메뉴 건너뛰기




Volumn 25, Issue 1, 2015, Pages 28-33

Combination of Radiotherapy and Immune Checkpoint Inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IPILIMUMAB; PEPTIDE VACCINE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TUMOR VACCINE;

EID: 84919475564     PISSN: 10534296     EISSN: 15329461     Source Type: Journal    
DOI: 10.1016/j.semradonc.2014.07.004     Document Type: Review
Times cited : (119)

References (76)
  • 1
    • 84880145306 scopus 로고    scopus 로고
    • Database of T cell-defined human tumor antigens: The 2013 update
    • Vigneron, Stroobant V., Van den Eynde B.J., et al. Database of T cell-defined human tumor antigens: The 2013 update. Cancer Immun 2013, 13:15.
    • (2013) Cancer Immun , vol.13 , pp. 15
    • Vigneron1    Stroobant, V.2    Van den Eynde, B.J.3
  • 2
    • 78650574270 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines: are we there yet?
    • Klebanoff C.A., Acquavella N., Yu Z., et al. Therapeutic cancer vaccines: are we there yet?. Immunol Rev 2011, 239:27-44.
    • (2011) Immunol Rev , vol.239 , pp. 27-44
    • Klebanoff, C.A.1    Acquavella, N.2    Yu, Z.3
  • 3
    • 84894107349 scopus 로고    scopus 로고
    • New insights into cancer immunoediting and its three component phases-elimination, equilibrium and escape
    • Mittal D., Gubin M.M., Schreiber R.D., et al. New insights into cancer immunoediting and its three component phases-elimination, equilibrium and escape. Curr Opin Immunol 2014, 27C:16-25.
    • (2014) Curr Opin Immunol , vol.27 C , pp. 16-25
    • Mittal, D.1    Gubin, M.M.2    Schreiber, R.D.3
  • 4
    • 84862776855 scopus 로고    scopus 로고
    • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
    • Matsushita H., Vesely M.D., Koboldt D.C., et al. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature 2012, 482:400-404.
    • (2012) Nature , vol.482 , pp. 400-404
    • Matsushita, H.1    Vesely, M.D.2    Koboldt, D.C.3
  • 5
    • 84857725402 scopus 로고    scopus 로고
    • Exploiting the mutanome for tumor vaccination
    • Castle J.C., Kreiter S., Diekmann J., et al. Exploiting the mutanome for tumor vaccination. Cancer Res 2012, 72:1081-1091.
    • (2012) Cancer Res , vol.72 , pp. 1081-1091
    • Castle, J.C.1    Kreiter, S.2    Diekmann, J.3
  • 6
    • 38849151665 scopus 로고    scopus 로고
    • Epitope landscape in breast and colorectal cancer
    • Segal N.H., Parsons D.W., Peggs K.S., et al. Epitope landscape in breast and colorectal cancer. Cancer Res 2008, 68:889-892.
    • (2008) Cancer Res , vol.68 , pp. 889-892
    • Segal, N.H.1    Parsons, D.W.2    Peggs, K.S.3
  • 7
    • 19944365184 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases
    • Buckowitz A., Knaebel H.P., Benner A., et al. Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases. Br J Cancer 2005, 92:1746-1753.
    • (2005) Br J Cancer , vol.92 , pp. 1746-1753
    • Buckowitz, A.1    Knaebel, H.P.2    Benner, A.3
  • 9
    • 84886698315 scopus 로고    scopus 로고
    • Innate and adaptive immune cells in the tumor microenvironment
    • Gajewski T.F., Schreiber H., Fu Y.X. Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol 2013, 14:1014-1022.
    • (2013) Nat Immunol , vol.14 , pp. 1014-1022
    • Gajewski, T.F.1    Schreiber, H.2    Fu, Y.X.3
  • 10
    • 84862769116 scopus 로고    scopus 로고
    • An immune-active tumor microenvironment favors clinical response to ipilimumab
    • Ji R.-R., Chasalow S.D., Wang L., et al. An immune-active tumor microenvironment favors clinical response to ipilimumab. Cancer Immunol Immunother 2012, 61:1019-1031.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 1019-1031
    • Ji, R.-R.1    Chasalow, S.D.2    Wang, L.3
  • 11
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi F.S., O'Day S.J., McDermott D.F., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010, 363:711-723.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 12
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian S.L., Hodi F.S., Brahmer J.R., et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012, 366:2443-2454.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 13
    • 84879777241 scopus 로고    scopus 로고
    • Nivolumab plus Ipilimumab in Advanced Melanoma
    • Wolchok J.D., Kluger H., Callahan M.K., et al. Nivolumab plus Ipilimumab in Advanced Melanoma. N Engl J Med 2013, 369:122-133.
