메뉴 건너뛰기




Volumn 28, Issue 3, 2014, Pages 571-583

Interferon, Interleukin-2, and Other Cytokines

Author keywords

Cytokines; Granulocyte macrophage colony stimulating factor; Interferon; Interleukin 2; Interleukin 21; Melanoma

Indexed keywords

ALPHA INTERFERON; ALPHA2B INTERFERON; CISPLATIN; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; DACARBAZINE; GLYCOPROTEIN GP 100; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERFERON; INTERLEUKIN 2; INTERLEUKIN 21; IPILIMUMAB; MELANOMA VACCINE; PEGINTERFERON ALPHA2B; PEPTIDE VACCINE; PHOSPHOLIPID ANTIBODY; PLACEBO; VINBLASTINE;

EID: 84901618784     PISSN: 08898588     EISSN: 15581977     Source Type: Journal    
DOI: 10.1016/j.hoc.2014.02.001     Document Type: Review
Times cited : (18)

References (53)
  • 2
    • 34249751575 scopus 로고    scopus 로고
    • Another road to interferon: Yasuichi Nagano's journey
    • Ozato K., Uno K., Iwakura Y. Another road to interferon: Yasuichi Nagano's journey. JInterferon Cytokine Res 2007, 27:349-352.
    • (2007) JInterferon Cytokine Res , vol.27 , pp. 349-352
    • Ozato, K.1    Uno, K.2    Iwakura, Y.3
  • 3
    • 9644262469 scopus 로고    scopus 로고
    • Interferons, interferon-like cytokines, and their receptors
    • Pestka S., Krause C.D., Walter M.R. Interferons, interferon-like cytokines, and their receptors. Immunol Rev 2004, 202:8-32.
    • (2004) Immunol Rev , vol.202 , pp. 8-32
    • Pestka, S.1    Krause, C.D.2    Walter, M.R.3
  • 4
    • 34547099363 scopus 로고    scopus 로고
    • The interferons: 50 years after their discovery, there is much more to learn
    • Pestka S. The interferons: 50 years after their discovery, there is much more to learn. JBiol Chem 2007, 282:20047-20051.
    • (2007) JBiol Chem , vol.282 , pp. 20047-20051
    • Pestka, S.1
  • 5
    • 0018865994 scopus 로고
    • Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence
    • Knight E., Hunkapiller M.W., Korant B.D., et al. Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence. Science 1980, 207:525-526.
    • (1980) Science , vol.207 , pp. 525-526
    • Knight, E.1    Hunkapiller, M.W.2    Korant, B.D.3
  • 6
    • 0019128380 scopus 로고
    • Two interferon mRNAs in human fibroblasts: invitro translation and Escherichia coli cloning studies
    • Weissenbach J., Chernajovsky Y., Zeevi M., et al. Two interferon mRNAs in human fibroblasts: invitro translation and Escherichia coli cloning studies. Proc Natl Acad Sci USA 1980, 77:7152-7156.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 7152-7156
    • Weissenbach, J.1    Chernajovsky, Y.2    Zeevi, M.3
  • 7
    • 34548129596 scopus 로고    scopus 로고
    • Historical developments in the research of interferon receptors
    • Krause C.D., Pestka S. Historical developments in the research of interferon receptors. Cytokine Growth Factor Rev 2007, 18:473-482.
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 473-482
    • Krause, C.D.1    Pestka, S.2
  • 8
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell J.E., Kerr I.M., Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 9
    • 0036720445 scopus 로고    scopus 로고
    • Immunomodulatory effects of high-dose and low-dose interferon a2b in patients with high-risk resected melanoma: the E2690 laboratory corollary of intergroup adjuvant trial E1690
    • Kirkwood J.M., Richards T., Zarour H.M., et al. Immunomodulatory effects of high-dose and low-dose interferon a2b in patients with high-risk resected melanoma: the E2690 laboratory corollary of intergroup adjuvant trial E1690. Cancer 2002, 95:1101-1112.
