-
1
-
-
0037112366
-
Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: Magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin
-
Dafni, H., Israely, T., Bhujwalla, Z. M., Benjamin, L. E. & Neeman, M. Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin. Cancer Res. 62, 6731-6739 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 6731-6739
-
-
Dafni, H.1
Israely, T.2
Bhujwalla, Z.M.3
Benjamin, L.E.4
Neeman, M.5
-
2
-
-
33947494918
-
Tumorinduced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis
-
Harrell, M. I., Iritani, B. M. & Ruddell, A. Tumorinduced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. Am. J. Pathol. 170, 774-786 (2007).
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 774-786
-
-
Harrell, M.I.1
Iritani, B.M.2
Ruddell, A.3
-
3
-
-
84857573201
-
Sentinel lymph node lymphangiogenesis and increased lymph flow in murine tumor metastasis
-
Ruddell, A., Harrell, M. I. & Furuya, M. Sentinel lymph node lymphangiogenesis and increased lymph flow in murine tumor metastasis. Clin. Exp. Metast. 26, 883-884 (2009).
-
(2009)
Clin. Exp. Metast.
, vol.26
, pp. 883-884
-
-
Ruddell, A.1
Harrell, M.I.2
Furuya, M.3
-
4
-
-
33744910853
-
Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotype
-
Pathak, A. P., Artemov, D., Neeman, M. & Bhujwalla, Z. M. Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotype. Cancer Res. 66, 5151-5158 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 5151-5158
-
-
Pathak, A.P.1
Artemov, D.2
Neeman, M.3
Bhujwalla, Z.M.4
-
5
-
-
0020083795
-
Interstitial fluid pressure in DMBA-induced rat mammary tumours
-
Wiig, H., Tveit, E., Hultborn, R., Reed, R. K. & Weiss, L. Interstitial fluid pressure in DMBA-induced rat mammary tumours. Scand. J. Clin. Lab. Invest. 42, 159-164 (1982).
-
(1982)
Scand. J. Clin. Lab. Invest.
, vol.42
, pp. 159-164
-
-
Wiig, H.1
Tveit, E.2
Hultborn, R.3
Reed, R.K.4
Weiss, L.5
-
6
-
-
17144417329
-
Resistance of tumor interstitial pressure to the penetration of intraperitoneally delivered antibodies into metastatic ovarian tumors
-
Flessner, M. F., Choi, J., Credit, K., Deverkadra, R. & Henderson, K. Resistance of tumor interstitial pressure to the penetration of intraperitoneally delivered antibodies into metastatic ovarian tumors. Clin. Cancer Res. 11, 3117-3125 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3117-3125
-
-
Flessner, M.F.1
Choi, J.2
Credit, K.3
Deverkadra, R.4
Henderson, K.5
-
7
-
-
34247394267
-
Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix
-
Pedersen, J. A., Boschetti, F. & Swartz, M. A. Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix. J. Biomech. 40, 1484-1492 (2007).
-
(2007)
J. Biomech.
, vol.40
, pp. 1484-1492
-
-
Pedersen, J.A.1
Boschetti, F.2
Swartz, M.A.3
-
8
-
-
38949135155
-
The microanatomy of T-cell responses
-
Lammermann, T. & Sixt, M. The microanatomy of T-cell responses. Immunol. Rev. 221, 26-43 (2008).
-
(2008)
Immunol. Rev.
, vol.221
, pp. 26-43
-
-
Lammermann, T.1
Sixt, M.2
-
9
-
-
0034693949
-
Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex
-
Gretz, J. E., Norbury, C. C., Anderson, A. O., Proudfoot, A. E. & Shaw, S. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 192, 1425-1440 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1425-1440
-
-
Gretz, J.E.1
Norbury, C.C.2
Anderson, A.O.3
Proudfoot, A.E.4
Shaw, S.5
-
10
-
-
0016824929
-
Bulk transfer of fluid in interstitial compartment of mammary tumors
-
Butler, T. P., Grantham, F. H. & Gullino, P. M. Bulk transfer of fluid in interstitial compartment of mammary tumors. Cancer Res. 35, 3084-3088 (1975).
-
(1975)
Cancer Res.
, vol.35
, pp. 3084-3088
-
-
Butler, T.P.1
Grantham, F.H.2
Gullino, P.M.3
-
11
-
-
34447258681
-
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
-
Fukumura, D. & Jain, R. K. Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J. Cell. Biochem. 101, 937-949 (2007).
-
(2007)
J. Cell. Biochem.
, vol.101
, pp. 937-949
-
-
Fukumura, D.1
Jain, R.K.2
-
12
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
79955441991
-
Balancing forces: Architectural control of mechanotransduction
-
Dufort, C. C., Paszek, M. J. & Weaver, V. M. Balancing forces: architectural control of mechanotransduction. Nature Rev. Mol. Cell Biol. 12, 308-319 (2011).
-
(2011)
Nature Rev. Mol. Cell Biol.
, vol.12
, pp. 308-319
-
-
Dufort, C.C.1
Paszek, M.J.2
Weaver, V.M.3
-
14
-
-
68549085276
-
Tissue architecture and function: Dynamic reciprocity via extra-and intracellular matrices
-
Xu, R., Boudreau, A. & Bissell, M. Tissue architecture and function: dynamic reciprocity via extra-and intracellular matrices. Cancer Metastasis Rev. 28, 167-176 (2009).
-
(2009)
Cancer Metastasis Rev.