    • (2013) N Engl J Med , vol.369 , pp. 122-133
    • Wolchok, J.D.1    Kluger, H.2    Callahan, M.K.3
  • 14
    • 84859414476 scopus 로고    scopus 로고
    • The antitumor immunity of ipilimumab: (T-cell) memories to last a lifetime?
    • Postow M.A., Callahan M.K., Wolchok J.D. The antitumor immunity of ipilimumab: (T-cell) memories to last a lifetime?. Clin Cancer Res 2012, 18:1821-1823.
    • (2012) Clin Cancer Res , vol.18 , pp. 1821-1823
    • Postow, M.A.1    Callahan, M.K.2    Wolchok, J.D.3
  • 15
    • 77954641944 scopus 로고    scopus 로고
    • Radiation-induced cell death mechanisms
    • Eriksson D., Stigbrand T. Radiation-induced cell death mechanisms. Tumour Biol 2010, 31:363-372.
    • (2010) Tumour Biol , vol.31 , pp. 363-372
    • Eriksson, D.1    Stigbrand, T.2
  • 16
    • 84874418442 scopus 로고    scopus 로고
    • The convergence of radiation and immunogenic cell death signaling pathways
    • Golden E.B., Pellicciotta I., Demaria S., et al. The convergence of radiation and immunogenic cell death signaling pathways. Front Oncol 2012, 2:88.
    • (2012) Front Oncol , vol.2 , pp. 88
    • Golden, E.B.1    Pellicciotta, I.2    Demaria, S.3
  • 17
    • 84902517894 scopus 로고    scopus 로고
    • Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death
    • Golden E.B., Francis D., Pellicciotta I., et al. Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death. OncoImmunology 2014, 3:e28518.
    • (2014) OncoImmunology , vol.3 , pp. e28518
    • Golden, E.B.1    Francis, D.2    Pellicciotta, I.3
  • 18
    • 37349051718 scopus 로고    scopus 로고
    • Molecular characteristics of immunogenic cancer cell death
    • Tesniere A., Panaretakis T., Kepp O., et al. Molecular characteristics of immunogenic cancer cell death. Cell Death Differ 2008, 15:3-12.
    • (2008) Cell Death Differ , vol.15 , pp. 3-12
    • Tesniere, A.1    Panaretakis, T.2    Kepp, O.3
  • 19
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli F., Apetoh L., Tesniere A., et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009, 15:1170-1178.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3
  • 20
    • 79953295544 scopus 로고    scopus 로고
    • The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity
    • Burnette B.C., Liang H., Lee Y., et al. The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Res 2011, 71:2488-2496.
    • (2011) Cancer Res , vol.71 , pp. 2488-2496
    • Burnette, B.C.1    Liang, H.2    Lee, Y.3
  • 21
    • 36849031260 scopus 로고    scopus 로고
    • Sensors of ionizing radiation effects on the immunological microenvironment of cancer
    • Demaria S., Formenti S.C. Sensors of ionizing radiation effects on the immunological microenvironment of cancer. Int J Radiat Biol 2007, 83:819-825.
    • (2007) Int J Radiat Biol , vol.83 , pp. 819-825
    • Demaria, S.1    Formenti, S.C.2
  • 22
    • 51549088023 scopus 로고    scopus 로고
    • Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells
    • Matsumura S., Wang B., Kawashima N., et al. Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. J Immunol 2008, 181:3099-3107.
    • (2008) J Immunol , vol.181 , pp. 3099-3107
    • Matsumura, S.1    Wang, B.2    Kawashima, N.3
  • 23
    • 45449090985 scopus 로고    scopus 로고
    • Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity
    • Lugade A.A., Sorensen E.W., Gerber S.A., et al. Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity. J Immunol 2008, 180:3132-3139.
    • (2008) J Immunol , vol.180 , pp. 3132-3139
    • Lugade, A.A.1    Sorensen, E.W.2    Gerber, S.A.3
  • 24
    • 20444406500 scopus 로고    scopus 로고
    • Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
    • Lugade A.A., Moran J.P., Gerber S.A., et al. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J Immunol 2005, 174:7516-7523.
