메뉴 건너뛰기




Volumn 95, Issue PART 5, 2014, Pages 991-1004

'Liver let die': Oxidative DNA damage and hepatotropic viruses

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

EID: 84899689822     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.059485-0     Document Type: Review
Times cited : (77)

References (104)
  • 2
    • 52649086846 scopus 로고    scopus 로고
    • The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication
    • Ariumi, Y., Kuroki, M., Dansako, H., Abe, K., Ikeda, M., Wakita, T. & Kato, N. (2008). The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication. J Virol 82, 9639-9646.
    • (2008) J Virol , vol.82 , pp. 9639-9646
    • Ariumi, Y.1    Kuroki, M.2    Dansako, H.3    Abe, K.4    Ikeda, M.5    Wakita, T.6    Kato, N.7
  • 5
    • 27844562708 scopus 로고    scopus 로고
    • Increased oxidative stress associated with the severity of the liver disease in various forms of hepatitis B virus infection
    • Bolukbas, C., Bolukbas, F. F., Horoz, M., Aslan, M., Celik, H. & Erel, O. (2005). Increased oxidative stress associated with the severity of the liver disease in various forms of hepatitis B virus infection. BMC Infect Dis 5, 95.
    • (2005) BMC Infect Dis , vol.5 , pp. 95
    • Bolukbas, C.1    Bolukbas, F.F.2    Horoz, M.3    Aslan, M.4    Celik, H.5    Erel, O.6
  • 6
    • 72849147487 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor betadependent manner: A new contributor to HCV-induced oxidative stress
    • Boudreau, H. E., Emerson, S. U., Korzeniowska, A., Jendrysik, M. A. & Leto, T. L. (2009). Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor betadependent manner: a new contributor to HCV-induced oxidative stress. J Virol 83, 12934-12946.
    • (2009) J Virol , vol.83 , pp. 12934-12946
    • Boudreau, H.E.1    Emerson, S.U.2    Korzeniowska, A.3    Jendrysik, M.A.4    Leto, T.L.5
  • 7
    • 7044260782 scopus 로고    scopus 로고
    • Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: Old and new paradigms
    • Bréchot, C. (2004). Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms. Gastroenterology 127 (Suppl 1), S56-S61.
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL. 1
    • Bréchot, C.1
  • 8
    • 76849085285 scopus 로고    scopus 로고
    • Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway
    • Burdette, D., Olivarez, M. & Waris, G. (2010). Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway. J Gen Virol 91, 681-690.
    • (2010) J Gen Virol , vol.91 , pp. 681-690
    • Burdette, D.1    Olivarez, M.2    Waris, G.3
  • 10
    • 84873022472 scopus 로고    scopus 로고
    • Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein
    • Chan, C., Wang, Y., Chow, P. K., Chung, A. Y., Ooi, L. L. & Lee, C. G. (2013). Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein. Mol Cell Biol 33, 485-497.
    • (2013) Mol Cell Biol , vol.33 , pp. 485-497
    • Chan, C.1    Wang, Y.2    Chow, P.K.3    Chung, A.Y.4    Ooi, L.L.5    Lee, C.G.6
  • 11
    • 84865364870 scopus 로고    scopus 로고
    • Playing the end game: DNA double-strand break repair pathway choice
    • Chapman, J. R., Taylor, M. R. & Boulton, S. J. (2012). Playing the end game: DNA double-strand break repair pathway choice. Mol Cell 47, 497-510.
    • (2012) Mol Cell , vol.47 , pp. 497-510
    • Chapman, J.R.1    Taylor, M.R.2    Boulton, S.J.3
  • 12
    • 84867478618 scopus 로고    scopus 로고
    • New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress
    • Chen, B. P., Li, M. & Asaithamby, A. (2012). New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress. Cancer Lett 327, 103-110.
    • (2012) Cancer Lett , vol.327 , pp. 103-110
    • Chen, B.P.1    Li, M.2    Asaithamby, A.3
  • 13
    • 0038418494 scopus 로고    scopus 로고
    • Hepatitis B virus X protein modulates the expression of PTEN by inhibiting the function of p53, a transcriptional activator in liver cells
    • Chung, T. W., Lee, Y. C., Ko, J. H. & Kim, C. H. (2003). Hepatitis B virus X protein modulates the expression of PTEN by inhibiting the function of p53, a transcriptional activator in liver cells. Cancer Res 63, 3453-3458.
    • (2003) Cancer Res , vol.63 , pp. 3453-3458
    • Chung, T.W.1    Lee, Y.C.2    Ko, J.H.3    Kim, C.H.4
  • 14
    • 0036140134 scopus 로고    scopus 로고
    • Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation
    • Dandri, M., Burda, M. R., Bürkle, A., Zuckerman, D. M., Will, H., Rogler, C. E., Greten, H. & Petersen, J. (2002). Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation. Hepatology 35, 217-223.
    • (2002) Hepatology , vol.35 , pp. 217-223
    • Dandri, M.1    Burda, M.R.2    Bürkle, A.3    Zuckerman, D.M.4    Will, H.5    Rogler, C.E.6    Greten, H.7    Petersen, J.8
  • 15
    • 39049194778 scopus 로고    scopus 로고
    • Could MYC induction of mitochondrial biogenesis be linked to ROS production and genomic instability?