    • (2002) Cancer , vol.95 , pp. 1101-1112
    • Kirkwood, J.M.1    Richards, T.2    Zarour, H.M.3
  • 10
  • 11
    • 0021258148 scopus 로고
    • Human leukocyte (alpha) interferon in metastatic malignant melanoma: the American Cancer Society phase II trial
    • Krown S.E., Burk M.W., Kirkwood J.M., et al. Human leukocyte (alpha) interferon in metastatic malignant melanoma: the American Cancer Society phase II trial. Cancer Treat Rep 1984, 68:723-726.
    • (1984) Cancer Treat Rep , vol.68 , pp. 723-726
    • Krown, S.E.1    Burk, M.W.2    Kirkwood, J.M.3
  • 12
    • 0021246077 scopus 로고
    • Interferons in the treatment of human cancer
    • Kirkwood J.M., Ernstoff M.S. Interferons in the treatment of human cancer. JClin Oncol 1984, 2:336-351.
    • (1984) JClin Oncol , vol.2 , pp. 336-351
    • Kirkwood, J.M.1    Ernstoff, M.S.2
  • 13
    • 0020683755 scopus 로고
    • Evaluation of human lyphoblastoid interferon in advanced malignant melanoma
    • Retsas S., Priestman T.J., Newton K.A., et al. Evaluation of human lyphoblastoid interferon in advanced malignant melanoma. Cancer 1982, 51:273-276.
    • (1982) Cancer , vol.51 , pp. 273-276
    • Retsas, S.1    Priestman, T.J.2    Newton, K.A.3
  • 14
    • 0022859297 scopus 로고
    • Recombinant leukocyte A interferon (rIFN-aA) in the treatment of disseminated malignant melanoma. Analysis of complete and long-term responding patients
    • Creagan E.T., Ahmann D.L., Frytak S., et al. Recombinant leukocyte A interferon (rIFN-aA) in the treatment of disseminated malignant melanoma. Analysis of complete and long-term responding patients. Cancer 1986, 58:2576-2578.
    • (1986) Cancer , vol.58 , pp. 2576-2578
    • Creagan, E.T.1    Ahmann, D.L.2    Frytak, S.3
  • 15
    • 0030030347 scopus 로고    scopus 로고
    • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684
    • Kirkwood J.M., Strawderman M.H., Ernstoff M.S., et al. Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. JClin Oncol 1996, 14:7-17.
    • (1996) JClin Oncol , vol.14 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3
  • 16
    • 0034088027 scopus 로고    scopus 로고
    • High- and low-dose interferon alfa-2b in high risk melanoma: first analysis of intergroup trial E1690/S9111/C9190
    • Kirkwood J.M., Ibrahim J.G., Sondak V.K., et al. High- and low-dose interferon alfa-2b in high risk melanoma: first analysis of intergroup trial E1690/S9111/C9190. JClin Oncol 2000, 18:2444-2458.
    • (2000) JClin Oncol , vol.18 , pp. 2444-2458
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sondak, V.K.3
  • 17
    • 0028205790 scopus 로고
    • Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside
    • Livingston P.O., Wong G.Y.C., Adluri S., et al. Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside. JClin Oncol 1994, 12:1036-1044.
    • (1994) JClin Oncol , vol.12 , pp. 1036-1044
    • Livingston, P.O.1    Wong, G.Y.C.2    Adluri, S.3
  • 18
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801
    • Kirkwood J.M., Ibrahim J.G., Sosman J.A., et al. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. JClin Oncol 2001, 19:2370-2380.
    • (2001) JClin Oncol , vol.19 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3
  • 19
    • 0041409703 scopus 로고    scopus 로고
    • Does adjuvant interferon-α for high-risk melanoma provide a worthwhile benefit? A meta-analysis of randomized trials
    • Wheatley K., Ives N., Hancock B., et al. Does adjuvant interferon-α for high-risk melanoma provide a worthwhile benefit? A meta-analysis of randomized trials. Cancer Treat Rev 2003, 29:241-252.
