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Volumn 72, Issue 2, 2012, Pages 460-471

Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 34A; MICRORNA 34C; NATURAL KILLER CELL RECEPTOR NKG2D; NUTLIN 3; PROTEIN P53; PROTEIN ULBP2; UNCLASSIFIED DRUG;

EID: 84855906694     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-1977     Document Type: Article
Times cited : (159)

References (50)
  • 1
    • 77951683908 scopus 로고    scopus 로고
    • Effect of NKG2D ligand expression on host immune responses
    • Champsaur M, Lanier LL. Effect of NKG2D ligand expression on host immune responses. Immunol Rev 2010;235:267-85.
    • (2010) Immunol Rev , vol.235 , pp. 267-285
    • Champsaur, M.1    Lanier, L.L.2
  • 2
    • 0035949563 scopus 로고    scopus 로고
    • Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo
    • DOI 10.1073/pnas.201238598
    • Cerwenka A, Baron JL, Lanier LL. Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proc Natl Acad Sci U S A 2001;98:11521-6. (Pubitemid 32928761)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.20 , pp. 11521-11526
    • Cerwenka, A.1    Baron, J.L.2    Lanier, L.L.3
  • 3
    • 0035855872 scopus 로고    scopus 로고
    • Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
    • DOI 10.1038/35093109
    • Diefenbach A, Jensen ER, Jamieson AM, Raulet DH. Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 2001;413:165-71. (Pubitemid 32867877)
    • (2001) Nature , vol.413 , Issue.6852 , pp. 165-171
    • Diefenbach, A.1    Jensen, E.R.2    Jamieson, A.M.3    Raulet, D.H.4
  • 4
    • 76249116438 scopus 로고    scopus 로고
    • DNAM-1/CD155 interactions promote cytokine and NK cell-mediated suppression of poorly immunogenic melanoma metastases
    • Chan CJ, Andrews DM, McLaughlin NM, Yagita H, Gilfillan S, Colonna M, et al. DNAM-1/CD155 interactions promote cytokine and NK cell-mediated suppression of poorly immunogenic melanoma metastases. J Immunol 2010;184:902-11.
    • (2010) J Immunol , vol.184 , pp. 902-911
    • Chan, C.J.1    Andrews, D.M.2    McLaughlin, N.M.3    Yagita, H.4    Gilfillan, S.5    Colonna, M.6
  • 6
    • 41549163195 scopus 로고    scopus 로고
    • NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
    • Guerra N, Tan YX, Joncker NT, Choy A, Gallardo F, Xiong N, et al. NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 2008;28: 571-80.
    • (2008) Immunity , vol.28 , pp. 571-580
    • Guerra, N.1    Tan, Y.X.2    Joncker, N.T.3    Choy, A.4    Gallardo, F.5    Xiong, N.6
  • 8
    • 0036829733 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: Analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity
    • Pende D, Rivera P, Marcenaro S, Chang CC, Biassoni R, Conte R, et al. Major histocompatibility complex class I-related chain A and UL16- binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. Cancer Res 2002;62:6178-86. (Pubitemid 35244469)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6178-6186
    • Pende, D.1    Rivera, P.2    Marcenaro, S.3    Chang, C.-C.4    Biassoni, R.5    Conte, R.6    Kubin, M.7    Cosman, D.8    Ferrone, S.9    Moretta, L.10    Moretta, A.11
  • 9
    • 37549069898 scopus 로고    scopus 로고
    • NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients
    • Maccalli C, Nonaka D, Piris A, Pende D, Rivoltini L, Castelli C, et al. NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients. Clin Cancer Res 2007;13:7459-68.
    • (2007) Clin Cancer Res , vol.13 , pp. 7459-7468
    • Maccalli, C.1    Nonaka, D.2    Piris, A.3    Pende, D.4    Rivoltini, L.5    Castelli, C.6
  • 10
    • 61449083795 scopus 로고    scopus 로고
    • Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells
    • Schwinn N, Vokhminova D, Sucker A, Textor S, Striegel S, Moll I, et al. Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells. Int J Cancer 2009;124:1594-604.
    • (2009) Int J Cancer , vol.124 , pp. 1594-1604
    • Schwinn, N.1    Vokhminova, D.2    Sucker, A.3    Textor, S.4    Striegel, S.5    Moll, I.6
  • 12
    • 69349104067 scopus 로고    scopus 로고
    • Differential clinical significance of individual NKG2D ligands in melanoma: Soluble ULBP2 as an indicator of poor prognosis superior to S100B
    • Paschen A, Sucker A, Hill B, Moll I, Zapatka M, Nguyen XD, et al. Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B. Clin Cancer Res 2009;15:5208-15.
