Cellular microRNAs (miRNAs) and Sjögren's syndrome: Candidate regulators of autoimmune response and autoantigen expression

Journal of Autoimmunity

Volumn 37, Issue 2, 2011, Pages 129-135

  Kapsogeorgou, Efstathia K ^a   Gourzi, Vasiliki C ^a   Manoussakis, Menelaos N ^a   Moutsopoulos, Haralampos M ^a   Tzioufas, Athanasios G ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Autoimmune diseases; MicroRNAs; Ro SSA and La SSB autoantigens; Sj gren's syndrome

Indexed keywords

AUTOANTIGEN; DICER; MICRORNA; RIBONUCLEOPROTEIN;

ANGIOGENESIS; ANTIGEN EXPRESSION; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DOWN REGULATION; ENTERITIS; HUMAN; HUMORAL IMMUNITY; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNE RESPONSE; MULTIPLE SCLEROSIS; NONHUMAN; ONTOGENY; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PSORIASIS; REGULATORY T LYMPHOCYTE; REVIEW; RHEUMATOID ARTHRITIS; SALIVARY GLAND; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; UPREGULATION;

ANIMALS; AUTOANTIGENS; AUTOIMMUNITY; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MICROARRAY ANALYSIS; MICRORNAS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBONUCLEOPROTEINS; RNA, SMALL CYTOPLASMIC; SALIVARY GLANDS; SJOGREN'S SYNDROME;

EID: 80052658474     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2011.05.003     Document Type: Review

References (64)