, vol.28
, pp. 167-176
-
-
Xu, R.1
Boudreau, A.2
Bissell, M.3
-
15
-
-
4944266313
-
High interstitial fluid pressure - An obstacle in cancer therapy
-
Heldin, C. H., Rubin, K., Pietras, K. & Ostman, A. High interstitial fluid pressure - an obstacle in cancer therapy. Nature Rev. Cancer 4, 806-813 (2004).
-
(2004)
Nature Rev. Cancer
, vol.4
, pp. 806-813
-
-
Heldin, C.H.1
Rubin, K.2
Pietras, K.3
Ostman, A.4
-
16
-
-
0024991704
-
Evaluation of methodologies for measurement of interstitial fluid pressure (Pi): Physiological implications of recent Pi data
-
Wiig, H. Evaluation of methodologies for measurement of interstitial fluid pressure (Pi): physiological implications of recent Pi data. Crit. Rev. Biomed. Eng. 18, 27-54 (1990).
-
(1990)
Crit. Rev. Biomed. Eng.
, vol.18
, pp. 27-54
-
-
Wiig, H.1
-
17
-
-
0029787909
-
Tumor angiogenesis and interstitial hypertension
-
Boucher, Y., Leunig, M. & Jain, R. K. Tumor angiogenesis and interstitial hypertension. Cancer Res. 56, 4264-4266 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 4264-4266
-
-
Boucher, Y.1
Leunig, M.2
Jain, R.K.3
-
18
-
-
41149138113
-
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer
-
Jain, R. K. Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer. Nature Rev. Cancer 8, 309-316 (2008).
-
(2008)
Nature Rev. Cancer
, vol.8
, pp. 309-316
-
-
Jain, R.K.1
-
19
-
-
77956925182
-
Quantitative imaging of lymphatic function with liposomal indocyanine green
-
Proulx, S. T. et al. Quantitative imaging of lymphatic function with liposomal indocyanine green. Cancer Res. 70, 7053-7062 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 7053-7062
-
-
Proulx, S.T.1
-
20
-
-
73549105244
-
+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm
-
+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm. Am. J. Pathol. 175, 1733-1745 (2009).
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 1733-1745
-
-
Kim, K.E.1
-
21
-
-
67049167170
-
+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution
-
+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution. Blood 113, 5650-5659 (2009).
-
(2009)
Blood
, vol.113
, pp. 5650-5659
-
-
Kataru, R.P.1
-
22
-
-
75649083174
-
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-κB and Prox1
-
Flister, M. J. et al. Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-κB and Prox1. Blood 115, 418-429 (2009).
-
(2009)
Blood
, vol.115
, pp. 418-429
-
-
Flister, M.J.1
-
23
-
-
69449085032
-
Lymphangiogenesis, myeloid cells and inflammation
-
Xing, L. P. & Ji, R. C. Lymphangiogenesis, myeloid cells and inflammation. Exp. Rev. Clin. Immunol. 4, 599-613 (2008).
-
(2008)
Exp. Rev. Clin. Immunol.
, vol.4
, pp. 599-613
-
-
Xing, L.P.1
Ji, R.C.2
-
24
-
-
36148936760
-
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes
-
Halin, C., Tobler, N. E., Vigl, B., Brown, L. F. & Detmar, M. VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes. Blood 110, 3158-3167 (2007).
-
(2007)
Blood
, vol.110
, pp. 3158-3167
-
-
Halin, C.1
Tobler, N.E.2
Vigl, B.3
Brown, L.F.4
Detmar, M.5
-
25
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
Tammela, T. & Alitalo, K. Lymphangiogenesis: molecular mechanisms and future promise. Cell 140, 460-476 (2010).
-
(2010)
Cell
, vol.140
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
26
-
-
79957879861
-
Lymphangiogenesis in post-natal tissue remodeling: Lymphatic endothelial cell connection with its environment
-
Paupert, J., Sounni, N. E. & Noel, A. Lymphangiogenesis in post-natal tissue remodeling: lymphatic endothelial cell connection with its environment. Mol. Aspects Med. 32, 146-158 (2011).
-
(2011)
Mol. Aspects Med.
, vol.32
, pp. 146-158
-
-
Paupert, J.1
Sounni, N.E.2
Noel, A.3
-
27
-
-
47949114114
-
Integrins in angiogenesis and lymphangiogenesis
-
Avraamides, C. J., Garmy-Susini, B. & Varner, J. A. Integrins in angiogenesis and lymphangiogenesis. Nature Rev. Cancer 8, 604-617 (2008).
-
(2008)
Nature Rev. Cancer
, vol.8
, pp. 604-617
-
-
Avraamides, C.J.1
Garmy-Susini, B.2
Varner, J.A.3
-
28
-
-
0034842967
-
Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma
-
Skobe, M. et al. Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma. Am. J. Pathol. 159, 893-903 (2001).
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 893-903
-
-
Skobe, M.1
-
29
-
-
70349330902
-
Lymphangiogenesis and cancer metastasis
-
Mumprecht, V. & Detmar, M. Lymphangiogenesis and cancer metastasis. J. Cell. Mol. Med. 13, 1405-1416 (2009).
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 1405-1416
-
-
Mumprecht, V.1
Detmar, M.2
-
30
-
-
45849114674
-
Dynamic contrast-enhanced magnetic resonance imaging of tumor-induced lymph flow
-
Ruddell, A. et al. Dynamic contrast-enhanced magnetic resonance imaging of tumor-induced lymph flow. Neoplasia 10, 706-713 (2008).