    • (2003) Cancer Treat Rev , vol.29 , pp. 241-252
    • Wheatley, K.1    Ives, N.2    Hancock, B.3
  • 20
    • 35649015750 scopus 로고    scopus 로고
    • Interferon-α as adjuvant therapy for melanoma: an individual patient data meta-analysis of randomized trials
    • [abstract] International Malignant Melanoma Collaborative Group
    • Wheatley K., Ives N., Eggermont A., International Malignant Melanoma Collaborative Group, et al. Interferon-α as adjuvant therapy for melanoma: an individual patient data meta-analysis of randomized trials. JClin Oncol 2007, 25:8526. [abstract].
    • (2007) JClin Oncol , vol.25 , pp. 8526
    • Wheatley, K.1    Ives, N.2    Eggermont, A.3
  • 21
    • 77950576363 scopus 로고    scopus 로고
    • Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis
    • Mocellin S., Pasquali S., Rossi C.F., et al. Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis. JNatl Cancer Inst 2010, 102:493-501.
    • (2010) JNatl Cancer Inst , vol.102 , pp. 493-501
    • Mocellin, S.1    Pasquali, S.2    Rossi, C.F.3
  • 22
    • 46749103710 scopus 로고    scopus 로고
    • Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomized phase III trial
    • Eggermont A.M., Suciu S., Santinami M., et al. Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomized phase III trial. Lancet 2008, 372:117-126.
    • (2008) Lancet , vol.372 , pp. 117-126
    • Eggermont, A.M.1    Suciu, S.2    Santinami, M.3
  • 23
    • 84655168007 scopus 로고    scopus 로고
    • Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991
    • Eggermont A.M., Suciu S., Tesori A., et al. Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991. Eur J Cancer 2012, 48:218-225.
    • (2012) Eur J Cancer , vol.48 , pp. 218-225
    • Eggermont, A.M.1    Suciu, S.2    Tesori, A.3
  • 24
    • 60849108348 scopus 로고    scopus 로고
    • Randomized phase III study of 1 month versus 1 year of adjuvant high-dose interferon alfa-2b in patients with resected high-risk melanoma
    • Pectasides D., Dafni U., Bafaloukos D., et al. Randomized phase III study of 1 month versus 1 year of adjuvant high-dose interferon alfa-2b in patients with resected high-risk melanoma. JClin Oncol 2009, 27:939-944.
    • (2009) JClin Oncol , vol.27 , pp. 939-944
    • Pectasides, D.1    Dafni, U.2    Bafaloukos, D.3
  • 25
    • 84859386046 scopus 로고    scopus 로고
    • Randomized phase III trial of high-dose interferon alfa-2b (HDI) for 4 weeks induction only in patients with intermediate- and high-risk melanoma (Intergroup trial E1697)
    • [abstract 8505]
    • Agarwala S.S., Lee S.J., Flaherty L.E., et al. Randomized phase III trial of high-dose interferon alfa-2b (HDI) for 4 weeks induction only in patients with intermediate- and high-risk melanoma (Intergroup trial E1697). JClin Oncol 2011, 29(Suppl). [abstract 8505].
    • (2011) JClin Oncol , vol.29 , Issue.SUPPL
    • Agarwala, S.S.1    Lee, S.J.2    Flaherty, L.E.3
  • 26
    • 32644454916 scopus 로고    scopus 로고
    • Prognostic significance of autoimmunity during treatment of melanoma with interferon
    • Gogas H., Ioannovich J., Dafni U., et al. Prognostic significance of autoimmunity during treatment of melanoma with interferon. NEngl J Med 2006, 16:709-718.
