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Volumn 7, Issue 6, 2012, Pages

Phosphorylation of p65(ReLA) on ser 547 by ATM represses NF-κb-dependent transcription of specific genes after genotoxic stress

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LYSINE; SERINE; SYNAPTOTAGMIN I; ANTINEOPLASTIC AGENT; ATM PROTEIN; ATM PROTEIN, HUMAN; ETOPOSIDE; RELA PROTEIN, HUMAN; TRANSCRIPTION FACTOR RELA;

EID: 84862003013     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038246     Document Type: Article
Times cited : (34)

References (49)
  • 1
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • Harper JW, Elledge SJ, (2007) The DNA damage response: ten years after. Mol Cell 28: 739 745.
    • (2007) Mol Cell , vol.28 , pp. 739
    • Harper, J.W.1    Elledge, S.J.2
  • 2
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP, Bartek J, (2009) The DNA-damage response in human biology and disease. Nature 461: 1071 1078.
    • (2009) Nature , vol.461 , pp. 1071
    • Jackson, S.P.1    Bartek, J.2
  • 3
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: taking shape
    • Shiloh Y, (2006) The ATM-mediated DNA-damage response: taking shape. Trends Biochem Sci 31: 402 410.
    • (2006) Trends Biochem Sci , vol.31 , pp. 402
    • Shiloh, Y.1
  • 4
    • 33749249590 scopus 로고    scopus 로고
    • NF-kappaB activation by double-strand breaks
    • Habraken Y, Piette J, (2006) NF-kappaB activation by double-strand breaks. Biochem Pharmacol 72: 1132 1141.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1132
    • Habraken, Y.1    Piette, J.2
  • 5
    • 80054711538 scopus 로고    scopus 로고
    • Importance of PIKKs in NF-kappaB activation by genotoxic stress
    • Sabatel H, Pirlot C, Piette J, Habraken Y, (2011) Importance of PIKKs in NF-kappaB activation by genotoxic stress. Biochem Pharmacol 82: 1371 1383.
    • (2011) Biochem Pharmacol , vol.82 , pp. 1371
    • Sabatel, H.1    Pirlot, C.2    Piette, J.3    Habraken, Y.4
  • 6
    • 38849199203 scopus 로고    scopus 로고
    • Shared Principles in NF-[kappa]B Signaling
    • Hayden MS, Ghosh S, (2008) Shared Principles in NF-[kappa]B Signaling. Cell 132: 344 362.
    • (2008) Cell , vol.132 , pp. 344
    • Hayden, M.S.1    Ghosh, S.2
  • 7
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins ND, (2007) Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 8: 49 62.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 49
    • Perkins, N.D.1
  • 8
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
    • Baud V, Karin M, (2009) Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat Rev Drug Discov 8: 33 40.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 33
    • Baud, V.1    Karin, M.2
  • 9
    • 33750454819 scopus 로고    scopus 로고
    • Mutations in the NF-kappaB signaling pathway: implications for human disease
    • Courtois G, Gilmore TD, (2006) Mutations in the NF-kappaB signaling pathway: implications for human disease. Oncogene 25: 6831 6843.
    • (2006) Oncogene , vol.25 , pp. 6831
    • Courtois, G.1    Gilmore, T.D.2
  • 10
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S, (2004) Signaling to NF-kappaB. Genes Dev 18: 2195 2224.
    • (2004) Genes Dev , vol.18 , pp. 2195
    • Hayden, M.S.1    Ghosh, S.2
  • 11
    • 77953496625 scopus 로고    scopus 로고
    • The NF-kappaB family of transcription factors and its regulation
    • Oeckinghaus A, Ghosh S, (2009) The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 1: a000034.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Oeckinghaus, A.1    Ghosh, S.2
  • 12
    • 33644538632 scopus 로고    scopus 로고
    • Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli
    • Wu ZH, Shi Y, Tibbetts RS, Miyamoto S, (2006) Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli. Science 311: 1141 1146.
    • (2006) Science , vol.311 , pp. 1141
    • Wu, Z.H.1    Shi, Y.2    Tibbetts, R.S.3    Miyamoto, S.4
  • 13
    • 0344305376 scopus 로고    scopus 로고
    • Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
    • Huang TT, Wuerzberger-Davis SM, Wu ZH, Miyamoto S, (2003) Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 115: 565 576.
