Intracellular retention of the NKG2D ligand MHC class i chain-related gene a in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity

Journal of Immunology

Volumn 180, Issue 7, 2008, Pages 4606-4614

  Fuertes, Mercedes B ^a,d   Girart, María V ^a,d   Molinero, Luciana L ^a,e   Domaica, Carolina I ^a,d   Rossi, Lucas E ^a,d   Barrio, María M ^b   Mordoh, José ^b,c   Rabinovich, Gabriel A ^a,d   Zwirner, Norberto W ^a,d  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Centro de Investigaciones Oncológicas   (Argentina)

^c FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^d INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEASOME; MHC CLASS I RELATED CHAIN A; MHC CLASS I-RELATED CHAIN A; SIGNAL PEPTIDE; ULBP2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL COMPARTMENTALIZATION; CELL SURFACE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; ENDOPLASMIC RETICULUM; FEMALE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; IN VITRO STUDY; ISOLATION PROCEDURE; MELANOMA; MHC CLASS 1 CHAIN RELATED GENE A; MHC CLASS 1 CHAIN RELATED GENE B; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; CELL PROLIFERATION; IMMUNOELECTRON MICROSCOPY; IMMUNOLOGY; PATHOLOGY; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE; ULTRASTRUCTURE;

CELL LINE, TUMOR; CELL PROLIFERATION; CYTOTOXICITY, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; MELANOMA; MICROSCOPY, IMMUNOELECTRON; SENSITIVITY AND SPECIFICITY;

EID: 44449119045     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.7.4606     Document Type: Article

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