    • (2006) NEngl J Med , vol.16 , pp. 709-718
    • Gogas, H.1    Ioannovich, J.2    Dafni, U.3
  • 27
    • 0017199306 scopus 로고
    • Selective invitro growth of T lymphocytes for normal human bone marrows
    • Morgan D.A., Ruscetti F.W., Gallo R. Selective invitro growth of T lymphocytes for normal human bone marrows. Science 1976, 193:1007-1008.
    • (1976) Science , vol.193 , pp. 1007-1008
    • Morgan, D.A.1    Ruscetti, F.W.2    Gallo, R.3
  • 28
    • 0020699991 scopus 로고
    • Structure and expression of cloned cDNA for human interleukin-2
    • Taniguchi T., Matsui H., Fujita T., et al. Structure and expression of cloned cDNA for human interleukin-2. Nature 1983, 302:305-310.
    • (1983) Nature , vol.302 , pp. 305-310
    • Taniguchi, T.1    Matsui, H.2    Fujita, T.3
  • 29
    • 0023145014 scopus 로고
    • Interleukin-2 receptors: biology and therapeutic potentials
    • 93-4
    • Waldmann T.A., Tsudo M. Interleukin-2 receptors: biology and therapeutic potentials. Hosp Pract (Off Ed) 1987, 22:77-84. 93-4.
    • (1987) Hosp Pract (Off Ed) , vol.22 , pp. 77-84
    • Waldmann, T.A.1    Tsudo, M.2
  • 30
    • 0027096349 scopus 로고
    • IL2 treatment for cancer: from biology to gene therapy
    • Foa R., Guarini A., Gansbacher B. IL2 treatment for cancer: from biology to gene therapy. Br J Cancer 1992, 66:992-998.
    • (1992) Br J Cancer , vol.66 , pp. 992-998
    • Foa, R.1    Guarini, A.2    Gansbacher, B.3
  • 31
    • 0021837706 scopus 로고
    • Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2
    • Rosenberg S.A., Mule J.J., Speiss P.J., et al. Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2. JExp Med 1985, 161:1169-1188.
    • (1985) JExp Med , vol.161 , pp. 1169-1188
    • Rosenberg, S.A.1    Mule, J.J.2    Speiss, P.J.3
  • 32
    • 0022349817 scopus 로고
    • Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer
    • Rosenberg S.A., Lotze M.T., Muul L.M., et al. Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer. NEngl J Med 1985, 313:1485-1492.
    • (1985) NEngl J Med , vol.313 , pp. 1485-1492
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3
  • 33
    • 0023115642 scopus 로고
    • Aprogress report on the treatment of 157 patients with advanced cancer using lymphokine activated killer cells and interleukin-2 or high-dose interleukin-2 alone
    • Rosenberg S.A., Lotze M.T., Muul L.M., et al. Aprogress report on the treatment of 157 patients with advanced cancer using lymphokine activated killer cells and interleukin-2 or high-dose interleukin-2 alone. NEngl J Med 1987, 316:889-897.
    • (1987) NEngl J Med , vol.316 , pp. 889-897
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3
  • 34
    • 0027529476 scopus 로고
    • Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells of the treatment of patients with advanced cancer
    • Rosenberg S.A., Lotze M.T., Yang J.C., et al. Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells of the treatment of patients with advanced cancer. JNatl Cancer Inst 1993, 85:622-632.
    • (1993) JNatl Cancer Inst , vol.85 , pp. 622-632
    • Rosenberg, S.A.1    Lotze, M.T.2    Yang, J.C.3
  • 35
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
    • Atkins M.B., Lotze M.T., Dutcher J.P., et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. JClin Oncol 1999, 17:2105-2116.
    • (1999) JClin Oncol , vol.17 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3
  • 36
    • 0033848628 scopus 로고    scopus 로고
    • High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update
    • Atkins M.B., Kunkel L., Sznol M., et al. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am 2006, 6(Suppl 1):11-14.