    • (2005) J Immunol , vol.174 , pp. 7516-7523
    • Lugade, A.A.1    Moran, J.P.2    Gerber, S.A.3
  • 25
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
    • Reits E.A., Hodge J.W., Herberts C.A., et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med 2006, 203:1259-1271.
    • (2006) J Exp Med , vol.203 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3
  • 26
    • 0037942745 scopus 로고    scopus 로고
    • Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy
    • Chakraborty M., Abrams S.I., Camphausen K., et al. Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. J Immunol 2003, 170:6338-6347.
    • (2003) J Immunol , vol.170 , pp. 6338-6347
    • Chakraborty, M.1    Abrams, S.I.2    Camphausen, K.3
  • 27
    • 84867182261 scopus 로고    scopus 로고
    • Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves anti-tumor effects
    • Ruocco M.G., Pilones K.A., Kawashima N., et al. Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves anti-tumor effects. J Clin Invest 2012, 122:3718-3730.
    • (2012) J Clin Invest , vol.122 , pp. 3718-3730
    • Ruocco, M.G.1    Pilones, K.A.2    Kawashima, N.3
  • 28
    • 84878252530 scopus 로고    scopus 로고
    • In the field: Exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer
    • Kwilas A.R., Donahue R.N., Bernstein M.B., et al. In the field: Exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer. Front Oncol 2012, 2:104.
    • (2012) Front Oncol , vol.2 , pp. 104
    • Kwilas, A.R.1    Donahue, R.N.2    Bernstein, M.B.3
  • 29
    • 20944441967 scopus 로고    scopus 로고
    • Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer
    • Gulley J.L., Arlen P.M., Bastian N., et al. Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin Cancer Res 2005, 11:3353-3362.
    • (2005) Clin Cancer Res , vol.11 , pp. 3353-3362
    • Gulley, J.L.1    Arlen, P.M.2    Bastian, N.3
  • 30
    • 67649359533 scopus 로고    scopus 로고
    • Systemic effects of local radiotherapy
    • Formenti S.C., Demaria S. Systemic effects of local radiotherapy. Lancet Oncol 2009, 10:718-726.
    • (2009) Lancet Oncol , vol.10 , pp. 718-726
    • Formenti, S.C.1    Demaria, S.2
  • 31
    • 70149113060 scopus 로고    scopus 로고
    • + T cells: Changing strategies for cancer treatment
    • + T cells: Changing strategies for cancer treatment. Blood 2009, 114:589-595.
    • (2009) Blood , vol.114 , pp. 589-595
    • Lee, Y.1    Auh, S.L.2    Wang, Y.3
  • 32
    • 84857815877 scopus 로고    scopus 로고
    • Immunologic correlates of the abscopal effect in a patient with melanoma
    • Postow M.A., Callahan M.K., Barker C.A., et al. Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med 2012, 366:925-931.
    • (2012) N Engl J Med , vol.366 , pp. 925-931
    • Postow, M.A.1    Callahan, M.K.2    Barker, C.A.3
  • 33
    • 84872202826 scopus 로고    scopus 로고
    • The abscopal effect associated with a systemic anti-melanoma immune response
    • Stamell E.F., Wolchok J.D., Gnjatic S., et al. The abscopal effect associated with a systemic anti-melanoma immune response. Int J Radiat Oncol Biol Phys 2013, 85:293-295.
    • (2013) Int J Radiat Oncol Biol Phys , vol.85 , pp. 293-295
    • Stamell, E.F.1    Wolchok, J.D.2    Gnjatic, S.3
  • 34
    • 84871694504 scopus 로고    scopus 로고
    • A systemic complete response of metastatic melanoma to local radiation and immunotherapy
    • Hiniker S.M., Chen D.S., Reddy S., et al. A systemic complete response of metastatic melanoma to local radiation and immunotherapy. Transl Oncol 2012, 5:404-407.
    • (2012) Transl Oncol , vol.5 , pp. 404-407
    • Hiniker, S.M.1    Chen, D.S.2    Reddy, S.3
  • 35
    • 12244252335 scopus 로고    scopus 로고
    • Immune-mediated inhibition of metastases following treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer
    • Demaria S., Kawashima N., Yang A.M., et al. Immune-mediated inhibition of metastases following treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer. Clin Cancer Res 2005, 11:728-734.
    • (2005) Clin Cancer Res , vol.11 , pp. 728-734
    • Demaria, S.1    Kawashima, N.2    Yang, A.M.3
  • 36
    • 69949085196 scopus 로고    scopus 로고
    • Fractionated but not single dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody
    • Dewan M.Z., Galloway A.E., Kawashima N., et al. Fractionated but not single dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. Clin Cancer Res 2009, 15:5379-5388.