    • (2009) Clin Cancer Res , vol.15 , pp. 5208-5215
    • Paschen, A.1    Sucker, A.2    Hill, B.3    Moll, I.4    Zapatka, M.5    Nguyen, X.D.6
  • 13
    • 0037126310 scopus 로고    scopus 로고
    • Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • DOI 10.1038/nature01112
    • Groh V, Wu J, Yee C, Spies T. Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 2002;419: 734-8. (Pubitemid 35177960)
    • (2002) Nature , vol.419 , Issue.6908 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 15
    • 0037108517 scopus 로고    scopus 로고
    • Cutting edge: Down-regulation of MICA on human tumors by proteolytic shedding
    • Salih HR, Rammensee HG, Steinle A. Cutting edge: down-regulation of MICA on human tumors by proteolytic shedding. J Immunol 2002;169: 4098-102. (Pubitemid 35178177)
    • (2002) Journal of Immunology , vol.169 , Issue.8 , pp. 4098-4102
    • Salih, H.R.1    Rammensee, H.-G.2    Steinle, A.3
  • 16
    • 4344624611 scopus 로고    scopus 로고
    • Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shadding in prostate cancer
    • DOI 10.1172/JCI200422206
    • Wu JD, Higgins LM, Steinle A, Cosman D, Haugk K, Plymate SR. Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer. J Clin Invest 2004;114:560-8. (Pubitemid 39572106)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.4 , pp. 560-568
    • Wu, J.D.1    Higgins, L.M.2    Steinle, A.3    Cosman, D.4    Haugk, K.5    Plymate, S.R.6
  • 17
    • 33748323243 scopus 로고    scopus 로고
    • Soluble MICB in malignant diseases: Analysis of diagnostic significance and correlation with soluble MICA
    • DOI 10.1007/s00262-006-0167-1
    • Holdenrieder S, Stieber P, Peterfi A, Nagel D, Steinle A, Salih HR. Soluble MICB in malignant diseases: analysis of diagnostic significance and correlation with soluble MICA. Cancer Immunol Immunother 2006;55:1584-9. (Pubitemid 44327846)
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , Issue.12 , pp. 1584-1589
    • Holdenrieder, S.1    Stieber, P.2    Peterfi, A.3    Nagel, D.4    Steinle, A.5    Salih, H.R.6
  • 18
    • 0041737499 scopus 로고    scopus 로고
    • Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia
    • DOI 10.1182/blood-2003-01-0019
    • Salih HR, Antropius H, Gieseke F, Lutz SZ, Kanz L, Rammensee HG, et al. Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia. Blood 2003;102: 1389-96. (Pubitemid 36988048)
    • (2003) Blood , vol.102 , Issue.4 , pp. 1389-1396
    • Salih, H.R.1    Antropius, H.2    Gieseke, F.3    Lutz, S.Z.4    Kanz, L.5    Rammensee, H.-G.6    Steinle, A.7
  • 19
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • DOI 10.1038/nature03884
    • Gasser S, Orsulic S, Brown EJ, Raulet DH. The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 2005;436:1186-90. (Pubitemid 41232299)
    • (2005) Nature , vol.436 , Issue.7054 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 20
    • 0035286345 scopus 로고    scopus 로고
    • Costimulation of CD8alphabeta T cell by NKG2D via engagement by MIC induced on virus-infected cells
    • DOI 10.1038/85321
    • Groh V, Rhinehart R, Randolph-Habecker J, Topp MS, Riddell SR, Spies T. Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat Immunol 2001; 2:255-60. (Pubitemid 33706003)
    • (2001) Nature Immunology , vol.2 , Issue.3 , pp. 255-260
    • Groh, V.1    Rhinehart, R.2    Randolph-Habecker, J.3    Topp, M.S.4    Riddell, S.R.5    Spies, T.6
  • 21
    • 33846245583 scopus 로고    scopus 로고
    • Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D
    • Venkataraman GM, Suciu D, Groh V, Boss JM, Spies T. Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D. J Immunol 2007;178:961-9. (Pubitemid 46095169)
    • (2007) Journal of Immunology , vol.178 , Issue.2 , pp. 961-969
    • Venkataraman, G.M.1    Suciu, D.2    Groh, V.3    Boss, J.M.4    Spies, T.5
  • 22
    • 36249023845 scopus 로고    scopus 로고
    • In vivo expression pattern of MICA and MICB and its relevance to auto-immunity and cancer
    • Schrambach S, Ardizzone M, Leymarie V, Sibilia J, Bahram S. In vivo expression pattern of MICA and MICB and its relevance to auto-immunity and cancer. PLoS One 2007;2:e518.