    • (2006) Cancer J Sci Am , vol.6 , Issue.SUPPL 1 , pp. 11-14
    • Atkins, M.B.1    Kunkel, L.2    Sznol, M.3
  • 37
    • 53949108399 scopus 로고    scopus 로고
    • Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group
    • Atkins M.B., Hsu J., Lee S., et al. Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group. JClin Oncol 2008, 10:5748-5754.
    • (2008) JClin Oncol , vol.10 , pp. 5748-5754
    • Atkins, M.B.1    Hsu, J.2    Lee, S.3
  • 38
    • 74949089360 scopus 로고    scopus 로고
    • Phase II multicenter trial of maintenance biotherapy after induction concurrent biochemotherapy for patients with metastatic melanoma
    • O'Day S.J., Atkins M.B., Baosberg P., et al. Phase II multicenter trial of maintenance biotherapy after induction concurrent biochemotherapy for patients with metastatic melanoma. J Clin Oncol 2009, 27:6207-6212.
    • (2009) J Clin Oncol , vol.27 , pp. 6207-6212
    • O'Day, S.J.1    Atkins, M.B.2    Baosberg, P.3
  • 39
    • 33646252963 scopus 로고    scopus 로고
    • Cytokine-based therapy and biochemotherapy for advanced melanoma
    • Atkins M.B. Cytokine-based therapy and biochemotherapy for advanced melanoma. Clin Cancer Res 2006, 12:2353s-2358s.
    • (2006) Clin Cancer Res , vol.12
    • Atkins, M.B.1
  • 40
    • 79957831345 scopus 로고    scopus 로고
    • Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
    • Schwarzentruber D.J., Lawson D.H., Richards J.M., et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. NEngl J Med 2011, 364:2119-2127.
    • (2011) NEngl J Med , vol.364 , pp. 2119-2127
    • Schwarzentruber, D.J.1    Lawson, D.H.2    Richards, J.M.3
  • 41
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley M.E., Jang J.C., Sherry R., et al. Adoptive cell therapy for patients with metastic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. JClin Oncol 2008, 26:5233-5239.
    • (2008) JClin Oncol , vol.26 , pp. 5233-5239
    • Dudley, M.E.1    Jang, J.C.2    Sherry, R.3
  • 42
    • 0002013401 scopus 로고
    • The clinical toxicities of high-dose interleukin-2
    • Marcel Dekker Inc, New York, M. Atkins (Ed.)
    • Margolin K. The clinical toxicities of high-dose interleukin-2. Therapeutic applications of interleukin-2 1993, 331-362. Marcel Dekker Inc, New York. M. Atkins (Ed.).
    • (1993) Therapeutic applications of interleukin-2 , pp. 331-362
    • Margolin, K.1
  • 43
    • 0031812910 scopus 로고    scopus 로고
    • Trends in the safety of high dose bolus interleukin-2 administration in patients with metastatic cancer
    • Kammula U.S., White D.E., Rosenberg S.A., et al. Trends in the safety of high dose bolus interleukin-2 administration in patients with metastatic cancer. Cancer 1998, 83:797-805.
    • (1998) Cancer , vol.83 , pp. 797-805
    • Kammula, U.S.1    White, D.E.2    Rosenberg, S.A.3
  • 44
    • 0035425425 scopus 로고    scopus 로고
    • Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma
    • Phan G.Q., Attia P., Steinberg S.M., et al. Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma. JClin Oncol 2001, 19:3477-3482.
    • (2001) JClin Oncol , vol.19 , pp. 3477-3482
    • Phan, G.Q.1    Attia, P.2    Steinberg, S.M.3
  • 45
    • 0036645090 scopus 로고    scopus 로고
    • Prospective molecular profiling of melanoma metastasis suggests classifiers of immune responsiveness
    • Wang E., Miller L.D., Ohnmacht G.A., et al. Prospective molecular profiling of melanoma metastasis suggests classifiers of immune responsiveness. Cancer Res 2002, 62:3581-3586.