    • (2009) Clin Cancer Res , vol.15 , pp. 5379-5388
    • Dewan, M.Z.1    Galloway, A.E.2    Kawashima, N.3
  • 37
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol E.A., Borriello F., Schweitzer A.N., et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995, 3:541-547.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3
  • 38
    • 0028791059 scopus 로고
    • Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
    • Waterhouse P., Penninger J.M., Timms E., et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995, 270:985-988.
    • (1995) Science , vol.270 , pp. 985-988
    • Waterhouse, P.1    Penninger, J.M.2    Timms, E.3
  • 39
    • 0347505003 scopus 로고    scopus 로고
    • CD28-mediated co-stimulation: a quantitative support for TCR signalling
    • Acuto O., Michel F. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat Rev Immunol 2003, 3:939-951.
    • (2003) Nat Rev Immunol , vol.3 , pp. 939-951
    • Acuto, O.1    Michel, F.2
  • 40
    • 0031054242 scopus 로고    scopus 로고
    • CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
    • van der Merwe P.A., Bodian D.L., Daenke S., et al. CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J Exp Med 1997, 185:393-403.
    • (1997) J Exp Med , vol.185 , pp. 393-403
    • van der Merwe, P.A.1    Bodian, D.L.2    Daenke, S.3
  • 41
    • 0036669785 scopus 로고    scopus 로고
    • The interaction properties of costimulatory molecules revisited
    • Collins A.V., Brodie D.W., Gilbert R.J., et al. The interaction properties of costimulatory molecules revisited. Immunity 2002, 17:201-210.
    • (2002) Immunity , vol.17 , pp. 201-210
    • Collins, A.V.1    Brodie, D.W.2    Gilbert, R.J.3
  • 42
    • 0032545452 scopus 로고    scopus 로고
    • Molecular basis of T cell inactivation by CTLA-4
    • Lee K.M., Chuang E., Griffin M., et al. Molecular basis of T cell inactivation by CTLA-4. Science 1998, 282:2263-2266.
    • (1998) Science , vol.282 , pp. 2263-2266
    • Lee, K.M.1    Chuang, E.2    Griffin, M.3
  • 43
    • 0030001318 scopus 로고    scopus 로고
    • Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
    • Marengere L.E., Waterhouse P., Duncan G.S., et al. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 1996, 272:1170-1173.
    • (1996) Science , vol.272 , pp. 1170-1173
    • Marengere, L.E.1    Waterhouse, P.2    Duncan, G.S.3
  • 44
    • 33749038866 scopus 로고    scopus 로고
    • Reversal of the TCR stop signal by CTLA-4
    • Schneider H., Downey J., Smith A., et al. Reversal of the TCR stop signal by CTLA-4. Science 2006, 313:1972-1975.
    • (2006) Science , vol.313 , pp. 1972-1975
    • Schneider, H.1    Downey, J.2    Smith, A.3
  • 46
    • 0028484545 scopus 로고
    • Ctla-4 can function as a negative regulator of T-cell activation
    • Walunas T.L., Lenschow D.J., Bakker C.Y., et al. Ctla-4 can function as a negative regulator of T-cell activation. Immunity 1994, 1:405-413.
    • (1994) Immunity , vol.1 , pp. 405-413
    • Walunas, T.L.1    Lenschow, D.J.2    Bakker, C.Y.3
  • 47
    • 0025830902 scopus 로고
    • Ctla-4 is a 2nd receptor for the B-Cell activation antigen-B7
    • Linsley P.S., Brady W., Urnes M., et al. Ctla-4 is a 2nd receptor for the B-Cell activation antigen-B7. J Exp Med 1991, 174:561-569.
    • (1991) J Exp Med , vol.174 , pp. 561-569
    • Linsley, P.S.1    Brady, W.2    Urnes, M.3
  • 48
    • 79955529454 scopus 로고    scopus 로고
    • Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4
    • Qureshi O.S., Zheng Y., Nakamura K., et al. Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4. Science 2011, 332:600-603.
    • (2011) Science , vol.332 , pp. 600-603
    • Qureshi, O.S.1    Zheng, Y.2    Nakamura, K.3
  • 49
    • 23844529169 scopus 로고    scopus 로고
    • Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes
    • Wang J., Yoshida T., Nakaki F., et al. Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. Proc Natl Acad Sci U S A 2005, 102:11823-11828.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11823-11828
    • Wang, J.1    Yoshida, T.2    Nakaki, F.3
  • 50
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • Topalian S.L., Drake C.G., Pardoll D.M. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol 2012, 24:207-212.