    • (2003) Cell , vol.115 , pp. 565
    • Huang, T.T.1    Wuerzberger-Davis, S.M.2    Wu, Z.H.3    Miyamoto, S.4
  • 14
    • 77957333810 scopus 로고    scopus 로고
    • A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
    • Hinz M, Stilmann M, Arslan SC, Khanna KK, Dittmar G, (2010) A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation. Mol Cell 40: 63 74.
    • (2010) Mol Cell , vol.40 , pp. 63
    • Hinz, M.1    Stilmann, M.2    Arslan, S.C.3    Khanna, K.K.4    Dittmar, G.5
  • 15
    • 77957374335 scopus 로고    scopus 로고
    • ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
    • Wu ZH, Wong ET, Shi Y, Niu J, Chen Z, (2010) ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. Mol Cell 40: 75 86.
    • (2010) Mol Cell , vol.40 , pp. 75
    • Wu, Z.H.1    Wong, E.T.2    Shi, Y.3    Niu, J.4    Chen, Z.5
  • 16
    • 77953693097 scopus 로고    scopus 로고
    • Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway
    • Huang B, Yang XD, Lamb A, Chen LF, (2010) Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway. Cell Signal 22: 1282 1290.
    • (2010) Cell Signal , vol.22 , pp. 1282
    • Huang, B.1    Yang, X.D.2    Lamb, A.3    Chen, L.F.4
  • 17
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
    • Perkins ND, (2006) Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene 25: 6717 6730.
    • (2006) Oncogene , vol.25 , pp. 6717
    • Perkins, N.D.1
  • 18
    • 17644362355 scopus 로고    scopus 로고
    • DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM
    • Fernandes N, Sun Y, Chen S, Paul P, Shaw RJ, (2005) DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. J Biol Chem 280: 15158 15164.
    • (2005) J Biol Chem , vol.280 , pp. 15158
    • Fernandes, N.1    Sun, Y.2    Chen, S.3    Paul, P.4    Shaw, R.J.5
  • 19
    • 34249947699 scopus 로고    scopus 로고
    • ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
    • Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, 3rd, Hurov KE, et al (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316: 1160 1166.
    • (2007) Science , vol.316 , pp. 1160
    • Matsuoka, S.1    Ballif, B.A.2    Smogorzewska, A.3    McDonald III, E.R.4    Hurov, K.E.5
  • 20
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim ST, Lim DS, Canman CE, Kastan MB, (1999) Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem 274: 37538 37543.
    • (1999) J Biol Chem , vol.274 , pp. 37538
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 21
    • 0032508608 scopus 로고    scopus 로고
    • Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
    • Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, (1998) Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281: 1677 1679.
    • (1998) Science , vol.281 , pp. 1677
    • Canman, C.E.1    Lim, D.S.2    Cimprich, K.A.3    Taya, Y.4    Tamai, K.5
  • 22
    • 49349094024 scopus 로고    scopus 로고
    • Regulation of the RelA (p65) transactivation domain
    • O'Shea JM, Perkins ND, (2008) Regulation of the RelA (p65) transactivation domain. Biochem Soc Trans 36: 603 608.
    • (2008) Biochem Soc Trans , vol.36 , pp. 603
    • O'Shea, J.M.1    Perkins, N.D.2
  • 23
    • 0043172452 scopus 로고    scopus 로고
    • p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor
    • Rocha S, Campbell KJ, Perkins ND, (2003) p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor. Mol Cell 12: 15 25.
    • (2003) Mol Cell , vol.12 , pp. 15
    • Rocha, S.1    Campbell, K.J.2    Perkins, N.D.3
  • 24
    • 77951936396 scopus 로고    scopus 로고
    • Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation
    • O'Shea JM, Perkins ND, (2010) Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation. Biochem J 426: 345 354.
    • (2010) Biochem J , vol.426 , pp. 345
    • O'Shea, J.M.1    Perkins, N.D.2
  • 25
    • 0033118909 scopus 로고    scopus 로고
    • The ATM protein is required for sustained activation of NF-kappaB following DNA damage
    • Piret B, Schoonbroodt S, Piette J, (1999) The ATM protein is required for sustained activation of NF-kappaB following DNA damage. Oncogene 18: 2261 2271.
    • (1999) Oncogene , vol.18 , pp. 2261
    • Piret, B.1    Schoonbroodt, S.2    Piette, J.3
  • 26
    • 0035937809 scopus 로고    scopus 로고
    • ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks
    • Li N, Banin S, Ouyang H, Li GC, Courtois G, (2001) ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks. J Biol Chem 276: 8898 8903.
