochim Biophys Acta 1825(2): 229-244.
-
(2012)
Biochim Biophys Acta
, vol.1825
, Issue.2
, pp. 229-244
-
-
Sullivan, K.D.1
-
8
-
-
0021616838
-
UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
-
Maltzman, W. and L. Czyzyk (1984). UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol Cell Biol 4(9): 1689-1694.
-
(1984)
Mol Cell Biol
, vol.4
, Issue.9
, pp. 1689-1694
-
-
Maltzman, W.1
Czyzyk, L.2
-
9
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan, M. B. et al. (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71(4): 587-597.
-
(1992)
Cell
, vol.71
, Issue.4
, pp. 587-597
-
-
Kastan, M.B.1
-
10
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
-
Yonish-Rouach, E. et al. (1991). Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352(6333): 345-347.
-
(1991)
Nature
, vol.352
, Issue.6333
, pp. 345-347
-
-
Yonish-Rouach, E.1
-
11
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M., et al. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88(5): 593-602.
-
(1997)
Cell
, vol.88
, Issue.5
, pp. 593-602
-
-
Serrano, M.1
-
12
-
-
0032532558
-
Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs
-
Wang, Y. et al. (1998). Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs. Oncogene 17(15): 1923-1930.
-
(1998)
Oncogene
, vol.17
, Issue.15
, pp. 1923-1930
-
-
Wang, Y.1
-
13
-
-
84877574804
-
Another fork in the road--life or death decisions by the tumour suppressor p53
-
Carvajal, L. A. et al. (2013). Another fork in the road--life or death decisions by the tumour suppressor p53. EMBO Rep 14(5): 414-421.
-
(2013)
EMBO Rep
, vol.14
, Issue.5
, pp. 414-421
-
-
Carvajal, L.A.1
-
14
-
-
0027109075
-
Cancer. p53, guardian of the genome.
-
Lane, D. P. (1992). Cancer. p53, guardian of the genome. Nature 358(6381): 15-16.
-
(1992)
Nature
, vol.358
, Issue.6381
, pp. 15-16
-
-
Lane, D.P.1
-
15
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein, B. et al. (2000). Surfing the p53 network. Nature 408(6810): 307-310.
-
(2000)
Nature
, vol.408
, Issue.6810
, pp. 307-310
-
-
Vogelstein, B.1
-
16
-
-
84857443702
-
The p53 network: cellular and systemic DNA damage responses in aging and cancer
-
Reinhardt, H. C. et al. (2012). The p53 network: cellular and systemic DNA damage responses in aging and cancer. Trends Genet 28(3): 128-136.
-
(2012)
Trends Genet
, vol.28
, Issue.3
, pp. 128-136
-
-
Reinhardt, H.C.1
-
17
-
-
84873055344
-
MDM2, MDMX and p53 in oncogenesis and cancer therapy
-
Wade, M. et al. (2013). MDM2, MDMX and p53 in oncogenesis and cancer therapy. Nat Rev Cancer 13(2): 83-96.
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.2
, pp. 83-96
-
-
Wade, M.1
-
18
-
-
84871871425
-
It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53.
-
Love, I.M. et al. (2012). It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53. Genes Cancer 3(3-4):249-63.
-
(2012)
Genes Cancer
, vol.3
, Issue.3-4
, pp. 249-263
-
-
Love, I.M.1
-
19
-
-
84857725905
-
Post-translational modifications of p53 tumor suppressor: determinants of its functional targets
-
Taira, N. et al. (2012). Post-translational modifications of p53 tumor suppressor: determinants of its functional targets. Histol Histopathol 27(4): 437-443.
-
(2012)
Histol Histopathol
, vol.27
, Issue.4
, pp. 437-443
-
-
Taira, N.1
-
20
-
-
65349103899
-
Blinded by the Light: The Growing Complexity of p53
-
Vousden, K. H. et al. (2009). Blinded by the Light: The Growing Complexity of p53. Cell 137(3): 413-431.
-
(2009)
Cell
, vol.137
, Issue.3
, pp. 413-431
-
-
Vousden, K.H.1
-
21
-
-
84867142011
-
Regulation of lipid metabolism by p53 - fighting two villains with one sword
-
Goldstein, I. et al. (2012). Regulation of lipid metabolism by p53 - fighting two villains with one sword. Trends Endocrinol Metab 23(11): 567-575.
-
(2012)
Trends Endocrinol Metab
, vol.23
, Issue.11
, pp. 567-575
-
-
Goldstein, I.1
-
22
-
-
84864292987
-
Nuclear factor-kappaB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect
-
Johnson, R. F. et al. (2012). Nuclear factor-kappaB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect. Trends Biochem Sci 37(8): 317-324.
-
(2012)
Trends Biochem Sci
, vol.37
, Issue.8
, pp. 317-324
-
-
Johnson, R.F.1
-
23
-
-
84863244013
-
The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy
-
Shen, L., et al. (2012). The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy. Clin Cancer Res 18(6): 1561-1567.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.6
, pp. 1561-1567
-
-
Shen, L.1
-
24
-
-
84908217047
-
Tumor suppressor p53 and its mutants in cancer metabolism.
-
Liu, J. et al. (2013). Tumor suppressor p53 and its mutants in cancer metabolism. Cancer Lett.
-
(2013)
Cancer Lett.
-
-
Liu, J.1
-
25
-
-
84868249895
-
p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress
-
Dioufa, N. et al. (2012). p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress. Exp Biol Med (Maywood) 237(10): 1173-1180.
-
(2012)
Exp Biol Med (Maywood)
, vol.237
, Issue.10
, pp. 1173-1180
-
-
Dioufa, N.1
-
26
-
-
84875193929
-
p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress
-
Thomas, S. E. et al. (2013). p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress. J Biol Chem 288(11): 7606-7617.
-
(2013)
J Biol Chem
, vol.288
, Issue.11
, pp. 7606-7617
-
-
Thomas, S.E.1
-
27
-
-
77951243028
-
Autophagy regulation by p53
-
Maiuri, M. C. et al. (2010). Autophagy regulation by p53. Curr Opin Cell Biol 22(2): 181-185.
