메뉴 건너뛰기




Volumn 18, Issue 40, 2012, Pages 5688-5694

Regulatory T cells in inflammatory bowel diseases and colorectal cancer

Author keywords

Colitis associated colon cancer; Colorectal cancer; Forkhead box P3; Inflammatory bowel diseases; Regulatory T cells

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; RANTES; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RUNX; TRANSFORMING GROWTH FACTOR BETA;

EID: 84873930620     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v18.i40.5688     Document Type: Review
Times cited : (39)

References (70)
  • 1
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001; 193: 1303-1310
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 2
    • 0035819467 scopus 로고    scopus 로고
    • Prospects for research in inflammatory bowel disease
    • Blumberg RS, Strober W. Prospects for research in inflammatory bowel disease. JAMA 2001; 285: 643-647
    • (2001) JAMA , vol.285 , pp. 643-647
    • Blumberg, R.S.1    Strober, W.2
  • 3
    • 79960705112 scopus 로고    scopus 로고
    • Expression of CD4+ forkhead box P3 (FOXP3)+ regulatory T cells in inflammatory bowel disease
    • Wang Y, Liu XP, Zhao ZB, Chen JH, Yu CG. Expression of CD4+ forkhead box P3 (FOXP3)+ regulatory T cells in inflammatory bowel disease. J Dig Dis 2011; 12: 286-294
    • (2011) J Dig Dis , vol.12 , pp. 286-294
    • Wang, Y.1    Liu, X.P.2    Zhao, Z.B.3    Chen, J.H.4    Yu, C.G.5
  • 4
    • 77952305365 scopus 로고    scopus 로고
    • Roles for inflammation and regulatory T cells in colon cancer
    • Erdman SE, Poutahidis T. Roles for inflammation and regulatory T cells in colon cancer. Toxicol Pathol 2010; 38: 76-87
    • (2010) Toxicol Pathol , vol.38 , pp. 76-87
    • Erdman, S.E.1    Poutahidis, T.2
  • 6
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of mice and men
    • Ziegler SF. FOXP3: of mice and men. Annu Rev Immunol 2006; 24: 209-226
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 7
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 9
    • 84856865635 scopus 로고    scopus 로고
    • Regulatory T cells: Banned cells for decades
    • Loser K, Beissert S. Regulatory T cells: banned cells for decades. J Invest Dermatol 2012; 132: 864-871
    • (2012) J Invest Dermatol , vol.132 , pp. 864-871
    • Loser, K.1    Beissert, S.2
  • 10
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • Beyer M, Schultze JL. Regulatory T cells in cancer. Blood 2006; 108: 804-811
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 11
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 2002; 129: 263-276
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 13
    • 65449149735 scopus 로고    scopus 로고
    • Altered homeostasis of CD4(+) FoxP3(+) regulatory T-cell subpopulations in systemic lupus erythematosus
    • Suen JL, Li HT, Jong YJ, Chiang BL, Yen JH. Altered homeostasis of CD4(+) FoxP3(+) regulatory T-cell subpopulations in systemic lupus erythematosus. Immunology 2009; 127: 196-205
    • (2009) Immunology , vol.127 , pp. 196-205
    • Suen, J.L.1    Li, H.T.2    Jong, Y.J.3    Chiang, B.L.4    Yen, J.H.5
  • 15
    • 33745275219 scopus 로고    scopus 로고
    • Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity
    • Holmén N, Lundgren A, Lundin S, Bergin AM, Rudin A, Sjövall H, Ohman L. Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity. Inflamm Bowel Dis 2006; 12: 447-456
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 447-456
    • Holmén, N.1    Lundgren, A.2    Lundin, S.3    Bergin, A.M.4    Rudin, A.5    Sjövall, H.6    Ohman, L.7
  • 17
    • 79952300978 scopus 로고    scopus 로고
    • Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases
    • Hovhannisyan Z, Treatman J, Littman DR, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology 2011; 140: 957-965
    • (2011) Gastroenterology , vol.140 , pp. 957-965
    • Hovhannisyan, Z.1    Treatman, J.2    Littman, D.R.3    Mayer, L.4
  • 20
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441: 235-238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 22
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 2005; 201: 1061-1067
    • (2005) J Exp Med , vol.201 , pp. 1061-1067
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 23
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
    • Koenen HJ, Smeets RL, Vink PM, van Rijssen E, Boots AM, Joosten I. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008; 112: 2340-2352
    • (2008) Blood , vol.112 , pp. 2340-2352
    • Koenen, H.J.1    Smeets, R.L.2    Vink, P.M.3    van Rijssen, E.4    Boots, A.M.5    Joosten, I.6
  • 26
    • 0141762545 scopus 로고    scopus 로고
    • TGF-beta1 production in inflammatory bowel disease: Differing production patterns in Crohn's disease and ulcerative colitis