    • (2001) J Biol Chem , vol.276 , pp. 8898
    • Li, N.1    Banin, S.2    Ouyang, H.3    Li, G.C.4    Courtois, G.5
  • 27
    • 23944471661 scopus 로고    scopus 로고
    • Identification of novel and cell type enriched cofactors of the transcription activation domain of RelA (p65 NF-kappaB)
    • Owen HR, Quadroni M, Bienvenut W, Buerki C, Hottiger MO, (2005) Identification of novel and cell type enriched cofactors of the transcription activation domain of RelA (p65 NF-kappaB). J Proteome Res 4: 1381 1390.
    • (2005) J Proteome Res , vol.4 , pp. 1381
    • Owen, H.R.1    Quadroni, M.2    Bienvenut, W.3    Buerki, C.4    Hottiger, M.O.5
  • 28
    • 78650873024 scopus 로고    scopus 로고
    • Nuclear initiated NF-kappaB signaling: NEMO and ATM take center stage
    • Miyamoto S, (2011) Nuclear initiated NF-kappaB signaling: NEMO and ATM take center stage. Cell Res 21: 116 130.
    • (2011) Cell Res , vol.21 , pp. 116
    • Miyamoto, S.1
  • 29
    • 33646555078 scopus 로고    scopus 로고
    • Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors
    • Campbell KJ, O'Shea JM, Perkins ND, (2006) Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. BMC Cancer 6: 101.
    • (2006) BMC Cancer , vol.6 , pp. 101
    • Campbell, K.J.1    O'Shea, J.M.2    Perkins, N.D.3
  • 30
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD, (2004) The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21: 137 148.
    • (2004) Immunity , vol.21 , pp. 137
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 31
    • 77953859606 scopus 로고    scopus 로고
    • NF-kappaB as a critical link between inflammation and cancer
    • Karin M, (2009) NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb Perspect Biol 1: a000141.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Karin, M.1
  • 32
    • 2942716907 scopus 로고    scopus 로고
    • p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
    • Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC, (2004) p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem 279: 26115 26125.
    • (2004) J Biol Chem , vol.279 , pp. 26115
    • Bohuslav, J.1    Chen, L.F.2    Kwon, H.3    Mu, Y.4    Greene, W.C.5
  • 33
    • 17844386319 scopus 로고    scopus 로고
    • IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
    • Lawrence T, Bebien M, Liu GY, Nizet V, Karin M, (2005) IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 434: 1138 1143.
    • (2005) Nature , vol.434 , pp. 1138
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3    Nizet, V.4    Karin, M.5
  • 34
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-[kappa]B p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300
    • Zhong H, Voll RE, Ghosh S, (1998) Phosphorylation of NF-[kappa]B p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300. Molecular Cell 1: 661 671.
    • (1998) Molecular Cell , vol.1 , pp. 661
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 35
    • 33846783142 scopus 로고    scopus 로고
    • NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage
    • Wuerzberger-Davis SM, Nakamura Y, Seufzer BJ, Miyamoto S, (2007) NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage. Oncogene 26: 641 651.
    • (2007) Oncogene , vol.26 , pp. 641
    • Wuerzberger-Davis, S.M.1    Nakamura, Y.2    Seufzer, B.J.3    Miyamoto, S.4
  • 37
    • 80054811234 scopus 로고    scopus 로고
    • High Throughput Short Interfering RNA (siRNA) Screening of the Human Kinome Identifies Novel Kinases Controlling the Canonical Nuclear Factor-{kappa}B (NF-{kappa}B) Activation Pathway
    • Choudhary S, Rosenblatt KP, Fang L, Tian B, Wu ZH, (2011) High Throughput Short Interfering RNA (siRNA) Screening of the Human Kinome Identifies Novel Kinases Controlling the Canonical Nuclear Factor-{kappa}B (NF-{kappa}B) Activation Pathway. J Biol Chem 286: 37187 37195.
    • (2011) J Biol Chem , vol.286 , pp. 37187
    • Choudhary, S.1    Rosenblatt, K.P.2    Fang, L.3    Tian, B.4    Wu, Z.H.5
  • 38
    • 34447509891 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha
    • Horion J, Gloire G, El Mjiyad N, Quivy V, Vermeulen L, (2007) Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha. J Biol Chem 282: 15383 15393.
