Epstein-Barr Virus Nuclear Antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 1, 2014, Pages 421-426

  Jiang, Sizun ^a,b,c   Willox, Bradford ^a,b   Zhou, Hufeng ^a,b   Holthaus, Amy M ^a,b   Wang, Anqi ^d   Shi, Tommy T ^a,b   Maruo, Seiji ^e   Kharchenko, Peter V ^c,f   Johannsen, Eric C ^d   Kieff, Elliott ^a,b   Zhao, Bo ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Harvard Medical School Center for Biomedical Informatics   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e HOKKAIDO UNIVERSITY   (Japan)

^f BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

EBV; Lymphoma; Resting B lymphocyte; Tumor suppressor

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA; EPSTEIN BARR VIRUS ANTIGEN; EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 3C; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; PROTEIN P14; PROTEIN P16; STAT1 PROTEIN; STAT5 PROTEIN; TRANSCRIPTION FACTOR SIN3A; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HETEROCHROMATIN; HISTONE MODIFICATION; HUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; WESTERN BLOTTING;

EBV; LYMPHOMA; RESTING B LYMPHOCYTE; TUMOR SUPPRESSOR;

AMINO ACID MOTIFS; ANTIGENS, VIRAL; B-LYMPHOCYTES; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BINDING SITES; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HERPESVIRUS 4, HUMAN; HISTONES; HUMANS; INTERFERON REGULATORY FACTORS; LYMPHOMA; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 84891940137     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321704111     Document Type: Article

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