-
(2008)
Neoplasia
, vol.10
, pp. 706-713
-
-
Ruddell, A.1
-
31
-
-
0016762843
-
Types of reaction in the regional lymph nodes in non-metastatic and minute-metastatic carcinoma of the uterine cervix
-
Kozlowski, H. & Hrabowska, M. Types of reaction in the regional lymph nodes in non-metastatic and minute-metastatic carcinoma of the uterine cervix. Arch. Geschwulstforsch. 45, 658-659 (1975).
-
(1975)
Arch. Geschwulstforsch.
, vol.45
, pp. 658-659
-
-
Kozlowski, H.1
Hrabowska, M.2
-
32
-
-
0037453703
-
Interstitial flow as a guide for lymphangiogenesis
-
Boardman, K. C. & Swartz, M. A. Interstitial flow as a guide for lymphangiogenesis. Circ. Res. 92, 801-808 (2003).
-
(2003)
Circ. Res.
, vol.92
, pp. 801-808
-
-
Boardman, K.C.1
Swartz, M.A.2
-
33
-
-
14244251166
-
Interstitial flow differentially stimulates blood and lymphatic endothelial cell morphogenesis in vitro
-
Ng, C. P., Helm, C. L. & Swartz, M. A. Interstitial flow differentially stimulates blood and lymphatic endothelial cell morphogenesis in vitro. Microvasc. Res. 68, 258-264 (2004).
-
(2004)
Microvasc. Res.
, vol.68
, pp. 258-264
-
-
Ng, C.P.1
Helm, C.L.2
Swartz, M.A.3
-
34
-
-
27644453468
-
Synergy between 3D flow and VEGF directs capillary morphogenesis in vitro: Experiments and theoretical mechanisms
-
Helm, C. E., Fleury, M. E., Zisch, A. H., Boschetti, F. & Swartz, M. A. Synergy between 3D flow and VEGF directs capillary morphogenesis in vitro: experiments and theoretical mechanisms. Proc. Natl Acad. Sci. USA 44, 15779-15784 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.44
, pp. 15779-15784
-
-
Helm, C.E.1
Fleury, M.E.2
Zisch, A.H.3
Boschetti, F.4
Swartz, M.A.5
-
35
-
-
78649450413
-
Interaction between the extracellular matrix and lymphatics: Consequences for lymphangiogenesis and lymphatic function
-
Wiig, H., Keskin, D. & Kalluri, R. Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biol. 29, 645-656 (2010).
-
(2010)
Matrix Biol.
, vol.29
, pp. 645-656
-
-
Wiig, H.1
Keskin, D.2
Kalluri, R.3
-
36
-
-
0036733564
-
Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis
-
Schoppmann, S. F. et al. Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis. Am. J. Pathol. 161, 947-956 (2002).
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 947-956
-
-
Schoppmann, S.F.1
-
37
-
-
38749101666
-
High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight
-
Raju, B., Haug, S. R., Ibrahim, S. O. & Heyeraas, K. J. High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight. J. Oral Pathol. Med. 37, 137-144 (2008).
-
(2008)
J. Oral Pathol. Med.
, vol.37
, pp. 137-144
-
-
Raju, B.1
Haug, S.R.2
Ibrahim, S.O.3
Heyeraas, K.J.4
-
38
-
-
79551565642
-
Tumor cell invasion is promoted by interstitial flowinduced matrix priming by stromal fibroblasts
-
Shieh, A., Rozansky, H., Hinz, B. & Swartz, M. A. Tumor cell invasion is promoted by interstitial flowinduced matrix priming by stromal fibroblasts. Cancer Res. 71, 790-800 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 790-800
-
-
Shieh, A.1
Rozansky, H.2
Hinz, B.3
Swartz, M.A.4
-
39
-
-
34249774277
-
Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling
-
Shields, J. D. et al. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell 11, 526-538 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 526-538
-
-
Shields, J.D.1
-
40
-
-
27844457560
-
Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro
-
Ng, C. P., Hinz, B. & Swartz, M. A. Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro. J. Cell Sci. 118, 4731-4739 (2005).
-
(2005)
J. Cell Sci.
, vol.118
, pp. 4731-4739
-
-
Ng, C.P.1
Hinz, B.2
Swartz, M.A.3
-
41
-
-
79960608623
-
Interstitial flow influences direction of tumor cell migration through competing mechanisms
-
Polacheck, W. J., Charest, J. L. & Kamm, R. D. Interstitial flow influences direction of tumor cell migration through competing mechanisms. Proc. Natl Acad. Sci. USA 108, 11115-11120 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 11115-11120
-
-
Polacheck, W.J.1
Charest, J.L.2
Kamm, R.D.3
-
42
-
-
0024373052
-
Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching
-
Chary, S. R. & Jain, R. K. Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching. Proc. Natl Acad. Sci. USA 86, 5385-5389 (1989).
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 5385-5389
-
-
Chary, S.R.1
Jain, R.K.2
-
43
-
-
67749140074
-
Non-linear elasticity of extracellular matrices enables contractile cells to communicate local position and orientation
-
Winer, J. P., Oake, S. & Janmey, P. A. Non-linear elasticity of extracellular matrices enables contractile cells to communicate local position and orientation. PLoS ONE 4, e6382 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Winer, J.P.1
Oake, S.2
Janmey, P.A.3
-
44
-
-
37249044357
-
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
-
Wipff, P. J., Rifkin, D. B., Meister, J. J. & Hinz, B. Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix. J. Cell Biol. 179, 1311-1323 (2007).
