-
1
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T., Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34:637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
2
-
-
84902951706
-
Sensing viral invasion by RIG-I like receptors
-
Yoo J.S., Kato H., Fujita T. Sensing viral invasion by RIG-I like receptors. Curr Opin Microbiol 2014, 20C:131-138.
-
(2014)
Curr Opin Microbiol
, vol.20 C
, pp. 131-138
-
-
Yoo, J.S.1
Kato, H.2
Fujita, T.3
-
3
-
-
84880426658
-
The cGAS-STING pathway for DNA sensing
-
Xiao T.S., Fitzgerald K.A. The cGAS-STING pathway for DNA sensing. Mol Cell 2013, 51:135-139.
-
(2013)
Mol Cell
, vol.51
, pp. 135-139
-
-
Xiao, T.S.1
Fitzgerald, K.A.2
-
4
-
-
84871484827
-
The broad-spectrum antiviral functions of IFIT and IFITM proteins
-
Diamond M.S., Farzan M. The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat Rev Immunol 2013, 13:46-57.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 46-57
-
-
Diamond, M.S.1
Farzan, M.2
-
5
-
-
0019286084
-
The role of interferon in immediate hypersensitivity and autoimmune diseases
-
Hooks J.J., Moutsopoulos H.M., Notkins A.L. The role of interferon in immediate hypersensitivity and autoimmune diseases. Ann NY Acad Sci 1980, 350:21-32.
-
(1980)
Ann NY Acad Sci
, vol.350
, pp. 21-32
-
-
Hooks, J.J.1
Moutsopoulos, H.M.2
Notkins, A.L.3
-
6
-
-
80053495592
-
Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway
-
Higgs B.W., Liu Z., White B., Zhu W., White W.I., et al. Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway. Ann Rheum Dis 2011, 70:2029-2036.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 2029-2036
-
-
Higgs, B.W.1
Liu, Z.2
White, B.3
Zhu, W.4
White, W.I.5
-
7
-
-
84905456707
-
Advances in understanding the role of type I interferons in systemic lupus erythematosus
-
Crow M.K. Advances in understanding the role of type I interferons in systemic lupus erythematosus. Curr Opin Rheumatol 2014, 26:467-474.
-
(2014)
Curr Opin Rheumatol
, vol.26
, pp. 467-474
-
-
Crow, M.K.1
-
8
-
-
84894028950
-
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5
-
Funabiki M., Kato H., Miyachi Y., Toki H., Motegi H., et al. Autoimmune disorders associated with gain of function of the intracellular sensor MDA5. Immunity 2014, 40:199-212.
-
(2014)
Immunity
, vol.40
, pp. 199-212
-
-
Funabiki, M.1
Kato, H.2
Miyachi, Y.3
Toki, H.4
Motegi, H.5
-
9
-
-
84899534322
-
MDA5 and autoimmune disease
-
Miner J.J., Diamond M.S. MDA5 and autoimmune disease. Nat Genet 2014, 46:418-419.
-
(2014)
Nat Genet
, vol.46
, pp. 418-419
-
-
Miner, J.J.1
Diamond, M.S.2
-
10
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004, 5:730-737.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
-
11
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H., Takeuchi O., Sato S., Yoneyama M., Yamamoto M., et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006, 441:101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
-
12
-
-
76549109497
-
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
-
Satoh T., Kato H., Kumagai Y., Yoneyama M., Sato S., et al. LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. PNAS 2010, 107:1512-1517.
-
(2010)
PNAS
, vol.107
, pp. 1512-1517
-
-
Satoh, T.1
Kato, H.2
Kumagai, Y.3
Yoneyama, M.4
Sato, S.5
-
13
-
-
34248168157
-
Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses
-
Venkataraman T., Valdes M., Elsby R., Kakuta S., Caceres G., et al. Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses. J Immunol 2007, 178:6444-6455.
-
(2007)
J Immunol
, vol.178
, pp. 6444-6455
-
-
Venkataraman, T.1
Valdes, M.2
Elsby, R.3
Kakuta, S.4
Caceres, G.5
-
14
-
-
80054685883
-
Structural insights into RNA recognition by RIG-I
-
Luo D., Ding S.C., Vela A., Kohlway A., Lindenbach B.D., et al. Structural insights into RNA recognition by RIG-I. Cell 2011, 147:409-422.