    • (2012) Curr Opin Immunol , vol.24 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 51
    • 0042170392 scopus 로고    scopus 로고
    • Differential binding properties of B7-H1 and B7-DC to programmed death-1
    • Youngnak P., Kozono Y., Kozono H., et al. Differential binding properties of B7-H1 and B7-DC to programmed death-1. Biochem Biophys Res Commun 2003, 307:672-677.
    • (2003) Biochem Biophys Res Commun , vol.307 , pp. 672-677
    • Youngnak, P.1    Kozono, Y.2    Kozono, H.3
  • 52
    • 31444451661 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274)
    • Lee S.J., Jang B.C., Lee S.W., et al. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274). FEBS Lett 2006, 580:755-762.
    • (2006) FEBS Lett , vol.580 , pp. 755-762
    • Lee, S.J.1    Jang, B.C.2    Lee, S.W.3
  • 53
    • 56049111621 scopus 로고    scopus 로고
    • Interferon-sensitive response element (ISRE) is mainly responsible for IFN-alpha-induced upregulation of programmed death-1 (PD-1) in macrophages
    • Cho H.Y., Lee S.W., Seo S.K., et al. Interferon-sensitive response element (ISRE) is mainly responsible for IFN-alpha-induced upregulation of programmed death-1 (PD-1) in macrophages. Biochim Biophys Acta 2008, 1779:811-819.
    • (2008) Biochim Biophys Acta , vol.1779 , pp. 811-819
    • Cho, H.Y.1    Lee, S.W.2    Seo, S.K.3
  • 54
    • 58149191881 scopus 로고    scopus 로고
    • The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands
    • Kinter A.L., Godbout E.J., McNally J.P., et al. The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands. J Immunol 2008, 181:6738-6746.
    • (2008) J Immunol , vol.181 , pp. 6738-6746
    • Kinter, A.L.1    Godbout, E.J.2    McNally, J.P.3
  • 55
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • Dong H., Strome S.E., Salomao D.R., et al. Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion. Nat Med 2002, 8:793-800.
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3
  • 56
    • 84898843963 scopus 로고    scopus 로고
    • Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma
    • Zhang Y., Wang L., Li Y., et al. Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma. Onco Targets Ther 2014, 7:567-573.
    • (2014) Onco Targets Ther , vol.7 , pp. 567-573
    • Zhang, Y.1    Wang, L.2    Li, Y.3
  • 57
    • 33645736792 scopus 로고    scopus 로고
    • Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
    • Thompson R.H., Kuntz S.M., Leibovich B.C., et al. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res 2006, 66:3381-3385.
    • (2006) Cancer Res , vol.66 , pp. 3381-3385
    • Thompson, R.H.1    Kuntz, S.M.2    Leibovich, B.C.3
  • 58
    • 84859128199 scopus 로고    scopus 로고
    • Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
    • Taube J.M., Anders R.A., Young G.D., et al. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med 2012, 4:127ra137.
    • (2012) Sci Transl Med , vol.4 , pp. 127ra137
    • Taube, J.M.1    Anders, R.A.2    Young, G.D.3
  • 59
    • 43549115533 scopus 로고    scopus 로고
    • B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells
    • Azuma T1 Y.S., Zhu G., Flies A.S., et al. B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells. Blood 2008, 111:3635-3643.
    • (2008) Blood , vol.111 , pp. 3635-3643
    • Azuma T1, Y.S.1    Zhu, G.2    Flies, A.S.3
  • 60
    • 84875171283 scopus 로고    scopus 로고
    • PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction
    • Abiko K., Mandai M., Hamanishi J., et al. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clin Cancer Res 2013, 19:1363-1374.
    • (2013) Clin Cancer Res , vol.19 , pp. 1363-1374
    • Abiko, K.1    Mandai, M.2    Hamanishi, J.3
  • 61
    • 13444270323 scopus 로고    scopus 로고
    • Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
    • Hirano F., Kaneko K., Tamura H., et al. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res 2005, 65:1089-1096.
    • (2005) Cancer Res , vol.65 , pp. 1089-1096
    • Hirano, F.1    Kaneko, K.2    Tamura, H.3
  • 62
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of anti-tumor immunity by CTLA4-blockade
    • Leach D., Krummel M., Allison J.P. Enhancement of anti-tumor immunity by CTLA4-blockade. Science 1996, 271:1734-1736.