-
(2010)
Curr Opin Cell Biol
, vol.22
, Issue.2
, pp. 181-185
-
-
Maiuri, M.C.1
-
28
-
-
84884820821
-
Autophagy regulation and its role in cancer.
-
Lorin, S. et al. (2013). Autophagy regulation and its role in cancer. Semin Cancer Biol.
-
(2013)
Semin Cancer Biol.
-
-
Lorin, S.1
-
29
-
-
78649833334
-
p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation
-
Scherz-Shouval, R. et al. (2010). p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc Natl Acad Sci U S A 107(43): 18511-18516.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.43
, pp. 18511-18516
-
-
Scherz-Shouval, R.1
-
30
-
-
77956280751
-
p53 is balancing development, differentiation and de-differentiation to assure cancer prevention
-
Molchadsky, A. et al.(2010). p53 is balancing development, differentiation and de-differentiation to assure cancer prevention. Carcinogenesis 31(9): 1501-1508.
-
(2010)
Carcinogenesis
, vol.31
, Issue.9
, pp. 1501-1508
-
-
Molchadsky, A.1
-
31
-
-
84872463245
-
The TP53 fertility network.
-
Paskulin, D. et al. (2012). The TP53 fertility network. Genet Mol Biol 35(4 (suppl)): 939-946.
-
(2012)
Genet Mol Biol
, vol.35
, Issue.4 SUPPL
, pp. 939-946
-
-
Paskulin, D.1
-
32
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
Kawamura, T. et al.(2009). Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460(7259): 1140-1144.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1140-1144
-
-
Kawamura, T.1
-
33
-
-
11244344381
-
p53: traffic cop at the crossroads of DNA repair and recombination
-
Sengupta, S. et al. (2005). p53: traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol 6(1): 44-55.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.1
, pp. 44-55
-
-
Sengupta, S.1
-
34
-
-
77950346282
-
Immunity, inflammation, and cancer
-
Grivennikov, S. I. et al. (2010). Immunity, inflammation, and cancer. Cell 140(6): 883-899.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 883-899
-
-
Grivennikov, S.I.1
-
35
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Ben-Neriah, Y. et al. (2011). Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol 12(8): 715-723.
-
(2011)
Nat Immunol
, vol.12
, Issue.8
, pp. 715-723
-
-
Ben-Neriah, Y.1
-
36
-
-
0035321067
-
The evolution and genetics of innate immunity
-
Kimbrell, D. A. et al. (2001). The evolution and genetics of innate immunity. Nat Rev Genet 2(4): 256-267.
-
(2001)
Nat Rev Genet
, vol.2
, Issue.4
, pp. 256-267
-
-
Kimbrell, D.A.1
-
37
-
-
80053322451
-
Monocyte trafficking in acute and chronic inflammation
-
Ingersoll, M. A. et al. (2011). Monocyte trafficking in acute and chronic inflammation. Trends Immunol 32(10): 470-477.
-
(2011)
Trends Immunol
, vol.32
, Issue.10
, pp. 470-477
-
-
Ingersoll, M.A.1
-
38
-
-
84879413529
-
Resolution of inflammation: Mechanisms and opportunity for drug development
-
Alessandri, A. L. et al. (2013). Resolution of inflammation: Mechanisms and opportunity for drug development. Pharmacol Ther 139(2): 189-212.
-
(2013)
Pharmacol Ther
, vol.139
, Issue.2
, pp. 189-212
-
-
Alessandri, A.L.1
-
39
-
-
78649866460
-
Natural killer T cells: innate lymphocytes positioned as a bridge between acute and chronic inflammation?
-
Fox, L. et al. (2010). Natural killer T cells: innate lymphocytes positioned as a bridge between acute and chronic inflammation? Microbes Infect 12(14-15): 1125-1133.
-
(2010)
Microbes Infect
, vol.12
, Issue.14-15
, pp. 1125-1133
-
-
Fox, L.1
-
40
-
-
1342281227
-
Contribution of environmental factors to cancer risk.
-
Boffetta, P. et al.(2003). Contribution of environmental factors to cancer risk. Br Med Bull 68: 71-94.
-
(2003)
Br Med Bull
, vol.68
, pp. 71-94
-
-
Boffetta, P.1
-
41
-
-
84873412849
-
Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development
-
Azer, S. A. (2013). Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development. Eur J Gastroenterol Hepatol 25(3): 271-281.
-
(2013)
Eur J Gastroenterol Hepatol
, vol.25
, Issue.3
, pp. 271-281
-
-
Azer, S.A.1
-
42
-
-
84873541202
-
Helicobacter pylori is a risk factor for colonic neoplasms
-
Sonnenberg, A. et al. (2013). Helicobacter pylori is a risk factor for colonic neoplasms. Am J Gastroenterol 108(2): 208-215.
-
(2013)
Am J Gastroenterol
, vol.108
, Issue.2
, pp. 208-215
-
-
Sonnenberg, A.1
-
43
-
-
84888270793
-
Inflammation and liver tumorigenesis
-
Sun, B. et al. (2013). Inflammation and liver tumorigenesis. Front Med 7(2): 242-254.
-
(2013)
Front Med
, vol.7
, Issue.2
, pp. 242-254
-
-
Sun, B.1
-
44
-
-
0037446302
-
Nitric oxide in cancer and chemoprevention
-
Hofseth, L. J. et al.(2003). Nitric oxide in cancer and chemoprevention. Free Radic Biol Med 34(8): 955-968.
-
(2003)
Free Radic Biol Med
, vol.34
, Issue.8
, pp. 955-968
-
-
Hofseth, L.J.1
-
45
-
-
84864545633
-
Molecular link mechanisms between inflammation and cancer
-
Vendramini-Costa, D. B. et al. (2012). Molecular link mechanisms between inflammation and cancer. Curr Pharm Des 18(26): 3831-3852.
-
(2012)
Curr Pharm Des
, vol.18
, Issue.26
, pp. 3831-3852
-
-
Vendramini-Costa, D.B.1
-
46
-
-
0025981359
-
Insertion of specific bases during DNA synthesis past the oxidationdamaged base 8-oxodG
-
Shibutani, S. et al.(1991). Insertion of specific bases during DNA synthesis past the oxidationdamaged base 8-oxodG. Nature 349(6308): 431-434.