    • (2007) PLoS One , vol.2
    • Schrambach, S.1    Ardizzone, M.2    Leymarie, V.3    Sibilia, J.4    Bahram, S.5
  • 23
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
    • Huntzinger E, Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 2011;12:99-110.
    • (2011) Nat Rev Genet , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 24
    • 33745220023 scopus 로고    scopus 로고
    • The coincidence of chromosome 15 aberrations and beta2- Microglobulin gene mutations is causative for the total loss of human leukocyte antigen class I expression in melanoma
    • Paschen A, Arens N, Sucker A, Greulich-Bode KM, Fonsatti E, Gloghini A, et al. The coincidence of chromosome 15 aberrations and beta2- microglobulin gene mutations is causative for the total loss of human leukocyte antigen class I expression in melanoma. Clin Cancer Res 2006;12:3297-305.
    • (2006) Clin Cancer Res , vol.12 , pp. 3297-3305
    • Paschen, A.1    Arens, N.2    Sucker, A.3    Greulich-Bode, K.M.4    Fonsatti, E.5    Gloghini, A.6
  • 25
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ 2010;17:193-9.
    • (2010) Cell Death Differ , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 26
    • 76749102887 scopus 로고    scopus 로고
    • E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis
    • Lize M, Pilarski S, Dobbelstein M. E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis. Cell Death Differ 2010;17:452-8.
    • (2010) Cell Death Differ , vol.17 , pp. 452-458
    • Lize, M.1    Pilarski, S.2    Dobbelstein, M.3
  • 28
    • 44849091255 scopus 로고    scopus 로고
    • Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence
    • Kumamoto K, Spillare EA, Fujita K, Horikawa I, Yamashita T, Appella E, et al. Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence. Cancer Res 2008;68:3193-203.
    • (2008) Cancer Res , vol.68 , pp. 3193-3203
    • Kumamoto, K.1    Spillare, E.A.2    Fujita, K.3    Horikawa, I.4    Yamashita, T.5    Appella, E.6
  • 29
    • 77954613267 scopus 로고    scopus 로고
    • The prognostic significance of solubleNKG2D ligands in B-cell chronic lymphocytic leukemia
    • Nückel H, Switala M, Sellmann L, Horn PA, Dürig J, Dührsen U, et al. The prognostic significance of solubleNKG2D ligands in B-cell chronic lymphocytic leukemia. Leukemia 2010;24:1152-9.
    • (2010) Leukemia , vol.24 , pp. 1152-1159
    • Nückel, H.1    Switala, M.2    Sellmann, L.3    Horn, P.A.4    Dürig, J.5    Dührsen, U.6
  • 30
    • 40449129958 scopus 로고    scopus 로고
    • Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors
    • DOI 10.1158/0008-5472.CAN-07-2973
    • Vales-Gomez M, Chisholm SE, Cassady-Cain RL, Roda-Navarro P, Reyburn HT. Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors. Cancer Res 2008;68: 1546-54. (Pubitemid 351346864)
    • (2008) Cancer Research , vol.68 , Issue.5 , pp. 1546-1554
    • Vales-Gomez, M.1    Chisholm, S.E.2    Cassady-Cain, R.L.3    Roda-Navarro, P.4    Reyburn, H.T.5
  • 31
    • 50049115540 scopus 로고    scopus 로고
    • Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
    • Stern-Ginossar N, Gur C, Biton M, Horwitz E, Elboim M, Stanietsky N, et al. Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D. Nat Immunol 2008;9: 1065-73.
    • (2008) Nat Immunol , vol.9 , pp. 1065-1073
    • Stern-Ginossar, N.1    Gur, C.2    Biton, M.3    Horwitz, E.4    Elboim, M.5    Stanietsky, N.6
  • 32
    • 59849122968 scopus 로고    scopus 로고
    • Cutting edge: Down-regulation of MHC class I-related chain A on tumor cells by IFN-gamma- induced microRNA
    • Yadav D, Ngolab J, Lim RS, Krishnamurthy S, Bui JD. Cutting edge: down-regulation of MHC class I-related chain A on tumor cells by IFN-gamma- induced microRNA. J Immunol 2009;182:39-43.