    • Dang, C. V., Li, F. & Lee, L. A. (2005). Could MYC induction of mitochondrial biogenesis be linked to ROS production and genomic instability? Cell Cycle 4, 1465-1466.
    • (2005) Cell Cycle , vol.4 , pp. 1465-1466
    • Dang, C.V.1    Li, F.2    Lee, L.A.3
  • 16
    • 0037563386 scopus 로고    scopus 로고
    • Levels of plasma malondialdehyde and erythrocyte antioxidant enzyme activities in patients with chronic hepatitis B
    • Demirdag, K., Yilmaz, S., Ozdarendeli, A., Ozden, M., Kalkan, A. & Kilic, S. S. (2003). Levels of plasma malondialdehyde and erythrocyte antioxidant enzyme activities in patients with chronic hepatitis B. Hepatogastroenterology 50, 766-770.
    • (2003) Hepatogastroenterology , vol.50 , pp. 766-770
    • Demirdag, K.1    Yilmaz, S.2    Ozdarendeli, A.3    Ozden, M.4    Kalkan, A.5    Kilic, S.S.6
  • 17
    • 33744791738 scopus 로고    scopus 로고
    • NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner
    • Deng, L., Nagano-Fujii, M., Tanaka, M., Nomura-Takigawa, Y., Ikeda, M., Kato, N., Sada, K. & Hotta, H. (2006). NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner. J Gen Virol 87, 1703-1713.
    • (2006) J Gen Virol , vol.87 , pp. 1703-1713
    • Deng, L.1    Nagano-Fujii, M.2    Tanaka, M.3    Nomura-Takigawa, Y.4    Ikeda, M.5    Kato, N.6    Sada, K.7    Hotta, H.8
  • 18
    • 80052290588 scopus 로고    scopus 로고
    • Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway
    • Deng, L., Shoji, I., Ogawa, W., Kaneda, S., Soga, T., Jiang, D. P., Ide, Y. H. & Hotta, H. (2011). Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway. J Virol 85, 8556-8568.
    • (2011) J Virol , vol.85 , pp. 8556-8568
    • Deng, L.1    Shoji, I.2    Ogawa, W.3    Kaneda, S.4    Soga, T.5    Jiang, D.P.6    Ide, Y.H.7    Hotta, H.8
  • 19
    • 84872038565 scopus 로고    scopus 로고
    • Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach
    • Ding, D., Lou, X., Hua, D., Yu, W., Li, L., Wang, J., Gao, F., Zhao, N., Ren, G. & other authors (2012). Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet 8, e1003065.
    • (2012) PLoS Genet , vol.8
    • Ding, D.1    Lou, X.2    Hua, D.3    Yu, W.4    Li, L.5    Wang, J.6    Gao, F.7    Zhao, N.8    Ren, G.9
  • 20
    • 0036829856 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and hepatitis C in the United States
    • El-Serag, H. B. (2002). Hepatocellular carcinoma and hepatitis C in the United States. Hepatology 36 (Suppl 1), S74-S83.
    • (2002) Hepatology , vol.36 , Issue.SUPPL. 1
    • El-Serag, H.B.1
  • 23
    • 65349100528 scopus 로고    scopus 로고
    • Redox signaling across cell membranes
    • Fisher, A. B. (2009). Redox signaling across cell membranes. Antioxid Redox Signal 11, 1349-1356.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1349-1356
    • Fisher, A.B.1
  • 25
    • 0035859871 scopus 로고    scopus 로고
    • Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B
    • Gong, G., Waris, G., Tanveer, R. & Siddiqui, A. (2001). Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc Natl Acad Sci U S A 98, 9599-9604.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9599-9604
    • Gong, G.1    Waris, G.2    Tanveer, R.3    Siddiqui, A.4
  • 26
    • 65249185741 scopus 로고    scopus 로고
    • Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc
    • Graves, J. A., Metukuri, M., Scott, D., Rothermund, K. & Prochownik, E. V. (2009). Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc. J Biol Chem 284, 6520-6529.
    • (2009) J Biol Chem , vol.284 , pp. 6520-6529
    • Graves, J.A.1    Metukuri, M.2    Scott, D.3    Rothermund, K.4    Prochownik, E.V.5
  • 27
    • 34547812145 scopus 로고    scopus 로고
    • Activated neutrophils inhibit nucleotide excision repair in human pulmonary epithelial cells: Role of myeloperoxidase
    • Güngör, N., Godschalk, R. W., Pachen, D. M., Van Schooten, F. J. & Knaapen, A. M. (2007). Activated neutrophils inhibit nucleotide excision repair in human pulmonary epithelial cells: role of myeloperoxidase. FASEB J 21, 2359-2367.
    • (2007) FASEB J , vol.21 , pp. 2359-2367
    • Güngör, N.1    Godschalk, R.W.2    Pachen, D.M.3    Van Schooten, F.J.4    Knaapen, A.M.5
  • 28
    • 78650378982 scopus 로고    scopus 로고
    • ATM activation in the presence of oxidative stress
    • Guo, Z., Deshpande, R. & Paull, T. T. (2010). ATM activation in the presence of oxidative stress. Cell Cycle 9, 4805-4811.