-
(2011)
Cell
, vol.147
, pp. 409-422
-
-
Luo, D.1
Ding, S.C.2
Vela, A.3
Kohlway, A.4
Lindenbach, B.D.5
-
15
-
-
80755140529
-
55 Amino acid linker between helicase and carboxyl terminal domains of RIG-I functions as a critical repression domain and determines inter-domain conformation
-
Kageyama M., Takahasi K., Narita R., Hirai R., Yoneyama M., et al. 55 Amino acid linker between helicase and carboxyl terminal domains of RIG-I functions as a critical repression domain and determines inter-domain conformation. Biochem Biophys Res Commun 2011, 415:75-81.
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 75-81
-
-
Kageyama, M.1
Takahasi, K.2
Narita, R.3
Hirai, R.4
Yoneyama, M.5
-
16
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M., Kikuchi M., Matsumoto K., Imaizumi T., Miyagishi M., et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 2005, 175:2851-2858.
-
(2005)
J Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
-
17
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V., Ellegast J., Kim S., Brzozka K., Jung A., et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006, 314:994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
-
18
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
-
Pichlmair A., Schulz O., Tan C.P., Naslund T.I., Liljestrom P., et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006, 314:997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
-
19
-
-
68049089651
-
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
-
Schlee M., Roth A., Hornung V., Hagmann C.A., Wimmenauer V., et al. Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. Immunity 2009, 31:25-34.
-
(2009)
Immunity
, vol.31
, pp. 25-34
-
-
Schlee, M.1
Roth, A.2
Hornung, V.3
Hagmann, C.A.4
Wimmenauer, V.5
-
20
-
-
67749133995
-
5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
-
Schmidt A., Schwerd T., Hamm W., Hellmuth J.C., Cui S., et al. 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I. PNAS 2009, 106:12067-12072.
-
(2009)
PNAS
, vol.106
, pp. 12067-12072
-
-
Schmidt, A.1
Schwerd, T.2
Hamm, W.3
Hellmuth, J.C.4
Cui, S.5
-
21
-
-
75749140581
-
RIG-I detects viral genomic RNA during negative-strand RNA virus infection
-
Rehwinkel J., Tan C.P., Goubau D., Schulz O., Pichlmair A., et al. RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 2010, 140:397-408.
-
(2010)
Cell
, vol.140
, pp. 397-408
-
-
Rehwinkel, J.1
Tan, C.P.2
Goubau, D.3
Schulz, O.4
Pichlmair, A.5
-
22
-
-
84883487585
-
ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon
-
Patel J.R., Jain A., Chou Y.Y., Baum A., Ha T., et al. ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon. EMBO Rep 2013, 14:780-787.
-
(2013)
EMBO Rep
, vol.14
, pp. 780-787
-
-
Patel, J.R.1
Jain, A.2
Chou, Y.Y.3
Baum, A.4
Ha, T.5
-
23
-
-
46949097299
-
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
-
Kato H., Takeuchi O., Mikamo-Satoh E., Hirai R., Kawai T., et al. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J Exp Med 2008, 205:1601-1610.
-
(2008)
J Exp Med
, vol.205
, pp. 1601-1610
-
-
Kato, H.1
Takeuchi, O.2
Mikamo-Satoh, E.3
Hirai, R.4
Kawai, T.5
-
24
-
-
39649092731
-
Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses
-
Takahasi K., Yoneyama M., Nishihori T., Hirai R., Kumeta H., et al. Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell 2008, 29:428-440.
-
(2008)
Mol Cell
, vol.29
, pp. 428-440
-
-
Takahasi, K.1
Yoneyama, M.2
Nishihori, T.3
Hirai, R.4
Kumeta, H.5
-
25
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth R.B., Sun L., Ea C.K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005, 122:669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
26
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T., Takahashi K., Sato S., Coban C., Kumar H., et al. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 2005, 6:981-988.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
-
27
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu L.G., Wang Y.Y., Han K.J., Li L.Y., Zhai Z., et al. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell 2005, 19:727-740.