-
(1991)
Nature
, vol.349
, Issue.6308
, pp. 431-434
-
-
Shibutani, S.1
-
47
-
-
10444287596
-
Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis.
-
Bindra, R. S. et al. (2005). Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis. Mutat Res 569(1-2): 75-85.
-
(2005)
Mutat Res
, vol.569
, Issue.1-2
, pp. 75-85
-
-
Bindra, R.S.1
-
48
-
-
7944223098
-
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
-
Sparmann, A. et al. (2004). Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 6(5): 447-458.
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 447-458
-
-
Sparmann, A.1
-
49
-
-
34948852371
-
Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors
-
Soucek, L. et al. (2007). Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors. Nat Med 13(10): 1211-1218.
-
(2007)
Nat Med
, vol.13
, Issue.10
, pp. 1211-1218
-
-
Soucek, L.1
-
50
-
-
84886819170
-
The fine balance of chemokines during disease: trafficking, inflammation, and homeostasis.
-
Cardona, S. M. et al.(2013). The fine balance of chemokines during disease: trafficking, inflammation, and homeostasis. Methods Mol Biol 1013: 1-16.
-
(2013)
Methods Mol Biol
, vol.1013
, pp. 1-16
-
-
Cardona, S.M.1
-
51
-
-
79958710624
-
Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence
-
Guerra, C. et al. (2011). Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. Cancer Cell 19(6): 728-739.
-
(2011)
Cancer Cell
, vol.19
, Issue.6
, pp. 728-739
-
-
Guerra, C.1
-
52
-
-
84859710888
-
An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice
-
Daniluk, J. et al. (2012). An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest 122(4): 1519-1528.
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1519-1528
-
-
Daniluk, J.1
-
53
-
-
84867861575
-
Involvement of pelvic inflammation-related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis
-
Fuseya, C. et al. (2012). Involvement of pelvic inflammation-related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis. Hum Pathol 43(11): 1964-1972.
-
(2012)
Hum Pathol
, vol.43
, Issue.11
, pp. 1964-1972
-
-
Fuseya, C.1
-
54
-
-
0034282793
-
Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1
-
Fleisher, A. S. et al.(2000). Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res 60(17): 4864-4868.
-
(2000)
Cancer Res
, vol.60
, Issue.17
, pp. 4864-4868
-
-
Fleisher, A.S.1
-
55
-
-
22344434975
-
Molecular phenotype of inflammatory bowel disease-associated neoplasms with microsatellite instability
-
Schulmann, K. et al.(2005). Molecular phenotype of inflammatory bowel disease-associated neoplasms with microsatellite instability. Gastroenterology 129(1): 74-85.
-
(2005)
Gastroenterology
, vol.129
, Issue.1
, pp. 74-85
-
-
Schulmann, K.1
-
56
-
-
33947158749
-
Viral oncoproteins target the DNA methyltransferases
-
Burgers, W. A. et al.(2007). Viral oncoproteins target the DNA methyltransferases. Oncogene 26(11): 1650-1655.
-
(2007)
Oncogene
, vol.26
, Issue.11
, pp. 1650-1655
-
-
Burgers, W.A.1
-
57
-
-
23844472366
-
Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas
-
Hirohashi
-
Peng, D. F. et al. Hirohashi (2005). Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas. Cancer Sci 96(7): 403-408.
-
(2005)
Cancer Sci
, vol.96
, Issue.7
, pp. 403-408
-
-
Peng, D.F.1
-
58
-
-
0030830914
-
DNA hypermethylation at the D17S5 locus in non-small cell lung cancers: its association with smoking history
-
Eguchi, K. et al. (1997). DNA hypermethylation at the D17S5 locus in non-small cell lung cancers: its association with smoking history. Cancer Res 57(21): 4913-4915.
-
(1997)
Cancer Res
, vol.57
, Issue.21
, pp. 4913-4915
-
-
Eguchi, K.1
-
59
-
-
84869006006
-
Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.
-
Mishra, A. et al. (2012). Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation. Cancer Cell 22(5): 645- 655.
-
(2012)
Cancer Cell
, vol.22
, Issue.5
, pp. 645-655
-
-
Mishra, A.1
-
60
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene, B. et al. (2013). Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13(2): 97-110.
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.2
, pp. 97-110
-
-
De Craene, B.1
-
61
-
-
0029671316
-
TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice
-
Maeda, H. et al. (1996). TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice. J Immunol 156(1): 73-78.
-
(1996)
J Immunol
, vol.156
, Issue.1
, pp. 73-78
-
-
Maeda, H.1
-
62
-
-
66349099293
-
Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated
-
Torroella-Kouri, M. et al.(2009). Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated. Cancer Res 69(11): 4800-4809.
-
(2009)
Cancer Res
, vol.69
, Issue.11
, pp. 4800-4809
-
-
Torroella-Kouri, M.1
-
63
-
-
33646255924
-
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
-
Wislez, M., N. Fujimoto, J. G. Izzo, A. E. Hanna, D. D. Cody, R. R. Langley, H. Tang, M. D. Burdick, M. Sato, J. D. Minna, L. Mao, I. Wistuba, R. M. Strieter and J. M. Kurie (2006). "High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras." Cancer Res 66(8): 4198-4207.
-
(2006)
Cancer Res
, vol.66
, Issue.8
, pp. 4198-4207
-
-
Wislez, M.1
Fujimoto, N.2
Izzo, J.G.3
Hanna, A.E.4
Cody, D.D.5
Langley, R.R.6
Tang, H.7
Burdick, M.D.8
Sato, M.9
Minna, J.D.10
Mao, L.11
Wistuba, I.12
Strieter, R.M.13
Kurie, J.M.14
-
64
-
-
34447506658
-
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.
-
Ancrile, B., K. H. Lim and C. M. Counter (2007). "Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis." Genes Dev 21(14): 1714-1719.
-
(2007)
Genes Dev
, vol.21
, Issue.14
, pp. 1714-1719
-
-
Ancrile, B.1
Lim, K.H.2
Counter, C.M.3
-
65
-
-
84872598312
-
Cancer-related inflammation.
-
Candido, J. et al. (2013). Cancer-related inflammation. J Clin Immunol 33 Suppl 1: S79-84.