    • Del Zotto B, Mumolo G, Pronio AM, Montesani C, Tersigni R, Boirivant M. TGF-beta1 production in inflammatory bowel disease: differing production patterns in Crohn's disease and ulcerative colitis. Clin Exp Immunol 2003; 134: 120-126
    • (2003) Clin Exp Immunol , vol.134 , pp. 120-126
    • Del Zotto, B.1    Mumolo, G.2    Pronio, A.M.3    Montesani, C.4    Tersigni, R.5    Boirivant, M.6
  • 34
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009; 206: 1457-1464
    • (2009) J Exp Med , vol.206 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3    Pardoll, D.M.4    Zeng, D.5    Yu, H.6
  • 36
    • 34248136828 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Cause and immunobiology
    • Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007; 369: 1627-1640
    • (2007) Lancet , vol.369 , pp. 1627-1640
    • Baumgart, D.C.1    Carding, S.R.2
  • 44
    • 35348960243 scopus 로고    scopus 로고
    • Th17: The third member of the effector T cell trilogy
    • Bettelli E, Korn T, Kuchroo VK. Th17: the third member of the effector T cell trilogy. Curr Opin Immunol 2007; 19: 652-657
    • (2007) Curr Opin Immunol , vol.19 , pp. 652-657
    • Bettelli, E.1    Korn, T.2    Kuchroo, V.K.3
  • 45
    • 39449087338 scopus 로고    scopus 로고
    • Th17 cells: Effector T cells with inflammatory properties
    • Korn T, Oukka M, Kuchroo V, Bettelli E. Th17 cells: effector T cells with inflammatory properties. Semin Immunol 2007; 19: 362-371
    • (2007) Semin Immunol , vol.19 , pp. 362-371
    • Korn, T.1    Oukka, M.2    Kuchroo, V.3    Bettelli, E.4
  • 46
    • 0034595970 scopus 로고    scopus 로고
    • Transcriptional regulation of the transforming growth factor-beta-inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB, and AML family members
    • Zhang Y, Derynck R. Transcriptional regulation of the transforming growth factor-beta-inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB, and AML family members. J Biol Chem 2000; 275: 16979-16985
    • (2000) J Biol Chem , vol.275 , pp. 16979-16985
    • Zhang, Y.1    Derynck, R.2
  • 47
    • 79958027367 scopus 로고    scopus 로고
    • Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation
    • Sugai M, Aoki K, Osato M, Nambu Y, Ito K, Taketo MM, Shimizu A. Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation. J Immunol 2011; 186: 6515-6520
    • (2011) J Immunol , vol.186 , pp. 6515-6520
    • Sugai, M.1    Aoki, K.2    Osato, M.3    Nambu, Y.4    Ito, K.5    Taketo, M.M.6    Shimizu, A.7
  • 50
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011; 331: 1565-1570
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 51
  • 56
    • 70349423483 scopus 로고    scopus 로고
    • Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma
    • Sinicrope FA, Rego RL, Ansell SM, Knutson KL, Foster NR, Sargent DJ. Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma. Gastroenterology 2009; 137: 1270-1279
    • (2009) Gastroenterology , vol.137 , pp. 1270-1279
    • Sinicrope, F.A.1    Rego, R.L.2    Ansell, S.M.3    Knutson, K.L.4    Foster, N.R.5    Sargent, D.J.6
  • 61
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser AR, Pitot HC, Dove WF. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990; 247: 322-324
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 62
    • 58649100056 scopus 로고    scopus 로고
    • Inflammation and cancer: IL-6 and STAT3 complete the link
    • Bromberg J, Wang TC. Inflammation and cancer: IL-6 and STAT3 complete the link. Cancer Cell 2009; 15: 79-80
    • (2009) Cancer Cell , vol.15 , pp. 79-80
    • Bromberg, J.1    Wang, T.C.2
  • 64
    • 79958719386 scopus 로고    scopus 로고
    • Colorectal cancer-derived Foxp3(+) IL-17(+) T cells suppress tumour-specific CD8+ T cells
    • Ma C, Dong X. Colorectal cancer-derived Foxp3(+) IL-17(+) T cells suppress tumour-specific CD8+ T cells. Scand J Immunol 2011; 74: 47-51
    • (2011) Scand J Immunol , vol.74 , pp. 47-51
    • Ma, C.1    Dong, X.2
  • 67
    • 47749097074 scopus 로고    scopus 로고
    • The inflammatory chemokines CCL2 and CCL5 in breast cancer
    • Soria G, Ben-Baruch A. The inflammatory chemokines CCL2 and CCL5 in breast cancer. Cancer Lett 2008; 267: 271-285
    • (2008) Cancer Lett , vol.267 , pp. 271-285
    • Soria, G.1    Ben-Baruch, A.2
  • 69
    • 70249122695 scopus 로고    scopus 로고
    • First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127-T regulatory cells
    • Trzonkowski P, Bieniaszewska M, Juścińska J, Dobyszuk A, Krzystyniak A, Marek N, Myśliwska J, Hellmann A. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127-T regulatory cells. Clin Immunol 2009; 133: 22-26
    • (2009) Clin Immunol , vol.133 , pp. 22-26
    • Trzonkowski, P.1    Bieniaszewska, M.2    Juścińska, J.3    Dobyszuk, A.4    Krzystyniak, A.5    Marek, N.6    Myśliwska, J.7    Hellmann, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.