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Volumn 445, Issue 7128, 2007, Pages 656-660

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 33846937033     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05529     Document Type: Article
Times cited : (2018)

References (30)
  • 1
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: Positive and negative feedback loops
    • Harris, S. L. & Levine, A. J. The p53 pathway: positive and negative feedback loops. Oncogene 24, 2899-2908 (2005).
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 2
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr, C. J. Principles of tumor suppression. Cell 116, 235-246 (2004).
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 3
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe, S. W., Cepero, E. & Evan, G. Intrinsic tumour suppression. Nature 432, 307-315 (2004).
    • (2004) Nature , vol.432 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 4
    • 33746441453 scopus 로고    scopus 로고
    • Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors
    • Zender, L. et al. Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors. Cold Spring Harb. Symp. Quant. Biol. 70, 251-261 (2005).
    • (2005) Cold Spring Harb. Symp. Quant. Biol , vol.70 , pp. 251-261
    • Zender, L.1
  • 5
    • 33745253109 scopus 로고    scopus 로고
    • Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
    • Zender, L. et al. Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 125, 1253-1267 (2006).
    • (2006) Cell , vol.125 , pp. 1253-1267
    • Zender, L.1
  • 6
    • 0037222429 scopus 로고    scopus 로고
    • Staib, F., Hussain, S. P., Hofseth, L. J., Wang, X. W. & Harris, C. C. TP53 and liver carcinogenesis. Hum. Mutat. 21, 201-216 (2003).
    • Staib, F., Hussain, S. P., Hofseth, L. J., Wang, X. W. & Harris, C. C. TP53 and liver carcinogenesis. Hum. Mutat. 21, 201-216 (2003).
  • 7
    • 27644582893 scopus 로고    scopus 로고
    • Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
    • Dickins, R. A. et al. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nature Genet. 37, 1289-1295 (2005).
    • (2005) Nature Genet , vol.37 , pp. 1289-1295
    • Dickins, R.A.1
  • 8
    • 27644436787 scopus 로고    scopus 로고
    • Second-generation shRNA libraries covering the mouse and human genomes
    • Silva, J. M. et al. Second-generation shRNA libraries covering the mouse and human genomes. Nature Genet. 37, 1281-1288 (2005).
    • (2005) Nature Genet , vol.37 , pp. 1281-1288
    • Silva, J.M.1
  • 9
    • 0033614962 scopus 로고    scopus 로고
    • Essential role for oncogenic Ras in tumour maintenance
    • Chin, L. et al. Essential role for oncogenic Ras in tumour maintenance. Nature 400, 468-472 (1999).
    • (1999) Nature , vol.400 , pp. 468-472
    • Chin, L.1
  • 10
    • 0037025201 scopus 로고    scopus 로고
    • Sustained loss of a neoplastic phenotype by brief inactivation of MYC
    • Jain, M. et al. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 297, 102-104 (2002).
    • (2002) Science , vol.297 , pp. 102-104
    • Jain, M.1
  • 11
    • 23244461708 scopus 로고    scopus 로고
    • Oncogene-induced senescence as an initial barrier in lymphoma development
    • Braig, M. et al. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436, 660-665 (2005).
    • (2005) Nature , vol.436 , pp. 660-665
    • Braig, M.1
  • 12
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • Chen, Z. et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436, 725-730 (2005).
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1
  • 13
    • 23244447893 scopus 로고    scopus 로고
    • Tumour biology: Senescence in premalignant tumours
    • Collado, M. et al. Tumour biology: senescence in premalignant tumours. Nature 436, 642 (2005).
    • (2005) Nature , vol.436 , pp. 642
    • Collado, M.1
  • 14
    • 23244447037 scopus 로고    scopus 로고
    • E600-associated senescence-like cell cycle arrest of human naevi
    • E600-associated senescence-like cell cycle arrest of human naevi. Nature 436, 720-724 (2005).
    • (2005) Nature , vol.436 , pp. 720-724
    • Michaloglou, C.1
  • 16
    • 0242361641 scopus 로고    scopus 로고
    • Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis
    • Minamino, T. et al. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 108, 2264-2269 (2003).
    • (2003) Circulation , vol.108 , pp. 2264-2269
    • Minamino, T.1
  • 18
    • 17144400369 scopus 로고    scopus 로고
    • p53-dependent ICAM-1 overexpression in senescent human cells identified in atherosclerotic lesions
    • Gorgoulis, V. G. et al. p53-dependent ICAM-1 overexpression in senescent human cells identified in atherosclerotic lesions. Lab. Invest. 85, 502-511 (2005).