-
(2013)
J Clin Immunol
, vol.33
, Issue.SUPPL 1
-
-
Candido, J.1
-
66
-
-
0036184190
-
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
-
Meng, T. C. et al. (2002). Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol Cell 9(2): 387-399.
-
(2002)
Mol Cell
, vol.9
, Issue.2
, pp. 387-399
-
-
Meng, T.C.1
-
67
-
-
61649086403
-
Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.
-
Nowsheen, S. et al.(2009). Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues. Mutat Res 674(1-2): 131-136.
-
(2009)
Mutat Res
, vol.674
, Issue.1-2
, pp. 131-136
-
-
Nowsheen, S.1
-
68
-
-
33745489431
-
Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
-
Kawanishi, S. et al. (2006). Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem 387(4): 365-372.
-
(2006)
Biol Chem
, vol.387
, Issue.4
, pp. 365-372
-
-
Kawanishi, S.1
-
69
-
-
77956233017
-
The role of iNOS-mediated DNA damage in infection- and asbestosinduced carcinogenesis.
-
Hiraku, Y. et al.(2010). The role of iNOS-mediated DNA damage in infection- and asbestosinduced carcinogenesis. Ann N Y Acad Sci 1203: 15-22.
-
(2010)
Ann N Y Acad Sci
, vol.1203
, pp. 15-22
-
-
Hiraku, Y.1
-
70
-
-
0034089566
-
Host cyclooxygenase-2 modulates carcinoma growth
-
Williams, C. S. et al.(2000). Host cyclooxygenase-2 modulates carcinoma growth. J Clin Invest 105(11): 1589-1594.
-
(2000)
J Clin Invest
, vol.105
, Issue.11
, pp. 1589-1594
-
-
Williams, C.S.1
-
71
-
-
34147220392
-
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
-
Gupta, G. P. et al. (2007). Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 446(7137): 765-770.
-
(2007)
Nature
, vol.446
, Issue.7137
, pp. 765-770
-
-
Gupta, G.P.1
-
72
-
-
34547121441
-
Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells
-
Qualtrough, D. et al.(2007). Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells. Int J Cancer 121(4): 734-740.
-
(2007)
Int J Cancer
, vol.121
, Issue.4
, pp. 734-740
-
-
Qualtrough, D.1
-
73
-
-
84877004454
-
Cytokine patterns in patients with cancer: a systematic review.
-
Lippitz, B. E. (2013). Cytokine patterns in patients with cancer: a systematic review. Lancet Oncol 14(6): e218-228.
-
(2013)
Lancet Oncol
, vol.14
, Issue.6
-
-
Lippitz, B.E.1
-
74
-
-
78649982907
-
The dynamic roles of TGF-beta in cancer
-
Meulmeester, E. et al.(2011). The dynamic roles of TGF-beta in cancer. J Pathol 223(2): 205-218.
-
(2011)
J Pathol
, vol.223
, Issue.2
, pp. 205-218
-
-
Meulmeester, E.1
-
75
-
-
74049140048
-
Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways
-
Schetter, A. J. et al.(2010). Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 31(1): 37-49.
-
(2010)
Carcinogenesis
, vol.31
, Issue.1
, pp. 37-49
-
-
Schetter, A.J.1
-
76
-
-
84875769575
-
Regulation of immune responses and tolerance: the microRNA perspective
-
Chen, C. Z. et al.(2013). Regulation of immune responses and tolerance: the microRNA perspective. Immunol Rev 253(1): 112-128.
-
(2013)
Immunol Rev
, vol.253
, Issue.1
, pp. 112-128
-
-
Chen, C.Z.1
-
77
-
-
84905710402
-
The pivotal role of microRNA-155 in the control of cancer.
-
Chen, Z. et al.(2013). The pivotal role of microRNA-155 in the control of cancer. J Cell Physiol.
-
(2013)
J Cell Physiol.
-
-
Chen, Z.1
-
78
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
Iliopoulos, D. et al. (2010). STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell 39(4): 493-506.
-
(2010)
Mol Cell
, vol.39
, Issue.4
, pp. 493-506
-
-
Iliopoulos, D.1
-
79
-
-
77956339881
-
OncomiR addiction in an in vivo model of microRNA-21-induced pre- B-cell lymphoma
-
Medina, P. P. et al. (2010). OncomiR addiction in an in vivo model of microRNA-21-induced pre- B-cell lymphoma. Nature 467(7311): 86-90.
-
(2010)
Nature
, vol.467
, Issue.7311
, pp. 86-90
-
-
Medina, P.P.1
-
80
-
-
84879644246
-
MiR-21/Smad 7 signaling determines TGF-beta1-induced CAF formation.
-
Li, Q. et al. (2013). MiR-21/Smad 7 signaling determines TGF-beta1-induced CAF formation. Sci Rep 3: 2038.
-
(2013)
Sci Rep
, vol.3
, pp. 2038
-
-
Li, Q.1
-
81
-
-
28544431948
-
The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.
-
Staib, F. et al.(2005). The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress. Cancer Res 65(22): 10255- 10264.
-
(2005)
Cancer Res
, vol.65
, Issue.22
, pp. 10255-10264
-
-
Staib, F.1
-
82
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak, K. et al.(1997). A model for p53-induced apoptosis. Nature 389(6648): 300-305.
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 300-305
-
-
Polyak, K.1
-
83
-
-
0033597221
-
Transcriptional activation of the human glutathione peroxidase promoter by p53
-
Tan, M. et al.(1999). Transcriptional activation of the human glutathione peroxidase promoter by p53. J Biol Chem 274(17): 12061-12066.
-
(1999)
J Biol Chem
, vol.274
, Issue.17
, pp. 12061-12066
-
-
Tan, M.1
-
84
-
-
2142815107
-
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
-
Budanov, A. V. et al. (2004). Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science 304(5670): 596-600.
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 596-600
-
-
Budanov, A.V.1
-
85
-
-
1942520427
-
Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses
-
Yoon, K. A. et al. (2004). Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses. J Hum Genet 49(3): 134-140.
-
(2004)
J Hum Genet
, vol.49
, Issue.3
, pp. 134-140
-
-
Yoon, K.A.1
-
86
-
-
0037422535
-
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
-
Hofseth, L. J. et al.(2003). Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc Natl Acad Sci U S A 100(1): 143-148.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.1
, pp. 143-148
-
-
Hofseth, L.J.1
-
87
-
-
9244232804
-
Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.