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
-
28
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E., Curran J., Hofmann K., Moradpour D., Binder M., et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005, 437:1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
-
29
-
-
33646592188
-
The specific and essential role of MAVS in antiviral innate immune responses
-
Sun Q., Sun L., Liu H.H., Chen X., Seth R.B., et al. The specific and essential role of MAVS in antiviral innate immune responses. Immunity 2006, 24:633-642.
-
(2006)
Immunity
, vol.24
, pp. 633-642
-
-
Sun, Q.1
Sun, L.2
Liu, H.H.3
Chen, X.4
Seth, R.B.5
-
30
-
-
33745814424
-
Essential role of IPS-1 in innate immune responses against RNA viruses
-
Kumar H., Kawai T., Kato H., Sato S., Takahashi K., et al. Essential role of IPS-1 in innate immune responses against RNA viruses. J Exp Med 2006, 203:1795-1803.
-
(2006)
J Exp Med
, vol.203
, pp. 1795-1803
-
-
Kumar, H.1
Kawai, T.2
Kato, H.3
Sato, S.4
Takahashi, K.5
-
31
-
-
84872604349
-
Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5
-
Wu B., Peisley A., Richards C., Yao H., Zeng X., et al. Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5. Cell 2013, 152:276-289.
-
(2013)
Cell
, vol.152
, pp. 276-289
-
-
Wu, B.1
Peisley, A.2
Richards, C.3
Yao, H.4
Zeng, X.5
-
32
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou F., Sun L., Zheng H., Skaug B., Jiang Q.X., et al. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 2011, 146:448-461.
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
-
33
-
-
77957666242
-
Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1
-
Onoguchi K., Onomoto K., Takamatsu S., Jogi M., Takemura A., et al. Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1. PLoS Pathog 2010, 6:e1001012.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1001012
-
-
Onoguchi, K.1
Onomoto, K.2
Takamatsu, S.3
Jogi, M.4
Takemura, A.5
-
34
-
-
84865060036
-
Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity
-
Onomoto K., Jogi M., Yoo J.S., Narita R., Morimoto S., et al. Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PLoS One 2012, 7:e43031.
-
(2012)
PLoS One
, vol.7
, pp. e43031
-
-
Onomoto, K.1
Jogi, M.2
Yoo, J.S.3
Narita, R.4
Morimoto, S.5
-
35
-
-
84897407806
-
DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation
-
Yoo J.S., Takahasi K., Ng C.S., Ouda R., Onomoto K., et al. DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation. PLoS Pathog 2014, 10:e1004012.
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004012
-
-
Yoo, J.S.1
Takahasi, K.2
Ng, C.S.3
Ouda, R.4
Onomoto, K.5
-
36
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H., Bscheider M., Gross O., Finger K., Roth S., et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol 2010, 11:63-69.
-
(2010)
Nat Immunol
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
-
37
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000, 408:740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
-
38
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F., Hemmi H., Hochrein H., Ampenberger F., Kirschning C., et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004, 303:1526-1529.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
-
39
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold S.S., Kaisho T., Hemmi H., Akira S., Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004, 303:1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis e Sousa, C.5
-
40
-
-
36048962438
-
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
-
Deane J.A., Pisitkun P., Barrett R.S., Feigenbaum L., Town T., et al. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 2007, 27:801-810.
-
(2007)
Immunity
, vol.27
, pp. 801-810
-
-
Deane, J.A.1
Pisitkun, P.2
Barrett, R.S.3
Feigenbaum, L.4
Town, T.5
-
41
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun P., Deane J.A., Difilippantonio M.J., Tarasenko T., Satterthwaite A.B., et al. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 2006, 312:1669-1672.
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
-
42
-
-
0034114882
-
Features of systemic lupus erythematosus in Dnase1-deficient mice
-
Napirei M., Karsunky H., Zevnik B., Stephan H., Mannherz H.G., et al. Features of systemic lupus erythematosus in Dnase1-deficient mice. Nat Genet 2000, 25:177-181.