-
(2007)
J. Cell Biol.
, vol.179
, pp. 1311-1323
-
-
Wipff, P.J.1
Rifkin, D.B.2
Meister, J.J.3
Hinz, B.4
-
45
-
-
55749109860
-
In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-β1
-
Ahamed, J. et al. In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-β1. Blood 112, 3650-3660 (2008).
-
(2008)
Blood
, vol.112
, pp. 3650-3660
-
-
Ahamed, J.1
-
46
-
-
78650552589
-
Forcing form and function: Biomechanical regulation of tumor evolution
-
Yu, H. M., Mouw, J. K. & Weaver, V. M. Forcing form and function: biomechanical regulation of tumor evolution. Trends Cell Biol. 21, 47-56 (2011).
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 47-56
-
-
Yu, H.M.1
Mouw, J.K.2
Weaver, V.M.3
-
47
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek, M. J. et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 8, 241-254 (2005).
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
-
48
-
-
44149123099
-
Collagen density promotes mammary tumor initiation and progression
-
Provenzano, P. P. et al. Collagen density promotes mammary tumor initiation and progression. BMC Med. 6, 11 (2008).
-
(2008)
BMC Med.
, vol.6
, pp. 11
-
-
Provenzano, P.P.1
-
49
-
-
58149481287
-
Breast cancer by proxy: Can the microenvironment be both the cause and consequence?
-
Ronnov-Jessen, L. & Bissell, M. J. Breast cancer by proxy: can the microenvironment be both the cause and consequence? Trends Mol. Med. 15, 5-13 (2009).
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 5-13
-
-
Ronnov-Jessen, L.1
Bissell, M.J.2
-
50
-
-
79952747743
-
Aligned collagen is a prognostic signature for survival in human breast carcinoma
-
Conklin, M. W. et al. Aligned collagen is a prognostic signature for survival in human breast carcinoma. Am. J. Pathol. 178, 1221-1232 (2011).
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 1221-1232
-
-
Conklin, M.W.1
-
51
-
-
77954563464
-
Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
-
Finger, E. C. & Giaccia, A. J. Hypoxia, inflammation, and the tumor microenvironment in metastatic disease. Cancer Met. Rev. 29, 285-293 (2010).
-
(2010)
Cancer Met. Rev.
, vol.29
, pp. 285-293
-
-
Finger, E.C.1
Giaccia, A.J.2
-
52
-
-
80053586273
-
Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells
-
Guadall, A. et al. Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells. Frontiers Biosci. 3, 955-967 (2011).
-
(2011)
Frontiers Biosci.
, vol.3
, pp. 955-967
-
-
Guadall, A.1
-
53
-
-
38449113509
-
Lysyl oxidase and endothelial dysfunction: Mechanisms of lysyl oxidase downregulation by pro-inflammatory cytokines
-
Alcudia, J. F. et al. Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase downregulation by pro-inflammatory cytokines. Frontiers Biosci. 13, 2721-2727 (2008).
-
(2008)
Frontiers Biosci.
, vol.13
, pp. 2721-2727
-
-
Alcudia, J.F.1
-
54
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
Levental, K. R. et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139, 891-906 (2009).
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
-
56
-
-
79959947008
-
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
-
Goetz, J. G. et al. Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. Cell 146, 148-163 (2011).
-
(2011)
Cell
, vol.146
, pp. 148-163
-
-
Goetz, J.G.1
-
57
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
Gaggioli, C. et al. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nature Cell Biol. 9, 1392-1400 (2007).
-
(2007)
Nature Cell Biol.
, vol.9
, pp. 1392-1400
-
-
Gaggioli, C.1
-
58
-
-
78149279268
-
Determinants of leader cells in collective cell migration
-
Khalil, A. A. & Friedl, P. Determinants of leader cells in collective cell migration. Integr. Biol. 2, 568-574 (2010).
-
(2010)
Integr. Biol.
, vol.2
, pp. 568-574
-
-
Khalil, A.A.1
Friedl, P.2
-
59
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo, A. et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348 (2005).
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
-
60
-
-
33846782878
-
Collagen reorganization at the tumor-stromal interface facilitates local invasion
-
Provenzano, P. P. et al. Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med. 4, 38 (2006).
-
(2006)
BMC Med.
, vol.4
, pp. 38
-
-
Provenzano, P.P.1
-
61
-
-
67649528138
-
Collective cell migration in morphogenesis, regeneration and cancer
-
Friedl, P. & Gilmour, D. Collective cell migration in morphogenesis, regeneration and cancer. Nature Rev. Mol. Cell Biol. 10, 445-457 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 445-457
-
-
Friedl, P.1
Gilmour, D.2
-
62
-
-
58149332179
-
Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization
-
Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Trier, S. M. & Keely, P. J. Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization. Biophys. J. 95, 5374-5384 (2008).
-
(2008)
Biophys. J.
, vol.95
, pp. 5374-5384
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Trier, S.M.4
Keely, P.J.5
-
63
-
-
84857603520
-
Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber
-
5 Dec, doi:10.1039/C1IB00128K
-
Haessler, U., Teo, J. C., Foretay, D., Renaud, P. & Swartz, M. A. Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber. Integr. Biol. 5 Dec. 2011 (doi:10.1039/C1IB00128K).
-
(2011)
Integr. Biol.
-
-
Haessler, U.1
Teo, J.C.2
Foretay, D.3
Renaud, P.4
Swartz, M.A.5
-
64
-
-
79957560416
-
Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression
-
Qazi, H., Shi, Z. D. & Tarbell, J. M. Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression. PLoS ONE 6, e20348 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Qazi, H.1
Shi, Z.D.2
Tarbell, J.M.3
-
65
-
-
70349617856
-
Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3D collagen I via upregulation of MMP-1
-
Shi, Z. D., Ji, X. Y., Qazi, H. & Tarbell, J. M. Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3D collagen I via upregulation of MMP-1. Am. J. Physiol. Heart Circ. Physiol. 297, H1225-H1234 (2009).