-
Forrester, K. et al.(1996). "Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53." Proc Natl Acad Sci U S A 93(6): 2442-2447.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.6
, pp. 2442-2447
-
-
Forrester, K.1
-
88
-
-
0034685015
-
Nitric oxide nitrates tyrosine residues of tumor-suppressor p53 protein in MCF-7 cells
-
Chazotte-Aubert, L. et al.(2000). Nitric oxide nitrates tyrosine residues of tumor-suppressor p53 protein in MCF-7 cells. Biochem Biophys Res Commun 267(2): 609-613.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, Issue.2
, pp. 609-613
-
-
Chazotte-Aubert, L.1
-
89
-
-
0036845260
-
P53-mediated induction of Cox-2 counteracts p53- or genotoxic stressinduced apoptosis.
-
Han, J.A. et al. (2002) P53-mediated induction of Cox-2 counteracts p53- or genotoxic stressinduced apoptosis. EMBO J. 21(21):5635-44.
-
(2002)
EMBO J.
, vol.21
, Issue.21
, pp. 5635-5644
-
-
Han, J.A.1
-
90
-
-
84881538023
-
Changes in COX-2 and oxidative damage factors during differentiation of human mesenchymal stem cells to hepatocyte-like cells is associated with downregulation of p53 gene.
-
Khajeniazi, S. et al.(2013). Changes in COX-2 and oxidative damage factors during differentiation of human mesenchymal stem cells to hepatocyte-like cells is associated with downregulation of p53 gene. Biol Chem.
-
(2013)
Biol Chem.
-
-
Khajeniazi, S.1
-
91
-
-
0036121416
-
Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas
-
Niki, T. et al. (2002). Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas. Am J Pathol 160(3): 1129-1141.
-
(2002)
Am J Pathol
, vol.160
, Issue.3
, pp. 1129-1141
-
-
Niki, T.1
-
92
-
-
84934437871
-
The p53/microRNA network in cancer: experimental and bioinformatics approaches.
-
Hunten, S. et al. (2013). The p53/microRNA network in cancer: experimental and bioinformatics approaches. Adv Exp Med Biol 774: 77-101.
-
(2013)
Adv Exp Med Biol
, vol.774
, pp. 77-101
-
-
Hunten, S.1
-
93
-
-
84868254278
-
miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma
-
Kasinski, A. L. (2012). miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Cancer Res 72(21): 5576-5587.
-
(2012)
Cancer Res
, vol.72
, Issue.21
, pp. 5576-5587
-
-
Kasinski, A.L.1
-
94
-
-
79952086863
-
Dual Role of p53 in Innate Antiviral Immunity
-
Rivas, C. et al.(2010). Dual Role of p53 in Innate Antiviral Immunity. Viruses 2(1): 298-313.
-
(2010)
Viruses
, vol.2
, Issue.1
, pp. 298-313
-
-
Rivas, C.1
-
95
-
-
18144401357
-
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation
-
Tomso, D. J. et al. (2005). Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation. Proc Natl Acad Sci U S A 102(18): 6431-6436.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.18
, pp. 6431-6436
-
-
Tomso, D.J.1
-
96
-
-
79953765885
-
The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.
-
Menendez, D. et al. (2011). The Toll-like receptor gene family is integrated into human DNA damage and p53 networks. PLoS Genet 7(3): e1001360.
-
(2011)
PLoS Genet
, vol.7
, Issue.3
-
-
Menendez, D.1
-
97
-
-
84879577081
-
p53 Integrates host defense and cell fate during bacterial pneumonia
-
Madenspacher, J. H. et al (2013). p53 Integrates host defense and cell fate during bacterial pneumonia. J Exp Med 210(5): 891-904.
-
(2013)
J Exp Med
, vol.210
, Issue.5
, pp. 891-904
-
-
Madenspacher, J.H.1
-
98
-
-
0036142706
-
Regulation of joint destruction and inflammation by p53 in collageninduced arthritis
-
Yamanishi, Y. et al. (2002). Regulation of joint destruction and inflammation by p53 in collageninduced arthritis. Am J Pathol 160(1): 123-130.
-
(2002)
Am J Pathol
, vol.160
, Issue.1
, pp. 123-130
-
-
Yamanishi, Y.1
-
99
-
-
17844392396
-
Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function
-
Zheng, S. J. et al.(2005). Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function. Diabetes 54(5): 1423-1428.
-
(2005)
Diabetes
, vol.54
, Issue.5
, pp. 1423-1428
-
-
Zheng, S.J.1
-
100
-
-
84875700814
-
p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice
-
Park, J. S. et al. (2013). p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice. Arthritis Rheum 65(4): 949-959.
-
(2013)
Arthritis Rheum
, vol.65
, Issue.4
, pp. 949-959
-
-
Park, J.S.1
-
101
-
-
80051709190
-
Inflammation and p53: A Tale of Two Stresses
-
Gudkov, A. V. et al. (2011). Inflammation and p53: A Tale of Two Stresses. Genes Cancer 2(4): 503-516.
-
(2011)
Genes Cancer
, vol.2
, Issue.4
, pp. 503-516
-
-
Gudkov, A.V.1
-
102
-
-
84873638532
-
Aging, cellular senescence, and cancer.
-
Campisi, J. (2013). Aging, cellular senescence, and cancer. Annu Rev Physiol 75: 685-705.
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 685-705
-
-
Campisi, J.1
-
103
-
-
84871955225
-
Interactions between the tumor suppressor p53 and immune responses
-
Menendez, D. et al. (2013). Interactions between the tumor suppressor p53 and immune responses. Curr Opin Oncol 25(1): 85-92.
-
(2013)
Curr Opin Oncol
, vol.25
, Issue.1
, pp. 85-92
-
-
Menendez, D.1
-
104
-
-
84886794616
-
Senescence and aging: the critical roles of p53
-
Rufini, A. et al. (2013). Senescence and aging: the critical roles of p53. Oncogene 32(43): 5129-5143.
-
(2013)
Oncogene
, vol.32
, Issue.43
, pp. 5129-5143
-
-
Rufini, A.1
-
105
-
-
84881526073
-
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism
-
Pribluda, A. et al. (2013). A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism. Cancer Cell 24(2): 242-256.