    • (2010) Cell Cycle , vol.9 , pp. 4805-4811
    • Guo, Z.1    Deshpande, R.2    Paull, T.T.3
  • 30
    • 0028567172 scopus 로고
    • Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma
    • Hagen, T. M., Huang, S., Curnutte, J., Fowler, P., Martinez, V., Wehr, C. M., Ames, B. N. & Chisari, F. V. (1994). Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Proc Natl Acad Sci U S A 91, 12808-12812.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12808-12812
    • Hagen, T.M.1    Huang, S.2    Curnutte, J.3    Fowler, P.4    Martinez, V.5    Wehr, C.M.6    Ames, B.N.7    Chisari, F.V.8
  • 31
    • 77953790550 scopus 로고    scopus 로고
    • Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest
    • Higgs, M. R., Lerat, H. & Pawlotsky, J. M. (2010). Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest. Cancer Res 70, 4901-4911.
    • (2010) Cancer Res , vol.70 , pp. 4901-4911
    • Higgs, M.R.1    Lerat, H.2    Pawlotsky, J.M.3
  • 32
    • 84884907504 scopus 로고    scopus 로고
    • Hepatitis C virusinduced activation of beta-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events
    • Higgs, M. R., Lerat, H. & Pawlotsky, J. M. (2012). Hepatitis C virusinduced activation of beta-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events. Oncogene 32, 4683-4693.
    • (2012) Oncogene , vol.32 , pp. 4683-4693
    • Higgs, M.R.1    Lerat, H.2    Pawlotsky, J.M.3
  • 34
    • 6444242588 scopus 로고    scopus 로고
    • Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage
    • Hsieh, Y. H., Su, I. J., Wang, H. C., Chang, W. W., Lei, H. Y., Lai, M. D., Chang, W. T. & Huang, W. (2004). Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage. Carcinogenesis 25, 2023-2032.
    • (2004) Carcinogenesis , vol.25 , pp. 2023-2032
    • Hsieh, Y.H.1    Su, I.J.2    Wang, H.C.3    Chang, W.W.4    Lei, H.Y.5    Lai, M.D.6    Chang, W.T.7    Huang, W.8
  • 35
    • 79954600763 scopus 로고    scopus 로고
    • HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade
    • Hu, L., Chen, L., Yang, G., Li, L., Sun, H., Chang, Y., Tu, Q., Wu, M. & Wang, H. (2011). HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade. Mol Cancer 10, 43.
    • (2011) Mol Cancer , vol.10 , pp. 43
    • Hu, L.1    Chen, L.2    Yang, G.3    Li, L.4    Sun, H.5    Chang, Y.6    Tu, Q.7    Wu, M.8    Wang, H.9
  • 37
    • 18044386970 scopus 로고    scopus 로고
    • Redox regulation of the transcriptional repressor Bach1
    • Ishikawa, M., Numazawa, S. & Yoshida, T. (2005). Redox regulation of the transcriptional repressor Bach1. Free Radic Biol Med 38, 1344-1352.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1344-1352
    • Ishikawa, M.1    Numazawa, S.2    Yoshida, T.3
  • 39
    • 80052750522 scopus 로고    scopus 로고
    • Hepatitis C virus proteins activate NRF2/ARE pathway by distinct ROS-dependent and independent mechanisms in HUH7 cells
    • Ivanov, A. V., Smirnova, O. A., Ivanova, O. N., Masalova, O. V., Kochetkov, S. N. & Isaguliants, M. G. (2011). Hepatitis C virus proteins activate NRF2/ARE pathway by distinct ROS-dependent and independent mechanisms in HUH7 cells. PloS One 6, e24957.
    • (2011) PloS One , vol.6
    • Ivanov, A.V.1    Smirnova, O.A.2    Ivanova, O.N.3    Masalova, O.V.4    Kochetkov, S.N.5    Isaguliants, M.G.6
  • 41
    • 78650769395 scopus 로고    scopus 로고
    • Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts
    • Jaeschke, H. (2011). Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts. J Gastroenterol Hepatol 26 (Suppl 1), 173-179.
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.SUPPL. 1 , pp. 173-179
    • Jaeschke, H.1
  • 42
    • 0035957917 scopus 로고    scopus 로고
    • Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue
    • Jaitovich-Groisman, I., Benlimame, N., Slagle, B. L., Perez, M. H., Alpert, L., Song, D. J., Fotouhi-Ardakani, N., Galipeau, J. & Alaoui-Jamali, M. A. (2001). Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue. J Biol Chem 276, 14124-14132.
    • (2001) J Biol Chem , vol.276 , pp. 14124-14132
    • Jaitovich-Groisman, I.1    Benlimame, N.2    Slagle, B.L.3    Perez, M.H.4    Alpert, L.5    Song, D.J.6    Fotouhi-Ardakani, N.7    Galipeau, J.8    Alaoui-Jamali, M.A.9
  • 43
    • 0033559939 scopus 로고    scopus 로고
    • Hepatitis B virus X protein inhibits nucleotide excision repair
    • Jia, L., Wang, X. W. & Harris, C. C. (1999). Hepatitis B virus X protein inhibits nucleotide excision repair. Int J Cancer 80, 875-879.