    • (2007) J Biol Chem , vol.282 , pp. 15383
    • Horion, J.1    Gloire, G.2    El Mjiyad, N.3    Quivy, V.4    Vermeulen, L.5
  • 39
    • 21344464730 scopus 로고    scopus 로고
    • HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha
    • Place RF, Noonan EJ, Giardina C, (2005) HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha. Biochem Pharmacol 70: 394 406.
    • (2005) Biochem Pharmacol , vol.70 , pp. 394
    • Place, R.F.1    Noonan, E.J.2    Giardina, C.3
  • 40
    • 13944274571 scopus 로고    scopus 로고
    • Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding
    • Hu J, Colburn NH, (2005) Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding. Mol Cancer Res 3: 100 109.
    • (2005) Mol Cancer Res , vol.3 , pp. 100
    • Hu, J.1    Colburn, N.H.2
  • 41
    • 30744458869 scopus 로고    scopus 로고
    • IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300
    • Hoberg JE, Popko AE, Ramsey CS, Mayo MW, (2006) IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Mol Cell Biol 26: 457 471.
    • (2006) Mol Cell Biol , vol.26 , pp. 457
    • Hoberg, J.E.1    Popko, A.E.2    Ramsey, C.S.3    Mayo, M.W.4
  • 42
    • 78650380225 scopus 로고    scopus 로고
    • Regulation of activity and function of the p52 NF-kappaB subunit following DNA damage
    • Barre B, Coqueret O, Perkins ND, (2010) Regulation of activity and function of the p52 NF-kappaB subunit following DNA damage. Cell Cycle 9: 4795 4804.
    • (2010) Cell Cycle , vol.9 , pp. 4795
    • Barre, B.1    Coqueret, O.2    Perkins, N.D.3
  • 43
    • 77952424136 scopus 로고    scopus 로고
    • Cross talk between stimulated NF-kappaB and the tumor suppressor p53
    • Schneider G, Henrich A, Greiner G, Wolf V, Lovas A, (2010) Cross talk between stimulated NF-kappaB and the tumor suppressor p53. Oncogene 29: 2795 2806.
    • (2010) Oncogene , vol.29 , pp. 2795
    • Schneider, G.1    Henrich, A.2    Greiner, G.3    Wolf, V.4    Lovas, A.5
  • 44
    • 79952275158 scopus 로고    scopus 로고
    • The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation
    • Frank AK, Leu JI, Zhou Y, Devarajan K, Nedelko T, (2011) The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation. Mol Cell Biol 31: 1201 1213.
    • (2011) Mol Cell Biol , vol.31 , pp. 1201
    • Frank, A.K.1    Leu, J.I.2    Zhou, Y.3    Devarajan, K.4    Nedelko, T.5
  • 45
    • 0000303499 scopus 로고    scopus 로고
    • ATM associates with and phosphorylates p53: mapping the region of interaction
    • Khanna KK, Keating KE, Kozlov S, Scott S, Gatei M, (1998) ATM associates with and phosphorylates p53: mapping the region of interaction. Nat Genet 20: 398 400.
    • (1998) Nat Genet , vol.20 , pp. 398
    • Khanna, K.K.1    Keating, K.E.2    Kozlov, S.3    Scott, S.4    Gatei, M.5
  • 46
    • 0025963855 scopus 로고
    • Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus
    • Emi N, Friedmann T, Yee JK, (1991) Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus. J Virol 65: 1202 1207.
    • (1991) J Virol , vol.65 , pp. 1202
    • Emi, N.1    Friedmann, T.2    Yee, J.K.3
  • 47
    • 0028866540 scopus 로고
    • Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells
    • Dejardin E, Bonizzi G, Bellahcene A, Castronovo V, Merville MP, (1995) Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells. Oncogene 11: 1835 1841.
    • (1995) Oncogene , vol.11 , pp. 1835
    • Dejardin, E.1    Bonizzi, G.2    Bellahcene, A.3    Castronovo, V.4    Merville, M.P.5
  • 48
    • 0034655179 scopus 로고    scopus 로고
    • Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress
    • Schoonbroodt S, Ferreira V, Best-Belpomme M, Boelaert JR, Legrand-Poels S, (2000) Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress. J Immunol 164: 4292 4300.
    • (2000) J Immunol , vol.164 , pp. 4292
    • Schoonbroodt, S.1    Ferreira, V.2    Best-Belpomme, M.3    Boelaert, J.R.4    Legrand-Poels, S.5
  • 49


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