-
(2013)
Cancer Cell
, vol.24
, Issue.2
, pp. 242-256
-
-
Pribluda, A.1
-
106
-
-
84861973567
-
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
-
Li, T. et al.(2012). Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 149(6): 1269-1283.
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1269-1283
-
-
Li, T.1
-
107
-
-
77957850069
-
p53 and NF-kappaB: different strategies for responding to stress lead to a functional antagonism
-
Ak, P. et al. (2010). p53 and NF-kappaB: different strategies for responding to stress lead to a functional antagonism. FASEB J 24(10): 3643-3652.
-
(2010)
FASEB J
, vol.24
, Issue.10
, pp. 3643-3652
-
-
Ak, P.1
-
108
-
-
43049139541
-
p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
-
Kawauchi, K. et al. (2008). p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation. Nat Cell Biol 10(5): 611-618.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.5
, pp. 611-618
-
-
Kawauchi, K.1
-
109
-
-
0034616639
-
p300/CBP-dependent and -independent transcriptional interference between NF-kappaB RelA and p53
-
Ikeda, A. et al. (2000). p300/CBP-dependent and -independent transcriptional interference between NF-kappaB RelA and p53. Biochem Biophys Res Commun 272(2): 375-379.
-
(2000)
Biochem Biophys Res Commun
, vol.272
, Issue.2
, pp. 375-379
-
-
Ikeda, A.1
-
110
-
-
62449257012
-
Phosphorylation of p53 by IkappaB kinase 2 promotes its degradation by beta-TrCP
-
Xia, Y. et al. (2009). Phosphorylation of p53 by IkappaB kinase 2 promotes its degradation by beta-TrCP. Proc Natl Acad Sci U S A 106(8): 2629-2634.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.8
, pp. 2629-2634
-
-
Xia, Y.1
-
111
-
-
0033593217
-
CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling.
-
Wadgaonkar, R. et al. (1999). CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling. J Biol Chem. 274(4):1879-82.
-
(1999)
J Biol Chem.
, vol.274
, Issue.4
, pp. 1879-1882
-
-
Wadgaonkar, R.1
-
112
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B
-
Campbell, K. J. et al. (2004). Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol Cell 13(6): 853-865.
-
(2004)
Mol Cell
, vol.13
, Issue.6
, pp. 853-865
-
-
Campbell, K.J.1
-
113
-
-
33646006734
-
Signals from within: the DNA-damage-induced NF-kappaB response
-
Janssens, S. et al.(2006). Signals from within: the DNA-damage-induced NF-kappaB response. Cell Death Differ 13(5): 773-784.
-
(2006)
Cell Death Differ
, vol.13
, Issue.5
, pp. 773-784
-
-
Janssens, S.1
-
114
-
-
33749868608
-
Differential effects of NF-kappaB on apoptosis induced by DNAdamaging agents: the type of DNA damage determines the final outcome
-
Strozyk, E. et al.(2006). Differential effects of NF-kappaB on apoptosis induced by DNAdamaging agents: the type of DNA damage determines the final outcome. Oncogene 25(47): 6239-6251.
-
(2006)
Oncogene
, vol.25
, Issue.47
, pp. 6239-6251
-
-
Strozyk, E.1
-
115
-
-
0029814061
-
Anti-apoptotic activity of low levels of wild-type p53
-
Lassus, P. et al. (1996). Anti-apoptotic activity of low levels of wild-type p53. EMBO J 15(17): 4566-4573.
-
(1996)
EMBO J
, vol.15
, Issue.17
, pp. 4566-4573
-
-
Lassus, P.1
-
116
-
-
44049092395
-
The dark side of a tumor suppressor: anti-apoptotic p53
-
Janicke, R. U. et al. (2008). The dark side of a tumor suppressor: anti-apoptotic p53. Cell Death Differ 15(6): 959-976.
-
(2008)
Cell Death Differ
, vol.15
, Issue.6
, pp. 959-976
-
-
Janicke, R.U.1
-
117
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
Ryan, K. M. et al. (2000). Role of NF-kappaB in p53-mediated programmed cell death. Nature 404(6780): 892-897.
-
(2000)
Nature
, vol.404
, Issue.6780
, pp. 892-897
-
-
Ryan, K.M.1
-
118
-
-
0033812557
-
Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis
-
Lin, Y. et al. (2000). Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nat Genet 26(1): 122-127.
-
(2000)
Nat Genet
, vol.26
, Issue.1
, pp. 122-127
-
-
Lin, Y.1
-
119
-
-
33845768987
-
Integrating cell-signalling pathways with NF-kappaB and IKK function
-
Perkins, N. D. (2007). Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 8(1): 49-62.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.1
, pp. 49-62
-
-
Perkins, N.D.1
-
120
-
-
23944482310
-
Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis.
-
Elkon, R. et al. (2005). Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis. Genome Biol 6(5): R43.
-
(2005)
Genome Biol
, vol.6
, Issue.5
-
-
Elkon, R.1
-
121
-
-
80054789761
-
Control of the senescence-associated secretory phenotype by NFkappaB promotes senescence and enhances chemosensitivity
-
Chien, Y. et al. (2011). Control of the senescence-associated secretory phenotype by NFkappaB promotes senescence and enhances chemosensitivity. Genes Dev 25(20): 2125-2136.
-
(2011)
Genes Dev
, vol.25
, Issue.20
, pp. 2125-2136
-
-
Chien, Y.1
-
122
-
-
28944447430
-
PIDD mediates NF-kappaB activation in response to DNA damage
-
Janssens, S. et al. (2005). PIDD mediates NF-kappaB activation in response to DNA damage. Cell 123(6): 1079-1092.
-
(2005)
Cell
, vol.123
, Issue.6
, pp. 1079-1092
-
-
Janssens, S.1
-
123
-
-
79952275158
-
The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation
-
Frank, A. K. et al. (2011). The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation. Mol Cell Biol 31(6): 1201-1213.
-
(2011)
Mol Cell Biol
, vol.31
, Issue.6
, pp. 1201-1213
-
-
Frank, A.K.1
-
124
-
-
24344448786
-
p53 isoforms can regulate p53 transcriptional activity
-
Bourdon, J. C. et al. (2005). p53 isoforms can regulate p53 transcriptional activity. Genes Dev 19(18): 2122-2137.