    • (1999) Int J Cancer , vol.80 , pp. 875-879
    • Jia, L.1    Wang, X.W.2    Harris, C.C.3
  • 44
    • 1942436893 scopus 로고    scopus 로고
    • Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein
    • Kao, C.-F., Chen, S.-Y., Chen, J.-Y. & Wu Lee, Y.-H. (2004). Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein. Oncogene 23, 2472-2483.
    • (2004) Oncogene , vol.23 , pp. 2472-2483
    • Kao, C.-F.1    Chen, S.-Y.2    Chen, J.-Y.3    Wu Lee, Y.-H.4
  • 45
    • 0043193855 scopus 로고    scopus 로고
    • Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression
    • Karlsson, A., Deb-Basu, D., Cherry, A., Turner, S., Ford, J. & Felsher, D. W. (2003). Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression. Proc Natl Acad Sci U S A 100, 9974-9979.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9974-9979
    • Karlsson, A.1    Deb-Basu, D.2    Cherry, A.3    Turner, S.4    Ford, J.5    Felsher, D.W.6
  • 46
    • 0035893552 scopus 로고    scopus 로고
    • Normalization of elevated hepatic 8-hydroxy-29-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet
    • Kato, J., Kobune, M., Nakamura, T., Kuroiwa, G., Takada, K., Takimoto, R., Sato, Y., Fujikawa, K., Takahashi, M. & other authors (2001). Normalization of elevated hepatic 8-hydroxy-29-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet. Cancer Res 61, 8697-8702.
    • (2001) Cancer Res , vol.61 , pp. 8697-8702
    • Kato, J.1    Kobune, M.2    Nakamura, T.3    Kuroiwa, G.4    Takada, K.5    Takimoto, R.6    Sato, Y.7    Fujikawa, K.8    Takahashi, M.9
  • 47
    • 48849116019 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces apoptosis by enhancing translocation of Bax to mitochondria
    • Kim, H. J., Kim, S. Y., Kim, J., Lee, H., Choi, M., Kim, J. K. & Ahn, J. K. (2008). Hepatitis B virus X protein induces apoptosis by enhancing translocation of Bax to mitochondria. IUBMB Life 60, 473-480.
    • (2008) IUBMB Life , vol.60 , pp. 473-480
    • Kim, H.J.1    Kim, S.Y.2    Kim, J.3    Lee, H.4    Choi, M.5    Kim, J.K.6    Ahn, J.K.7
  • 48
    • 34249779862 scopus 로고    scopus 로고
    • Hepatitis C virus contributes to hepatocarcinogenesis by modulating metabolic and intracellular signaling pathways
    • Koike, K. (2007). Hepatitis C virus contributes to hepatocarcinogenesis by modulating metabolic and intracellular signaling pathways. J Gastroenterol Hepatol 22 (Suppl 1), S108-S111.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.SUPPL. 1
    • Koike, K.1
  • 49
    • 33750097483 scopus 로고    scopus 로고
    • Increased lipid peroxidation in patients with non-alcoholic fatty liver disease and chronic hepatitis C as measured by the plasma level of 8-isoprostane
    • Konishi, M., Iwasa, M., Araki, J., Kobayashi, Y., Katsuki, A., Sumida, Y., Nakagawa, N., Kojima, Y., Watanabe, S. & other authors (2006). Increased lipid peroxidation in patients with non-alcoholic fatty liver disease and chronic hepatitis C as measured by the plasma level of 8-isoprostane. J Gastroenterol Hepatol 21, 1821-1825.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 1821-1825
    • Konishi, M.1    Iwasa, M.2    Araki, J.3    Kobayashi, Y.4    Katsuki, A.5    Sumida, Y.6    Nakagawa, N.7    Kojima, Y.8    Watanabe, S.9
  • 50
    • 27844604269 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production
    • Korenaga, M., Wang, T., Li, Y., Showalter, L. A., Chan, T., Sun, J. & Weinman, S. A. (2005). Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J Biol Chem 280, 37481-37488.
    • (2005) J Biol Chem , vol.280 , pp. 37481-37488
    • Korenaga, M.1    Wang, T.2    Li, Y.3    Showalter, L.A.4    Chan, T.5    Sun, J.6    Weinman, S.A.7
  • 51
    • 0034636004 scopus 로고    scopus 로고
    • Removal of oxygen free-radical-induced 59, 8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
    • Kuraoka, I., Bender, C., Romieu, A., Cadet, J., Wood, R. D. & Lindahl, T. (2000). Removal of oxygen free-radical-induced 59, 8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells. Proc Natl Acad Sci U S A 97, 3832-3837.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3832-3837
    • Kuraoka, I.1    Bender, C.2    Romieu, A.3    Cadet, J.4    Wood, R.D.5    Lindahl, T.6
  • 52
    • 0037707408 scopus 로고    scopus 로고
    • Dual effects of hepatitis C virus Core protein on the transcription of cyclin-dependent kinase inhibitor p21 gene
    • Kwun, H. J. & Jang, K. L. (2003). Dual effects of hepatitis C virus Core protein on the transcription of cyclin-dependent kinase inhibitor p21 gene. J Viral Hepat 10, 249-255.
    • (2003) J Viral Hepat , vol.10 , pp. 249-255
    • Kwun, H.J.1    Jang, K.L.2
  • 54
    • 0034307185 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells
    • Le Page, F., Randrianarison, V., Marot, D., Cabannes, J., Perricaudet, M., Feunteun, J. & Sarasin, A. (2000). BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells. Cancer Res 60, 5548-5552.