    • (2002) Cancer Res , vol.62 , pp. 3581-3586
    • Wang, E.1    Miller, L.D.2    Ohnmacht, G.A.3
  • 46
    • 84155171313 scopus 로고    scopus 로고
    • Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma
    • Joseph R.W., Sullivan R.J., Harrell R., et al. Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma. JImmunother 2012, 35:66-72.
    • (2012) JImmunother , vol.35 , pp. 66-72
    • Joseph, R.W.1    Sullivan, R.J.2    Harrell, R.3
  • 47
    • 37249029836 scopus 로고    scopus 로고
    • Interleukin-21 signaling: functions in cancer and autoimmunity
    • Davis I.D., Skak K., Smyth M.J., et al. Interleukin-21 signaling: functions in cancer and autoimmunity. Clin Cancer Res 2007, 13:6926-6932.
    • (2007) Clin Cancer Res , vol.13 , pp. 6926-6932
    • Davis, I.D.1    Skak, K.2    Smyth, M.J.3
  • 48
    • 84866772544 scopus 로고    scopus 로고
    • Interleukin-21 has activity in patients with metastatic melanoma: a phase II study
    • Petrella T.M., Tozer R., Belanger K., et al. Interleukin-21 has activity in patients with metastatic melanoma: a phase II study. JClin Oncol 2012, 30:3396-3401.
    • (2012) JClin Oncol , vol.30 , pp. 3396-3401
    • Petrella, T.M.1    Tozer, R.2    Belanger, K.3
  • 49
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G., Jaffee E., Lazenby A., et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993, 90:3539-3543.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3
  • 50
    • 0029877716 scopus 로고    scopus 로고
    • Antitumor effects of granulocyte-macrophage colony stimulating factor production by melanoma cells
    • Armstrong C.A., Botella R., Galloway T.H., et al. Antitumor effects of granulocyte-macrophage colony stimulating factor production by melanoma cells. Cancer Res 1996, 56:2191-2198.
    • (1996) Cancer Res , vol.56 , pp. 2191-2198
    • Armstrong, C.A.1    Botella, R.2    Galloway, T.H.3
  • 51
    • 84880263903 scopus 로고    scopus 로고
    • Multicenter, randomized phase II trial of GM-CSF (GM) plus ipilimumab (Ipi) versus Ipi alone in metastatic melanoma: E1608
    • [abstract CRA9007]
    • Hodi S.F., Lee S.J., McDermott D.F., et al. Multicenter, randomized phase II trial of GM-CSF (GM) plus ipilimumab (Ipi) versus Ipi alone in metastatic melanoma: E1608. JClin Oncol 2013, 31(Suppl). [abstract CRA9007].
    • (2013) JClin Oncol , vol.31 , Issue.SUPPL
    • Hodi, S.F.1    Lee, S.J.2    McDermott, D.F.3
  • 52
    • 0036016473 scopus 로고    scopus 로고
    • Preliminary experiences of intralesional immunotherapy in cutaneous metastatic melanoma
    • Ridolfi L., Ridolfi R. Preliminary experiences of intralesional immunotherapy in cutaneous metastatic melanoma. Hepatogastroenterology 2002, 49:335-339.
    • (2002) Hepatogastroenterology , vol.49 , pp. 335-339
    • Ridolfi, L.1    Ridolfi, R.2
  • 53
    • 84884594361 scopus 로고    scopus 로고
    • OPTiM: a randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment of unresected stage IIIB/C and IV melanoma
    • [abstract LBA9008]
    • Andtbacka R.H., Collichio F.A., Amatruda T., et al. OPTiM: a randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment of unresected stage IIIB/C and IV melanoma. JClin Oncol 2013, 31(Suppl). [abstract LBA9008].
    • (2013) JClin Oncol , vol.31 , Issue.SUPPL
    • Andtbacka, R.H.1    Collichio, F.A.2    Amatruda, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.