-
(2005)
Genes Dev
, vol.19
, Issue.18
, pp. 2122-2137
-
-
Bourdon, J.C.1
-
125
-
-
84890942102
-
Uncovering the role of p53 splice variants in human malignancy: a clinical perspective.
-
Surget, S. et al. (2013). Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. Onco Targets Ther 7: 57-68.
-
(2013)
Onco Targets Ther
, vol.7
, pp. 57-68
-
-
Surget, S.1
-
126
-
-
81155139688
-
Biological functions of p53 isoforms through evolution: lessons from animal and cellular models
-
Marcel, V. et al. (2011). Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death Differ 18(12): 1815-1824.
-
(2011)
Cell Death Differ
, vol.18
, Issue.12
, pp. 1815-1824
-
-
Marcel, V.1
-
127
-
-
84890942102
-
Uncovering the role of p53 splice variants in human malignancy: a clinical perspective.
-
Surget, S. et al. (2013). Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. Onco Targets Ther. 7:57-68
-
(2013)
Onco Targets Ther.
, vol.7
, pp. 57-68
-
-
Surget, S.1
-
128
-
-
79955952990
-
Hyperproliferation, cancer, and inflammation in mice expressing a Delta133p53-like isoform
-
Slatter, T. et al. (2011). Hyperproliferation, cancer, and inflammation in mice expressing a Delta133p53-like isoform. Blood 117(19): 5166-5177.
-
(2011)
Blood
, vol.117
, Issue.19
, pp. 5166-5177
-
-
Slatter, T.1
-
129
-
-
84857218196
-
Does Delta133p53 isoform trigger inflammation and autoimmunity?
-
Campbell, H. G. et al. (2012). Does Delta133p53 isoform trigger inflammation and autoimmunity? Cell Cycle 11(3): 446-450.
-
(2012)
Cell Cycle
, vol.11
, Issue.3
, pp. 446-450
-
-
Campbell, H.G.1
-
130
-
-
84866540647
-
Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses.
-
Wei, J. et al. (2012). Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses. Proc Natl Acad Sci U S A 109(38): E2543-2550.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.38
-
-
Wei, J.1
-
131
-
-
84861664029
-
p63/p73 in the control of cell cycle and cell death
-
Allocati, N. et al. (2012). p63/p73 in the control of cell cycle and cell death. Exp Cell Res 318(11): 1285-1290.
-
(2012)
Exp Cell Res
, vol.318
, Issue.11
, pp. 1285-1290
-
-
Allocati, N.1
-
132
-
-
78650873252
-
p63 and p73, the ancestors of p53.
-
Dotsch, V. et al.(2010). p63 and p73, the ancestors of p53. Cold Spring Harb Perspect Biol 2(9): a004887.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.9
-
-
Dotsch, V.1
-
133
-
-
17544363909
-
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
-
Yang, A. et al. (2000). p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature 404(6773): 99-103.
-
(2000)
Nature
, vol.404
, Issue.6773
, pp. 99-103
-
-
Yang, A.1
-
134
-
-
10744232289
-
Identification of the interleukin 4 receptor alpha gene as a direct target for p73
-
Sasaki, Y. et al. (2003). Identification of the interleukin 4 receptor alpha gene as a direct target for p73. Cancer Res 63(23): 8145-8152.
-
(2003)
Cancer Res
, vol.63
, Issue.23
, pp. 8145-8152
-
-
Sasaki, Y.1
-
135
-
-
84878040812
-
Proinflammatory cytokines and bile acids upregulate DeltaNp73 protein, an inhibitor of p53 and p73 tumor suppressors.
-
Zaika, E. et al. (2013). Proinflammatory cytokines and bile acids upregulate DeltaNp73 protein, an inhibitor of p53 and p73 tumor suppressors. PLoS One 8(5): e64306.
-
(2013)
PLoS One
, vol.8
, Issue.5
-
-
Zaika, E.1
-
136
-
-
76749100683
-
Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta
-
Chatterjee, A. et al. (2010). Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta. Cancer Res 70(4): 1419-1429.
-
(2010)
Cancer Res
, vol.70
, Issue.4
, pp. 1419-1429
-
-
Chatterjee, A.1
-
137
-
-
48549102989
-
The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth
-
King, K. E. et al.(2008). The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth. Cancer Res 68(13): 5122-5131.
-
(2008)
Cancer Res
, vol.68
, Issue.13
, pp. 5122-5131
-
-
King, K.E.1
-
138
-
-
80155126633
-
TNF-alpha promotes c-REL/DeltaNp63alpha interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer
-
Lu, H. et al. (2011). TNF-alpha promotes c-REL/DeltaNp63alpha interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer. Cancer Res 71(21): 6867-6877.
-
(2011)
Cancer Res
, vol.71
, Issue.21
, pp. 6867-6877
-
-
Lu, H.1
-
139
-
-
77950521214
-
Mutant p53 gain-of-function in cancer.
-
Oren, M. et al. (2010). Mutant p53 gain-of-function in cancer. Cold Spring Harb Perspect Biol 2(2): a001107.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.2
-
-
Oren, M.1
-
140
-
-
84871830221
-
p53 mutations in cancer
-
Muller, P. A. et al. (2013). p53 mutations in cancer. Nat Cell Biol 15(1): 2-8.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.1
, pp. 2-8
-
-
Muller, P.A.1
-
141
-
-
9244260573
-
Gene expression in the lung of p53 mutant mice exposed to cigarette smoke
-
Izzotti, A. et al. (2004). Gene expression in the lung of p53 mutant mice exposed to cigarette smoke. Cancer Res 64(23): 8566-8572.
-
(2004)
Cancer Res
, vol.64
, Issue.23
, pp. 8566-8572
-
-
Izzotti, A.1
-
142
-
-
84863045363
-
Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration
-
Yeudall, W. A. et al. (2012). Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration. Carcinogenesis 33(2): 442-451.