    • (2000) Cancer Res , vol.60 , pp. 5548-5552
    • Le Page, F.1    Randrianarison, V.2    Marot, D.3    Cabannes, J.4    Perricaudet, M.5    Feunteun, J.6    Sarasin, A.7
  • 55
    • 2442452762 scopus 로고    scopus 로고
    • Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells
    • Lee, Y. I., Hwang, J. M., Im, J. H., Lee, Y. I., Kim, N. S., Kim, D. G., Yu, D. Y., Moon, H. B. & Park, S. K. (2004). Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells. J Biol Chem 279, 15460-15471.
    • (2004) J Biol Chem , vol.279 , pp. 15460-15471
    • Lee, Y.I.1    Hwang, J.M.2    Im, J.H.3    Lee, Y.I.4    Kim, N.S.5    Kim, D.G.6    Yu, D.Y.7    Moon, H.B.8    Park, S.K.9
  • 56
    • 25844447771 scopus 로고    scopus 로고
    • The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage
    • Lee, A. T., Ren, J., Wong, E. T., Ban, K. H., Lee, L. A. & Lee, C. G. (2005). The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage. J Biol Chem 280, 33525-33535.
    • (2005) J Biol Chem , vol.280 , pp. 33525-33535
    • Lee, A.T.1    Ren, J.2    Wong, E.T.3    Ban, K.H.4    Lee, L.A.5    Lee, C.G.6
  • 58
    • 79958268921 scopus 로고    scopus 로고
    • Animal models in the study of hepatitis C virus-associated liver pathologies
    • Lerat, H., Higgs, M. & Pawlotsky, J. M. (2011). Animal models in the study of hepatitis C virus-associated liver pathologies. Expert Rev Gastroenterol Hepatol 5, 341-352.
    • (2011) Expert Rev Gastroenterol Hepatol , vol.5 , pp. 341-352
    • Lerat, H.1    Higgs, M.2    Pawlotsky, J.M.3
  • 59
    • 0036236226 scopus 로고    scopus 로고
    • Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells
    • Li, K., Prow, T., Lemon, S. M. & Beard, M. R. (2002). Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells. Hepatology 35, 1237-1246.
    • (2002) Hepatology , vol.35 , pp. 1237-1246
    • Li, K.1    Prow, T.2    Lemon, S.M.3    Beard, M.R.4
  • 60
    • 68549086862 scopus 로고    scopus 로고
    • Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-kappaB activation
    • Li, S., Ye, L., Yu, X., Xu, B., Li, K., Zhu, X., Liu, H., Wu, X. & Kong, L. (2009). Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-kappaB activation. Virology 391, 257-264.
    • (2009) Virology , vol.391 , pp. 257-264
    • Li, S.1    Ye, L.2    Yu, X.3    Xu, B.4    Li, K.5    Zhu, X.6    Liu, H.7    Wu, X.8    Kong, L.9
  • 61
    • 0030724749 scopus 로고    scopus 로고
    • The transactivation and p53-interacting functions of hepatitis B virus X protein are mutually interfering but distinct
    • Lin, Y., Nomura, T., Yamashita, T., Dorjsuren, D., Tang, H. & Murakami, S. (1997). The transactivation and p53-interacting functions of hepatitis B virus X protein are mutually interfering but distinct. Cancer Res 57, 5137-5142.
    • (1997) Cancer Res , vol.57 , pp. 5137-5142
    • Lin, Y.1    Nomura, T.2    Yamashita, T.3    Dorjsuren, D.4    Tang, H.5    Murakami, S.6
  • 62
    • 33745797050 scopus 로고    scopus 로고
    • Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation
    • Machida, K., Cheng, K. T.-H., Lai, C.-K., Jeng, K.-S., Sung, V. M.-H. & Lai, M. M. C. (2006). Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation. J Virol 80, 7199-7207.
    • (2006) J Virol , vol.80 , pp. 7199-7207
    • Machida, K.1    Cheng, K.T.-H.2    Lai, C.-K.3    Jeng, K.-S.4    Sung, V.M.-H.5    Lai, M.M.C.6
  • 63
    • 77955702663 scopus 로고    scopus 로고
    • c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair
    • Machida, K., Tsukamoto, H., Liu, J. C., Han, Y. P., Govindarajan, S., Lai, M. M., Akira, S. & Ou, J. H. (2010a). c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair. Hepatology 52, 480-492.
    • (2010) Hepatology , vol.52 , pp. 480-492
    • Machida, K.1    Tsukamoto, H.2    Liu, J.C.3    Han, Y.P.4    Govindarajan, S.5    Lai, M.M.6    Akira, S.7    Ou, J.H.8
  • 64
    • 78650667610 scopus 로고    scopus 로고
    • Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes
    • Machida, K., McNamara, G., Cheng, K. T., Huang, J., Wang, C. H., Comai, L., Ou, J. H. & Lai, M. M. (2010b). Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes. J Immunol 185, 6985-6998.