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
-
-
Shi, Z.D.1
Ji, X.Y.2
Qazi, H.3
Tarbell, J.M.4
-
66
-
-
77954563614
-
Interactions between lymphocytes and myeloid cells regulate pro-versus anti-tumor immunity
-
Denardo, D., Andreu, P. & Coussens, L. M. Interactions between lymphocytes and myeloid cells regulate pro-versus anti-tumor immunity. Cancer Metast. Rev. 29, 309-316 (2010).
-
(2010)
Cancer Metast. Rev.
, vol.29
, pp. 309-316
-
-
Denardo, D.1
Andreu, P.2
Coussens, L.M.3
-
67
-
-
33748750776
-
The tumor-draining lymph node as an immune-privileged site
-
Munn, D. H. & Mellor, A. L. The tumor-draining lymph node as an immune-privileged site. Immunol. Rev. 213, 146-158 (2006).
-
(2006)
Immunol. Rev.
, vol.213
, pp. 146-158
-
-
Munn, D.H.1
Mellor, A.L.2
-
68
-
-
79957925314
-
+ T cells in metastases from melanoma patients
-
+ T cells in metastases from melanoma patients. J. Clin. Invest. 121, 2350-2360 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2350-2360
-
-
Baitsch, L.1
-
69
-
-
79960393113
-
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
-
Facciabene, A. et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells. Nature 475, 226-230 (2011).
-
(2011)
Nature
, vol.475
, pp. 226-230
-
-
Facciabene, A.1
-
70
-
-
77952231121
-
Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
-
Shields, J. D., Kourtis, I. C., Tomei, A. A., Roberts, J. M. & Swartz, M. A. Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science 328, 749-752 (2010).
-
(2010)
Science
, vol.328
, pp. 749-752
-
-
Shields, J.D.1
Kourtis, I.C.2
Tomei, A.A.3
Roberts, J.M.4
Swartz, M.A.5
-
72
-
-
34250356289
-
Extralymphatic tumors prepare draining lymph nodes to invasion via a T-cell cross-tolerance process
-
Preynat-Seauve, O. et al. Extralymphatic tumors prepare draining lymph nodes to invasion via a T-cell cross-tolerance process. Cancer Res. 67, 5009-5016 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 5009-5016
-
-
Preynat-Seauve, O.1
-
73
-
-
35248847969
-
Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes
-
Gerlini, G. et al. Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes. Clin. Immunol. 125, 184-193 (2007).
-
(2007)
Clin. Immunol.
, vol.125
, pp. 184-193
-
-
Gerlini, G.1
-
74
-
-
67649655988
-
Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer
-
Battaglia, A. et al. Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer. Cancer Immunol. Immunother. 58, 1363-1373 (2009).
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 1363-1373
-
-
Battaglia, A.1
-
75
-
-
39649098678
-
Tumour immunity: Effector response to tumour and role of the microenvironment
-
Mantovani, A., Romero, P., Palucka, A. & Marincola, F. Tumour immunity: effector response to tumour and role of the microenvironment. Lancet 371, 771-783 (2008).
-
(2008)
Lancet
, vol.371
, pp. 771-783
-
-
Mantovani, A.1
Romero, P.2
Palucka, A.3
Marincola, F.4
-
76
-
-
77549083441
-
Transforming growth factor β (TGF-β) and inflammation in cancer
-
Bierie, B. & Moses, H. L. Transforming growth factor β (TGF-β) and inflammation in cancer. Cytokine Growth Factor Rev. 21, 49-59 (2010).
-
(2010)
Cytokine Growth Factor Rev.
, vol.21
, pp. 49-59
-
-
Bierie, B.1
Moses, H.L.2
-
77
-
-
77954951446
-
The polarization of immune cells in the tumour environment by TGFβ
-
Flavell, R. A., Sanjabi, S., Wrzesinski, S. H. & Licona-Limon, P. The polarization of immune cells in the tumour environment by TGFβ. Nature Rev. Immunol. 10, 554-567 (2010).
-
(2010)
Nature Rev. Immunol.
, vol.10
, pp. 554-567
-
-
Flavell, R.A.1
Sanjabi, S.2
Wrzesinski, S.H.3
Licona-Limon, P.4
-
78
-
-
58149236744
-
Roles of TGFβ in metastasis
-
Padua, D. & Massague, J. Roles of TGFβ in metastasis. Cell Res. 19, 89-102 (2009).
-
(2009)
Cell Res.
, vol.19
, pp. 89-102
-
-
Padua, D.1
Massague, J.2
-
79
-
-
48549086258
-
Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor β
-
Wei, S. A. et al. Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor β. Cancer Res. 68, 5432-5438 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 5432-5438
-
-
Wei, S.A.1
-
80
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D. I. & Nagaraj, S. Myeloid-derived suppressor cells as regulators of the immune system. Nature Rev. Immunol. 9, 162-174 (2009).
-
(2009)
Nature Rev. Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
81
-
-
37349100945
-
+ myeloid cells that promote metastasis
-
+ myeloid cells that promote metastasis. Cancer Cell 13, 23-35 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 23-35
-
-
Yang, L.1
-
82
-
-
25844504654
-
+ regulatory T cell proliferation
-
+ regulatory T cell proliferation. J. Exp. Med. 202, 919-929 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 919-929
-
-
Ghiringhelli, F.1
-
83
-
-
79952193038
-
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
-
Tan, W. et al. Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature 470, 548-553 (2011).