-
(2012)
Carcinogenesis
, vol.33
, Issue.2
, pp. 442-451
-
-
Yeudall, W.A.1
-
143
-
-
27644529786
-
Tumor-derived p53 mutants induce NF-kappaB2 gene expression
-
Scian, M. J. et al. (2005). Tumor-derived p53 mutants induce NF-kappaB2 gene expression. Mol Cell Biol 25(22): 10097-10110.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.22
, pp. 10097-10110
-
-
Scian, M.J.1
-
144
-
-
34047263449
-
Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells
-
Weisz, L. et al. (2007). Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells. Cancer Res 67(6): 2396-2401.
-
(2007)
Cancer Res
, vol.67
, Issue.6
, pp. 2396-2401
-
-
Weisz, L.1
-
145
-
-
77952424136
-
Cross talk between stimulated NF-kappaB and the tumor suppressor p53
-
Schneider, G. et al. (2010). Cross talk between stimulated NF-kappaB and the tumor suppressor p53. Oncogene 29(19): 2795-2806.
-
(2010)
Oncogene
, vol.29
, Issue.19
, pp. 2795-2806
-
-
Schneider, G.1
-
146
-
-
84877823153
-
Mutant p53 prolongs NF-kappaB activation and promotes chronic inflammation and inflammation-associated colorectal cancer
-
Cooks, T. et al.(2013). Mutant p53 prolongs NF-kappaB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. Cancer Cell 23(5): 634-646.
-
(2013)
Cancer Cell
, vol.23
, Issue.5
, pp. 634-646
-
-
Cooks, T.1
-
147
-
-
0346606862
-
Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease.
-
Hussain, S. P. et al. (2000). Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res 60(13): 3333- 3337.
-
(2000)
Cancer Res
, vol.60
, Issue.13
, pp. 3333-3337
-
-
Hussain, S.P.1
-
148
-
-
79955564023
-
Intestinal inflammation and cancer
-
Ullman, T. A. et al. (2011). Intestinal inflammation and cancer. Gastroenterology 140(6): 1807-1816.
-
(2011)
Gastroenterology
, vol.140
, Issue.6
, pp. 1807-1816
-
-
Ullman, T.A.1
-
149
-
-
34147180434
-
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
-
Matsumoto, Y. et al. (2007). Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med 13(4): 470-476.
-
(2007)
Nat Med
, vol.13
, Issue.4
, pp. 470-476
-
-
Matsumoto, Y.1
-
150
-
-
84865145772
-
The human TLR innate immune gene family is differentially influenced by DNA stress and p53 status in cancer cells
-
Shatz, M. et al. (2012). The human TLR innate immune gene family is differentially influenced by DNA stress and p53 status in cancer cells. Cancer Res 72(16): 3948-3957.
-
(2012)
Cancer Res
, vol.72
, Issue.16
, pp. 3948-3957
-
-
Shatz, M.1
-
151
-
-
33845348208
-
p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts
-
Moskovits, N. et al. (2006). p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts. Cancer Res 66(22): 10671-10676.
-
(2006)
Cancer Res
, vol.66
, Issue.22
, pp. 10671-10676
-
-
Moskovits, N.1
-
152
-
-
16444363001
-
Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis
-
Kiaris, H. et al. (2005). Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis. Cancer Res 65(5): 1627-1630.
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 1627-1630
-
-
Kiaris, H.1
-
153
-
-
78649930457
-
p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner
-
Addadi, Y. et al.(2010). p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner. Cancer Res 70(23): 9650-9658.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9650-9658
-
-
Addadi, Y.1
-
154
-
-
0032902502
-
Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect
-
Nishizaki, M. et al. (1999). Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect. Clin Cancer Res 5(5): 1015-1023.
-
(1999)
Clin Cancer Res
, vol.5
, Issue.5
, pp. 1015-1023
-
-
Nishizaki, M.1
-
155
-
-
54949115518
-
Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors
-
Trimis, G. et al. (2008). Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors. Hum Mol Genet 17(22): 3596-3600.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.22
, pp. 3596-3600
-
-
Trimis, G.1
-
156
-
-
28944432805
-
Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis
-
Hill, R. et al. (2005). Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. Cell 123(6): 1001-1011.
-
(2005)
Cell
, vol.123
, Issue.6
, pp. 1001-1011
-
-
Hill, R.1
-
157
-
-
60149098323
-
Cancer cells suppress p53 in adjacent fibroblasts
-
Bar, J. et al. (2009). Cancer cells suppress p53 in adjacent fibroblasts. Oncogene 28(6): 933-936.
-
(2009)
Oncogene
, vol.28
, Issue.6
, pp. 933-936
-
-
Bar, J.1
-
158
-
-
84875977517
-
Loss of p53 in stromal fibroblasts promotes epithelial cell invasion through redox-mediated ICAM1 signal.
-
Trachootham, D. et al. (2013). Loss of p53 in stromal fibroblasts promotes epithelial cell invasion through redox-mediated ICAM1 signal. Free Radic Biol Med 58: 1-13.
-
(2013)
Free Radic Biol Med
, vol.58
, pp. 1-13
-
-
Trachootham, D.1
-
159
-
-
84871865135
-
p53 is renoprotective after ischemic kidney injury by reducing inflammation
-
Sutton, T. A. et al. (2013). p53 is renoprotective after ischemic kidney injury by reducing inflammation. J Am Soc Nephrol 24(1): 113-124.
-
(2013)
J Am Soc Nephrol
, vol.24
, Issue.1
, pp. 113-124
-
-
Sutton, T.A.1
-
160
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
Krizhanovsky, V. et al. (2008). Senescence of activated stellate cells limits liver fibrosis. Cell 134(4): 657-667.
-
(2008)
Cell
, vol.134
, Issue.4
, pp. 657-667
-
-
Krizhanovsky, V.1
-
161
-
-
84876291823
-
Non-cell-autonomous tumor suppression by p53
-
Lujambio, A. et al. (2013). Non-cell-autonomous tumor suppression by p53. Cell 153(2): 449-460.
-
(2013)
Cell
, vol.153
, Issue.2
, pp. 449-460
-
-
Lujambio, A.1
-
162
-
-
0037162491
-
Regional analysis of p53 mutations in rheumatoid arthritis synovium.
-
Yamanishi, Y. et al (2002). Regional analysis of p53 mutations in rheumatoid arthritis synovium. Proc Natl Acad Sci U S A 99(15): 10025-10030.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.15
, pp. 10025-10030
-
-
Yamanishi, Y.1
|