    • (2010) J Immunol , vol.185 , pp. 6985-6998
    • Machida, K.1    McNamara, G.2    Cheng, K.T.3    Huang, J.4    Wang, C.H.5    Comai, L.6    Ou, J.H.7    Lai, M.M.8
  • 66
    • 4344634335 scopus 로고    scopus 로고
    • Expression of hepatitis B virus X oncoprotein inhibits transcription-coupled nucleotide excision repair in human cells
    • Mathonnet, G., Lachance, S., Alaoui-Jamali, M. & Drobetsky, E. A. (2004). Expression of hepatitis B virus X oncoprotein inhibits transcription-coupled nucleotide excision repair in human cells. Mutat Res 554, 305-318.
    • (2004) Mutat Res , vol.554 , pp. 305-318
    • Mathonnet, G.1    Lachance, S.2    Alaoui-Jamali, M.3    Drobetsky, E.A.4
  • 67
    • 84871959255 scopus 로고    scopus 로고
    • Nucleotide excision repair-initiating proteins bind to oxidative DNA lesions in vivo
    • Menoni, H., Hoeijmakers, J. H. & Vermeulen, W. (2012). Nucleotide excision repair-initiating proteins bind to oxidative DNA lesions in vivo. J Cell Biol 199, 1037-1046.
    • (2012) J Cell Biol , vol.199 , pp. 1037-1046
    • Menoni, H.1    Hoeijmakers, J.H.2    Vermeulen, W.3
  • 68
    • 33646114053 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting BclxL expression
    • Miao, J., Chen, G. G., Chun, S. Y. & Lai, P. P. (2006). Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting BclxL expression. Cancer Lett 236, 115-124.
    • (2006) Cancer Lett , vol.236 , pp. 115-124
    • Miao, J.1    Chen, G.G.2    Chun, S.Y.3    Lai, P.P.4
  • 69
    • 56149115918 scopus 로고    scopus 로고
    • Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity
    • Miura, K., Taura, K., Kodama, Y., Schnabl, B. & Brenner, D. A. (2008). Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. Hepatology 48, 1420-1429.
    • (2008) Hepatology , vol.48 , pp. 1420-1429
    • Miura, K.1    Taura, K.2    Kodama, Y.3    Schnabl, B.4    Brenner, D.A.5
  • 70
    • 0035360859 scopus 로고    scopus 로고
    • Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis
    • Moriya, K., Nakagawa, K., Santa, T., Shintani, Y., Fujie, H., Miyoshi, H., Tsutsumi, T., Miyazawa, T., Ishibashi, K. & other authors (2001). Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis. Cancer Res 61, 4365-4370.
    • (2001) Cancer Res , vol.61 , pp. 4365-4370
    • Moriya, K.1    Nakagawa, K.2    Santa, T.3    Shintani, Y.4    Fujie, H.5    Miyoshi, H.6    Tsutsumi, T.7    Miyazawa, T.8    Ishibashi, K.9
  • 71
    • 79952712223 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species drive proinflammatory cytokine production
    • Naik, E. & Dixit, V. M. (2011). Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J Exp Med 208, 417-420.
    • (2011) J Exp Med , vol.208 , pp. 417-420
    • Naik, E.1    Dixit, V.M.2
  • 72
    • 37349065804 scopus 로고    scopus 로고
    • Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription
    • Nishina, S., Hino, K., Korenaga, M., Vecchi, C., Pietrangelo, A., Mizukami, Y., Furutani, T., Sakai, A., Okuda, M. & other authors (2008). Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription. Gastroenterology 134, 226-238.
    • (2008) Gastroenterology , vol.134 , pp. 226-238
    • Nishina, S.1    Hino, K.2    Korenaga, M.3    Vecchi, C.4    Pietrangelo, A.5    Mizukami, Y.6    Furutani, T.7    Sakai, A.8    Okuda, M.9
  • 73
    • 0036165333 scopus 로고    scopus 로고
    • Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
    • Okuda, M., Li, K., Beard, M. R., Showalter, L. A., Scholle, F., Lemon, S. M. & Weinman, S. A. (2002). Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 122, 366-375.
    • (2002) Gastroenterology , vol.122 , pp. 366-375
    • Okuda, M.1    Li, K.2    Beard, M.R.3    Showalter, L.A.4    Scholle, F.5    Lemon, S.M.6    Weinman, S.A.7
  • 75
    • 33748114343 scopus 로고    scopus 로고
    • The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
    • Perz, J. F., Armstrong, G. L., Farrington, L. A., Hutin, Y. J. & Bell, B. P. (2006). The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol 45, 529-538.
    • (2006) J Hepatol , vol.45 , pp. 529-538
    • Perz, J.F.1    Armstrong, G.L.2    Farrington, L.A.3    Hutin, Y.J.4    Bell, B.P.5
  • 76
    • 34547415672 scopus 로고    scopus 로고
    • Hepatitis C virus protein expression causes calcium-mediated mitochondrial bioenergetic dysfunction and nitro-oxidative stress
    • Piccoli, C., Scrima, R., Quarato, G., D'Aprile, A., Ripoli, M., Lecce, L., Boffoli, D., Moradpour, D. & Capitanio, N. (2007). Hepatitis C virus protein expression causes calcium-mediated mitochondrial bioenergetic dysfunction and nitro-oxidative stress. Hepatology 46, 58-65.