-
(2000)
Nat Genet
, vol.25
, pp. 177-181
-
-
Napirei, M.1
Karsunky, H.2
Zevnik, B.3
Stephan, H.4
Mannherz, H.G.5
-
43
-
-
80051619284
-
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-alpha and serologic autoimmunity in lupus patients
-
Robinson T., Kariuki S.N., Franek B.S., Kumabe M., Kumar A.A., et al. Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-alpha and serologic autoimmunity in lupus patients. J Immunol 2011, 187:1298-1303.
-
(2011)
J Immunol
, vol.187
, pp. 1298-1303
-
-
Robinson, T.1
Kariuki, S.N.2
Franek, B.S.3
Kumabe, M.4
Kumar, A.A.5
-
44
-
-
84856574619
-
Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity
-
Crampton S.P., Deane J.A., Feigenbaum L., Bolland S. Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity. J Immunol 2012, 188:1451-1459.
-
(2012)
J Immunol
, vol.188
, pp. 1451-1459
-
-
Crampton, S.P.1
Deane, J.A.2
Feigenbaum, L.3
Bolland, S.4
-
45
-
-
77950400643
-
Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity
-
Crow Y.J., Rehwinkel J. Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity. Hum Mol Genet 2009, 18:R130-R136.
-
(2009)
Hum Mol Genet
, vol.18
, pp. R130-R136
-
-
Crow, Y.J.1
Rehwinkel, J.2
-
46
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun L., Wu J., Du F., Chen X., Chen Z.J. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013, 339:786-791.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
47
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa H., Ma Z., Barber G.N. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 2009, 461:788-792.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
48
-
-
33746581694
-
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
-
Crow Y.J., Hayward B.E., Parmar R., Robins P., Leitch A., et al. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus. Nat Genet 2006, 38:917-920.
-
(2006)
Nat Genet
, vol.38
, pp. 917-920
-
-
Crow, Y.J.1
Hayward, B.E.2
Parmar, R.3
Robins, P.4
Leitch, A.5
-
49
-
-
34548327158
-
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus
-
Lee-Kirsch M.A., Gong M., Chowdhury D., Senenko L., Engel K., et al. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet 2007, 39:1065-1067.
-
(2007)
Nat Genet
, vol.39
, pp. 1065-1067
-
-
Lee-Kirsch, M.A.1
Gong, M.2
Chowdhury, D.3
Senenko, L.4
Engel, K.5
-
50
-
-
84899495767
-
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
-
Rice G.I., del Toro Duany Y., Jenkinson E.M., Forte G.M., Anderson B.H., et al. Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nat Genet 2014, 46:503-509.
-
(2014)
Nat Genet
, vol.46
, pp. 503-509
-
-
Rice, G.I.1
del Toro Duany, Y.2
Jenkinson, E.M.3
Forte, G.M.4
Anderson, B.H.5
-
51
-
-
84904004005
-
Aicardi-Goutieres syndrome is caused by IFIH1 mutations
-
Oda H., Nakagawa K., Abe J., Awaya T., Funabiki M., et al. Aicardi-Goutieres syndrome is caused by IFIH1 mutations. Am J Hum Genet 2014, 95:121-125.
-
(2014)
Am J Hum Genet
, vol.95
, pp. 121-125
-
-
Oda, H.1
Nakagawa, K.2
Abe, J.3
Awaya, T.4
Funabiki, M.5
-
52
-
-
65249131713
-
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
-
Nejentsev S., Walker N., Riches D., Egholm M., Todd J.A. Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 2009, 324:387-389.
-
(2009)
Science
, vol.324
, pp. 387-389
-
-
Nejentsev, S.1
Walker, N.2
Riches, D.3
Egholm, M.4
Todd, J.A.5
-
53
-
-
57149101123
-
Role of coxsackievirus B4 in the pathogenesis of type 1 diabetes
-
Jaidane H., Hober D. Role of coxsackievirus B4 in the pathogenesis of type 1 diabetes. Diabete Metab 2008, 34:537-548.
-
(2008)
Diabete Metab
, vol.34
, pp. 537-548
-
-
Jaidane, H.1
Hober, D.2
|