-
(2011)
Nature
, vol.470
, pp. 548-553
-
-
Tan, W.1
-
84
-
-
42649086026
-
CCR7 and its ligands: Balancing immunity and tolerance
-
Forster, R., Davalos-Misslitz, A. C. & Rot, A. CCR7 and its ligands: balancing immunity and tolerance. Nature Rev. Immunol. 8, 362-371 (2008).
-
(2008)
Nature Rev. Immunol.
, vol.8
, pp. 362-371
-
-
Forster, R.1
Davalos-Misslitz, A.C.2
Rot, A.3
-
85
-
-
77950899035
-
Transmural flow modulates cell and fluid transport functions of lymphatic endothelium
-
Miteva, D. O. et al. Transmural flow modulates cell and fluid transport functions of lymphatic endothelium. Circ. Res. 106, 920-931 (2010).
-
(2010)
Circ. Res.
, vol.106
, pp. 920-931
-
-
Miteva, D.O.1
-
86
-
-
70449713917
-
Fluid flow regulates stromal cell organization and CCL21 expression in a tissueengineered lymph node microenvironment
-
Tomei, A. A., Siegert, S., Britschgi, M. R., Luther, S. A. & Swartz, M. A. Fluid flow regulates stromal cell organization and CCL21 expression in a tissueengineered lymph node microenvironment. J. Immunol. 183, 4273-4283 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 4273-4283
-
-
Tomei, A.A.1
Siegert, S.2
Britschgi, M.R.3
Luther, S.A.4
Swartz, M.A.5
-
87
-
-
58249124355
-
Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype
-
Issa, A., Le, T. X., Shoushtari, A. N., Shields, J. D. & Swartz, M. A. Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype. Cancer Res. 69, 349-357 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 349-357
-
-
Issa, A.1
Le, T.X.2
Shoushtari, A.N.3
Shields, J.D.4
Swartz, M.A.5
-
88
-
-
78751700548
-
Microglia/macrophages promote glioma progression
-
Zhai, H. Y., Heppner, F. L. & Tsirka, S. E. Microglia/macrophages promote glioma progression. Glia 59, 472-485 (2011).
-
(2011)
Glia
, vol.59
, pp. 472-485
-
-
Zhai, H.Y.1
Heppner, F.L.2
Tsirka, S.E.3
-
89
-
-
54849416983
-
Expression and function of T cell homing molecules in Hodgkin's lymphoma
-
Machado, L. et al. Expression and function of T cell homing molecules in Hodgkin's lymphoma. Cancer Immunol. Immunother. 58, 85-94 (2009).
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 85-94
-
-
Machado, L.1
-
90
-
-
55749085491
-
The role of podoplanin in tumor progression and metastasis
-
Raica, M., Cimpean, A. M. & Ribatti, D. The role of podoplanin in tumor progression and metastasis. Anticancer Res. 28, 2997-3006 (2008).
-
(2008)
Anticancer Res.
, vol.28
, pp. 2997-3006
-
-
Raica, M.1
Cimpean, A.M.2
Ribatti, D.3
-
91
-
-
77958616353
-
Podoplanin expression in cancerous stroma induces lymphangiogenesis and predicts lymphatic spread and patient survival
-
Kitano, H. et al. Podoplanin expression in cancerous stroma induces lymphangiogenesis and predicts lymphatic spread and patient survival. Arch. Pathol. Lab. Med. 134, 1520-1527 (2010).
-
(2010)
Arch. Pathol. Lab. Med.
, vol.134
, pp. 1520-1527
-
-
Kitano, H.1
-
92
-
-
77957284078
-
Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin
-
Cueni, L. N. et al. Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin. Am. J. Pathol. 177, 1004-1016 (2010).
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 1004-1016
-
-
Cueni, L.N.1
-
93
-
-
47249155697
-
Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma
-
Kawase, A. et al. Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma. Int. J. Cancer 123, 1053-1059 (2008).
-
(2008)
Int. J. Cancer
, vol.123
, pp. 1053-1059
-
-
Kawase, A.1
-
94
-
-
66949131422
-
Inflammation recapitulates the ontogeny of lymphoid stromal cells
-
Peduto, L. et al. Inflammation recapitulates the ontogeny of lymphoid stromal cells. J. Immunol. 182, 5789-5799 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 5789-5799
-
-
Peduto, L.1
-
95
-
-
49649110969
-
Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses
-
Ahrendt, M., Hammerschmidt, S. I., Pabst, O., Pabst, R. & Bode, U. Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses. J. Immunol. 181, 1898-1907 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 1898-1907
-
-
Ahrendt, M.1
Hammerschmidt, S.I.2
Pabst, O.3
Pabst, R.4
Bode, U.5
-
97
-
-
33846194007
-
Chemokines CCL19 and CCL21 promote activation-induced cell death of antigenresponding T cells
-
Yasuda, T. et al. Chemokines CCL19 and CCL21 promote activation-induced cell death of antigenresponding T cells. Blood 109, 449-456 (2007).
-
(2007)
Blood
, vol.109
, pp. 449-456
-
-
Yasuda, T.1
-
98
-
-
34147184187
-
Generalized multi-organ autoimmunity in CCR7-deficient mice
-
Davalos-Misslitz, A. C. et al. Generalized multi-organ autoimmunity in CCR7-deficient mice. Eur. J. Immunol. 37, 613-622 (2007).