    • (2005) Lab. Invest , vol.85 , pp. 502-511
    • Gorgoulis, V.G.1
  • 19
    • 21244472975 scopus 로고    scopus 로고
    • IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
    • Maeda, S., Kamata, H., Luo, J. L., Leffert, H. & Karin, M. IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121, 977-990 (2005).
    • (2005) Cell , vol.121 , pp. 977-990
    • Maeda, S.1    Kamata, H.2    Luo, J.L.3    Leffert, H.4    Karin, M.5
  • 20
    • 0037268529 scopus 로고    scopus 로고
    • Involvement of TRAIL and its receptors in viral hepatitis
    • Mundt, B. et al. Involvement of TRAIL and its receptors in viral hepatitis. FASEB J. 17, 94-96 (2003).
    • (2003) FASEB J , vol.17 , pp. 94-96
    • Mundt, B.1
  • 21
    • 0346690258 scopus 로고    scopus 로고
    • β-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells
    • Hong, F. et al. β-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells. Cancer Res. 63, 9023-9031 (2003).
    • (2003) Cancer Res , vol.63 , pp. 9023-9031
    • Hong, F.1
  • 22
    • 0028869986 scopus 로고
    • Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice
    • Shultz, L. D. et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J. Immunol. 154, 180-191 (1995).
    • (1995) J. Immunol , vol.154 , pp. 180-191
    • Shultz, L.D.1
  • 23
    • 33750691006 scopus 로고    scopus 로고
    • The role of regulatory T cells in the control of natural killer cells: Relevance during tumor progression
    • Ghiringhelli, F., Menard, C., Martin, F. & Zitvogel, L. The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression. Immunol. Rev. 214, 229-238 (2006).
    • (2006) Immunol. Rev , vol.214 , pp. 229-238
    • Ghiringhelli, F.1    Menard, C.2    Martin, F.3    Zitvogel, L.4
  • 24
    • 33846899456 scopus 로고    scopus 로고
    • Restoration of p53 function leads to tumour regression in vivo
    • publication, doi:10.1038/nature05541 24 January
    • Ventura, A. et al. Restoration of p53 function leads to tumour regression in vivo. Nature advance online publication, doi:10.1038/nature05541 (24 January 2007).
    • (2007) Nature advance online
    • Ventura, A.1
  • 25
    • 33748670457 scopus 로고    scopus 로고
    • The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
    • Christophorou, M. A., Ringshausen, I., Finch, A. J., Swigart, L. B. & Evan, G. I. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature 443, 214-217 (2006).
    • (2006) Nature , vol.443 , pp. 214-217
    • Christophorou, M.A.1    Ringshausen, I.2    Finch, A.J.3    Swigart, L.B.4    Evan, G.I.5
  • 26
    • 0036128899 scopus 로고    scopus 로고
    • Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
    • Bykov, V. J. et al. Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nature Med. 8, 282-288 (2002).
    • (2002) Nature Med , vol.8 , pp. 282-288
    • Bykov, V.J.1
  • 27
    • 10744221485 scopus 로고    scopus 로고
    • In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
    • Vassilev, L. T. et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303, 844-848 (2004).
    • (2004) Science , vol.303 , pp. 844-848
    • Vassilev, L.T.1
  • 28
    • 33747192833 scopus 로고    scopus 로고
    • Cellular senescence in naevi and immortalisation in melanoma: A role for p16?
    • Gray-Schopfer, V. C. et al. Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br. J. Cancer 95, 496-505 (2006).
    • (2006) Br. J. Cancer , vol.95 , pp. 496-505
    • Gray-Schopfer, V.C.1
  • 29
    • 0038277105 scopus 로고    scopus 로고
    • Tumor cell senescence in cancer treatment
    • Roninson, I. B. Tumor cell senescence in cancer treatment. Cancer Res. 63, 2705-2715 (2003).
    • (2003) Cancer Res , vol.63 , pp. 2705-2715
    • Roninson, I.B.1
  • 30
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
    • Krtolica, A., Parrinello, S., Lockett, S., Desprez, P. Y. & Campisi, J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc. Natl Acad. Sci. USA 98, 12072-12077 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.