    • (2007) Hepatology , vol.46 , pp. 58-65
    • Piccoli, C.1    Scrima, R.2    Quarato, G.3    D'Aprile, A.4    Ripoli, M.5    Lecce, L.6    Boffoli, D.7    Moradpour, D.8    Capitanio, N.9
  • 77
    • 79952201309 scopus 로고    scopus 로고
    • Hepatitis B virus X protein impedes the DNA repair via its association with transcription factor, TFIIH
    • Qadri, I., Fatima, K. & Abdel-Hafiz, H. (2011). Hepatitis B virus X protein impedes the DNA repair via its association with transcription factor, TFIIH. BMC Microbiol 11, 48.
    • (2011) BMC Microbiol , vol.11 , pp. 48
    • Qadri, I.1    Fatima, K.2    Abdel-Hafiz, H.3
  • 79
    • 0030745912 scopus 로고    scopus 로고
    • In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in xeroderma pigmentosum patients
    • Reardon, J. T., Bessho, T., Kung, H. C., Bolton, P. H. & Sancar, A. (1997). In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients. Proc Natl Acad Sci U S A 94, 9463-9468.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9463-9468
    • Reardon, J.T.1    Bessho, T.2    Kung, H.C.3    Bolton, P.H.4    Sancar, A.5
  • 86
    • 0036172292 scopus 로고    scopus 로고
    • Insights into the pathobiology of hepatitis C virus-associated cirrhosis: Analysis of intrahepatic differential gene expression
    • Shackel, N. A., McGuinness, P. H., Abbott, C. A., Gorrell, M. D. & McCaughan, G. W. (2002). Insights into the pathobiology of hepatitis C virus-associated cirrhosis: analysis of intrahepatic differential gene expression. Am J Pathol 160, 641-654.
    • (2002) Am J Pathol , vol.160 , pp. 641-654
    • Shackel, N.A.1    McGuinness, P.H.2    Abbott, C.A.3    Gorrell, M.D.4    McCaughan, G.W.5
  • 87
    • 0038158319 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential
    • Shirakata, Y. & Koike, K. (2003). Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential. J Biol Chem 278, 22071-22078.
    • (2003) J Biol Chem , vol.278 , pp. 22071-22078
    • Shirakata, Y.1    Koike, K.2
  • 89
    • 78349244100 scopus 로고    scopus 로고
    • Hepatitis C virus-induced oxidative stress and mitochondrial dysfunction: A focus on recent advances in proteomics
    • Simula, M. P. & De Re, V. (2010). Hepatitis C virus-induced oxidative stress and mitochondrial dysfunction: a focus on recent advances in proteomics. Proteomics Clin Appl 4, 782-793.
    • (2010) Proteomics Clin Appl , vol.4 , pp. 782-793
    • Simula, M.P.1    De Re, V.2
  • 90
    • 80053951780 scopus 로고    scopus 로고
    • Antioxidants as therapeutic agents for liver disease
    • Singal, A. K., Jampana, S. C. & Weinman, S. A. (2011). Antioxidants as therapeutic agents for liver disease. Liver Int 31, 1432-1448.
    • (2011) Liver Int , vol.31 , pp. 1432-1448
    • Singal, A.K.1    Jampana, S.C.2    Weinman, S.A.3
  • 91
    • 33750344724 scopus 로고    scopus 로고
    • Different transformation pathways of murine fibroblast NIH 3T3 cells by hepatitis C virus core and NS3 proteins
    • Smirnova, I. S., Aksenov, N. D., Vonsky, M. S. & Isaguliants, M. G. (2006). Different transformation pathways of murine fibroblast NIH 3T3 cells by hepatitis C virus core and NS3 proteins. Cell Biol Int 30, 915-919.
    • (2006) Cell Biol Int , vol.30 , pp. 915-919
    • Smirnova, I.S.1    Aksenov, N.D.2    Vonsky, M.S.3    Isaguliants, M.G.4
  • 92
    • 0033604446 scopus 로고    scopus 로고
    • Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death
    • Takada, S., Shirakata, Y., Kaneniwa, N. & Koike, K. (1999). Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death. Oncogene 18, 6965-6973.
    • (1999) Oncogene , vol.18 , pp. 6965-6973
    • Takada, S.1    Shirakata, Y.2    Kaneniwa, N.3    Koike, K.4
  • 93
    • 84875932668 scopus 로고    scopus 로고
    • Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations
    • Toh, S. T., Jin, Y., Liu, L., Wang, J., Babrzadeh, F., Gharizadeh, B., Ronaghi, M., Toh, H. C., Chow, P. K. & other authors (2013). Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations. Carcinogenesis 34, 787-798.
    • (2013) Carcinogenesis , vol.34 , pp. 787-798
    • Toh, S.T.1    Jin, Y.2    Liu, L.3    Wang, J.4    Babrzadeh, F.5    Gharizadeh, B.6    Ronaghi, M.7    Toh, H.C.8    Chow, P.K.9
  • 94
    • 0036285034 scopus 로고    scopus 로고
    • c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
    • Vafa, O., Wade, M., Kern, S., Beeche, M., Pandita, T. K., Hampton, G. M. & Wahl, G. M. (2002). c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell 9, 1031-1044.