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 613-622
-
-
Davalos-Misslitz, A.C.1
-
99
-
-
33846857321
-
VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
-
Hirakawa, S. et al. VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites. Blood 109, 1010-1017 (2007).
-
(2007)
Blood
, vol.109
, pp. 1010-1017
-
-
Hirakawa, S.1
-
100
-
-
79955957828
-
An important role of lymphatic vessel activation in limiting acute inflammation
-
Huggenberger, R. et al. An important role of lymphatic vessel activation in limiting acute inflammation. Blood 117, 4667-4678 (2011).
-
(2011)
Blood
, vol.117
, pp. 4667-4678
-
-
Huggenberger, R.1
-
101
-
-
79958817911
-
Role of the lymphatic system in the pathogenesis of Crohn's disease
-
Von der Weid, P. Y., Rehal, S. & Ferraz, J. G. P. Role of the lymphatic system in the pathogenesis of Crohn's disease. Curr. Opin. Gastroenterol. 27, 335-341 (2011).
-
(2011)
Curr. Opin. Gastroenterol.
, vol.27
, pp. 335-341
-
-
Von Der Weid, P.Y.1
Rehal, S.2
Ferraz, J.G.P.3
-
102
-
-
79959657080
-
Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival
-
Yin, N. et al. Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival. Transplantation 92, 25-30 (2011).
-
(2011)
Transplantation
, vol.92
, pp. 25-30
-
-
Yin, N.1
-
103
-
-
10744229023
-
Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates
-
Kerjaschki, D. et al. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. J. Am. Soc. Nephrol. 15, 603-612 (2004).
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 603-612
-
-
Kerjaschki, D.1
-
104
-
-
73649130264
-
Crucial role of corneal lymphangiogenesis for allograft rejection in alkali-burned cornea bed
-
Ling, S., Qi, C., Li, W., Xu, J. & Kuang, W. Crucial role of corneal lymphangiogenesis for allograft rejection in alkali-burned cornea bed. Clin. Exp. Ophthalmol. 37, 874-883 (2009).
-
(2009)
Clin. Exp. Ophthalmol.
, vol.37
, pp. 874-883
-
-
Ling, S.1
Qi, C.2
Li, W.3
Xu, J.4
Kuang, W.5
-
105
-
-
33846203293
-
Lymphatic neoangiogenesis in human renal allografts: Results from sequential protocol biopsies
-
Stuht, S. et al. Lymphatic neoangiogenesis in human renal allografts: results from sequential protocol biopsies. Am. J. Transplant. 7, 377-384 (2007).
-
(2007)
Am. J. Transplant.
, vol.7
, pp. 377-384
-
-
Stuht, S.1
-
106
-
-
32244443955
-
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization
-
Angeli, V. et al. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity 24, 203-215 (2006).
-
(2006)
Immunity
, vol.24
, pp. 203-215
-
-
Angeli, V.1
-
107
-
-
77954491955
-
B cell-derived vascular endothelial growth factor α promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes
-
Shrestha, B. et al. B cell-derived vascular endothelial growth factor α promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes. J. Immunol. 184, 4819-4826 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 4819-4826
-
-
Shrestha, B.1
-
108
-
-
78751688024
-
T lymphocytes negatively regulate lymph node lymphatic vessel formation
-
Kataru, R. P. et al. T lymphocytes negatively regulate lymph node lymphatic vessel formation. Immunity 34, 96-107 (2011).
-
(2011)
Immunity
, vol.34
, pp. 96-107
-
-
Kataru, R.P.1
-
109
-
-
33947539744
-
The contribution of B cells to renal interstitial inflammation
-
Heller, F. et al. The contribution of B cells to renal interstitial inflammation. Am. J. Pathol. 170, 457-468 (2007).
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 457-468
-
-
Heller, F.1
-
110
-
-
33748622563
-
Recruitment and activation of naive T cells in the islets by lymphotoxin β receptor-dependent tertiary lymphoid structure
-
Lee, Y. et al. Recruitment and activation of naive T cells in the islets by lymphotoxin β receptor-dependent tertiary lymphoid structure. Immunity 25, 499-509 (2006).
-
(2006)
Immunity
, vol.25
, pp. 499-509
-
-
Lee, Y.1
-
111
-
-
33748461637
-
Is defective lymphatic drainage a trigger for lymphoid neogenesis?
-
Thaunat, O., Kerjaschki, D. & Nicoletti, A. Is defective lymphatic drainage a trigger for lymphoid neogenesis? Trends Immunol. 27, 441-445 (2006).
-
(2006)
Trends Immunol.
, vol.27
, pp. 441-445
-
-
Thaunat, O.1
Kerjaschki, D.2
Nicoletti, A.3
-
112
-
-
68149124237
-
Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism
-
Podgrabinska, S. et al. Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J. Immunol. 183, 1767-1779 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 1767-1779
-
-
Podgrabinska, S.1
-
113
-
-
77951069509
-
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aireindependent direct antigen presentation
-
Cohen, J. N. et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aireindependent direct antigen presentation. J. Exp. Med. 207, 681-688 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 681-688
-
-
Cohen, J.N.1
-
114
-
-
12444297666
-
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
-
Sixt, M. et al. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 22, 19-29 (2005).
-
(2005)
Immunity
, vol.22
, pp. 19-29
-
-
Sixt, M.1
-
115
-
-
35948935059
-
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells
-
Junt, T. et al. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 450, 110-114 (2007).
