Interplay between genetic and epigenetic factors governs common fragile site instability in cancer

Cellular and Molecular Life Sciences

Volumn 71, Issue 23, 2014, Pages 4495-4506

  Ozeri Galai, Efrat ^a   Tur Sinai, Michal ^a   Bester, Assaf C ^a   Kerem, Batsheva ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cancer; DNA damage; Dormant origins; Fragile sites; Genomic instability; Replication

Indexed keywords

DINUCLEOTIDE; VIRUS DNA;

CANCER GENETICS; CARCINOGENESIS; CHROMATIN STRUCTURE; CHROMOSOME BREAKAGE; CHROMOSOME STRUCTURE; COMMON FRAGILE SITE; DNA DAMAGE CHECKPOINT; DNA METHYLATION; DNA REPLICATION; DNA SEQUENCE; DNA STRAND BREAKAGE; EPIGENETICS; GENE AMPLIFICATION; GENE LOCATION; GENETIC ASSOCIATION; GENOMIC INSTABILITY; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PATHOPHYSIOLOGY; PROMOTER REGION; REVIEW; ANIMAL; CHROMOSOME FRAGILE SITE; DNA DAMAGE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; NEOPLASM;

ANIMALS; CHROMOSOME FRAGILE SITES; DNA DAMAGE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HUMANS; NEOPLASMS;

EID: 84922089150     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1719-8     Document Type: Review

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