    • (2002) Mol Cell , vol.9 , pp. 1031-1044
    • Vafa, O.1    Wade, M.2    Kern, S.3    Beeche, M.4    Pandita, T.K.5    Hampton, G.M.6    Wahl, G.M.7
  • 95
    • 84869066771 scopus 로고    scopus 로고
    • The hepatitis B virus x protein inhibits thymine DNA glycosylase initiated base excision repair
    • van de Klundert, M. A., van Hemert, F. J., Zaaijer, H. L. & Kootstra, N. A. (2012). The hepatitis B virus x protein inhibits thymine DNA glycosylase initiated base excision repair. PLoS ONE 7, e48940.
    • (2012) PLoS ONE , vol.7
    • van de Klundert, M.A.1    van Hemert, F.J.2    Zaaijer, H.L.3    Kootstra, N.A.4
  • 96
    • 84655169936 scopus 로고    scopus 로고
    • Tumor suppressor genes and ROS: Complex networks of interactions
    • Vurusaner, B., Poli, G. & Basaga, H. (2012). Tumor suppressor genes and ROS: complex networks of interactions. Free Radic Biol Med 52, 7-18.
    • (2012) Free Radic Biol Med , vol.52 , pp. 7-18
    • Vurusaner, B.1    Poli, G.2    Basaga, H.3
  • 97
    • 33747600880 scopus 로고    scopus 로고
    • Causes and consequences of mitochondrial reactive oxygen species generation in hepatitis C
    • Wang, T. & Weinman, S. A. (2006). Causes and consequences of mitochondrial reactive oxygen species generation in hepatitis C. J Gastroenterol Hepatol 21 (Suppl 3), S34-S37.
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.SUPPL. 3
    • Wang, T.1    Weinman, S.A.2
  • 98
    • 84896844772 scopus 로고    scopus 로고
    • Interactions between hepatitis C virus and mitochondria: Impact on pathogenesis and innate immunity
    • Wang, T. & Weinman, S. A. (2013). Interactions between hepatitis C virus and mitochondria: impact on pathogenesis and innate immunity. Curr Pathobiol Rep 1, 179-187.
    • (2013) Curr Pathobiol Rep , vol.1 , pp. 179-187
    • Wang, T.1    Weinman, S.A.2
  • 99
    • 0001655748 scopus 로고
    • Hepatitis B virus X protein inhibits p53 sequencespecific DNA binding, transcriptional activity, and association with transcription factor ERCC3
    • Wang, X. W., Forrester, K., Yeh, H., Feitelson, M. A., Gu, J. R. & Harris, C. C. (1994). Hepatitis B virus X protein inhibits p53 sequencespecific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc Natl Acad Sci U S A 91, 2230-2234.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 2230-2234
    • Wang, X.W.1    Forrester, K.2    Yeh, H.3    Feitelson, M.A.4    Gu, J.R.5    Harris, C.C.6
  • 100
    • 16244375544 scopus 로고    scopus 로고
    • Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes
    • Wang, H. C., Chang, W. T., Chang, W. W., Wu, H. C., Huang, W., Lei, H. Y., Lai, M. D., Fausto, N. & Su, I. J. (2005). Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology 41, 761-770.
    • (2005) Hepatology , vol.41 , pp. 761-770
    • Wang, H.C.1    Chang, W.T.2    Chang, W.W.3    Wu, H.C.4    Huang, W.5    Lei, H.Y.6    Lai, M.D.7    Fausto, N.8    Su, I.J.9
  • 101
    • 70349095986 scopus 로고    scopus 로고
    • Nonstructural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice
    • Wang, A. G., Lee, D. S., Moon, H. B., Kim, J. M., Cho, K. H., Choi, S. H., Ha, H. L., Han, Y. H., Kim, D. G. & other authors (2009). Nonstructural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. J Pathol 219, 253-262.
    • (2009) J Pathol , vol.219 , pp. 253-262
    • Wang, A.G.1    Lee, D.S.2    Moon, H.B.3    Kim, J.M.4    Cho, K.H.5    Choi, S.H.6    Ha, H.L.7    Han, Y.H.8    Kim, D.G.9
  • 102
    • 80052512520 scopus 로고    scopus 로고
    • Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair
    • Woodbine, L., Brunton, H., Goodarzi, A. A., Shibata, A. & Jeggo, P. A. (2011). Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair. Nucleic Acids Res 39, 6986-6997.
    • (2011) Nucleic Acids Res , vol.39 , pp. 6986-6997
    • Woodbine, L.1    Brunton, H.2    Goodarzi, A.A.3    Shibata, A.4    Jeggo, P.A.5
  • 103
    • 0036290134 scopus 로고    scopus 로고
    • Subcellular localization of HCV core protein regulates its ability for p53 activation and p21 suppression
    • Yamanaka, T., Kodama, T. & Doi, T. (2002). Subcellular localization of HCV core protein regulates its ability for p53 activation and p21 suppression. Biochem Biophys Res Commun 294, 528-534.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 528-534
    • Yamanaka, T.1    Kodama, T.2    Doi, T.3
  • 104
    • 0034718770 scopus 로고    scopus 로고
    • Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells
    • Yun, C., Lee, J. H., Park, H., Jin, Y. M., Park, S., Park, K. & Cho, H. (2000). Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells. Oncogene 19, 5163-5172.
    • (2000) Oncogene , vol.19 , pp. 5163-5172
    • Yun, C.1    Lee, J.H.2    Park, H.3    Jin, Y.M.4    Park, S.5    Park, K.6    Cho, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.