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.1    Krummel, M.2    Allison, J.P.3
  • 63
    • 45149111788 scopus 로고    scopus 로고
    • Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy
    • Peggs K.S., Quezada S.A., Allison J.P. Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy. Immunol Rev 2008, 224:141-165.
    • (2008) Immunol Rev , vol.224 , pp. 141-165
    • Peggs, K.S.1    Quezada, S.A.2    Allison, J.P.3
  • 64
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • van Elsas A., Hurwitz A.A., Allison J.P. Combination immunotherapy of B16 melanoma using anti-cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 1999, 190:355-366.
    • (1999) J Exp Med , vol.190 , pp. 355-366
    • van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 65
    • 84857725402 scopus 로고    scopus 로고
    • Exploiting the mutanome for tumor vaccination
    • Castle J.C., Kreiter S., Diekmann J., et al. Exploiting the mutanome for tumor vaccination. Cancer Res 2012, 72:1081-1091.
    • (2012) Cancer Res , vol.72 , pp. 1081-1091
    • Castle, J.C.1    Kreiter, S.2    Diekmann, J.3
  • 66
    • 85003053854 scopus 로고    scopus 로고
    • An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer
    • Golden E.B., Demaria S., Schiff P.B., et al. An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer. Cancer Immunol Res 2013, 1:365-372.
    • (2013) Cancer Immunol Res , vol.1 , pp. 365-372
    • Golden, E.B.1    Demaria, S.2    Schiff, P.B.3
  • 67
    • 0141953992 scopus 로고    scopus 로고
    • B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
    • Strome S.E., Dong H., Tamura H., et al. B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma. Cancer Res 2003, 63:6501-6505.
    • (2003) Cancer Res , vol.63 , pp. 6501-6505
    • Strome, S.E.1    Dong, H.2    Tamura, H.3
  • 68
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y., Ishida M., Tanaka Y., et al. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A 2002, 99:12293-12297.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3
  • 69
    • 77951637543 scopus 로고    scopus 로고
    • Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma
    • Pilon-Thomas S., Mackay A., Vohra N., et al. Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma. J Immunol 2010, 184:3442-3449.
    • (2010) J Immunol , vol.184 , pp. 3442-3449
    • Pilon-Thomas, S.1    Mackay, A.2    Vohra, N.3
  • 71
    • 70449395259 scopus 로고    scopus 로고
    • Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model
    • Okudaira K., Hokari R., Tsuzuki Y., et al. Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model. Int J Oncol 2009, 35:741-749.
    • (2009) Int J Oncol , vol.35 , pp. 741-749
    • Okudaira, K.1    Hokari, R.2    Tsuzuki, Y.3
  • 72
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer J.R., Tykodi S.S., Chow L.Q., et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012, 366:2455-2465.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 73
    • 84877581852 scopus 로고    scopus 로고
    • Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
    • Zeng J., See A.P., Phallen J., et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys 2013, 86:343-349.
    • (2013) Int J Radiat Oncol Biol Phys , vol.86 , pp. 343-349
    • Zeng, J.1    See, A.P.2    Phallen, J.3
  • 74
    • 84893876109 scopus 로고    scopus 로고
    • Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice
    • Deng L., Liang H., Burnette B., et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest 2014, 124:687-695.
    • (2014) J Clin Invest , vol.124 , pp. 687-695
    • Deng, L.1    Liang, H.2    Burnette, B.3
  • 75
    • 79960918412 scopus 로고    scopus 로고
    • Emerging Tim-3 functions in antimicrobial and tumor immunity
    • Sakuishi K., Jayaraman P., Behar S.M., et al. Emerging Tim-3 functions in antimicrobial and tumor immunity. Trends Immunol 2011, 32:345-349.
    • (2011) Trends Immunol , vol.32 , pp. 345-349
    • Sakuishi, K.1    Jayaraman, P.2    Behar, S.M.3
  • 76
    • 78650208859 scopus 로고    scopus 로고
    • The CD4-like molecule LAG-3, biology and therapeutic applications
    • Sierro S., Romero P., Speiser D.E. The CD4-like molecule LAG-3, biology and therapeutic applications. Expert Opin Ther Targets 2011, 15:91-101.
    • (2011) Expert Opin Ther Targets , vol.15 , pp. 91-101
    • Sierro, S.1    Romero, P.2    Speiser, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.