1. Tzioufas A.G., Voulgarelis M. Update on Sjögren's syndrome autoimmune epithelitis: from classification to increased neoplasias. Best Pract Res Clin Rheumatol 2007, 21:989-1010.
2. Manoussakis M.N., Kapsogeorgou E.K. The role of intrinsic epithelial activation in the pathogenesis of Sjögren's syndrome. J Autoimmun 2010, 35:219-224.
3. Routsias J.G., Tzioufas A.G. Sjögren's syndrome - study of autoantigens and autoantibodies. Clin Rev Allergy Immunol 2007, 32:238-251.
4. Horsfall A.C., Rose L.M., Maini R.N. Autoantibody synthesis in salivary glands of Sjögren's syndrome patients. J Autoimmun 1989, 2:559-568.
5. Salomonsson S., Wahren-Herlenius M. Local production of Ro/SSA and La/SSB autoantibodies in the target organ coincides with high levels of circulating antibodies in sera of patients with Sjögren's syndrome. Scand J Rheumatol 2003, 32:79-82.
6. Yannopoulos D.I., Roncin S., Lamour A., Pennec Y.L., Moutsopoulos H.M., Youinou P. Conjunctival epithelial cells from patients with Sjögren's syndrome inappropriately express major histocompatibility complex molecules, La(SSB) antigen, and heat-shock proteins. J Clin Immunol 1992, 12:259-265.
7. Rosen A., Casciola-Rosen L., Ahearn J. Novel packages of viral and self-antigens are generated during apoptosis. J Exp Med 1995, 181:1557-1561.
8. Kapsogeorgou E.K., Abu-Helu R.F., Moutsopoulos H.M., Manoussakis M.N. Salivary gland epithelial cell exosomes: a source of autoantigenic ribonucleoproteins. Arthritis Rheum 2005, 52:1517-1521.
9. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
10. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
11. Baltimore D., Boldin M.P., O'Connell R.M., Rao D.S., Taganov K.D. MicroRNAs: new regulators of immune cell development and function. Nat Immunol 2008, 9:839-845.
12. Hoefig K.P., Heissmeyer V. MicroRNAs grow up in the immune system. Curr Opin Immunol 2008, 20:281-287.
13. Bhanji R.A., Eystathioy T., Chan E.K., Bloch D.B., Fritzler M.J. Clinical and serological features of patients with autoantibodies to GW/P bodies. Clin Immunol 2007, 125:247-256.
14. Iborra M, Bernuzzi F, Invernizzi P, Danese S. MicroRNAs in autoimmunity and inflammatory bowel disease: crucial regulators in immune response. Autoimmun Rev. 2010 (Epub ahead of print).
15. O'Connell R.M., Rao D.S., Chaudhuri A.A., Baltimore D. Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 2010, 10:111-122.
16. Obernosterer G., Leuschner P.J., Alenius M., Martinez J. Post-transcriptional regulation of microRNA expression. RNA 2006, 12:1161-1167.
17. Bernstein E., Kim S.Y., Carmell M.A., Murchison E.P., Alcorn H., Li M.Z., et al. Dicer is essential for mouse development. Nat Genet 2003, 35:215-217.
18. Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
19. Kloosterman W.P., Lagendijk A.K., Ketting R.F., Moulton J.D., Plasterk R.H. Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol 2007, 5:e203.
20. Cheng Y., Ji R., Yue J., Yang J., Liu X., Chen H., et al. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy?. Am J Pathol 2007, 170:1831-1840.
21. Hansen T., Olsen L., Lindow M., Jakobsen K.D., Ullum H., Jonsson E., et al. Brain expressed microRNAs implicated in schizophrenia etiology. PLoS One 2007, 2:e873.
22. Tufekci K.U., Oner M.G., Genc S., Genc K. MicroRNAs and multiple Sclerosis. Autoimmune Dis 2011, 807426.
23. Alevizos I., Illei G.G. MicroRNAs in Sjogren's syndrome as a prototypic autoimmune disease. Autoimmun Rev 2010, 9:618-621.
24. Wiesen J.L., Tomasi T.B. Dicer is regulated by cellular stresses and interferons. Mol Immunol 2009, 46:1222-1228.
25. Cobb B.S., Hertweck A., Smith J., O'Connor E., Graf D., Cook T., et al. A role for Dicer in immune regulation. J Exp Med 2006, 203:2519-2527.
26. Satoh M., Langdon J.J., Chou C.H., McCauliffe D.P., Treadwell E.L., Ogasawara T., et al. Characterization of the Su antigen, a macromolecular complex of 100/102 and 200-kDa proteins recognized by autoantibodies in systemic rheumatic diseases. Clin Immunol Immunopathol 1994, 73:132-141.
27. Jakymiw A., Ikeda K., Fritzler M.J., Reeves W.H., Satoh M., Chan E.K. Autoimmune targeting of key components of RNA interference. Arthritis Res Ther 2006, 8:R87.
28. Furer V., Greenberg J.D., Attur M., Abramson S.B., Pillinger M.H. The role of microRNA in rheumatoid arthritis and other autoimmune diseases. Clin Immunol 2010, 136:1-15.
29. Carissimi C., Fulci V., Macino G. MicroRNAs: novel regulators of immunity. Autoimmun Rev 2009, 8:520-524.
30. Pauley K.M., Cha S., Chan E.K. MicroRNA in autoimmunity and autoimmune diseases. J Autoimmun 2009, 32:189-194.
31. Alevizos I., Alexander S., Turner R.J., Illei G.G. MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome. Arthritis Rheum 2011, 63:535-544.
32. Michael A., Bajracharya S.D., Yuen P.S., Zhou H., Star R.A., Illei G.G., et al. Exosomes from human saliva as a source of microRNA biomarkers. Oral Dis 2010, 16:34-38.
