Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

Nature immunology

Volumn 10, Issue 11, 2009, Pages 1185-1192

  Fife, Brian T ^a   Pauken, Kristen E ^a   Eagar, Todd N ^a   Obu, Takashi ^a   Wu, Jenny ^a   Tang, Qizhi ^a   Azuma, Miyuki ^a   Krummel, Matthew F ^a   Bluestone, Jeffrey A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; B7 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; PDCD1 PROTEIN, MOUSE; PDCD1LG1 PROTEIN, MOUSE; PEPTIDE;

ANIMAL; ARTICLE; C57BL MOUSE; CELL MOTION; DENDRITIC CELL; EXPERIMENTAL DIABETES MELLITUS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; CELL MOVEMENT; DENDRITIC CELLS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; IMMUNE TOLERANCE; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, TRANSGENIC; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION;

EID: 70350433514     PISSN: None     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1790     Document Type: Article

References (0)