    • (2009) J Immunol , vol.182 , pp. 39-43
    • Yadav, D.1    Ngolab, J.2    Lim, R.S.3    Krishnamurthy, S.4    Bui, J.D.5
  • 33
    • 77955928100 scopus 로고    scopus 로고
    • The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination
    • Nachmani D, Lankry D, Wolf DG, Mandelboim O. The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination. Nat Immunol 2010;11: 806-13.
    • (2010) Nat Immunol , vol.11 , pp. 806-813
    • Nachmani, D.1    Lankry, D.2    Wolf, D.G.3    Mandelboim, O.4
  • 34
    • 70350221952 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
    • Li Y, Guessous F, Zhang Y, Dipierro C, Kefas B, Johnson E, et al. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res 2009;69:7569-76.
    • (2009) Cancer Res , vol.69 , pp. 7569-7576
    • Li, Y.1    Guessous, F.2    Zhang, Y.3    Dipierro, C.4    Kefas, B.5    Johnson, E.6
  • 37
    • 77956937548 scopus 로고    scopus 로고
    • Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation
    • Aranha MM, Santos DM, Xavier JM, Low WC, Steer CJ, Solá S, et al. Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation. BMC Genomics 2010;11: 514.
    • (2010) BMC Genomics , vol.11 , pp. 514
    • Aranha, M.M.1    Santos, D.M.2    Xavier, J.M.3    Low, W.C.4    Steer, C.J.5    Solá, S.6
  • 38
    • 77956640572 scopus 로고    scopus 로고
    • MiRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells
    • Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S, et al. miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells. FASEB J 2010;24:3255-63.
    • (2010) FASEB J , vol.24 , pp. 3255-3263
    • Tarantino, C.1    Paolella, G.2    Cozzuto, L.3    Minopoli, G.4    Pastore, L.5    Parisi, S.6
  • 40
    • 70350111289 scopus 로고    scopus 로고
    • MiR-449a and miR- 449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A
    • Yang X, Feng M, Jiang X, Wu Z, Li Z, Aau M, et al. miR-449a and miR- 449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev 2009;23:2388-93.
    • (2009) Genes Dev , vol.23 , pp. 2388-2393
    • Yang, X.1    Feng, M.2    Jiang, X.3    Wu, Z.4    Li, Z.5    Aau, M.6
  • 41
    • 78649846540 scopus 로고    scopus 로고
    • MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia
    • Lize M, Herr C, Klimke A, Bals R, Dobbelstein M. MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia. Cell Cycle 2010;9:4579-83.
    • (2010) Cell Cycle , vol.9 , pp. 4579-4583
    • Lize, M.1    Herr, C.2    Klimke, A.3    Bals, R.4    Dobbelstein, M.5
  • 46
    • 80052793188 scopus 로고    scopus 로고
    • Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2
    • Textor S, Fiegler N, Arnold A, Porgador A, Hofmann TG, Cerwenka A. Human NK Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2. Cancer Res 2011;71:5998-6009.
    • (2011) Cancer Res , vol.71 , pp. 5998-6009
    • Textor, S.1    Fiegler, N.2    Arnold, A.3    Porgador, A.4    Hofmann, T.G.5    Cerwenka, A.6    Human, N.K.7
  • 49
    • 80051613002 scopus 로고    scopus 로고
    • Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis
    • Kaller M, Liffers ST, Oeljeklaus S, Kuhlmann K, Röh S, Hoffmann R, et al. Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis. Mol Cell Proteomics 2011;10: M111 010462.
    • (2011) Mol Cell Proteomics , vol.10
    • Kaller, M.1    Liffers, S.T.2    Oeljeklaus, S.3    Kuhlmann, K.4    Röh, S.5    Hoffmann, R.6
  • 50
    • 78649378267 scopus 로고    scopus 로고
    • MicroRNA functions in stress responses
    • Leung AK, Sharp PA. MicroRNA functions in stress responses. Mol Cell 2010;40:205-15.
    • (2010) Mol Cell , vol.40 , pp. 205-215
    • Leung, A.K.1    Sharp, P.A.2


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