33. Dimitriou I.D., Kapsogeorgou E.K., Abu-Helu R.F., Moutsopoulos H.M., Manoussakis M.N. Establishment of a convenient system for the long-term culture and study of non-neoplastic human salivary gland epithelial cells. Eur J Oral Sci 2002, 110:21-30.
34. Zhao X., Tang Y., Qu B., Cui H., Wang S., Wang L., et al. MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus. Arthritis Rheum 2010, 62:3425-3435.
35. Zhao S., Wang Y., Liang Y., Zhao M., Long H., Ding S., et al. MicroRNA-126 regulates DNA methylation in CD4(+) T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. Arthritis Rheum 2011, 63:1376-1386.
36. Pan W., Zhu S., Yuan M., Cui H., Wang L., Luo X., et al. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol 2010, 184:6773-6781.
37. Tang Y., Luo X., Cui H., Ni X., Yuan M., Guo Y., et al. MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum 2009, 60:1065-1075.
38. Dai Y., Huang Y.S., Tang M., Lv T.Y., Hu C.X., Tan Y.H., et al. Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus 2007, 16:939-946.
39. Te J.L., Dozmorov I.M., Guthridge J.M., Nguyen K.L., Cavett J.W., Kelly J.A., et al. Identification of unique microRNA signature associated with lupus nephritis. PLoS One 2010, 5:e10344.
40. Sonkoly E., Wei T., Janson P.C., Saaf A., Lundeberg L., Tengvall-Linder M., et al. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?. PLoS One 2007, 2:e610.
41. Padgett K.A., Lan R.Y., Leung P.C., Lleo A., Dawson K., Pfeiff J., et al. Primary biliary cirrhosis is associated with altered hepatic microRNA expression. J Autoimmun 2009, 32:246-253.
42. Witwer K.W., Sisk J.M., Gama L., Clements J.E. MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response. J Immunol 2010, 184:2369-2376.
43. Pedersen I., David M. MicroRNAs in the immune response. Cytokine 2008, 43:391-394.
44. Liu L, Chen R, Huang S, Wu Y, Li G, Zhang B et al. miR-153 sensitized the K562 cells to As2O3-induced apoptosis. Med Oncol. 2011 (Epub ahead of print).
45. Vitali C., Bombardieri S., Jonsson R., Moutsopoulos H.M., Alexander E.L., Carsons S.E., et al. Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002, 61:554-558.
46. Youinou P. Haralampos M. Moutsopoulos: a lifetime in autoimmunity. J Autoimmun 2010, 35:171-175.
47. Juran B.D., Lazaridis K.N. Update on the genetics and genomics of PBC. J Autoimmun 2010, 35:181-187.
48. Miyagawa F., Gutermuth J., Zhang H., Katz S.I. The use of mouse models to better understand mechanisms of autoimmunity and tolerance. J Autoimmun 2010, 35:192-198.
49. Kontaki E., Boumpas D.T. Innate immunity in systemic lupus erythematosus: sensing endogenous nucleic acids. J Autoimmun 2010, 35:206-211.
50. Wiik A.S., Hoier-Madsen M., Forslid J., Charles P., Meyrowitsch J. Antinuclear antibodies: a contemporary nomenclature using HEp-2 cells. J Autoimmun 2010, 35:276-290.
51. Youinou P., Pers J.-O. The international symposium on Sjogren's syndrome in Brest: the "top of the tops" at the "tip of the tips" J Autoimmun 2010, 35:589-590.
52. Lu Q., Renaudineau Y., Cha S., Ilei G., Brooks W.H., Selmi C., et al. Epigenetics in autoimmune disorders: highlights of the 10th Sjogren's syndrome symposium. J Autoimmun 2010, 35:627-630.
53. Youinou P., Pers J.-O., Gershwin M.E., Shoenfeld Y. Geo-epidemiology and autoimmunity. J Autoimmun 2010, 34:J163-J167.
54. Shapira Y., Agmon-Levin N., Shoenfeld Y. Defining and analyzing geoepidemiology and human autoimmunity. J Autoimmun 2010, 34:J168-J177.
55. Chang C. The immune effects of naturally occurring and synthetic nanoparticles. J Autoimmun 2010, 34:J234-J246.
56. Chang C., Gershwin M.E. Drugs and autoimmunity - a contemporary review and mechanistic approach. J Autoimmun 2010, 34:J266-J275.
57. Meroni P.L., Shoenfeld Y. Systemic lupus erythematosus and the SLE galaxy. Autoimmun Rev 2010, 10:1-2.
58. Gualtierotti R., Biggioggero M., Penatti A.E., Meroni P.L. Updating on the pathogenesis of systemic lupus erythematosus. Autoimmun Rev 2010, 10:3-7.
59. Kelley J.M., Edberg J.C., Kimberly R.P. Pathways: strategies for susceptibility genes in SLE. Autoimun Rev 2010, 9:473-476.
60. Ansari A.A., Gershwin M.E. Navigating the passage between Charybdis and Scylla: recognizing the achievements of Noel Rose. J Autoimmun 2009, 33:165-169.
61. Mackay I.R. Clustering and commonalities among autoimmune diseases. J Autoimmun 2009, 33:170-177.
62. Chiorini J.A., Cihakova D., Oullette C.E., Caturegli P. Sjogren syndrome: advances in the pathogenesis from animal models. J Autoimmun 2009, 33:190-196.
63. Cooper G.S., Bynum M.L.K., Somers E.C. Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases. J Autoimun 2009, 33:197-207.
64. Invernizzi P., Gershwin M.E. The genetics of human autoimmune disease. J Autoimmun 2009, 33:290-299.