-
(2007)
Nature
, vol.450
, pp. 110-114
-
-
Junt, T.1
-
116
-
-
78650729152
-
An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma
-
Clement, C. C. et al. An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma. PLoS ONE 5, e9863 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Clement, C.C.1
-
117
-
-
58149097584
-
The who, how and where of antigen presentation to B cells
-
Batista, F. D. & Harwood, N. E. The who, how and where of antigen presentation to B cells. Nature Rev. Immunol. 9, 15-27 (2009).
-
(2009)
Nature Rev. Immunol.
, vol.9
, pp. 15-27
-
-
Batista, F.D.1
Harwood, N.E.2
-
118
-
-
0042696999
-
Antigen presentation to naive CD4 T cells in the lymph node
-
Itano, A. A. & Jenkins, M. K. Antigen presentation to naive CD4 T cells in the lymph node. Nature Immunol. 4, 733-739 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 733-739
-
-
Itano, A.A.1
Jenkins, M.K.2
-
119
-
-
0037152162
-
Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
-
Scheinecker, C., Mchugh, R., Shevach, E. M. & Germain, R. N. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 196, 1079-1090 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1079-1090
-
-
Scheinecker, C.1
Mchugh, R.2
Shevach, E.M.3
Germain, R.N.4
-
120
-
-
0015518318
-
Immunologic Tolerance: Role of the regional lymph node
-
Friedlaender, M. H., Baer, H. Immunologic Tolerance: role of the regional lymph node. Science 176, 312-314 (1972).
-
(1972)
Science
, vol.176
, pp. 312-314
-
-
Friedlaender, M.H.1
Baer, H.2
-
121
-
-
34248173331
-
Indoleamine 2, 3-dioxygenase and tumor-induced tolerance
-
Munn, D. & Mellor, A. Indoleamine 2, 3-dioxygenase and tumor-induced tolerance. J. Clin. Invest. 117, 1147-1154 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1147-1154
-
-
Munn, D.1
Mellor, A.2
-
122
-
-
79957879331
-
Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis
-
Hood, J. L., San, R. S. & Wickline, S. A. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. Cancer Res. 71, 3792-3801 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 3792-3801
-
-
Hood, J.L.1
San, R.S.2
Wickline, S.A.3
-
123
-
-
79952070774
-
The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
-
Peinado, H., Lavotshkin, S. & Lyden, D. The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts. Semin. Cancer Biol. 21, 139-146 (2011).
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 139-146
-
-
Peinado, H.1
Lavotshkin, S.2
Lyden, D.3
-
124
-
-
77957571628
-
Differential cytokine responses in human and mouse lymphatic endothelial cells to cytokines in vitro
-
Chaitanya, G. V. et al. Differential cytokine responses in human and mouse lymphatic endothelial cells to cytokines in vitro. Lymphat. Res. Biol. 8, 155-164 (2010).
-
(2010)
Lymphat. Res. Biol.
, vol.8
, pp. 155-164
-
-
Chaitanya, G.V.1
-
125
-
-
81755186998
-
Impaired lymphatic contraction associated with immunosuppression
-
Liao, S. et al. Impaired lymphatic contraction associated with immunosuppression. Proc. Natl Acad. Sci. USA 108, 18784-18789 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 18784-18789
-
-
Liao, S.1
-
126
-
-
78650738468
-
Lymph node stroma broaden the peripheral tolerance paradigm
-
Fletcher, A. L., Malhotra, D. & Turley, S. J. Lymph node stroma broaden the peripheral tolerance paradigm. Trends Immunol. 32, 12-18 (2011).
-
(2011)
Trends Immunol.
, vol.32
, pp. 12-18
-
-
Fletcher, A.L.1
Malhotra, D.2
Turley, S.J.3
-
127
-
-
77951074210
-
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
-
Fletcher, A. L. et al. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J. Exp. Med. 207, 689-697 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 689-697
-
-
Fletcher, A.L.1
-
128
-
-
84861116064
-
VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics
-
23 Feb, doi:10.1016/j.celrep. 2012.01.005
-
Lund, A. W. et al. VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics. Cell Rep. 23 Feb. 2012 (doi:10.1016/j.celrep. 2012.01.005).
-
(2012)
Cell Rep.
-
-
Lund, A.W.1
-
129
-
-
0037405904
-
Fibroblast alignment under interstitial fluid flow using a novel 3D tissue culture model
-
Ng, C. P. & Swartz, M. A. Fibroblast alignment under interstitial fluid flow using a novel 3D tissue culture model. Am. J. Physiol. Heart Circ. Physiol. 284, H1771-H1777 (2003).
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.284
-
-
Ng, C.P.1
Swartz, M.A.2
-
130
-
-
57049131450
-
The conduit system of the lymph node
-
Roozendaal, R., Mebius, R. E. & Kraal, G. The conduit system of the lymph node. Int. Immunol. 20, 1483-1487 (2008).
-
(2008)
Int. Immunol.
, vol.20
, pp. 1483-1487
-
-
Roozendaal, R.1
Mebius, R.E.2
Kraal, G.3
-
131
-
-
0026014880
-
The influence of afferent lymphatic vessel interruption on vascular addressin expression
-
Mebius, R. E., Streeter, P. R., Breve, J., Duijvestijn, A. M. & Kraal, G. The influence of afferent lymphatic vessel interruption on vascular addressin expression. J. Cell Biol. 115, 85-95 (1991).
-
(1991)
J. Cell Biol.
, vol.115
, pp. 85-95
-
-
Mebius, R.E.1
Streeter, P.R.2
Breve, J.3
Duijvestijn, A.M.4
Kraal, G.5
|